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Items: 22


Optimization and validation of a flow cytometric method for immunophenotyping peripheral blood lymphocytes from cynomolgus monkeys (Macaca fascicularis).

Baker DL, Finco-Kent DL, Reagan WJ, Conklyn MJ, Kawabata TT.

Vet Clin Pathol. 2008 Mar;37(1):42-8. doi: 10.1111/j.1939-165X.2008.00014.x.


Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor.

Changelian PS, Flanagan ME, Ball DJ, Kent CR, Magnuson KS, Martin WH, Rizzuti BJ, Sawyer PS, Perry BD, Brissette WH, McCurdy SP, Kudlacz EM, Conklyn MJ, Elliott EA, Koslov ER, Fisher MB, Strelevitz TJ, Yoon K, Whipple DA, Sun J, Munchhof MJ, Doty JL, Casavant JM, Blumenkopf TA, Hines M, Brown MF, Lillie BM, Subramanyam C, Shang-Poa C, Milici AJ, Beckius GE, Moyer JD, Su C, Woodworth TG, Gaweco AS, Beals CR, Littman BH, Fisher DA, Smith JF, Zagouras P, Magna HA, Saltarelli MJ, Johnson KS, Nelms LF, Des Etages SG, Hayes LS, Kawabata TT, Finco-Kent D, Baker DL, Larson M, Si MS, Paniagua R, Higgins J, Holm B, Reitz B, Zhou YJ, Morris RE, O'Shea JJ, Borie DC.

Science. 2003 Oct 31;302(5646):875-8.


CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases.

Gladue RP, Tylaska LA, Brissette WH, Lira PD, Kath JC, Poss CS, Brown MF, Paradis TJ, Conklyn MJ, Ogborne KT, McGlynn MA, Lillie BM, DiRico AP, Mairs EN, McElroy EB, Martin WH, Stock IA, Shepard RM, Showell HJ, Neote K.

J Biol Chem. 2003 Oct 17;278(42):40473-80. Epub 2003 Aug 7.


trans-3-Benzyl-4-hydroxy-7-chromanylbenzoic acid derivatives as antagonists of the leukotriene B4 (LTB4) receptor.

Reiter LA, Koch K, Piscopio AD, Showell HJ, Alpert R, Biggers MS, Chambers RJ, Conklyn MJ, Cooper K, Cortina SR, Dibrino JN, Dominy BW, Farrell CA, Hingorani GP, Martinelli GJ, Ramchandani M, Wright KF.

Bioorg Med Chem Lett. 1998 Jul 21;8(14):1781-6.


The preclinical pharmacological profile of the potent and selective leukotriene B4 antagonist CP-195543.

Showell HJ, Conklyn MJ, Alpert R, Hingorani GP, Wright KF, Smith MA, Stam E, Salter ED, Scampoli DN, Meltzer S, Reiter LA, Koch K, Piscopio AD, Cortina SR, Lopez-Anaya A, Pettipher ER, Milici AJ, Griffiths RJ.

J Pharmacol Exp Ther. 1998 Jun;285(3):946-54.


Pharmacokinetics and pharmacodynamics of the leukotriene B4 receptor antagonist CP-105,696 in man following single oral administration.

Liston TE, Conklyn MJ, Houser J, Wilner KD, Johnson A, Apseloff G, Whitacre C, Showell HJ.

Br J Clin Pharmacol. 1998 Feb;45(2):115-21.


Production and characterization of guinea pig IL-5 in baculovirus-infected insect cells.

Mansour M, Karmilowicz M, Hawrylik SJ, Nalcerio B, Angilly J, Conklyn MJ, Lilly CM, Drazen JM, Lee SE, Auperin DD, De Wet JR, Cohan VL, Showell HJ, Danley DE.

Am J Physiol. 1996 Jun;270(6 Pt 1):L1002-7.


Characterization of the pharmacological profile of the potent LTB4 antagonist CP-105,696 on murine LTB4 receptors in vitro.

Showell HJ, Breslow R, Conklyn MJ, Hingorani GP, Koch K.

Br J Pharmacol. 1996 Mar;117(6):1127-32.


In vitro and in vivo effects of leukotriene B4 antagonism in a primate model of asthma.

Turner CR, Breslow R, Conklyn MJ, Andresen CJ, Patterson DK, Lopez-Anaya A, Owens B, Lee P, Watson JW, Showell HJ.

J Clin Invest. 1996 Jan 15;97(2):381-7.


Expression and biologic characterization of the murine chemokine KC.

Bozic CR, Kolakowski LF Jr, Gerard NP, Garcia-Rodriguez C, von Uexkull-Guldenband C, Conklyn MJ, Breslow R, Showell HJ, Gerard C.

J Immunol. 1995 Jun 1;154(11):6048-57.


The in vitro and in vivo pharmacologic activity of the potent and selective leukotriene B4 receptor antagonist CP-105696.

Showell HJ, Pettipher ER, Cheng JB, Breslow R, Conklyn MJ, Farrell CA, Hingorani GP, Salter ED, Hackman BC, Wimberly DJ, et al.

J Pharmacol Exp Ther. 1995 Apr;273(1):176-84.


The Duffy antigen/receptor for chemokines (DARC) is expressed in endothelial cells of Duffy negative individuals who lack the erythrocyte receptor.

Peiper SC, Wang ZX, Neote K, Martin AW, Showell HJ, Conklyn MJ, Ogborne K, Hadley TJ, Lu ZH, Hesselgesser J, Horuk R.

J Exp Med. 1995 Apr 1;181(4):1311-7.


Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis.

Griffiths RJ, Pettipher ER, Koch K, Farrell CA, Breslow R, Conklyn MJ, Smith MA, Hackman BC, Wimberly DJ, Milici AJ, et al.

Proc Natl Acad Sci U S A. 1995 Jan 17;92(2):517-21.


The murine interleukin 8 type B receptor homologue and its ligands. Expression and biological characterization.

Bozic CR, Gerard NP, von Uexkull-Guldenband C, Kolakowski LF Jr, Conklyn MJ, Breslow R, Showell HJ, Gerard C.

J Biol Chem. 1994 Nov 25;269(47):29355-8.


Structural and (patho)physiological diversity of PAF.

Pinckard RN, Woodard DS, Showell HJ, Conklyn MJ, Novak MJ, McManus LM.

Clin Rev Allergy. 1994 Winter;12(4):329-59. Review. No abstract available.


Tyrosine phosphorylation is an early signaling event common to Fc receptor crosslinking in human neutrophils and rat basophilic leukemia cells (RBL-2H3).

Connelly PA, Farrell CA, Merenda JM, Conklyn MJ, Showell HJ.

Biochem Biophys Res Commun. 1991 May 31;177(1):192-201.


Evidence that peptidoleukotriene is a prerequisite for antigen-dependent thromboxane synthesis in IgG1-passively sensitized guinea pig lungs.

Cheng JB, Pillar JS, Conklyn MJ, Breslow R, Shirley JT, Showell HJ.

J Pharmacol Exp Ther. 1990 Nov;255(2):664-71.


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