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Items: 25


Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis.

Mizutani Y, Kobayashi H, Iida T, Asai N, Masamune A, Hara A, Esaki N, Ushida K, Mii S, Shiraki Y, Ando K, Weng L, Ishihara S, Ponik SM, Conklin MW, Haga H, Nagasaka A, Miyata T, Matsuyama M, Kobayashi T, Fujii T, Yamada S, Yamaguchi J, Wang T, Woods SL, Worthley D, Shimamura T, Fujishiro M, Hirooka Y, Enomoto A, Takahashi M.

Cancer Res. 2019 Oct 15;79(20):5367-5381. doi: 10.1158/0008-5472.CAN-19-0454. Epub 2019 Aug 22.


Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma.

Tomko LA, Hill RC, Barrett A, Szulczewski JM, Conklin MW, Eliceiri KW, Keely PJ, Hansen KC, Ponik SM.

Sci Rep. 2018 Aug 28;8(1):12941. doi: 10.1038/s41598-018-31126-w.


The Presence of Cyclooxygenase 2, Tumor-Associated Macrophages, and Collagen Alignment as Prognostic Markers for Invasive Breast Carcinoma Patients.

Esbona K, Yi Y, Saha S, Yu M, Van Doorn RR, Conklin MW, Graham DS, Wisinski KB, Ponik SM, Eliceiri KW, Wilke LG, Keely PJ.

Am J Pathol. 2018 Mar;188(3):559-573. doi: 10.1016/j.ajpath.2017.10.025.


Collagen Alignment as a Predictor of Recurrence after Ductal Carcinoma In Situ.

Conklin MW, Gangnon RE, Sprague BL, Van Gemert L, Hampton JM, Eliceiri KW, Bredfeldt JS, Liu Y, Surachaicharn N, Newcomb PA, Friedl A, Keely PJ, Trentham-Dietz A.

Cancer Epidemiol Biomarkers Prev. 2018 Feb;27(2):138-145. doi: 10.1158/1055-9965.EPI-17-0720. Epub 2017 Nov 15.


Tumor mechanics and metabolic dysfunction.

Tung JC, Barnes JM, Desai SR, Sistrunk C, Conklin MW, Schedin P, Eliceiri KW, Keely PJ, Seewaldt VL, Weaver VM.

Free Radic Biol Med. 2015 Feb;79:269-80. doi: 10.1016/j.freeradbiomed.2014.11.020. Epub 2014 Dec 19. Review.


Automated quantification of aligned collagen for human breast carcinoma prognosis.

Bredfeldt JS, Liu Y, Conklin MW, Keely PJ, Mackie TR, Eliceiri KW.

J Pathol Inform. 2014 Aug 28;5(1):28. doi: 10.4103/2153-3539.139707. eCollection 2014.


Computational segmentation of collagen fibers from second-harmonic generation images of breast cancer.

Bredfeldt JS, Liu Y, Pehlke CA, Conklin MW, Szulczewski JM, Inman DR, Keely PJ, Nowak RD, Mackie TR, Eliceiri KW.

J Biomed Opt. 2014 Jan;19(1):16007. doi: 10.1117/1.JBO.19.1.016007.


A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys.

Pugh TD, Conklin MW, Evans TD, Polewski MA, Barbian HJ, Pass R, Anderson BD, Colman RJ, Eliceiri KW, Keely PJ, Weindruch R, Beasley TM, Anderson RM.

Aging Cell. 2013 Aug;12(4):672-81. doi: 10.1111/acel.12091. Epub 2013 May 27.


Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers.

Conklin MW, Keely PJ.

Cell Adh Migr. 2012 May-Jun;6(3):249-60. doi: 10.4161/cam.20567. Epub 2012 May 1. Review.


Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2.

Lyons TR, O'Brien J, Borges VF, Conklin MW, Keely PJ, Eliceiri KW, Marusyk A, Tan AC, Schedin P.

Nat Med. 2011 Aug 7;17(9):1109-15. doi: 10.1038/nm.2416.


Aligned collagen is a prognostic signature for survival in human breast carcinoma.

Conklin MW, Eickhoff JC, Riching KM, Pehlke CA, Eliceiri KW, Provenzano PP, Friedl A, Keely PJ.

Am J Pathol. 2011 Mar;178(3):1221-32. doi: 10.1016/j.ajpath.2010.11.076.


R-Ras regulates beta1-integrin trafficking via effects on membrane ruffling and endocytosis.

Conklin MW, Ada-Nguema A, Parsons M, Riching KM, Keely PJ.

BMC Cell Biol. 2010 Feb 18;11:14. doi: 10.1186/1471-2121-11-14.


Nonlinear optical microscopy and computational analysis of intrinsic signatures in breast cancer.

Rueden CT, Conklin MW, Provenzano PP, Keely PJ, Eliceiri KW.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:4077-80. doi: 10.1109/IEMBS.2009.5334523.


Fluorescence lifetime imaging of endogenous fluorophores in histopathology sections reveals differences between normal and tumor epithelium in carcinoma in situ of the breast.

Conklin MW, Provenzano PP, Eliceiri KW, Sullivan R, Keely PJ.

Cell Biochem Biophys. 2009;53(3):145-57. doi: 10.1007/s12013-009-9046-7.


Nonlinear optical imaging of cellular processes in breast cancer.

Provenzano PP, Eliceiri KW, Yan L, Ada-Nguema A, Conklin MW, Inman DR, Keely PJ.

Microsc Microanal. 2008 Dec;14(6):532-48. doi: 10.1017/S1431927608080884.


Investigating integrin regulation and signaling events in three-dimensional systems.

Keely PJ, Conklin MW, Gehler S, Ponik SM, Provenzano PP.

Methods Enzymol. 2007;426:27-45. Review.


Outside and in: development of neuronal excitability.

Spitzer NC, Kingston PA, Manning TJ, Conklin MW.

Curr Opin Neurobiol. 2002 Jun;12(3):315-23. Review.


Reduction in density of transverse tubules and L-type Ca(2+) channels in canine tachycardia-induced heart failure.

He J, Conklin MW, Foell JD, Wolff MR, Haworth RA, Coronado R, Kamp TJ.

Cardiovasc Res. 2001 Feb 1;49(2):298-307.


Comparison of Ca(2+) sparks produced independently by two ryanodine receptor isoforms (type 1 or type 3).

Conklin MW, Ahern CA, Vallejo P, Sorrentino V, Takeshima H, Coronado R.

Biophys J. 2000 Apr;78(4):1777-85.


Involvement of the carboxy-terminus region of the dihydropyridine receptor beta1a subunit in excitation-contraction coupling of skeletal muscle.

Beurg M, Ahern CA, Vallejo P, Conklin MW, Powers PA, Gregg RG, Coronado R.

Biophys J. 1999 Dec;77(6):2953-67.


Contribution of ryanodine receptor type 3 to Ca(2+) sparks in embryonic mouse skeletal muscle.

Conklin MW, Barone V, Sorrentino V, Coronado R.

Biophys J. 1999 Sep;77(3):1394-403.


Differential regulation of skeletal muscle L-type Ca2+ current and excitation-contraction coupling by the dihydropyridine receptor beta subunit.

Beurg M, Sukhareva M, Ahern CA, Conklin MW, Perez-Reyes E, Powers PA, Gregg RG, Coronado R.

Biophys J. 1999 Apr;76(4):1744-56.


Decreased calcium currents in motor nerve terminals of mice with Lambert-Eaton myasthenic syndrome.

Smith DO, Conklin MW, Jensen PJ, Atchison WD.

J Physiol. 1995 Aug 15;487(1):115-23.

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