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Items: 28


Efficacy of Oral Tenofovir Alafenamide/Emtricitabine Combination or Single-Agent Tenofovir Alafenamide Against Vaginal Simian Human Immunodeficiency Virus Infection in Macaques.

Massud I, Cong ME, Ruone S, Holder A, Dinh C, Nishiura K, Khalil G, Pan Y, Lipscomb J, Johnson R, Deyounks F, Rooney JF, Babusis D, Park Y, McCallister S, Callebaut C, Heneine W, García-Lerma JG.

J Infect Dis. 2019 Oct 22;220(11):1826-1833. doi: 10.1093/infdis/jiz383.


Drug resistance emergence in macaques administered cabotegravir long-acting for pre-exposure prophylaxis during acute SHIV infection.

Radzio-Basu J, Council O, Cong ME, Ruone S, Newton A, Wei X, Mitchell J, Ellis S, Petropoulos CJ, Huang W, Spreen W, Heneine W, García-Lerma JG.

Nat Commun. 2019 May 1;10(1):2005. doi: 10.1038/s41467-019-10047-w.


On the Death Rate of Abortively Infected Cells: Estimation from Simian-Human Immunodeficiency Virus Infection.

Ke R, Cong ME, Li D, García-Lerma JG, Perelson AS.

J Virol. 2017 Aug 24;91(18). pii: e00352-17. doi: 10.1128/JVI.00352-17. Print 2017 Sep 15.


Antiretroviral Drug Activity in Macaques Infected during Pre-Exposure Prophylaxis Has a Transient Effect on Cell-Associated SHIV DNA Reservoirs.

Cong ME, Pau CP, Heneine W, García-Lerma JG.

PLoS One. 2016 Nov 2;11(11):e0164821. doi: 10.1371/journal.pone.0164821. eCollection 2016.


Efficacy of topical tenofovir against transmission of a tenofovir-resistant SHIV in macaques.

Dobard CW, Sharma S, Cong ME, West R, Makarova N, Holder A, Pau CP, Hanson DL, Novembre FJ, Garcia-Lerma JG, Heneine W.

Retrovirology. 2015 Aug 8;12:69. doi: 10.1186/s12977-015-0195-z.


Prophylactic efficacy of oral emtricitabine and tenofovir disoproxil fumarate combination therapy against a tenofovir-resistant simian/human immunodeficiency virus containing the K65R mutation in macaques.

Cong ME, Mitchell J, Sweeney E, Bachman S, Hanson DL, Heneine W, García-Lerma JG.

J Infect Dis. 2013 Aug 1;208(3):463-7. doi: 10.1093/infdis/jit189. Epub 2013 Apr 30.


Reduced inflammation and CD4 loss in acute SHIV infection during oral pre-exposure prophylaxis.

Kersh EN, Luo W, Zheng Q, Adams DR, Hanson D, Youngpairoj AS, Cong ME, Butler K, Hendry RM, McNicholl JM, Heneine W, Garcia-Lerma JG.

J Infect Dis. 2012 Sep 1;206(5):770-9. doi: 10.1093/infdis/jis422. Epub 2012 Jun 27.


Delayed maturation of antibody avidity but not seroconversion in rhesus macaques infected with simian HIV during oral pre-exposure prophylaxis.

Curtis KA, Kennedy MS, Luckay A, Cong ME, Youngpairoj AS, Zheng Q, Smith J, Hanson D, Heneine W, Owen SM, García-Lerma JG.

J Acquir Immune Defic Syndr. 2011 Aug 15;57(5):355-62. doi: 10.1097/QAI.0b013e3182234a51.


Protection against rectal transmission of an emtricitabine-resistant simian/human immunodeficiency virus SHIV162p3M184V mutant by intermittent prophylaxis with Truvada.

Cong ME, Youngpairoj AS, Zheng Q, Aung W, Mitchell J, Sweeney E, Hanson DL, Hendry RM, Dobard C, Heneine W, García-Lerma JG.

J Virol. 2011 Aug;85(15):7933-6. doi: 10.1128/JVI.00843-11. Epub 2011 Jun 1.


T cell chemo-vaccination effects after repeated mucosal SHIV exposures and oral pre-exposure prophylaxis.

Kersh EN, Adams DR, Youngpairoj AS, Luo W, Zheng Q, Cong ME, Aung W, Mitchell J, Otten R, Hendry RM, Heneine W, McNicholl J, Garcia-Lerma JG.

PLoS One. 2011 Apr 26;6(4):e19295. doi: 10.1371/journal.pone.0019295.


Natural substrate concentrations can modulate the prophylactic efficacy of nucleotide HIV reverse transcriptase inhibitors.

García-Lerma JG, Aung W, Cong ME, Zheng Q, Youngpairoj AS, Mitchell J, Holder A, Martin A, Kuklenyik S, Luo W, Lin CY, Hanson DL, Kersh E, Pau CP, Ray AS, Rooney JF, Lee WA, Heneine W.

J Virol. 2011 Jul;85(13):6610-7. doi: 10.1128/JVI.00311-11. Epub 2011 Apr 27.


Generation and mucosal transmissibility of emtricitabine- and tenofovir-resistant SHIV162P3 mutants in macaques.

Cong ME, Youngpairoj AS, Aung W, Sharma S, Mitchell J, Dobard C, Heneine W, Garcia-Lerma JG.

Virology. 2011 Apr 10;412(2):435-40. doi: 10.1016/j.virol.2011.01.038. Epub 2011 Feb 21.


Intermittent prophylaxis with oral truvada protects macaques from rectal SHIV infection.

García-Lerma JG, Cong ME, Mitchell J, Youngpairoj AS, Zheng Q, Masciotra S, Martin A, Kuklenyik Z, Holder A, Lipscomb J, Pau CP, Barr JR, Hanson DL, Otten R, Paxton L, Folks TM, Heneine W.

Sci Transl Med. 2010 Jan 13;2(14):14ra4. doi: 10.1126/scitranslmed.3000391.


On-line coupling of anion exchange and ion-pair chromatography for measurement of intracellular triphosphate metabolites of reverse transcriptase inhibitors.

Kuklenyik Z, Martin A, Pau CP, Holder A, Youngpairoj AS, Zheng Q, Cong ME, Garcia-Lerma JG, Heneine W, Pirkle JL, Barr JR.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Nov 1;877(29):3659-66. doi: 10.1016/j.jchromb.2009.09.007. Epub 2009 Sep 11.


Complete protection from repeated vaginal simian-human immunodeficiency virus exposures in macaques by a topical gel containing tenofovir alone or with emtricitabine.

Parikh UM, Dobard C, Sharma S, Cong ME, Jia H, Martin A, Pau CP, Hanson DL, Guenthner P, Smith J, Kersh E, Garcia-Lerma JG, Novembre FJ, Otten R, Folks T, Heneine W.

J Virol. 2009 Oct;83(20):10358-65. doi: 10.1128/JVI.01073-09. Epub 2009 Aug 5.


Prevention of rectal SHIV transmission in macaques by daily or intermittent prophylaxis with emtricitabine and tenofovir.

García-Lerma JG, Otten RA, Qari SH, Jackson E, Cong ME, Masciotra S, Luo W, Kim C, Adams DR, Monsour M, Lipscomb J, Johnson JA, Delinsky D, Schinazi RF, Janssen R, Folks TM, Heneine W.

PLoS Med. 2008 Feb;5(2):e28. doi: 10.1371/journal.pmed.0050028.


Clinical and virological characterization of persistent human infection with simian foamy viruses.

Boneva RS, Switzer WM, Spira TJ, Bhullar VB, Shanmugam V, Cong ME, Lam L, Heneine W, Folks TM, Chapman LE.

AIDS Res Hum Retroviruses. 2007 Nov;23(11):1330-7. doi: 10.1089/aid.2007.0104.


Simple PCR assays improve the sensitivity of HIV-1 subtype B drug resistance testing and allow linking of resistance mutations.

Johnson JA, Li JF, Wei X, Lipscomb J, Bennett D, Brant A, Cong ME, Spira T, Shafer RW, Heneine W.

PLoS One. 2007 Jul 25;2(7):e638.


Natural resistance of human immunodeficiency virus type 2 to zidovudine.

Reid P, MacInnes H, Cong ME, Heneine W, García-Lerma JG.

Virology. 2005 Jun 5;336(2):251-64.


Ancient co-speciation of simian foamy viruses and primates.

Switzer WM, Salemi M, Shanmugam V, Gao F, Cong ME, Kuiken C, Bhullar V, Beer BE, Vallet D, Gautier-Hion A, Tooze Z, Villinger F, Holmes EC, Heneine W.

Nature. 2005 Mar 17;434(7031):376-80.


Frequent simian foamy virus infection in persons occupationally exposed to nonhuman primates.

Switzer WM, Bhullar V, Shanmugam V, Cong ME, Parekh B, Lerche NW, Yee JL, Ely JJ, Boneva R, Chapman LE, Folks TM, Heneine W.

J Virol. 2004 Mar;78(6):2780-9.


Related TT viruses in chimpanzees.

Cong ME, Nichols B, Dou XG, Spelbring JE, Krawczynski K, Fields HA, Khudyakov YE.

Virology. 2000 Sep 1;274(2):343-55.


Sequence heterogeneity of TT virus and closely related viruses.

Khudyakov YE, Cong ME, Nichols B, Reed D, Dou XG, Viazov SO, Chang J, Fried MW, Williams I, Bower W, Lambert S, Purdy M, Roggendorf M, Fields HA.

J Virol. 2000 Apr;74(7):2990-3000.


Hepatitis G virus infection in Amerindians and other Venezuelan high-risk groups.

Pujol FH, Khudyakov YE, Devesa M, Cong ME, Loureiro CL, Blitz L, Capriles F, Beker S, Liprandi F, Fields HA.

J Clin Microbiol. 1998 Feb;36(2):470-4.


Sequence variation within a nonstructural region of the hepatitis G virus genome.

Khudyakov YE, Cong ME, Bonafonte MT, Abdulmalek S, Nichols BL, Lambert S, Alter MJ, Fields HA.

J Virol. 1997 Sep;71(9):6875-80.


Artificial mosaic proteins as new immunodiagnostic reagents: the hepatitis E virus experience.

Fields HA, Khudyakov YE, Favorov MO, Khudyakova NS, Cong ME, Holloway BF, Lambert SB, Jue DL.

Clin Diagn Virol. 1996 May;5(2-3):167-79.


Artificial mosaic protein containing antigenic epitopes of hepatitis E virus.

Khudyakov YE, Favorov MO, Khudyakova NS, Cong ME, Holloway BP, Padhye N, Lambert SB, Jue DL, Fields HA.

J Virol. 1994 Nov;68(11):7067-74.

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