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Combining nerve and tendon transfers in tetraplegia: a proposal of a new surgical strategy based on literature review.

Titolo P, Fusini F, Arrigoni C, Isoardo G, Conforti L, Artiaco S, Ciclamini D, Sicari M, Battiston B.

Eur J Orthop Surg Traumatol. 2019 Apr;29(3):521-530. doi: 10.1007/s00590-018-2352-2. Epub 2018 Dec 12.


A defect in KCa3.1 channel activity limits the ability of CD8+ T cells from cancer patients to infiltrate an adenosine-rich microenvironment.

Chimote AA, Balajthy A, Arnold MJ, Newton HS, Hajdu P, Qualtieri J, Wise-Draper T, Conforti L.

Sci Signal. 2018 Apr 24;11(527). pii: eaaq1616. doi: 10.1126/scisignal.aaq1616.


NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy.

Rossi F, Geiszler PC, Meng W, Barron MR, Prior M, Herd-Smith A, Loreto A, Lopez MY, Faas H, Pardon MC, Conforti L.

Behav Brain Res. 2018 Feb 26;339:140-152. doi: 10.1016/j.bbr.2017.11.030. Epub 2017 Nov 23.


Competency Crosswalk: A Multispecialty Review of the Accreditation Council for Graduate Medical Education Milestones Across Four Competency Domains.

Edgar L, Roberts S, Yaghmour NA, Leep Hunderfund A, Hamstra SJ, Conforti L, Holmboe ES.

Acad Med. 2018 Jul;93(7):1035-1041. doi: 10.1097/ACM.0000000000002059.


The Effect and Use of Milestones in the Assessment of Neurological Surgery Residents and Residency Programs.

Conforti LN, Yaghmour NA, Hamstra SJ, Holmboe ES, Kennedy B, Liu JJ, Waldo H, Selden NR.

J Surg Educ. 2018 Jan - Feb;75(1):147-155. doi: 10.1016/j.jsurg.2017.06.001. Epub 2017 Jun 22.


NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo.

Di Stefano M, Loreto A, Orsomando G, Mori V, Zamporlini F, Hulse RP, Webster J, Donaldson LF, Gering M, Raffaelli N, Coleman MP, Gilley J, Conforti L.

Curr Biol. 2017 Mar 20;27(6):784-794. doi: 10.1016/j.cub.2017.01.070. Epub 2017 Mar 2.


Potassium channels of T lymphocytes take center stage in the fight against cancer.

Conforti L.

J Immunother Cancer. 2017 Jan 17;5:2. doi: 10.1186/s40425-016-0202-5. eCollection 2017.


Kv1.3 Channels Mark Functionally Competent CD8+ Tumor-Infiltrating Lymphocytes in Head and Neck Cancer.

Chimote AA, Hajdu P, Sfyris AM, Gleich BN, Wise-Draper T, Casper KA, Conforti L.

Cancer Res. 2017 Jan 1;77(1):53-61. doi: 10.1158/0008-5472.CAN-16-2372. Epub 2016 Nov 4.


Commitment to Change and Challenges to Implementing Changes After Workplace-Based Assessment Rater Training.

Kogan JR, Conforti LN, Yamazaki K, Iobst W, Holmboe ES.

Acad Med. 2017 Mar;92(3):394-402. doi: 10.1097/ACM.0000000000001319.


Nanovesicle-targeted Kv1.3 knockdown in memory T cells suppresses CD40L expression and memory phenotype.

Chimote AA, Hajdu P, Kottyan LC, Harley JB, Yun Y, Conforti L.

J Autoimmun. 2016 May;69:86-93. doi: 10.1016/j.jaut.2016.03.004. Epub 2016 Mar 16.


Topical Application of a Galenical Formulation for the Management of Everolimus-Induced Mucositis in Patients with Metastatic Cancer: a Retrospective Study.

Conforti S, Minardi S, Conforti L, Turano S, Bilotta S, Vilardo E, Palazzo S.

Oncol Ther. 2016;4(2):275-286. doi: 10.1007/s40487-016-0032-0. Epub 2016 Oct 7.


Wallerian Degeneration Is Executed by an NMN-SARM1-Dependent Late Ca(2+) Influx but Only Modestly Influenced by Mitochondria.

Loreto A, Di Stefano M, Gering M, Conforti L.

Cell Rep. 2015 Dec 22;13(11):2539-2552. doi: 10.1016/j.celrep.2015.11.032. Epub 2015 Dec 10.


Reflections on the First 2 Years of Milestone Implementation.

Holmboe ES, Yamazaki K, Edgar L, Conforti L, Yaghmour N, Miller RS, Hamstra SJ.

J Grad Med Educ. 2015 Sep;7(3):506-11. doi: 10.4300/JGME-07-03-43. No abstract available.


Do Faculty Benefit From Participating in a Standardized Patient Assessment as Part of Rater Training? A Qualitative Study.

Conforti LN, Ross KM, Holmboe ES, Kogan JR.

Acad Med. 2016 Feb;91(2):262-71. doi: 10.1097/ACM.0000000000000838.


How faculty members experience workplace-based assessment rater training: a qualitative study.

Kogan JR, Conforti LN, Bernabeo E, Iobst W, Holmboe E.

Med Educ. 2015 Jul;49(7):692-708. doi: 10.1111/medu.12733.


Assessment and evaluation in interprofessional education: exploring the field.

Blue AV, Chesluk BJ, Conforti LN, Holmboe ES.

J Allied Health. 2015 Summer;44(2):73-82.


The C-terminus SH3-binding domain of Kv1.3 is required for the actin-mediated immobilization of the channel via cortactin.

Hajdu P, Martin GV, Chimote AA, Szilagyi O, Takimoto K, Conforti L.

Mol Biol Cell. 2015 May 1;26(9):1640-51. doi: 10.1091/mbc.E14-07-1195. Epub 2015 Mar 4.


Targeted therapy in renal carcinoma: a case of long-term effect with complete control of toxicity.

Conforti S, Ceniti S, Conforti L, Turano S, Minardi S, Palazzo S.

Tumori. 2014 Nov-Dec;100(6):e293-7. doi: 10.1700/1778.19302.


Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues.

Mori V, Amici A, Mazzola F, Di Stefano M, Conforti L, Magni G, Ruggieri S, Raffaelli N, Orsomando G.

PLoS One. 2014 Nov 25;9(11):e113939. doi: 10.1371/journal.pone.0113939. eCollection 2014.


A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration.

Di Stefano M, Nascimento-Ferreira I, Orsomando G, Mori V, Gilley J, Brown R, Janeckova L, Vargas ME, Worrell LA, Loreto A, Tickle J, Patrick J, Webster JR, Marangoni M, Carpi FM, Pucciarelli S, Rossi F, Meng W, Sagasti A, Ribchester RR, Magni G, Coleman MP, Conforti L.

Cell Death Differ. 2015 May;22(5):731-42. doi: 10.1038/cdd.2014.164. Epub 2014 Oct 17.


Age-related axonal swellings precede other neuropathological hallmarks in a knock-in mouse model of Huntington's disease.

Marangoni M, Adalbert R, Janeckova L, Patrick J, Kohli J, Coleman MP, Conforti L.

Neurobiol Aging. 2014 Oct;35(10):2382-93. doi: 10.1016/j.neurobiolaging.2014.04.024. Epub 2014 May 9.


Wallerian degeneration: an emerging axon death pathway linking injury and disease.

Conforti L, Gilley J, Coleman MP.

Nat Rev Neurosci. 2014 Jun;15(6):394-409. doi: 10.1038/nrn3680. Review.


Reconceptualizing variable rater assessments as both an educational and clinical care problem.

Kogan JR, Conforti LN, Iobst WF, Holmboe ES.

Acad Med. 2014 May;89(5):721-7. doi: 10.1097/ACM.0000000000000221. Review.


Early feedback on the use of the internal medicine reporting milestones in assessment of resident performance.

Aagaard E, Kane GC, Conforti L, Hood S, Caverzagie KJ, Smith C, Chick DA, Holmboe ES, Iobst WF.

J Grad Med Educ. 2013 Sep;5(3):433-8. doi: 10.4300/JGME-D-13-00001.1.


Development of an instrument to evaluate residents' confidence in quality improvement.

Hess BJ, Johnston MM, Lynn LA, Conforti LN, Holmboe ES.

Jt Comm J Qual Patient Saf. 2013 Nov;39(11):502-10.


Selective inhibition of KCa3.1 channels mediates adenosine regulation of the motility of human T cells.

Chimote AA, Hajdu P, Kucher V, Boiko N, Kuras Z, Szilagyi O, Yun YH, Conforti L.

J Immunol. 2013 Dec 15;191(12):6273-80. doi: 10.4049/jimmunol.1300702. Epub 2013 Nov 13.


Improvement of quality of life in third-line chemotherapy with lapatinib in a case of metastatic breast cancer.

Conforti S, Turano S, Minardi S, Locco C, Conforti L, Palazzo S.

Tumori. 2013 May-Jun;99(3):e136-9. doi: 10.1700/1334.14824.


Functionalized liposomes loaded with siRNAs targeting ion channels in effector memory T cells as a potential therapy for autoimmunity.

Hajdu P, Chimote AA, Thompson TH, Koo Y, Yun Y, Conforti L.

Biomaterials. 2013 Dec;34(38):10249-57. doi: 10.1016/j.biomaterials.2013.09.019. Epub 2013 Sep 27.


Diversification of NAD biological role: the importance of location.

Di Stefano M, Conforti L.

FEBS J. 2013 Oct;280(19):4711-28. doi: 10.1111/febs.12433. Epub 2013 Aug 1. Review.


Variability in obtaining institutional review board approval for quality improvement activities in residency programs.

Conforti LN, Hess BJ, Ross KM, Lynn LA, Holmboe ES.

J Grad Med Educ. 2012 Mar;4(1):106-8. doi: 10.4300/JGME-D-11-00176.1.


Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues.

Orsomando G, Cialabrini L, Amici A, Mazzola F, Ruggieri S, Conforti L, Janeckova L, Coleman MP, Magni G.

PLoS One. 2012;7(12):e53271. doi: 10.1371/journal.pone.0053271. Epub 2012 Dec 31.


Intra-axonal calcium changes after axotomy in wild-type and slow Wallerian degeneration axons.

Adalbert R, Morreale G, Paizs M, Conforti L, Walker SA, Roderick HL, Bootman MD, Siklós L, Coleman MP.

Neuroscience. 2012 Dec 6;225:44-54. doi: 10.1016/j.neuroscience.2012.08.056. Epub 2012 Sep 7.


KCa3.1 and TRPM7 channels at the uropod regulate migration of activated human T cells.

Kuras Z, Yun YH, Chimote AA, Neumeier L, Conforti L.

PLoS One. 2012;7(8):e43859. doi: 10.1371/journal.pone.0043859. Epub 2012 Aug 27.


Axonopathy in Huntington's disease.

Li JY, Conforti L.

Exp Neurol. 2013 Aug;246:62-71. doi: 10.1016/j.expneurol.2012.08.010. Epub 2012 Aug 19. Review.


dSarm/Sarm1 is required for activation of an injury-induced axon death pathway.

Osterloh JM, Yang J, Rooney TM, Fox AN, Adalbert R, Powell EH, Sheehan AE, Avery MA, Hackett R, Logan MA, MacDonald JM, Ziegenfuss JS, Milde S, Hou YJ, Nathan C, Ding A, Brown RH Jr, Conforti L, Coleman M, Tessier-Lavigne M, Züchner S, Freeman MR.

Science. 2012 Jul 27;337(6093):481-4. doi: 10.1126/science.1223899. Epub 2012 Jun 7.


Comparative trial of a web-based tool to improve the quality of care provided to older adults in residency clinics: modest success and a tough road ahead.

Holmboe ES, Hess BJ, Conforti LN, Lynn LA.

Acad Med. 2012 May;87(5):627-34. doi: 10.1097/ACM.0b013e31824cecb3.


The role of aspartic acid residues 405 and 416 of the kidney isotype of sodium-bicarbonate cotransporter 1 in its targeting to the plasma membrane.

Li HC, Kucher V, Li EY, Conforti L, Zahedi KA, Soleimani M.

Am J Physiol Cell Physiol. 2012 Jun 15;302(12):C1713-30. doi: 10.1152/ajpcell.00147.2011. Epub 2012 Mar 21.


Modulation of Kv1.3 channels by protein kinase A I in T lymphocytes is mediated by the disc large 1-tyrosine kinase Lck complex.

Kuras Z, Kucher V, Gordon SM, Neumeier L, Chimote AA, Filipovich AH, Conforti L.

Am J Physiol Cell Physiol. 2012 May 15;302(10):C1504-12. doi: 10.1152/ajpcell.00263.2011. Epub 2012 Feb 29.


Modulation of T cell activation by localized K⁺ accumulation at the immunological synapse--a mathematical model.

Martin GV, Yun Y, Conforti L.

J Theor Biol. 2012 May 7;300:173-82. doi: 10.1016/j.jtbi.2012.01.018. Epub 2012 Jan 23.


Faculty staff perceptions of feedback to residents after direct observation of clinical skills.

Kogan JR, Conforti LN, Bernabeo EC, Durning SJ, Hauer KE, Holmboe ES.

Med Educ. 2012 Feb;46(2):201-15. doi: 10.1111/j.1365-2923.2011.04137.x.


The ion channel network in T lymphocytes, a target for immunotherapy.

Conforti L.

Clin Immunol. 2012 Feb;142(2):105-6. doi: 10.1016/j.clim.2011.11.009. Epub 2011 Dec 2. No abstract available.


Disruption of kv1.3 channel forward vesicular trafficking by hypoxia in human T lymphocytes.

Chimote AA, Kuras Z, Conforti L.

J Biol Chem. 2012 Jan 13;287(3):2055-67. doi: 10.1074/jbc.M111.274209. Epub 2011 Nov 30.


Opening the black box of clinical skills assessment via observation: a conceptual model.

Kogan JR, Conforti L, Bernabeo E, Iobst W, Holmboe E.

Med Educ. 2011 Oct;45(10):1048-60. doi: 10.1111/j.1365-2923.2011.04025.x.


Lack of activation of renal functional reserve predicts the risk of significant renal involvement in systemic sclerosis.

Livi R, Guiducci S, Perfetto F, Ciuti G, Grifoni E, Conforti L, Galluccio F, Moggi Pignone A, Matucci Cerinic M.

Ann Rheum Dis. 2011 Nov;70(11):1963-7. doi: 10.1136/ard.2011.152892. Epub 2011 Jul 21.


Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration.

Conforti L, Janeckova L, Wagner D, Mazzola F, Cialabrini L, Di Stefano M, Orsomando G, Magni G, Bendotti C, Smyth N, Coleman M.

FEBS J. 2011 Aug;278(15):2666-79. doi: 10.1111/j.1742-4658.2011.08193.x. Epub 2011 Jun 14.


Listening to older adults: elderly patients' experience of care in residency and practicing physician outpatient clinics.

Hess BJ, Lynn LA, Conforti LN, Holmboe ES.

J Am Geriatr Soc. 2011 May;59(5):909-15. doi: 10.1111/j.1532-5415.2011.03370.x. Epub 2011 Apr 21.


Experimental and clinical employment of end-to-side coaptation: our experience.

Tos P, Geuna S, Papalia I, Conforti LG, Artiaco S, Battiston B.

Acta Neurochir Suppl. 2011;108:241-5. doi: 10.1007/978-3-211-99370-5_37.


What drives faculty ratings of residents' clinical skills? The impact of faculty's own clinical skills.

Kogan JR, Hess BJ, Conforti LN, Holmboe ES.

Acad Med. 2010 Oct;85(10 Suppl):S25-8. doi: 10.1097/ACM.0b013e3181ed1aa3.


Limits of reconstruction in mangled hands.

Tos P, Artiaco S, Titolo P, Conforti LG, Battiston B.

Chir Main. 2010 Sep;29(4):280-2. doi: 10.1016/j.main.2010.07.001. Epub 2010 Jul 24. No abstract available.


WldS can delay Wallerian degeneration in mice when interaction with valosin-containing protein is weakened.

Beirowski B, Morreale G, Conforti L, Mazzola F, Di Stefano M, Wilbrey A, Babetto E, Janeckova L, Magni G, Coleman MP.

Neuroscience. 2010 Mar 10;166(1):201-11. doi: 10.1016/j.neuroscience.2009.12.024. Epub 2009 Dec 16.


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