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Hyaluronan derivative HYMOVIS® increases cartilage volume and type ii collagen turnover in osteoarhritic knee: data from MOKHA study.

Henrotin Y, Bannuru R, Malaise M, Ea HK, Confavreux C, Bentin J, Urbin-Choffray D, Conrozier T, Brasseur JP, Thomas P, Hick AC, Marinello A, Giordan N, Richette P.

BMC Musculoskelet Disord. 2019 Jun 18;20(1):293. doi: 10.1186/s12891-019-2667-0.


Bone health in childhood cancer: review of the literature and recommendations for the management of bone health in childhood cancer survivors.

Marcucci G, Beltrami G, Tamburini A, Body JJ, Confavreux CB, Hadji P, Holzer G, Kendler D, Napoli N, Pierroz DD, Rizzoli R, Brandi ML.

Ann Oncol. 2019 May 21. pii: mdz120. doi: 10.1093/annonc/mdz120. [Epub ahead of print]


[Pharmaceutical interviews for rheumatoid arthritis patients: Perceptions and expectations of community pharmacists].

Yailian AL, Estublier C, Rozaire O, Piperno M, Confavreux C, Vignot E, Chapurlat R, Pivot C, Janoly-Dumenil A.

Ann Pharm Fr. 2019 Mar;77(2):146-158. doi: 10.1016/j.pharma.2018.10.003. Epub 2018 Dec 21. French.


Impact of bisphosphonate compliance on the risk of osteoporotic fracture in France.

Belhassen M, Cortet B, Confavreux CB, Lamezec L, Ginoux M, Van Ganse E.

Arch Osteoporos. 2018 Oct 19;13(1):113. doi: 10.1007/s11657-018-0530-9.


French recommendations for osteoporosis prevention and treatment in patients with prostate cancer treated by androgen deprivation.

Briot K, Paccou J, Beuzeboc P, Bonneterre J, Bouvard B, Confavreux CB, Cormier C, Cortet B, Hannoun-Lévi JM, Hennequin C, Javier RM, Lespessailles E, Mayeur D, Mongiat Artus P, Vieillard MH, Debiais F.

Joint Bone Spine. 2019 Jan;86(1):21-28. doi: 10.1016/j.jbspin.2018.09.017. Epub 2018 Oct 1.


Total Hip Arthroplasty for Periacetabular Metastatic Disease. An Original Technique of Reconstruction According to the Harrington Classification.

Wegrzyn J, Malatray M, Al-Qahtani T, Pibarot V, Confavreux C, Freyer G.

J Arthroplasty. 2018 Aug;33(8):2546-2555. doi: 10.1016/j.arth.2018.02.096. Epub 2018 Mar 17.


Bone metastases from lung cancer: A paradigm for multidisciplinary onco-rheumatology management.

Confavreux CB, Pialat JB, Bellière A, Brevet M, Decroisette C, Tescaru A, Wegrzyn J, Barrey C, Mornex F, Souquet PJ, Girard N.

Joint Bone Spine. 2019 Mar;86(2):185-194. doi: 10.1016/j.jbspin.2018.03.005. Epub 2018 Apr 6.


Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism.

Dirckx N, Tower RJ, Mercken EM, Vangoitsenhoven R, Moreau-Triby C, Breugelmans T, Nefyodova E, Cardoen R, Mathieu C, Van der Schueren B, Confavreux CB, Clemens TL, Maes C.

J Clin Invest. 2018 Mar 1;128(3):1087-1105. doi: 10.1172/JCI97794. Epub 2018 Feb 12.


Bone, muscle, and metabolic parameters predict survival in patients with synchronous bone metastases from lung cancers.

Chambard L, Girard N, Ollier E, Rousseau JC, Duboeuf F, Carlier MC, Brevet M, Szulc P, Pialat JB, Wegrzyn J, Clezardin P, Confavreux CB.

Bone. 2018 Mar;108:202-209. doi: 10.1016/j.bone.2018.01.004. Epub 2018 Jan 11.


Effect of intra-tibial injection on mechanical properties of mouse bone.

Delpuech B, Confavreux C, Bouazza L, Geraci S, Clezardin P, Mitton D, Follet H.

Comput Methods Biomech Biomed Engin. 2017 Oct;20(sup1):57-58. doi: 10.1080/10255842.2017.1382859. No abstract available.


Sclerostin and energy metabolism during physical activity.

Confavreux CB.

Calcif Tissue Int. 2018 Mar;102(3):382-383. doi: 10.1007/s00223-017-0341-9. Epub 2017 Oct 25. No abstract available.


The Relationship Between Body Composition and Bone Quality Measured with HR-pQCT in Peritoneal Dialysis Patients.

Fournie C, Pelletier S, Bacchetta J, Boutroy S, Confavreux C, Drai J, Arkouche W, Fouque D, Chapurlat R, Guebre-Egziabher F.

Perit Dial Int. 2017 Sep-Oct;37(5):548-555. doi: 10.3747/pdi.2016.00239. Epub 2017 Aug 1.


Management of psoriatic arthritis among cutaneous psoriasis patients: from pathogenesis to therapy.

Hoelt P, Confavreux C, Jullien D, Villani AP.

G Ital Dermatol Venereol. 2017 Oct;152(5):458-473. doi: 10.23736/S0392-0488.17.05680-2. Epub 2017 May 23. Review.


Serum Sclerostin Increases After Acute Physical Activity.

Pickering ME, Simon M, Sornay-Rendu E, Chikh K, Carlier MC, Raby AL, Szulc P, Confavreux CB.

Calcif Tissue Int. 2017 Aug;101(2):170-173. doi: 10.1007/s00223-017-0272-5. Epub 2017 Apr 3.


Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise.

Mera P, Laue K, Ferron M, Confavreux C, Wei J, Galán-Díez M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, de Cabo R, Friedman RA, Torsitano C, McGraw TE, Puchowicz M, Kurland I, Karsenty G.

Cell Metab. 2017 Jan 10;25(1):218. doi: 10.1016/j.cmet.2016.12.003. No abstract available.


Geographical Heterogeneity of Multiple Sclerosis Prevalence in France.

Pivot D, Debouverie M, Grzebyk M, Brassat D, Clanet M, Clavelou P, Confavreux C, Edan G, Leray E, Moreau T, Vukusic S, Hédelin G, Guillemin F.

PLoS One. 2016 Dec 9;11(12):e0167556. doi: 10.1371/journal.pone.0167556. eCollection 2016.


Risk of relapse after natalizumab withdrawal: Results from the French TYSEDMUS cohort.

Papeix C, Vukusic S, Casey R, Debard N, Stankoff B, Mrejen S, Uhry Z, Van Ganse E, Castot A, Clanet M, Lubetzki C, Confavreux C; TYSEDMUS and OFSEP Group.

Neurol Neuroimmunol Neuroinflamm. 2016 Oct 28;3(6):e297. eCollection 2016 Dec.


Anti-osteoporotic treatments in France: initiation, persistence and switches over 6 years of follow-up.

Belhassen M, Confavreux CB, Cortet B, Lamezec L, Ginoux M, Van Ganse E.

Osteoporos Int. 2017 Mar;28(3):853-862. doi: 10.1007/s00198-016-3789-y. Epub 2016 Oct 20.


History of multiple sclerosis in 2 successive pregnancies: A French and Italian cohort.

Benoit A, Durand-Dubief F, Amato MP, Portaccio E, Casey R, Roggerone S, Androdias G, Gignoux L, Ionescu I, Marrosu MG, Cocco E, Ghezzi A, Annovazzi P, Trojano M, Simone M, Marignier R, Confavreux C, Vukusic S.

Neurology. 2016 Sep 27;87(13):1360-7. doi: 10.1212/WNL.0000000000003036. Epub 2016 Jul 27.


Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise.

Mera P, Laue K, Ferron M, Confavreux C, Wei J, Galán-Díez M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, de Cabo R, Friedman RA, Torsitano C, McGraw TE, Puchowicz M, Kurland I, Karsenty G.

Cell Metab. 2016 Jun 14;23(6):1078-1092. doi: 10.1016/j.cmet.2016.05.004. Erratum in: Cell Metab. 2017 Jan 10;25(1):218.


Has sclerostin a true endocrine metabolic action complementary to osteocalcin in older men?

Confavreux CB, Casey R, Varennes A, Goudable J, Chapurlat RD, Szulc P.

Osteoporos Int. 2016 Jul;27(7):2301-2309. doi: 10.1007/s00198-016-3540-8. Epub 2016 Mar 23.


Novel biological markers of bone: from bone metabolism to bone physiology.

Chapurlat RD, Confavreux CB.

Rheumatology (Oxford). 2016 Oct;55(10):1714-25. doi: 10.1093/rheumatology/kev410. Epub 2016 Jan 20. Review.


Bone antiresorptive agents in the treatment of bone metastases associated with solid tumours or multiple myeloma.

Terpos E, Confavreux CB, Clézardin P.

Bonekey Rep. 2015 Oct 7;4:744. doi: 10.1038/bonekey.2015.113. eCollection 2015. Review.


A 10-year follow-up of the European multicenter trial of interferon β-1b in secondary-progressive multiple sclerosis.

Kuhle J, Hardmeier M, Disanto G, Gugleta K, Ecsedi M, Lienert C, Amato MP, Baum K, Buttmann M, Bayas A, Brassat D, Brochet B, Confavreux C, Edan G, Färkkilä M, Fredrikson S, Frontoni M, D'Hooghe M, Hutchinson M, De Keyser J, Kieseier BC, Kümpfel T, Rio J, Polman C, Roullet E, Stolz C, Vass K, Wandinger KP, Kappos L; European Long-term Follow-up Study Group in Interferon β-1b in Secondary-progressive Multiple Sclerosis.

Mult Scler. 2016 Apr;22(4):533-43. doi: 10.1177/1352458515594440. Epub 2015 Sep 11.


Excess Mortality in Patients with Multiple Sclerosis Starts at 20 Years from Clinical Onset: Data from a Large-Scale French Observational Study.

Leray E, Vukusic S, Debouverie M, Clanet M, Brochet B, de Sèze J, Zéphir H, Defer G, Lebrun-Frenay C, Moreau T, Clavelou P, Pelletier J, Berger E, Cabre P, Camdessanché JP, Kalson-Ray S, Confavreux C, Edan G.

PLoS One. 2015 Jul 6;10(7):e0132033. doi: 10.1371/journal.pone.0132033. eCollection 2015.


Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis.

Oury F, Ferron M, Huizhen W, Confavreux C, Xu L, Lacombe J, Srinivas P, Chamouni A, Lugani F, Lejeune H, Kumar TR, Plotton I, Karsenty G.

J Clin Invest. 2015 May;125(5):2180. doi: 10.1172/JCI81812. Epub 2015 May 1. No abstract available.


Serum sclerostin: the missing link in the bone-vessel cross-talk in hemodialysis patients?

Pelletier S, Confavreux CB, Haesebaert J, Guebre-Egziabher F, Bacchetta J, Carlier MC, Chardon L, Laville M, Chapurlat R, London GM, Lafage-Proust MH, Fouque D.

Osteoporos Int. 2015 Aug;26(8):2165-74. doi: 10.1007/s00198-015-3127-9. Epub 2015 Apr 25.


Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study.

Kuhle J, Disanto G, Dobson R, Adiutori R, Bianchi L, Topping J, Bestwick JP, Meier UC, Marta M, Dalla Costa G, Runia T, Evdoshenko E, Lazareva N, Thouvenot E, Iaffaldano P, Direnzo V, Khademi M, Piehl F, Comabella M, Sombekke M, Killestein J, Hegen H, Rauch S, D'Alfonso S, Alvarez-Cermeño JC, Kleinová P, Horáková D, Roesler R, Lauda F, Llufriu S, Avsar T, Uygunoglu U, Altintas A, Saip S, Menge T, Rajda C, Bergamaschi R, Moll N, Khalil M, Marignier R, Dujmovic I, Larsson H, Malmestrom C, Scarpini E, Fenoglio C, Wergeland S, Laroni A, Annibali V, Romano S, Martínez AD, Carra A, Salvetti M, Uccelli A, Torkildsen Ø, Myhr KM, Galimberti D, Rejdak K, Lycke J, Frederiksen JL, Drulovic J, Confavreux C, Brassat D, Enzinger C, Fuchs S, Bosca I, Pelletier J, Picard C, Colombo E, Franciotta D, Derfuss T, Lindberg R, Yaldizli Ö, Vécsei L, Kieseier BC, Hartung HP, Villoslada P, Siva A, Saiz A, Tumani H, Havrdová E, Villar LM, Leone M, Barizzone N, Deisenhammer F, Teunissen C, Montalban X, Tintoré M, Olsson T, Trojano M, Lehmann S, Castelnovo G, Lapin S, Hintzen R, Kappos L, Furlan R, Martinelli V, Comi G, Ramagopalan SV, Giovannoni G.

Mult Scler. 2015 Jul;21(8):1013-24. doi: 10.1177/1352458514568827. Epub 2015 Feb 13.


Mutational profiling of bone metastases from lung adenocarcinoma: results of a prospective study (POUMOS-TEC).

Confavreux CB, Girard N, Pialat JB, Bringuier PP, Devouassoux-Shisheboran M, Rousseau JC, Isaac S, Thivolet-Bejui F, Clezardin P, Brevet M.

Bonekey Rep. 2014 Oct 1;3:580. doi: 10.1038/bonekey.2014.75. eCollection 2014.


Natalizumab for the prevention of post-partum relapses in women with multiple sclerosis.

Vukusic S, Durand-Dubief F, Benoit A, Marignier R, Frangoulis B, Confavreux C.

Mult Scler. 2015 Jun;21(7):953-5. doi: 10.1177/1352458514554056. Epub 2014 Oct 10.


Tissue remodeling in periplaque regions of multiple sclerosis spinal cord lesions.

Lieury A, Chanal M, Androdias G, Reynolds R, Cavagna S, Giraudon P, Confavreux C, Nataf S.

Glia. 2014 Oct;62(10):1645-58. doi: 10.1002/glia.22705. Epub 2014 Jun 7.


Lower serum osteocalcin is associated with more severe metabolic syndrome in elderly men from the MINOS cohort.

Confavreux CB, Szulc P, Casey R, Varennes A, Goudable J, Chapurlat RD.

Eur J Endocrinol. 2014 Aug;171(2):275-83. doi: 10.1530/EJE-13-0567. Epub 2014 May 19.


Multiple sclerosis registries in Europe - results of a systematic survey.

Flachenecker P, Buckow K, Pugliatti M, Kes VB, Battaglia MA, Boyko A, Confavreux C, Ellenberger D, Eskic D, Ford D, Friede T, Fuge J, Glaser A, Hillert J, Holloway E, Ioannidou E, Kappos L, Kasilingam E, Koch-Henriksen N, Kuhle J, Lepore V, Middleton R, Myhr KM, Orologas A, Otero S, Pitschnau-Michel D, Rienhoff O, Sastre-Garriga J, Schyns-Liharska T, Sutovic D, Thalheim C, Trojano M, Vlasov YV, Yaldizli O; EUReMS Consortium.

Mult Scler. 2014 Oct;20(11):1523-32. doi: 10.1177/1352458514528760. Epub 2014 Apr 28.


[Cerebrotendinous xanthomatosis: a multicentric retrospective study of 15 adults, clinical and paraclinical typical and atypical aspects].

Lionnet C, Carra C, Ayrignac X, Levade T, Gayraud D, Castelnovo G, Besson G, Androdias G, Vukusic S, Confavreux C, Zaenker C, De Seze J, Collongues N, Blanc F, Tranchant C, Wallon D, Hannequin D, Gerdelat-Mas A, Brassat D, Clanet M, Zephir H, Outteryck O, Vermersch P, Labauge P.

Rev Neurol (Paris). 2014 Jun-Jul;170(6-7):445-53. doi: 10.1016/j.neurol.2014.01.675. Epub 2014 Apr 16. French.


[Sequential MRI imaging of progressive bilateral rostro-caudal medullary infarction].

Boulogne S, Roggerone S, Deiana G, Derex L, Vukusic S, Confavreux C, Nighoghossian N.

Rev Neurol (Paris). 2014 Apr;170(4):277-9. doi: 10.1016/j.neurol.2014.01.677. Epub 2014 Apr 13. French.


Combination of anti-angiogenic therapies reduces osteolysis and tumor burden in experimental breast cancer bone metastasis.

Bachelier R, Confavreux CB, Peyruchaud O, Croset M, Goehrig D, van der Pluijm G, Clézardin P.

Int J Cancer. 2014 Sep 15;135(6):1319-29. doi: 10.1002/ijc.28787. Epub 2014 Mar 3.


Paradoxical psoriatic arthritis in a patient with rheumatoid arthritis treated by TNFα blocker.

Villani AP, Weiler L, Jullien D, Chapurlat R, Confavreux C.

Joint Bone Spine. 2014 Oct;81(5):455-6. doi: 10.1016/j.jbspin.2014.01.004. Epub 2014 Feb 20. No abstract available.


The clinical course of multiple sclerosis.

Confavreux C, Vukusic S.

Handb Clin Neurol. 2014;122:343-69. doi: 10.1016/B978-0-444-52001-2.00014-5. Review.


Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): a randomised, double-blind, placebo-controlled, phase 3 trial.

Confavreux C, O'Connor P, Comi G, Freedman MS, Miller AE, Olsson TP, Wolinsky JS, Bagulho T, Delhay JL, Dukovic D, Truffinet P, Kappos L; TOWER Trial Group.

Lancet Neurol. 2014 Mar;13(3):247-56. doi: 10.1016/S1474-4422(13)70308-9. Epub 2014 Jan 23.


Etanercept may induce neurosarcoidosis in a patient treated for rheumatoid arthritis.

Durel CA, Feurer E, Pialat JB, Berthoux E, Chapurlat RD, Confavreux CB.

BMC Neurol. 2013 Dec 28;13:212. doi: 10.1186/1471-2377-13-212.


Characterization of neuromyelitis optica and neuromyelitis optica spectrum disorder patients with a late onset.

Collongues N, Marignier R, Jacob A, Leite MI, Siva A, Paul F, Zephir H, Akman-Demir G, Elsone L, Jarius S, Papeix C, Mutch K, Saip S, Wildemann B, Kitley J, Karabudak R, Aktas O, Kuscu D, Altintas A, Palace J, Confavreux C, De Seze J.

Mult Scler. 2014 Jul;20(8):1086-94. doi: 10.1177/1352458513515085. Epub 2013 Dec 9.


One can prevent post-partum MS relapses by exclusive breast feeding: no.

Vukusic S, Confavreux C.

Mult Scler. 2013 Oct;19(12):1565-6. doi: 10.1177/1352458513503054. No abstract available.


Teriflunomide versus subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis: a randomised, controlled phase 3 trial.

Vermersch P, Czlonkowska A, Grimaldi LM, Confavreux C, Comi G, Kappos L, Olsson TP, Benamor M, Bauer D, Truffinet P, Church M, Miller AE, Wolinsky JS, Freedman MS, O'Connor P; TENERE Trial Group.

Mult Scler. 2014 May;20(6):705-16. doi: 10.1177/1352458513507821. Epub 2013 Oct 14.


Teriflunomide reduces relapse-related neurological sequelae, hospitalizations and steroid use.

O'Connor PW, Lublin FD, Wolinsky JS, Confavreux C, Comi G, Freedman MS, Olsson TP, Miller AE, Dive-Pouletty C, Bégo-Le-Bagousse G, Kappos L.

J Neurol. 2013 Oct;260(10):2472-80. doi: 10.1007/s00415-013-6979-y. Epub 2013 Jul 14.


Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis.

Oury F, Ferron M, Huizhen W, Confavreux C, Xu L, Lacombe J, Srinivas P, Chamouni A, Lugani F, Lejeune H, Kumar TR, Plotton I, Karsenty G.

J Clin Invest. 2013 Jun;123(6):2421-33. Erratum in: J Clin Invest. 2015 May;125(5):2180.


Mycophenolate mofetil in multiple sclerosis: a multicentre retrospective study on 344 patients.

Michel L, Vukusic S, De Seze J, Ducray F, Ongagna JC, Lefrère F, Jacq-Foucher M, Confavreux C, Wiertlewski S, Laplaud DA.

J Neurol Neurosurg Psychiatry. 2014 Mar;85(3):279-83. doi: 10.1136/jnnp-2013-305298. Epub 2013 May 23.


Aquaporin-4 antibody-negative neuromyelitis optica: distinct assay sensitivity-dependent entity.

Marignier R, Bernard-Valnet R, Giraudon P, Collongues N, Papeix C, Zéphir H, Cavillon G, Rogemond V, Casey R, Frangoulis B, De Sèze J, Vukusic S, Honnorat J, Confavreux C; NOMADMUS Study Group.

Neurology. 2013 Jun 11;80(24):2194-200. doi: 10.1212/WNL.0b013e318296e917. Epub 2013 May 8.


Spontaneous odontoid fracture on a tophus responsible for spinal cord compression: a case report.

de Parisot A, Ltaief-Boudrigua A, Villani AP, Barrey C, Chapurlat RD, Confavreux CB.

Joint Bone Spine. 2013 Oct;80(5):550-1. doi: 10.1016/j.jbspin.2013.02.003. Epub 2013 Apr 6. No abstract available.


Persistent visual impairment in multiple sclerosis: prevalence, mechanisms and resulting disability.

Jasse L, Vukusic S, Durand-Dubief F, Vartin C, Piras C, Bernard M, Pélisson D, Confavreux C, Vighetto A, Tilikete C.

Mult Scler. 2013 Oct;19(12):1618-26. doi: 10.1177/1352458513479840. Epub 2013 Mar 5.


Magnetic resonance imaging outcomes from a phase III trial of teriflunomide.

Wolinsky JS, Narayana PA, Nelson F, Datta S, O'Connor P, Confavreux C, Comi G, Kappos L, Olsson TP, Truffinet P, Wang L, Miller A, Freedman MS; Teriflunomide Multiple Sclerosis Oral (TEMSO) Trial Group.

Mult Scler. 2013 Sep;19(10):1310-9. doi: 10.1177/1352458513475723. Epub 2013 Feb 27.


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