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Items: 5

1.

Reproducing human and cross-species drug toxicities using a Liver-Chip.

Jang KJ, Otieno MA, Ronxhi J, Lim HK, Ewart L, Kodella KR, Petropolis DB, Kulkarni G, Rubins JE, Conegliano D, Nawroth J, Simic D, Lam W, Singer M, Barale E, Singh B, Sonee M, Streeter AJ, Manthey C, Jones B, Srivastava A, Andersson LC, Williams D, Park H, Barrile R, Sliz J, Herland A, Haney S, Karalis K, Ingber DE, Hamilton GA.

Sci Transl Med. 2019 Nov 6;11(517). pii: eaax5516. doi: 10.1126/scitranslmed.aax5516.

PMID:
31694927
2.

Stem cell-based Lung-on-Chips: The best of both worlds?

Nawroth JC, Barrile R, Conegliano D, van Riet S, Hiemstra PS, Villenave R.

Adv Drug Deliv Rev. 2019 Feb 1;140:12-32. doi: 10.1016/j.addr.2018.07.005. Epub 2018 Jul 25. Review.

PMID:
30009883
3.

Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems.

Barrile R, van der Meer AD, Park H, Fraser JP, Simic D, Teng F, Conegliano D, Nguyen J, Jain A, Zhou M, Karalis K, Ingber DE, Hamilton GA, Otieno MA.

Clin Pharmacol Ther. 2018 Dec;104(6):1240-1248. doi: 10.1002/cpt.1054. Epub 2018 Apr 30.

PMID:
29484632
4.

A microengineered model of RBC transfusion-induced pulmonary vascular injury.

Seo J, Conegliano D, Farrell M, Cho M, Ding X, Seykora T, Qing D, Mangalmurti NS, Huh D.

Sci Rep. 2017 Jun 13;7(1):3413. doi: 10.1038/s41598-017-03597-w.

5.

Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation.

Qing DY, Conegliano D, Shashaty MG, Seo J, Reilly JP, Worthen GS, Huh D, Meyer NJ, Mangalmurti NS.

Am J Respir Crit Care Med. 2014 Dec 1;190(11):1243-54. doi: 10.1164/rccm.201406-1095OC.

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