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Items: 1 to 50 of 127

1.

Myosin-IIA Heavy Chain Phosphorylation on S1943 Regulates Tumor Metastasis.

Norwood Toro LE, Wang Y, Condeelis JS, Jones JG, Backer J, Bresnick AR.

Exp Cell Res. 2018 Jun 25. pii: S0014-4827(18)30369-0. doi: 10.1016/j.yexcr.2018.06.028. [Epub ahead of print]

PMID:
29953877
2.

Targeting invadopodia-mediated breast cancer metastasis by using ABL kinase inhibitors.

Meirson T, Genna A, Lukic N, Makhnii T, Alter J, Sharma VP, Wang Y, Samson AO, Condeelis JS, Gil-Henn H.

Oncotarget. 2018 Apr 24;9(31):22158-22183. doi: 10.18632/oncotarget.25243. eCollection 2018 Apr 24.

3.

A Unidirectional Transition from Migratory to Perivascular Macrophage Is Required for Tumor Cell Intravasation.

Arwert EN, Harney AS, Entenberg D, Wang Y, Sahai E, Pollard JW, Condeelis JS.

Cell Rep. 2018 May 1;23(5):1239-1248. doi: 10.1016/j.celrep.2018.04.007.

4.

A novel neuregulin - jagged1 paracrine loop in breast cancer transendothelial migration.

Cabrera RM, Mao SPH, Surve CR, Condeelis JS, Segall JE.

Breast Cancer Res. 2018 Apr 10;20(1):24. doi: 10.1186/s13058-018-0960-8.

5.

Chemotherapy-induced metastasis in breast cancer.

Karagiannis GS, Condeelis JS, Oktay MH.

Oncotarget. 2017 Nov 27;8(67):110733-110734. doi: 10.18632/oncotarget.22717. eCollection 2017 Dec 19. No abstract available.

6.

Chemotherapy-induced metastasis: mechanisms and translational opportunities.

Karagiannis GS, Condeelis JS, Oktay MH.

Clin Exp Metastasis. 2018 Jan 6. doi: 10.1007/s10585-017-9870-x. [Epub ahead of print]

PMID:
29307118
7.

Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells.

Genna A, Lapetina S, Lukic N, Twafra S, Meirson T, Sharma VP, Condeelis JS, Gil-Henn H.

J Cell Biol. 2018 Jan 2;217(1):375-395. doi: 10.1083/jcb.201702184. Epub 2017 Nov 13.

8.

Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation.

Donnelly SK, Cabrera R, Mao SPH, Christin JR, Wu B, Guo W, Bravo-Cordero JJ, Condeelis JS, Segall JE, Hodgson L.

J Cell Biol. 2017 Dec 4;216(12):4331-4349. doi: 10.1083/jcb.201704048. Epub 2017 Oct 23.

9.

The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors.

Harney AS, Karagiannis GS, Pignatelli J, Smith BD, Kadioglu E, Wise SC, Hood MM, Kaufman MD, Leary CB, Lu WP, Al-Ani G, Chen X, Entenberg D, Oktay MH, Wang Y, Chun L, De Palma M, Jones JG, Flynn DL, Condeelis JS.

Mol Cancer Ther. 2017 Nov;16(11):2486-2501. doi: 10.1158/1535-7163.MCT-17-0241. Epub 2017 Aug 24.

PMID:
28838996
10.

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.

Karagiannis GS, Pastoriza JM, Wang Y, Harney AS, Entenberg D, Pignatelli J, Sharma VP, Xue EA, Cheng E, D'Alfonso TM, Jones JG, Anampa J, Rohan TE, Sparano JA, Condeelis JS, Oktay MH.

Sci Transl Med. 2017 Jul 5;9(397). pii: eaan0026. doi: 10.1126/scitranslmed.aan0026. Erratum in: Sci Transl Med. 2017 Jul 19;9(399):.

11.

Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis.

Eddy RJ, Weidmann MD, Sharma VP, Condeelis JS.

Trends Cell Biol. 2017 Aug;27(8):595-607. doi: 10.1016/j.tcb.2017.03.003. Epub 2017 Apr 12. Review.

PMID:
28412099
12.

Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation.

Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi SJ, Wang Y, Chen X, Eddy RJ, Xue A, Singer RH, Hodgson L, Oktay MH, Condeelis JS.

Sci Rep. 2016 Nov 30;6:37874. doi: 10.1038/srep37874.

13.

MenaINV dysregulates cortactin phosphorylation to promote invadopodium maturation.

Weidmann MD, Surve CR, Eddy RJ, Chen X, Gertler FB, Sharma VP, Condeelis JS.

Sci Rep. 2016 Nov 8;6:36142. doi: 10.1038/srep36142.

14.

Validation of a device for the active manipulation of the tumor microenvironment during intravital imaging.

Williams JK, Entenberg D, Wang Y, Avivar-Valderas A, Padgen M, Clark A, Aguirre-Ghiso JA, Castracane J, Condeelis JS.

Intravital. 2016;5(2). pii: e1182271. Epub 2016 Apr 29.

15.

Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window.

Rodriguez-Tirado C, Kitamura T, Kato Y, Pollard JW, Condeelis JS, Entenberg D.

J Vis Exp. 2016 Oct 6;(116). doi: 10.3791/54603.

16.

The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior.

Balsamo M, Mondal C, Carmona G, McClain LM, Riquelme DN, Tadros J, Ma D, Vasile E, Condeelis JS, Lauffenburger DA, Gertler FB.

Sci Rep. 2016 Oct 17;6:35298. doi: 10.1038/srep35298.

17.

Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells.

Morris BA, Burkel B, Ponik SM, Fan J, Condeelis JS, Aguirre-Ghiso JA, Castracane J, Denu JM, Keely PJ.

EBioMedicine. 2016 Nov;13:146-156. doi: 10.1016/j.ebiom.2016.10.012. Epub 2016 Oct 8.

18.

Extended Time-lapse Intravital Imaging of Real-time Multicellular Dynamics in the Tumor Microenvironment.

Harney AS, Wang Y, Condeelis JS, Entenberg D.

J Vis Exp. 2016 Jun 12;(112). doi: 10.3791/54042.

19.

Signatures of breast cancer metastasis at a glance.

Karagiannis GS, Goswami S, Jones JG, Oktay MH, Condeelis JS.

J Cell Sci. 2016 May 1;129(9):1751-8. doi: 10.1242/jcs.183129. Epub 2016 Apr 15. Review.

20.

GPCR Signaling Mediates Tumor Metastasis via PI3Kβ.

Khalil BD, Hsueh C, Cao Y, Abi Saab WF, Wang Y, Condeelis JS, Bresnick AR, Backer JM.

Cancer Res. 2016 May 15;76(10):2944-53. doi: 10.1158/0008-5472.CAN-15-1675. Epub 2016 Mar 24.

21.

3-D individual cell based computational modeling of tumor cell-macrophage paracrine signaling mediated by EGF and CSF-1 gradients.

Knutsdottir H, Condeelis JS, Palsson E.

Integr Biol (Camb). 2016 Jan;8(1):104-19. doi: 10.1039/c5ib00201j. Epub 2015 Dec 21.

22.

Characterization of the expression of the pro-metastatic Mena(INV) isoform during breast tumor progression.

Oudin MJ, Hughes SK, Rohani N, Moufarrej MN, Jones JG, Condeelis JS, Lauffenburger DA, Gertler FB.

Clin Exp Metastasis. 2016 Mar;33(3):249-61. doi: 10.1007/s10585-015-9775-5. Epub 2015 Dec 17.

23.

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.

Hughes SK, Oudin MJ, Tadros J, Neil J, Del Rosario A, Joughin BA, Ritsma L, Wyckoff J, Vasile E, Eddy R, Philippar U, Lussiez A, Condeelis JS, van Rheenen J, White F, Lauffenburger DA, Gertler FB.

Mol Biol Cell. 2015 Nov 1;26(21):3867-78. doi: 10.1091/mbc.E15-06-0442. Epub 2015 Sep 2.

24.

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA.

Harney AS, Arwert EN, Entenberg D, Wang Y, Guo P, Qian BZ, Oktay MH, Pollard JW, Jones JG, Condeelis JS.

Cancer Discov. 2015 Sep;5(9):932-43. doi: 10.1158/2159-8290.CD-15-0012. Epub 2015 Aug 12.

25.

Menacalc, a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer.

Forse CL, Agarwal S, Pinnaduwage D, Gertler F, Condeelis JS, Lin J, Xue X, Johung K, Mulligan AM, Rohan TE, Bull SB, Andrulis IL.

BMC Cancer. 2015 Jun 27;15:483. doi: 10.1186/s12885-015-1468-6.

26.

Profilin1 regulates invadopodium maturation in human breast cancer cells.

Valenzuela-Iglesias A, Sharma VP, Beaty BT, Ding Z, Gutierrez-Millan LE, Roy P, Condeelis JS, Bravo-Cordero JJ.

Eur J Cell Biol. 2015 Feb;94(2):78-89. doi: 10.1016/j.ejcb.2014.12.002. Epub 2014 Dec 31.

27.

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration.

Pignatelli J, Goswami S, Jones JG, Rohan TE, Pieri E, Chen X, Adler E, Cox D, Maleki S, Bresnick A, Gertler FB, Condeelis JS, Oktay MH.

Sci Signal. 2014 Nov 25;7(353):ra112. doi: 10.1126/scisignal.2005329.

28.

Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFβ in claudin-low breast tumor cells.

Patsialou A, Wang Y, Pignatelli J, Chen X, Entenberg D, Oktay M, Condeelis JS.

Oncogene. 2015 May 21;34(21):2721-31. doi: 10.1038/onc.2014.226. Epub 2014 Aug 4.

29.

An in vitro one-dimensional assay to study growth factor-regulated tumor cell-macrophage interaction.

Sharma VP, Beaty BT, Cox D, Condeelis JS, Eddy RJ.

Methods Mol Biol. 2014;1172:115-23. doi: 10.1007/978-1-4939-0928-5_10.

30.

Metastatic cells: moving onco-targets.

Patsialou A, Condeelis JS.

Oncotarget. 2014 Jun 15;5(11):3424-5. No abstract available.

31.

Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer.

Rohan TE, Xue X, Lin HM, D'Alfonso TM, Ginter PS, Oktay MH, Robinson BD, Ginsberg M, Gertler FB, Glass AG, Sparano JA, Condeelis JS, Jones JG.

J Natl Cancer Inst. 2014 Jun 3;106(8). pii: dju136. doi: 10.1093/jnci/dju136. Print 2014 Aug.

32.

Invadopodia in context.

Bergman A, Condeelis JS, Gligorijevic B.

Cell Adh Migr. 2014;8(3):273-9. Review.

33.

Spatial regulation of tumor cell protrusions by RhoC.

Bravo-Cordero JJ, Hodgson L, Condeelis JS.

Cell Adh Migr. 2014;8(3):263-7. Review.

34.

Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis.

Kwon M, Lee SJ, Wang Y, Rybak Y, Luna A, Reddy S, Adem A, Beaty BT, Condeelis JS, Libutti SK.

Int J Cancer. 2014 Jul 1;135(1):48-60. doi: 10.1002/ijc.28662. Epub 2014 Feb 20.

35.

Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo.

Zhou ZN, Sharma VP, Beaty BT, Roh-Johnson M, Peterson EA, Van Rooijen N, Kenny PA, Wiley HS, Condeelis JS, Segall JE.

Oncogene. 2014 Jul 17;33(29):3784-93. doi: 10.1038/onc.2013.363. Epub 2013 Sep 9.

36.

Wiskott-Aldrich syndrome protein regulates leukocyte-dependent breast cancer metastasis.

Ishihara D, Dovas A, Hernandez L, Pozzuto M, Wyckoff J, Segall JE, Condeelis JS, Bresnick AR, Cox D.

Cell Rep. 2013 Aug 15;4(3):429-36. doi: 10.1016/j.celrep.2013.07.007. Epub 2013 Aug 1.

37.

Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells.

Stadler SC, Vincent CT, Fedorov VD, Patsialou A, Cherrington BD, Wakshlag JJ, Mohanan S, Zee BM, Zhang X, Garcia BA, Condeelis JS, Brown AM, Coonrod SA, Allis CD.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11851-6. doi: 10.1073/pnas.1308362110. Epub 2013 Jul 1. Erratum in: Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16283.

38.

Intravital multiphoton imaging reveals multicellular streaming as a crucial component of in vivo cell migration in human breast tumors.

Patsialou A, Bravo-Cordero JJ, Wang Y, Entenberg D, Liu H, Clarke M, Condeelis JS.

Intravital. 2013 Apr 1;2(2):e25294.

39.

Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients.

Patsialou A, Wang Y, Lin J, Whitney K, Goswami S, Kenny PA, Condeelis JS.

Breast Cancer Res. 2012 Oct 31;14(5):R139. doi: 10.1186/bcr3344.

40.

Quantitative assessment of invasive mena isoforms (Menacalc) as an independent prognostic marker in breast cancer.

Agarwal S, Gertler FB, Balsamo M, Condeelis JS, Camp RL, Xue X, Lin J, Rohan TE, Rimm DL.

Breast Cancer Res. 2012 Sep 12;14(5):R124. doi: 10.1186/bcr3318.

41.

A FRET-facilitated photoswitching using an orange fluorescent protein with the fast photoconversion kinetics.

Subach OM, Entenberg D, Condeelis JS, Verkhusha VV.

J Am Chem Soc. 2012 Sep 12;134(36):14789-99. doi: 10.1021/ja3034137. Epub 2012 Aug 27.

42.

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function.

Zervantonakis IK, Hughes-Alford SK, Charest JL, Condeelis JS, Gertler FB, Kamm RD.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13515-20. doi: 10.1073/pnas.1210182109. Epub 2012 Aug 6.

43.

Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo.

Gil-Henn H, Patsialou A, Wang Y, Warren MS, Condeelis JS, Koleske AJ.

Oncogene. 2013 May 23;32(21):2622-30. doi: 10.1038/onc.2012.284. Epub 2012 Jul 9.

44.

Reconstitution of in vivo macrophage-tumor cell pairing and streaming motility on one-dimensional micro-patterned substrates.

Sharma VP, Beaty BT, Patsialou A, Liu H, Clarke M, Cox D, Condeelis JS, Eddy RJ.

Intravital. 2012 Jul 1;1(1):77-85.

45.

Development path and current status of the NANIVID: a new device for cancer cell studies.

Raja WK, Padgen MR, Williams JK, Gertler FB, Wyckoff JB, Condeelis JS, Castracane J.

J Micro Nanolithogr MEMS MOEMS. 2012 Mar 29;11(1). pii: 013013.

46.

Correlated immunohistochemical and cytological assays for the prediction of hematogenous dissemination of breast cancer.

Oktay MH, Gertler FB, Liu YF, Rohan TE, Condeelis JS, Jones JG.

J Histochem Cytochem. 2012 Mar;60(3):168-73. doi: 10.1369/0022155411435153. Epub 2012 Jan 3. Review.

47.

Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis.

Hernandez L, Magalhaes MA, Coniglio SJ, Condeelis JS, Segall JE.

Breast Cancer Res. 2011;13(6):R128. doi: 10.1186/bcr3074. Epub 2011 Dec 9.

48.

An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.

Shapiro IM, Cheng AW, Flytzanis NC, Balsamo M, Condeelis JS, Oktay MH, Burge CB, Gertler FB.

PLoS Genet. 2011 Aug;7(8):e1002218. doi: 10.1371/journal.pgen.1002218. Epub 2011 Aug 18.

49.

A photoswitchable orange-to-far-red fluorescent protein, PSmOrange.

Subach OM, Patterson GH, Ting LM, Wang Y, Condeelis JS, Verkhusha VV.

Nat Methods. 2011 Jul 31;8(9):771-7. doi: 10.1038/nmeth.1664.

50.

Chemotaxis in cancer.

Roussos ET, Condeelis JS, Patsialou A.

Nat Rev Cancer. 2011 Jul 22;11(8):573-87. doi: 10.1038/nrc3078. Review.

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