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Items: 1 to 50 of 296

1.

Black race and distant recurrence after neoadjuvant or adjuvant chemotherapy in breast cancer.

Pastoriza JM, Karagiannis GS, Lin J, Lanjewar S, Entenberg D, Condeelis JS, Sparano JA, Xue X, Rohan TE, Oktay MH.

Clin Exp Metastasis. 2018 Aug 22. doi: 10.1007/s10585-018-9932-8. [Epub ahead of print]

PMID:
30136072
2.

The Different Routes to Metastasis via Hypoxia-Regulated Programs.

Nobre AR, Entenberg D, Wang Y, Condeelis J, Aguirre-Ghiso JA.

Trends Cell Biol. 2018 Jul 21. pii: S0962-8924(18)30109-0. doi: 10.1016/j.tcb.2018.06.008. [Epub ahead of print] Review.

PMID:
30041830
3.

Myosin-IIA heavy chain phosphorylation on S1943 regulates tumor metastasis.

Norwood Toro LE, Wang Y, Condeelis JS, Jones JG, Backer JM, Bresnick AR.

Exp Cell Res. 2018 Sep 15;370(2):273-282. doi: 10.1016/j.yexcr.2018.06.028. Epub 2018 Jun 25.

PMID:
29953877
4.

Targeting invadopodia-mediated breast cancer metastasis by using ABL kinase inhibitors.

Meirson T, Genna A, Lukic N, Makhnii T, Alter J, Sharma VP, Wang Y, Samson AO, Condeelis JS, Gil-Henn H.

Oncotarget. 2018 Apr 24;9(31):22158-22183. doi: 10.18632/oncotarget.25243. eCollection 2018 Apr 24.

5.

A Unidirectional Transition from Migratory to Perivascular Macrophage Is Required for Tumor Cell Intravasation.

Arwert EN, Harney AS, Entenberg D, Wang Y, Sahai E, Pollard JW, Condeelis JS.

Cell Rep. 2018 May 1;23(5):1239-1248. doi: 10.1016/j.celrep.2018.04.007.

6.

A novel neuregulin - jagged1 paracrine loop in breast cancer transendothelial migration.

Cabrera RM, Mao SPH, Surve CR, Condeelis JS, Segall JE.

Breast Cancer Res. 2018 Apr 10;20(1):24. doi: 10.1186/s13058-018-0960-8.

7.

Chemotherapy-induced metastasis in breast cancer.

Karagiannis GS, Condeelis JS, Oktay MH.

Oncotarget. 2017 Nov 27;8(67):110733-110734. doi: 10.18632/oncotarget.22717. eCollection 2017 Dec 19. No abstract available.

8.

Chemotherapy-induced metastasis: mechanisms and translational opportunities.

Karagiannis GS, Condeelis JS, Oktay MH.

Clin Exp Metastasis. 2018 Apr;35(4):269-284. doi: 10.1007/s10585-017-9870-x. Epub 2018 Jan 6.

PMID:
29307118
9.

Macrophages orchestrate breast cancer early dissemination and metastasis.

Linde N, Casanova-Acebes M, Sosa MS, Mortha A, Rahman A, Farias E, Harper K, Tardio E, Reyes Torres I, Jones J, Condeelis J, Merad M, Aguirre-Ghiso JA.

Nat Commun. 2018 Jan 2;9(1):21. doi: 10.1038/s41467-017-02481-5.

10.

Corrigendum: Mechanism of early dissemination and metastasis in Her2+ mammary cancer.

Harper KL, Sosa MS, Entenberg D, Hosseini H, Cheung JF, Nobre R, Avivar-Valderas A, Nagi C, Girnius N, Davis RJ, Farias EF, Condeelis J, Klein CA, Aguirre-Ghiso JA.

Nature. 2018 Jan 18;553(7688):366. doi: 10.1038/nature24666. Epub 2017 Dec 13.

PMID:
29236689
11.

Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo.

Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Kargl J, Yang GH, di Martino J, Hernandez RE, Gast CE, Zarour LR, Antoku S, Houghton AM, Bravo-Cordero JJ, Wong MH, Condeelis J, Moens CB.

Dev Cell. 2017 Dec 4;43(5):549-562.e6. doi: 10.1016/j.devcel.2017.11.003.

PMID:
29207258
12.

A permanent window for the murine lung enables high-resolution imaging of cancer metastasis.

Entenberg D, Voiculescu S, Guo P, Borriello L, Wang Y, Karagiannis GS, Jones J, Baccay F, Oktay M, Condeelis J.

Nat Methods. 2018 Jan;15(1):73-80. doi: 10.1038/nmeth.4511. Epub 2017 Nov 27.

13.

A metastasis biomarker (MetaSite Breast™ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer.

Sparano JA, Gray R, Oktay MH, Entenberg D, Rohan T, Xue X, Donovan M, Peterson M, Shuber A, Hamilton DA, D'Alfonso T, Goldstein LJ, Gertler F, Davidson NE, Condeelis J, Jones J.

NPJ Breast Cancer. 2017 Nov 8;3:42. doi: 10.1038/s41523-017-0043-5. eCollection 2017.

14.

Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells.

Genna A, Lapetina S, Lukic N, Twafra S, Meirson T, Sharma VP, Condeelis JS, Gil-Henn H.

J Cell Biol. 2018 Jan 2;217(1):375-395. doi: 10.1083/jcb.201702184. Epub 2017 Nov 13.

15.

Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation.

Donnelly SK, Cabrera R, Mao SPH, Christin JR, Wu B, Guo W, Bravo-Cordero JJ, Condeelis JS, Segall JE, Hodgson L.

J Cell Biol. 2017 Dec 4;216(12):4331-4349. doi: 10.1083/jcb.201704048. Epub 2017 Oct 23.

16.

Time-lapsed, large-volume, high-resolution intravital imaging for tissue-wide analysis of single cell dynamics.

Entenberg D, Pastoriza JM, Oktay MH, Voiculescu S, Wang Y, Sosa MS, Aguirre-Ghiso J, Condeelis J.

Methods. 2017 Sep 1;128:65-77. doi: 10.1016/j.ymeth.2017.07.019.

17.

The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors.

Harney AS, Karagiannis GS, Pignatelli J, Smith BD, Kadioglu E, Wise SC, Hood MM, Kaufman MD, Leary CB, Lu WP, Al-Ani G, Chen X, Entenberg D, Oktay MH, Wang Y, Chun L, De Palma M, Jones JG, Flynn DL, Condeelis JS.

Mol Cancer Ther. 2017 Nov;16(11):2486-2501. doi: 10.1158/1535-7163.MCT-17-0241. Epub 2017 Aug 24.

PMID:
28838996
18.

A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cells.

Jiang C, Ding Z, Joy M, Chakraborty S, Kim SH, Bottcher R, Condeelis J, Singh S, Roy P.

Cell Cycle. 2017;16(24):2366-2373. doi: 10.1080/15384101.2017.1346759.

19.

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.

Karagiannis GS, Pastoriza JM, Wang Y, Harney AS, Entenberg D, Pignatelli J, Sharma VP, Xue EA, Cheng E, D'Alfonso TM, Jones JG, Anampa J, Rohan TE, Sparano JA, Condeelis JS, Oktay MH.

Sci Transl Med. 2017 Jul 5;9(397). pii: eaan0026. doi: 10.1126/scitranslmed.aan0026. Erratum in: Sci Transl Med. 2017 Jul 19;9(399):.

20.

Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis.

Eddy RJ, Weidmann MD, Sharma VP, Condeelis JS.

Trends Cell Biol. 2017 Aug;27(8):595-607. doi: 10.1016/j.tcb.2017.03.003. Epub 2017 Apr 12. Review.

21.

Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.

Rosenberg BJ, Gil-Henn H, Mader CC, Halo T, Yin T, Condeelis J, Machida K, Wu YI, Koleske AJ.

Mol Biol Cell. 2017 May 15;28(10):1347-1360. doi: 10.1091/mbc.E16-12-0885. Epub 2017 Mar 29.

22.

Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments.

Fluegen G, Avivar-Valderas A, Wang Y, Padgen MR, Williams JK, Nobre AR, Calvo V, Cheung JF, Bravo-Cordero JJ, Entenberg D, Castracane J, Verkhusha V, Keely PJ, Condeelis J, Aguirre-Ghiso JA.

Nat Cell Biol. 2017 Feb;19(2):120-132. doi: 10.1038/ncb3465. Epub 2017 Jan 23.

23.

Mechanism of early dissemination and metastasis in Her2+ mammary cancer.

Harper KL, Sosa MS, Entenberg D, Hosseini H, Cheung JF, Nobre R, Avivar-Valderas A, Nagi C, Girnius N, Davis RJ, Farias EF, Condeelis J, Klein CA, Aguirre-Ghiso JA.

Nature. 2016 Dec 14. doi: 10.1038/nature20609. [Epub ahead of print] Erratum in: Nature. 2017 Dec 13;:.

24.

Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation.

Pignatelli J, Bravo-Cordero JJ, Roh-Johnson M, Gandhi SJ, Wang Y, Chen X, Eddy RJ, Xue A, Singer RH, Hodgson L, Oktay MH, Condeelis JS.

Sci Rep. 2016 Nov 30;6:37874. doi: 10.1038/srep37874.

25.

Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway.

Leung E, Xue A, Wang Y, Rougerie P, Sharma VP, Eddy R, Cox D, Condeelis J.

Oncogene. 2017 May 11;36(19):2680-2692. doi: 10.1038/onc.2016.421. Epub 2016 Nov 28.

26.

MenaINV dysregulates cortactin phosphorylation to promote invadopodium maturation.

Weidmann MD, Surve CR, Eddy RJ, Chen X, Gertler FB, Sharma VP, Condeelis JS.

Sci Rep. 2016 Nov 8;6:36142. doi: 10.1038/srep36142.

27.

Direct visualization of the phenotype of hypoxic tumor cells at single cell resolution in vivo using a new hypoxia probe.

Wang Y, Wang H, Li J, Entenberg D, Xue A, Wang W, Condeelis J.

Intravital. 2016;5(2). pii: e1187803. Epub 2016 May 16.

28.

Validation of a device for the active manipulation of the tumor microenvironment during intravital imaging.

Williams JK, Entenberg D, Wang Y, Avivar-Valderas A, Padgen M, Clark A, Aguirre-Ghiso JA, Castracane J, Condeelis JS.

Intravital. 2016;5(2). pii: e1182271. Epub 2016 Apr 29.

29.

Long-term High-Resolution Intravital Microscopy in the Lung with a Vacuum Stabilized Imaging Window.

Rodriguez-Tirado C, Kitamura T, Kato Y, Pollard JW, Condeelis JS, Entenberg D.

J Vis Exp. 2016 Oct 6;(116). doi: 10.3791/54603.

30.

The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior.

Balsamo M, Mondal C, Carmona G, McClain LM, Riquelme DN, Tadros J, Ma D, Vasile E, Condeelis JS, Lauffenburger DA, Gertler FB.

Sci Rep. 2016 Oct 17;6:35298. doi: 10.1038/srep35298.

31.

Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells.

Morris BA, Burkel B, Ponik SM, Fan J, Condeelis JS, Aguirre-Ghiso JA, Castracane J, Denu JM, Keely PJ.

EBioMedicine. 2016 Nov;13:146-156. doi: 10.1016/j.ebiom.2016.10.012. Epub 2016 Oct 8.

32.

Extended Time-lapse Intravital Imaging of Real-time Multicellular Dynamics in the Tumor Microenvironment.

Harney AS, Wang Y, Condeelis JS, Entenberg D.

J Vis Exp. 2016 Jun 12;(112). doi: 10.3791/54042.

33.

In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging.

Szulczewski JM, Inman DR, Entenberg D, Ponik SM, Aguirre-Ghiso J, Castracane J, Condeelis J, Eliceiri KW, Keely PJ.

Sci Rep. 2016 May 25;6:25086. doi: 10.1038/srep25086.

34.

Signatures of breast cancer metastasis at a glance.

Karagiannis GS, Goswami S, Jones JG, Oktay MH, Condeelis JS.

J Cell Sci. 2016 May 1;129(9):1751-8. doi: 10.1242/jcs.183129. Epub 2016 Apr 15. Review.

35.

GPCR Signaling Mediates Tumor Metastasis via PI3Kβ.

Khalil BD, Hsueh C, Cao Y, Abi Saab WF, Wang Y, Condeelis JS, Bresnick AR, Backer JM.

Cancer Res. 2016 May 15;76(10):2944-53. doi: 10.1158/0008-5472.CAN-15-1675. Epub 2016 Mar 24.

36.

Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE.

Carmona G, Perera U, Gillett C, Naba A, Law AL, Sharma VP, Wang J, Wyckoff J, Balsamo M, Mosis F, De Piano M, Monypenny J, Woodman N, McConnell RE, Mouneimne G, Van Hemelrijck M, Cao Y, Condeelis J, Hynes RO, Gertler FB, Krause M.

Oncogene. 2016 Sep 29;35(39):5155-69. doi: 10.1038/onc.2016.47. Epub 2016 Mar 21.

37.

In vivo subcellular resolution optical imaging in the lung reveals early metastatic proliferation and motility.

Entenberg D, Rodriguez-Tirado C, Kato Y, Kitamura T, Pollard JW, Condeelis J.

Intravital. 2015 Sep-Dec;4(3). pii: e1086613.

38.

3-D individual cell based computational modeling of tumor cell-macrophage paracrine signaling mediated by EGF and CSF-1 gradients.

Knutsdottir H, Condeelis JS, Palsson E.

Integr Biol (Camb). 2016 Jan;8(1):104-19. doi: 10.1039/c5ib00201j. Epub 2015 Dec 21.

39.

Characterization of the expression of the pro-metastatic Mena(INV) isoform during breast tumor progression.

Oudin MJ, Hughes SK, Rohani N, Moufarrej MN, Jones JG, Condeelis JS, Lauffenburger DA, Gertler FB.

Clin Exp Metastasis. 2016 Mar;33(3):249-61. doi: 10.1007/s10585-015-9775-5. Epub 2015 Dec 17.

40.

Brightness-equalized quantum dots.

Lim SJ, Zahid MU, Le P, Ma L, Entenberg D, Harney AS, Condeelis J, Smith AM.

Nat Commun. 2015 Oct 5;6:8210. doi: 10.1038/ncomms9210.

41.

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.

Hughes SK, Oudin MJ, Tadros J, Neil J, Del Rosario A, Joughin BA, Ritsma L, Wyckoff J, Vasile E, Eddy R, Philippar U, Lussiez A, Condeelis JS, van Rheenen J, White F, Lauffenburger DA, Gertler FB.

Mol Biol Cell. 2015 Nov 1;26(21):3867-78. doi: 10.1091/mbc.E15-06-0442. Epub 2015 Sep 2.

42.

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA.

Harney AS, Arwert EN, Entenberg D, Wang Y, Guo P, Qian BZ, Oktay MH, Pollard JW, Jones JG, Condeelis JS.

Cancer Discov. 2015 Sep;5(9):932-43. doi: 10.1158/2159-8290.CD-15-0012. Epub 2015 Aug 12.

43.

MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial Activity in Head and Neck Squamous Cell Carcinoma.

Jimenez L, Sharma VP, Condeelis J, Harris T, Ow TJ, Prystowsky MB, Childs G, Segall JE.

Arch Pathol Lab Med. 2015 Nov;139(11):1349-61. doi: 10.5858/arpa.2014-0471-OA. Epub 2015 Jul 14.

44.

Menacalc, a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer.

Forse CL, Agarwal S, Pinnaduwage D, Gertler F, Condeelis JS, Lin J, Xue X, Johung K, Mulligan AM, Rohan TE, Bull SB, Andrulis IL.

BMC Cancer. 2015 Jun 27;15:483. doi: 10.1186/s12885-015-1468-6.

45.

Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance.

Zolla V, Nizamutdinova IT, Scharf B, Clement CC, Maejima D, Akl T, Nagai T, Luciani P, Leroux JC, Halin C, Stukes S, Tiwari S, Casadevall A, Jacobs WR Jr, Entenberg D, Zawieja DC, Condeelis J, Fooksman DR, Gashev AA, Santambrogio L.

Aging Cell. 2015 Aug;14(4):582-94. doi: 10.1111/acel.12330. Epub 2015 May 15.

46.

A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.

Moshfegh Y, Bravo-Cordero JJ, Miskolci V, Condeelis J, Hodgson L.

Nat Cell Biol. 2015 Mar;17(3):350. doi: 10.1038/ncb3123. No abstract available.

PMID:
25720965
47.

Profilin1 regulates invadopodium maturation in human breast cancer cells.

Valenzuela-Iglesias A, Sharma VP, Beaty BT, Ding Z, Gutierrez-Millan LE, Roy P, Condeelis JS, Bravo-Cordero JJ.

Eur J Cell Biol. 2015 Feb;94(2):78-89. doi: 10.1016/j.ejcb.2014.12.002. Epub 2014 Dec 31.

48.

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration.

Pignatelli J, Goswami S, Jones JG, Rohan TE, Pieri E, Chen X, Adler E, Cox D, Maleki S, Bresnick A, Gertler FB, Condeelis JS, Oktay MH.

Sci Signal. 2014 Nov 25;7(353):ra112. doi: 10.1126/scisignal.2005329.

49.

Imaging tumour heterogeneity of the consequences of a PKCα-substrate interaction in breast cancer patients.

Weitsman G, Lawler K, Kelleher MT, Barrett JE, Barber PR, Shamil E, Festy F, Patel G, Fruhwirth GO, Huang L, Tullis ID, Woodman N, Ofo E, Ameer-Beg SM, Irshad S, Condeelis J, Gillett CE, Ellis PA, Vojnovic B, Coolen AC, Ng T.

Biochem Soc Trans. 2014 Dec;42(6):1498-505. doi: 10.1042/BST20140165. Review.

50.

Multiparametric classification links tumor microenvironments with tumor cell phenotype.

Gligorijevic B, Bergman A, Condeelis J.

PLoS Biol. 2014 Nov 11;12(11):e1001995. doi: 10.1371/journal.pbio.1001995. eCollection 2014 Nov.

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