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Items: 24


Level of FACT defines the transcriptional landscape and aggressive phenotype of breast cancer cells.

Fleyshman D, Prendergast L, Safina A, Paszkiewicz G, Commane M, Morgan K, Attwood K, Gurova K.

Oncotarget. 2017 Mar 28;8(13):20525-20542. doi: 10.18632/oncotarget.15656.


An Irish outbreak of New Delhi metallo-β-lactamase (NDM)-1 carbapenemase-producing Enterobacteriaceae: increasing but unrecognized prevalence.

O'Connor C, Cormican M, Boo TW, McGrath E, Slevin B, O'Gorman A, Commane M, Mahony S, O'Donovan E, Powell J, Monahan R, Finnegan C, Kiernan MG, Coffey JC, Power L, O'Connell NH, Dunne CP.

J Hosp Infect. 2016 Dec;94(4):351-357. doi: 10.1016/j.jhin.2016.08.005. Epub 2016 Aug 19.


Limerick: forever associated with five lines of rhyme or infamous for irrepressible carbapenemase-producing Enterobacteriaceae for all time?

O'Connor C, O'Connell NH, Commane M, O'Donovan E, Power L, Dunne CP.

J Hosp Infect. 2016 Jun;93(2):155-6. doi: 10.1016/j.jhin.2016.03.008. Epub 2016 Mar 31. No abstract available.


ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin.

Fleyshman D, Cheney P, Ströse A, Mudambi S, Safina A, Commane M, Purmal A, Morgan K, Wang NJ, Gray J, Spellman PT, Issaeva N, Gurova K.

Cell Cycle. 2016;15(3):455-70. doi: 10.1080/15384101.2015.1127478. Epub 2015 Dec 22.


Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer.

Burkhart C, Fleyshman D, Kohrn R, Commane M, Garrigan J, Kurbatov V, Toshkov I, Ramachandran R, Martello L, Gurova KV.

Oncotarget. 2014 Nov 30;5(22):11038-53.


Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells.

Safina A, Garcia H, Commane M, Guryanova O, Degan S, Kolesnikova K, Gurova KV.

Cell Cycle. 2013 Aug 1;12(15):2423-34. doi: 10.4161/cc.25452. Epub 2013 Jun 28.


Facilitates chromatin transcription complex is an "accelerator" of tumor transformation and potential marker and target of aggressive cancers.

Garcia H, Miecznikowski JC, Safina A, Commane M, Ruusulehto A, Kilpinen S, Leach RW, Attwood K, Li Y, Degan S, Omilian AR, Guryanova O, Papantonopoulou O, Wang J, Buck M, Liu S, Morrison C, Gurova KV.

Cell Rep. 2013 Jul 11;4(1):159-73. doi: 10.1016/j.celrep.2013.06.013. Epub 2013 Jul 3.


Targeting FACT complex suppresses mammary tumorigenesis in Her2/neu transgenic mice.

Koman IE, Commane M, Paszkiewicz G, Hoonjan B, Pal S, Safina A, Toshkov I, Purmal AA, Wang D, Liu S, Morrison C, Gudkov AV, Gurova KV.

Cancer Prev Res (Phila). 2012 Aug;5(8):1025-35. doi: 10.1158/1940-6207.CAPR-11-0529. Epub 2012 Jun 11.


Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells.

Garcia H, Fleyshman D, Kolesnikova K, Safina A, Commane M, Paszkiewicz G, Omelian A, Morrison C, Gurova K.

Oncotarget. 2011 Oct;2(10):783-96.


Curaxins: anticancer compounds that simultaneously suppress NF-κB and activate p53 by targeting FACT.

Gasparian AV, Burkhart CA, Purmal AA, Brodsky L, Pal M, Saranadasa M, Bosykh DA, Commane M, Guryanova OA, Pal S, Safina A, Sviridov S, Koman IE, Veith J, Komar AA, Gudkov AV, Gurova KV.

Sci Transl Med. 2011 Aug 10;3(95):95ra74. doi: 10.1126/scitranslmed.3002530.


Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction.

O'Connell K, Boo TW, Keady D, Niriain U, O'Donovan D, Commane M, Faherty C, Cormican M.

J Hosp Infect. 2011 Apr;77(4):338-42. doi: 10.1016/j.jhin.2010.12.012. Epub 2011 Feb 16.


A pseudo-outbreak of Fusarium solani in an intensive care unit associated with bronchoscopy.

Schaffer K, Fitzgerald SF, Commane M, Maguiness A, Fenelon LE.

J Hosp Infect. 2008 Aug;69(4):400-2. doi: 10.1016/j.jhin.2008.03.008. Epub 2008 Jun 3. No abstract available.


Mutant human cells with constitutive activation of NF-kappaB.

Sathe SS, Sizemore N, Li X, Vithalani K, Commane M, Swiatkowski SM, Stark GR.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):192-7. Epub 2003 Dec 22.


IRAK-dependent phosphorylation of Stat1 on serine 727 in response to interleukin-1 and effects on gene expression.

Nguyen H, Chatterjee-Kishore M, Jiang Z, Qing Y, Ramana CV, Bayes J, Commane M, Li X, Stark GR.

J Interferon Cytokine Res. 2003 Apr;23(4):183-92.


IRAK and TAK1 are required for IL-18-mediated signaling.

Wald D, Commane M, Stark GR, Li X.

Eur J Immunol. 2001 Dec;31(12):3747-54.


IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B.

Qian Y, Commane M, Ninomiya-Tsuji J, Matsumoto K, Li X.

J Biol Chem. 2001 Nov 9;276(45):41661-7. Epub 2001 Aug 22.


IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK).

Li X, Commane M, Jiang Z, Stark GR.

Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4461-5. Epub 2001 Apr 3.


Act1, an NF-kappa B-activating protein.

Li X, Commane M, Nie H, Hua X, Chatterjee-Kishore M, Wald D, Haag M, Stark GR.

Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10489-93.


Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase.

Li X, Commane M, Burns C, Vithalani K, Cao Z, Stark GR.

Mol Cell Biol. 1999 Jul;19(7):4643-52.


Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases.

Kumar A, Commane M, Flickinger TW, Horvath CM, Stark GR.

Science. 1997 Nov 28;278(5343):1630-2.


Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor.

Leaman DW, Pisharody S, Flickinger TW, Commane MA, Schlessinger J, Kerr IM, Levy DE, Stark GR.

Mol Cell Biol. 1996 Jan;16(1):369-75.


Induction of gene amplification by 5-aza-2'-deoxycytidine.

Perry ME, Rolfe M, McIntyre P, Commane M, Stark GR.

Mutat Res. 1992 May;276(3):189-97.


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