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Items: 32

1.

A genetic model to study O-GlcNAc cycling in immortalized mouse embryonic fibroblasts.

St Amand MM, Bond MR, Riedy J, Comly M, Shiloach J, Hanover JA.

J Biol Chem. 2018 Aug 31;293(35):13673-13681. doi: 10.1074/jbc.RA118.004059. Epub 2018 Jun 28.

2.

Nutrient-driven O-linked N-acetylglucosamine (O-GlcNAc) cycling impacts neurodevelopmental timing and metabolism.

Olivier-Van Stichelen S, Wang P, Comly M, Love DC, Hanover JA.

J Biol Chem. 2017 Apr 14;292(15):6076-6085. doi: 10.1074/jbc.M116.774042. Epub 2017 Feb 28.

3.

Conditional knock-out reveals a requirement for O-linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis.

Keembiyehetty C, Love DC, Harwood KR, Gavrilova O, Comly ME, Hanover JA.

J Biol Chem. 2015 Mar 13;290(11):7097-113. doi: 10.1074/jbc.M114.617779. Epub 2015 Jan 16.

4.

Differential trafficking of the Niemann-Pick C1 and 2 proteins highlights distinct roles in late endocytic lipid trafficking.

Zhang M, Sun M, Dwyer NK, Comly ME, Patel SC, Sundaram R, Hanover JA, Blanchette-Mackie EJ.

Acta Paediatr Suppl. 2003 Dec;92(443):63-73; discussion 45.

PMID:
14989468
5.

The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease.

Neufeld EB, Stonik JA, Demosky SJ Jr, Knapper CL, Combs CA, Cooney A, Comly M, Dwyer N, Blanchette-Mackie J, Remaley AT, Santamarina-Fojo S, Brewer HB Jr.

J Biol Chem. 2004 Apr 9;279(15):15571-8. Epub 2004 Jan 27.

6.

MLN64 mediates mobilization of lysosomal cholesterol to steroidogenic mitochondria.

Zhang M, Liu P, Dwyer NK, Christenson LK, Fujimoto T, Martinez F, Comly M, Hanover JA, Blanchette-Mackie EJ, Strauss JF 3rd.

J Biol Chem. 2002 Sep 6;277(36):33300-10. Epub 2002 Jun 17.

7.

Cellular localization and trafficking of the human ABCA1 transporter.

Neufeld EB, Remaley AT, Demosky SJ, Stonik JA, Cooney AM, Comly M, Dwyer NK, Zhang M, Blanchette-Mackie J, Santamarina-Fojo S, Brewer HB Jr.

J Biol Chem. 2001 Jul 20;276(29):27584-90. Epub 2001 May 10.

8.

Cessation of rapid late endosomal tubulovesicular trafficking in Niemann-Pick type C1 disease.

Zhang M, Dwyer NK, Love DC, Cooney A, Comly M, Neufeld E, Pentchev PG, Blanchette-Mackie EJ, Hanover JA.

Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4466-71.

9.

Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes.

Zhang M, Dwyer NK, Neufeld EB, Love DC, Cooney A, Comly M, Patel S, Watari H, Strauss JF 3rd, Pentchev PG, Hanover JA, Blanchette-Mackie EJ.

J Biol Chem. 2001 Feb 2;276(5):3417-25. Epub 2000 Oct 13.

10.

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis.

Carstea ED, Morris JA, Coleman KG, Loftus SK, Zhang D, Cummings C, Gu J, Rosenfeld MA, Pavan WJ, Krizman DB, Nagle J, Polymeropoulos MH, Sturley SL, Ioannou YA, Higgins ME, Comly M, Cooney A, Brown A, Kaneski CR, Blanchette-Mackie EJ, Dwyer NK, Neufeld EB, Chang TY, Liscum L, Strauss JF 3rd, Ohno K, Zeigler M, Carmi R, Sokol J, Markie D, O'Neill RR, van Diggelen OP, Elleder M, Patterson MC, Brady RO, Vanier MT, Pentchev PG, Tagle DA.

Science. 1997 Jul 11;277(5323):228-31.

11.

Substantial narrowing of the Niemann-Pick C candidate interval by yeast artificial chromosome complementation.

Gu JZ, Carstea ED, Cummings C, Morris JA, Loftus SK, Zhang D, Coleman KG, Cooney AM, Comly ME, Fandino L, Roff C, Tagle DA, Pavan WJ, Pentchev PG, Rosenfeld MA.

Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7378-83.

12.

Cholesterol deprivation affects the fluorescence properties of a ceramide analog at the Golgi apparatus of living cells.

Martin OC, Comly ME, Blanchette-Mackie EJ, Pentchev PG, Pagano RE.

Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2661-5.

13.

Progesterone blocks cholesterol translocation from lysosomes.

Butler JD, Blanchette-Mackie J, Goldin E, O'Neill RR, Carstea G, Roff CF, Patterson MC, Patel S, Comly ME, Cooney A, et al.

J Biol Chem. 1992 Nov 25;267(33):23797-805.

14.

Clinical, pathologic, and biochemical features of a cholesterol lipidosis accompanied by hyperlipidemia and xanthomas.

Filling-Katz MR, Miller SP, Merrick HF, Travis WD, Gregg RE, Tsokos M, Comly M, Kaneski CR, Mackie S, Lebovics RS, et al.

Neurology. 1992 Sep;42(9):1768-74.

PMID:
1513468
15.

Niemann-Pick type-C disease: deficient intracellular transport of exogenously derived cholesterol.

Roff CF, Goldin E, Comly ME, Blanchette-Mackie J, Cooney A, Brady RO, Pentchev PG.

Am J Med Genet. 1992 Feb 15;42(4):593-8.

PMID:
1609841
16.

Type C Niemann-Pick disease: cellular uncoupling of cholesterol homeostasis is linked to the severity of disruption in the intracellular transport of exogenously derived cholesterol.

Argoff CE, Comly ME, Blanchette-Mackie J, Kruth HS, Pye HT, Goldin E, Kaneski C, Vanier MT, Brady RO, Pentchev PG.

Biochim Biophys Acta. 1991 Jun 5;1096(4):319-27.

PMID:
2065103
17.

Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport.

Roff CF, Goldin E, Comly ME, Cooney A, Brown A, Vanier MT, Miller SP, Brady RO, Pentchev PG.

Dev Neurosci. 1991;13(4-5):315-9. Review.

PMID:
1817037
18.

Type C Niemann-Pick disease: documentation of abnormal LDL processing in lymphocytes.

Argoff CE, Kaneski CR, Blanchette-Mackie EJ, Comly M, Dwyer NK, Brown A, Brady RO, Pentchev PG.

Biochem Biophys Res Commun. 1990 Aug 31;171(1):38-45.

PMID:
2393397
19.

Type C Niemann-Pick disease: dimethyl sulfoxide moderates abnormal LDL-cholesterol processing in mutant fibroblasts.

Blanchette Mackie EJ, Dwyer NK, Vanier MT, Sokol J, Merrick HF, Comly ME, Argoff CE, Pentchev PG.

Biochim Biophys Acta. 1989 Nov 28;1006(2):219-26.

PMID:
2688743
20.

Clinical spectrum of Niemann-Pick disease type C.

Fink JK, Filling-Katz MR, Sokol J, Cogan DG, Pikus A, Sonies B, Soong B, Pentchev PG, Comly ME, Brady RO, et al.

Neurology. 1989 Aug;39(8):1040-9.

PMID:
2761697
21.

Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes.

Blanchette-Mackie EJ, Dwyer NK, Amende LM, Kruth HS, Butler JD, Sokol J, Comly ME, Vanier MT, August JT, Brady RO, et al.

Proc Natl Acad Sci U S A. 1988 Nov;85(21):8022-6.

22.

Cholesteryl ester storage disease: a patient with massive splenomegaly and splenic abscess.

Edelstein RA, Filling-Katz MR, Pentchev P, Gal A, Chandra R, Shawker T, Guzzetta P, Comly M, Kaneski C, Brady RO, et al.

Am J Gastroenterol. 1988 Jun;83(6):687-92.

PMID:
3376925
23.

Niemann-Pick disease group C: clinical variability and diagnosis based on defective cholesterol esterification. A collaborative study on 70 patients.

Vanier MT, Wenger DA, Comly ME, Rousson R, Brady RO, Pentchev PG.

Clin Genet. 1988 May;33(5):331-48.

PMID:
3378364
24.

Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol.

Sokol J, Blanchette-Mackie J, Kruth HS, Dwyer NK, Amende LM, Butler JD, Robinson E, Patel S, Brady RO, Comly ME, et al.

J Biol Chem. 1988 Mar 5;263(7):3411-7.

25.

Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts.

Pentchev PG, Comly ME, Kruth HS, Tokoro T, Butler J, Sokol J, Filling-Katz M, Quirk JM, Marshall DC, Patel S, et al.

FASEB J. 1987 Jul;1(1):40-5.

PMID:
3609608
26.

Niemann-pick variant disorders: comparison of errors of cellular cholesterol homeostasis in group D and group C fibroblasts.

Butler JD, Comly ME, Kruth HS, Vanier M, Filling-Katz M, Fink J, Barton N, Weintroub H, Quirk JM, Tokoro T, et al.

Proc Natl Acad Sci U S A. 1987 Jan;84(2):556-60.

27.
28.

Type C Niemann-Pick disease. Abnormal metabolism of low density lipoprotein in homozygous and heterozygous fibroblasts.

Kruth HS, Comly ME, Butler JD, Vanier MT, Fink JK, Wenger DA, Patel S, Pentchev PG.

J Biol Chem. 1986 Dec 15;261(35):16769-74.

30.

A defect in cholesterol esterification in Niemann-Pick disease (type C) patients.

Pentchev PG, Comly ME, Kruth HS, Vanier MT, Wenger DA, Patel S, Brady RO.

Proc Natl Acad Sci U S A. 1985 Dec;82(23):8247-51.

31.

Intrauterine growth retardation induced by thiamine deficiency and pyrithiamine during pregnancy in the rat.

Roecklein B, Levin SW, Comly M, Mukherjee AB.

Am J Obstet Gynecol. 1985 Feb 15;151(4):455-60.

PMID:
3976746
32.

Two pools of beta-endorphin-like immunoreactivity in blood: plasma and erythrocytes.

Fisher A, Comly M, Do R, Tamarkin L, Ghazanfari AF, Mukherjee AB.

Life Sci. 1984 May 7;34(19):1839-46.

PMID:
6330480

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