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Items: 39

1.

Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection.

Lane TR, Massey C, Comer JE, Anantpadma M, Freundlich JS, Davey RA, Madrid PB, Ekins S.

PLoS Negl Trop Dis. 2019 Nov 21;13(11):e0007890. doi: 10.1371/journal.pntd.0007890. eCollection 2019 Nov.

2.

Repurposing Quinacrine against Ebola Virus Infection In Vivo.

Lane TR, Comer JE, Freiberg AN, Madrid PB, Ekins S.

Antimicrob Agents Chemother. 2019 Aug 23;63(9). pii: e01142-19. doi: 10.1128/AAC.01142-19. Print 2019 Sep.

PMID:
31307979
3.

Immunogenicity and Efficacy of a Measles Virus-Vectored Chikungunya Vaccine in Nonhuman Primates.

Rossi SL, Comer JE, Wang E, Azar SR, Lawrence WS, Plante JA, Ramsauer K, Schrauf S, Weaver SC.

J Infect Dis. 2019 Jul 31;220(5):735-742. doi: 10.1093/infdis/jiz202.

4.

Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir.

Comer JE, Escaffre O, Neef N, Brasel T, Juelich TL, Smith JK, Smith J, Kalveram B, Perez DD, Massey S, Zhang L, Freiberg AN.

Viruses. 2019 Feb 3;11(2). pii: E137. doi: 10.3390/v11020137.

5.

Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection.

Ekins S, Lingerfelt MA, Comer JE, Freiberg AN, Mirsalis JC, O'Loughlin K, Harutyunyan A, McFarlane C, Green CE, Madrid PB.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e01711-17. doi: 10.1128/AAC.01711-17. Print 2018 Feb.

6.

Modeling Rabbit Responses to Single and Multiple Aerosol Exposures of Bacillus anthracis Spores.

Coleman ME, Marks HM, Bartrand TA, Donahue DW, Hines SA, Comer JE, Taft SC.

Risk Anal. 2017 May;37(5):943-957. doi: 10.1111/risa.12688. Epub 2017 Jan 25.

7.

First vaccine approval under the FDA Animal Rule.

Beasley DWC, Brasel TL, Comer JE.

NPJ Vaccines. 2016 Aug 25;1:16013. doi: 10.1038/npjvaccines.2016.13. eCollection 2016.

8.

Evaluation of intravenous anthrax immune globulin for treatment of inhalation anthrax.

Mytle N, Hopkins RJ, Malkevich NV, Basu S, Meister GT, Sanford DC, Comer JE, Van Zandt KE, Al-Ibrahim M, Kramer WG, Howard C, Daczkowski N, Chakrabarti AC, Ionin B, Nabors GS, Skiadopoulos MH.

Antimicrob Agents Chemother. 2013 Nov;57(11):5684-92. doi: 10.1128/AAC.00458-13. Epub 2013 Aug 26.

9.

Development of an inhalational Bacillus anthracis exposure therapeutic model in cynomolgus macaques.

Henning LN, Comer JE, Stark GV, Ray BD, Tordoff KP, Knostman KA, Meister GT.

Clin Vaccine Immunol. 2012 Nov;19(11):1765-75. doi: 10.1128/CVI.00288-12. Epub 2012 Sep 5.

10.

Achieving consistent multiple daily low-dose Bacillus anthracis spore inhalation exposures in the rabbit model.

Barnewall RE, Comer JE, Miller BD, Gutting BW, Wolfe DN, Director-Myska AE, Nichols TL, Taft SC.

Front Cell Infect Microbiol. 2012 Jun 13;2:71. doi: 10.3389/fcimb.2012.00071. eCollection 2012.

11.

Characterization of a therapeutic model of inhalational anthrax using an increase in body temperature in New Zealand white rabbits as a trigger for treatment.

Comer JE, Ray BD, Henning LN, Stark GV, Barnewall RE, Mott JM, Meister GT.

Clin Vaccine Immunol. 2012 Sep;19(9):1517-25. doi: 10.1128/CVI.00292-12. Epub 2012 Jul 25.

12.

Transcriptomic and innate immune responses to Yersinia pestis in the lymph node during bubonic plague.

Comer JE, Sturdevant DE, Carmody AB, Virtaneva K, Gardner D, Long D, Rosenke R, Porcella SF, Hinnebusch BJ.

Infect Immun. 2010 Dec;78(12):5086-98. doi: 10.1128/IAI.00256-10. Epub 2010 Sep 27.

13.

ADMET--Fifth Annual SMi Conference.

Comer JE.

IDrugs. 2010 Sep;13(9):610-4.

PMID:
20799141
14.

Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship.

Völgyi G, Baka E, Box KJ, Comer JE, Takács-Novák K.

Anal Chim Acta. 2010 Jul 12;673(1):40-6. doi: 10.1016/j.aca.2010.05.022. Epub 2010 Jun 16.

PMID:
20630176
15.

New ideas about the solubility of drugs.

Box K, Comer JE, Gravestock T, Stuart M.

Chem Biodivers. 2009 Nov;6(11):1767-88. doi: 10.1002/cbdv.200900164.

PMID:
19937815
16.

Using measured pKa, LogP and solubility to investigate supersaturation and predict BCS class.

Box KJ, Comer JE.

Curr Drug Metab. 2008 Nov;9(9):869-78. Review.

PMID:
18991583
17.

Examining the vector-host-pathogen interface with quantitative molecular tools.

Comer JE, Lorange EA, Hinnebusch BJ.

Methods Mol Biol. 2008;431:123-31.

PMID:
18287752
18.

Study of equilibrium solubility measurement by saturation shake-flask method using hydrochlorothiazide as model compound.

Baka E, Comer JE, Takács-Novák K.

J Pharm Biomed Anal. 2008 Jan 22;46(2):335-41. Epub 2007 Nov 1.

PMID:
18055153
19.

Human monoclonal antibody AVP-21D9 to protective antigen reduces dissemination of the Bacillus anthracis Ames strain from the lungs in a rabbit model.

Peterson JW, Comer JE, Baze WB, Noffsinger DM, Wenglikowski A, Walberg KG, Hardcastle J, Pawlik J, Bush K, Taormina J, Moen S, Thomas J, Chatuev BM, Sower L, Chopra AK, Stanberry LR, Sawada R, Scholz WW, Sircar J.

Infect Immun. 2007 Jul;75(7):3414-24. Epub 2007 Apr 23.

20.

Proteomic analyses of murine macrophages treated with Bacillus anthracis lethal toxin.

Sapra R, Gaucher SP, Lachmann JS, Buffleben GM, Chirica GS, Comer JE, Peterson JW, Chopra AK, Singh AK.

Microb Pathog. 2006 Oct-Nov;41(4-5):157-67. Epub 2006 Sep 1.

PMID:
16950595
21.

Murine macrophage transcriptional and functional responses to Bacillus anthracis edema toxin.

Comer JE, Galindo CL, Zhang F, Wenglikowski AM, Bush KL, Garner HR, Peterson JW, Chopra AK.

Microb Pathog. 2006 Aug-Sep;41(2-3):96-110. Epub 2006 Jul 18.

PMID:
16846716
22.

Evaluation of the protective effects of quinacrine against Bacillus anthracis Ames.

Comer JE, Noffsinger DM, McHenry DJ, Weisbaum DM, Chatuev BM, Chopra AK, Peterson JW.

J Toxicol Environ Health A. 2006 Jun;69(11):1083-95.

PMID:
16840255
23.

Equilibrium versus kinetic measurements of aqueous solubility, and the ability of compounds to supersaturate in solution--a validation study.

Box KJ, Völgyi G, Baka E, Stuart M, Takács-Novák K, Comer JE.

J Pharm Sci. 2006 Jun;95(6):1298-307.

PMID:
16552741
24.

Human monoclonal anti-protective antigen antibody completely protects rabbits and is synergistic with ciprofloxacin in protecting mice and guinea pigs against inhalation anthrax.

Peterson JW, Comer JE, Noffsinger DM, Wenglikowski A, Walberg KG, Chatuev BM, Chopra AK, Stanberry LR, Kang AS, Scholz WW, Sircar J.

Infect Immun. 2006 Feb;74(2):1016-24.

25.

Direct inhibition of T-lymphocyte activation by anthrax toxins in vivo.

Comer JE, Chopra AK, Peterson JW, König R.

Infect Immun. 2005 Dec;73(12):8275-81.

26.

Glycosylation substrate specificity of Pseudomonas aeruginosa 1244 pilin.

Horzempa J, Comer JE, Davis SA, Castric P.

J Biol Chem. 2006 Jan 13;281(2):1128-36. Epub 2005 Nov 11.

27.
28.

Plasmodium ookinete-secreted proteins secreted through a common micronemal pathway are targets of blocking malaria transmission.

Li F, Templeton TJ, Popov V, Comer JE, Tsuboi T, Torii M, Vinetz JM.

J Biol Chem. 2004 Jun 18;279(25):26635-44. Epub 2004 Apr 6.

29.

Novel Immunoreactive glycoprotein orthologs of Ehrlichia spp.

McBride JW, Comer JE, Walker DH.

Ann N Y Acad Sci. 2003 Jun;990:678-84.

PMID:
12860706
30.

Identification of the Pseudomonas aeruginosa 1244 pilin glycosylation site.

Comer JE, Marshall MA, Blanch VJ, Deal CD, Castric P.

Infect Immun. 2002 Jun;70(6):2837-45.

31.

PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent-water mixtures.

Avdeef A, Box KJ, Comer JE, Gilges M, Hadley M, Hibbert C, Patterson W, Tam KY.

J Pharm Biomed Anal. 1999 Aug;20(4):631-41.

PMID:
10704132
32.

Multiwavelength spectrophotometric determination of acid dissociation constants of ionizable drugs.

Allen RI, Box KJ, Comer JE, Peake C, Tam KY.

J Pharm Biomed Anal. 1998 Aug;17(4-5):699-712.

PMID:
9682153
33.

pH-metric logP 10. Determination of liposomal membrane-water partition coefficients of ionizable drugs.

Avdeef A, Box KJ, Comer JE, Hibbert C, Tam KY.

Pharm Res. 1998 Feb;15(2):209-15.

PMID:
9523305
34.

pH electrode performance under automated management conditions.

Comer JE, Hibbert C.

J Automat Chem. 1997;19(6):213-24.

35.

Validation of an ion selective electrode system for the analysis of serum fluoride ion.

Duly EB, Luney SR, Trinick TR, Murray JM, Comer JE.

J Automat Chem. 1995;17(6):219-23.

36.
37.

Novel ion-selective electrode system for the simultaneous determination of fluoride and calcium in acid solution.

Tyler JE, Comer JE.

Analyst. 1985 Jan;110(1):15-8. No abstract available.

PMID:
3985342
38.

Multiple hamartoma syndrome (Cowden's disease).

Weary PE, Gorlin RJ, Gentry WC Jr, Comer JE, Greer KE.

Arch Dermatol. 1972 Nov;106(5):682-90. No abstract available.

PMID:
4635800
39.

Treatment of tinea pedis with griseofulvin.

PRAZAK G, FERGUSON JS, COMER JE, McNEIL BS.

Arch Dermatol. 1960 May;81:821-6. No abstract available.

PMID:
14434705

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