Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 110

1.

Combining magnetic nanoparticles and icosahedral boron clusters in biocompatible inorganic nanohybrids for cancer therapy.

Oleshkevich E, Morancho A, Saha A, Galenkamp KMO, Grayston A, Crich SG, Alberti D, Protti N, Comella JX, Teixidor F, Rosell A, Viñas C.

Nanomedicine. 2019 May 3;20:101986. doi: 10.1016/j.nano.2019.03.008. [Epub ahead of print]

PMID:
31059794
2.

Syntaxin-1/TI-VAMP SNAREs interact with Trk receptors and are required for neurotrophin-dependent outgrowth.

Fuschini G, Cotrufo T, Ros O, Muhaisen A, Andrés R, Comella JX, Soriano E.

Oncotarget. 2018 Nov 13;9(89):35922-35940. doi: 10.18632/oncotarget.26307. eCollection 2018 Nov 13.

3.

Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease.

Gomez-Arboledas A, Davila JC, Sanchez-Mejias E, Navarro V, Nuñez-Diaz C, Sanchez-Varo R, Sanchez-Mico MV, Trujillo-Estrada L, Fernandez-Valenzuela JJ, Vizuete M, Comella JX, Galea E, Vitorica J, Gutierrez A.

Glia. 2018 Mar;66(3):637-653. doi: 10.1002/glia.23270. Epub 2017 Nov 27.

4.

Identification and characterization of new isoforms of human fas apoptotic inhibitory molecule (FAIM).

Coccia E, Calleja-Yagüe I, Planells-Ferrer L, Sanuy B, Sanz B, López-Soriano J, Moubarak RS, Munell F, Barneda-Zahonero B, Comella JX, Pérez-García MJ.

PLoS One. 2017 Oct 5;12(10):e0185327. doi: 10.1371/journal.pone.0185327. eCollection 2017.

5.

FAIM-L regulation of XIAP degradation modulates Synaptic Long-Term Depression and Axon Degeneration.

Martínez-Mármol R, Barneda-Zahonero B, Soto D, Andrés RM, Coccia E, Gasull X, Planells-Ferrer L, Moubarak RS, Soriano E, Comella JX.

Sci Rep. 2016 Oct 21;6:35775. doi: 10.1038/srep35775.

6.

Corrigendum: FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons.

Bosch C, Martínez A, Masachs N, Teixeira CM, Fernaud I, Ulloa F, Pérez-Martínez E, Lois C, Comella JX, DeFelipe J, Merchán-Pérez A, Soriano E.

Front Neuroanat. 2016 Oct 18;10:100. eCollection 2016.

7.

Reelin Regulates the Maturation of Dendritic Spines, Synaptogenesis and Glial Ensheathment of Newborn Granule Cells.

Bosch C, Masachs N, Exposito-Alonso D, Martínez A, Teixeira CM, Fernaud I, Pujadas L, Ulloa F, Comella JX, DeFelipe J, Merchán-Pérez A, Soriano E.

Cereb Cortex. 2016 Oct 17;26(11):4282-4298. doi: 10.1093/cercor/bhw216.

8.

Fas apoptosis inhibitory molecules: more than death-receptor antagonists in the nervous system.

Planells-Ferrer L, Urresti J, Coccia E, Galenkamp KM, Calleja-Yagüe I, López-Soriano J, Carriba P, Barneda-Zahonero B, Segura MF, Comella JX.

J Neurochem. 2016 Oct;139(1):11-21. doi: 10.1111/jnc.13729. Epub 2016 Aug 3. Review.

9.

BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways.

Jubierre L, Soriano A, Planells-Ferrer L, París-Coderch L, Tenbaum SP, Romero OA, Moubarak RS, Almazán-Moga A, Molist C, Roma J, Navarro S, Noguera R, Sánchez-Céspedes M, Comella JX, Palmer HG, Sánchez de Toledo J, Gallego S, Segura MF.

Oncogene. 2016 Sep 29;35(39):5179-90. doi: 10.1038/onc.2016.50. Epub 2016 Mar 21.

PMID:
26996667
10.

Neurodegeneration and neuroinflammation: two processes, one target.

Carriba P, Comella JX.

Neural Regen Res. 2015 Oct;10(10):1581-3. doi: 10.4103/1673-5374.165269. No abstract available.

11.

Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells.

Urresti J, Ruiz-Meana M, Coccia E, Arévalo JC, Castellano J, Fernández-Sanz C, Galenkamp KM, Planells-Ferrer L, Moubarak RS, Llecha-Cano N, Reix S, García-Dorado D, Barneda-Zahonero B, Comella JX.

J Biol Chem. 2016 Jan 15;291(3):1221-34. doi: 10.1074/jbc.M115.677682. Epub 2015 Nov 18.

12.

FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons.

Bosch C, Martínez A, Masachs N, Teixeira CM, Fernaud I, Ulloa F, Pérez-Martínez E, Lois C, Comella JX, DeFelipe J, Merchán-Pérez A, Soriano E.

Front Neuroanat. 2015 May 21;9:60. doi: 10.3389/fnana.2015.00060. eCollection 2015. Erratum in: Front Neuroanat. 2016 Oct 18;10 :100.

13.

TNFα sensitizes neuroblastoma cells to FasL-, cisplatin- and etoposide-induced cell death by NF-κB-mediated expression of Fas.

Galenkamp KM, Carriba P, Urresti J, Planells-Ferrer L, Coccia E, Lopez-Soriano J, Barneda-Zahonero B, Moubarak RS, Segura MF, Comella JX.

Mol Cancer. 2015 Mar 19;14:62. doi: 10.1186/s12943-015-0329-x.

14.

Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death.

Carriba P, Jimenez S, Navarro V, Moreno-Gonzalez I, Barneda-Zahonero B, Moubarak RS, Lopez-Soriano J, Gutierrez A, Vitorica J, Comella JX.

Cell Death Dis. 2015 Feb 12;6:e1639. doi: 10.1038/cddis.2015.6.

15.

Evaluation of Candidate Genes Related to Neuronal Apoptosis in Late-Onset Alzheimer’s Disease.

Moreno-Grau S, Barneda B, Carriba P, Marín J, Sotolongo-Grau O, Hernández I, Rosende-Roca M, Mauleón A, Vargas L, Espinosa A, Alegret M, Rodriguez O, Ortega G, Fernández MV, López-Arrieta J, Tárraga L, Boada M, Antúnez C, López J, Ruiz A, Comella JX.

J Alzheimers Dis. 2015;45(2):621-9.

PMID:
25613099
16.

Amyloid Beta, TNFα and FAIM-L; Approaching New Therapeutic Strategies for AD.

Carriba P, Comella JX.

Front Neurol. 2014 Dec 18;5:276. doi: 10.3389/fneur.2014.00276. eCollection 2014. No abstract available.

17.

Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe.

Cornago M, Garcia-Alberich C, Blasco-Angulo N, Vall-Llaura N, Nager M, Herreros J, Comella JX, Sanchis D, Llovera M.

Cell Death Dis. 2014 Oct 2;5:e1435. doi: 10.1038/cddis.2014.412.

18.

MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness.

Planells-Ferrer L, Urresti J, Soriano A, Reix S, Murphy DM, Ferreres JC, Borràs F, Gallego S, Stallings RL, Moubarak RS, Segura MF, Comella JX.

Cell Death Dis. 2014 Sep 4;5:e1401. doi: 10.1038/cddis.2014.356.

19.

Activation-induced cell death in T lymphocytes from multiple sclerosis patients.

Moreno M, Negrotto L, Río J, Moubarak R, Martín I, Bustamante MF, Comella JX, Vidal-Jordana A, Pérez-Boza J, Montalban X, Comabella M.

J Neuroimmunol. 2014 Jul 15;272(1-2):51-5. doi: 10.1016/j.jneuroim.2014.04.007. Epub 2014 Apr 16.

20.

FAIM-L is an IAP-binding protein that inhibits XIAP ubiquitinylation and protects from Fas-induced apoptosis.

Moubarak RS, Planells-Ferrer L, Urresti J, Reix S, Segura MF, Carriba P, Marqués-Fernàndez F, Sole C, Llecha-Cano N, Lopez-Soriano J, Sanchis D, Yuste VJ, Comella JX.

J Neurosci. 2013 Dec 4;33(49):19262-75. doi: 10.1523/JNEUROSCI.2479-13.2013.

21.

X-linked inhibitor of apoptosis protein negatively regulates neuronal differentiation through interaction with cRAF and Trk.

Fadó R, Moubarak RS, Miñano-Molina AJ, Barneda-Zahonero B, Valero J, Saura CA, Moran J, Comella JX, Rodríguez-Álvarez J.

Sci Rep. 2013;3:2397. doi: 10.1038/srep02397.

22.

Neurobehavioral characterization of Endonuclease G knockout mice reveals a new putative molecular player in the regulation of anxiety.

Giralt A, Sanchis D, Cherubini M, Ginés S, Cañas X, Comella JX, Alberch J.

Exp Neurol. 2013 Sep;247:122-9. doi: 10.1016/j.expneurol.2013.03.028. Epub 2013 Apr 18.

PMID:
23603365
23.

A role for the tyrosine kinase ACK1 in neurotrophin signaling and neuronal extension and branching.

La Torre A, del Mar Masdeu M, Cotrufo T, Moubarak RS, del Río JA, Comella JX, Soriano E, Ureña JM.

Cell Death Dis. 2013 Apr 18;4:e602. doi: 10.1038/cddis.2013.99.

24.

Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation.

di Penta A, Moreno B, Reix S, Fernandez-Diez B, Villanueva M, Errea O, Escala N, Vandenbroeck K, Comella JX, Villoslada P.

PLoS One. 2013;8(2):e54722. doi: 10.1371/journal.pone.0054722. Epub 2013 Feb 19.

25.

Chromatin collapse during caspase-dependent apoptotic cell death requires DNA fragmentation factor, 40-kDa subunit-/caspase-activated deoxyribonuclease-mediated 3'-OH single-strand DNA breaks.

Iglesias-Guimarais V, Gil-Guiñon E, Sánchez-Osuna M, Casanelles E, García-Belinchón M, Comella JX, Yuste VJ.

J Biol Chem. 2013 Mar 29;288(13):9200-15. doi: 10.1074/jbc.M112.411371. Epub 2013 Feb 21.

26.

A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart.

Ye J, Llorian M, Cardona M, Rongvaux A, Moubarak RS, Comella JX, Bassel-Duby R, Flavell RA, Olson EN, Smith CW, Sanchis D.

J Cell Sci. 2013 Apr 1;126(Pt 7):1682-91. doi: 10.1242/jcs.121384. Epub 2013 Feb 19.

27.

TNFα induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway.

Marques-Fernandez F, Planells-Ferrer L, Gozzelino R, Galenkamp KM, Reix S, Llecha-Cano N, Lopez-Soriano J, Yuste VJ, Moubarak RS, Comella JX.

Cell Death Dis. 2013 Feb 14;4:e493. doi: 10.1038/cddis.2013.25.

28.

NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w.

Casanelles E, Gozzelino R, Marqués-Fernández F, Iglesias-Guimarais V, Garcia-Belinchón M, Sánchez-Osuna M, Solé C, Moubarak RS, Comella JX, Yuste VJ.

Biochim Biophys Acta. 2013 May;1833(5):1085-95. doi: 10.1016/j.bbamcr.2013.01.014. Epub 2013 Jan 28.

29.

Syntaxin 1 is required for DCC/Netrin-1-dependent chemoattraction of migrating neurons from the lower rhombic lip.

Cotrufo T, Andrés RM, Ros O, Pérez-Brangulí F, Muhaisen A, Fuschini G, Martínez R, Pascual M, Comella JX, Soriano E.

Eur J Neurosci. 2012 Nov;36(9):3152-64. doi: 10.1111/j.1460-9568.2012.08259.x. Epub 2012 Sep 4. Erratum in: Eur J Neurosci. 2013 Jul;38(2):2338.

PMID:
22946563
30.

Translation of Myocyte Enhancer Factor-2 is induced by hypertrophic stimuli in cardiomyocytes through a Calcineurin-dependent pathway.

Ye J, Cardona M, Llovera M, Comella JX, Sanchis D.

J Mol Cell Cardiol. 2012 Oct;53(4):578-87. doi: 10.1016/j.yjmcc.2012.07.013. Epub 2012 Jul 28.

PMID:
22850285
31.

Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease.

Iglesias-Guimarais V, Gil-Guiñon E, Gabernet G, García-Belinchón M, Sánchez-Osuna M, Casanelles E, Comella JX, Yuste VJ.

J Biol Chem. 2012 Mar 2;287(10):7766-79. doi: 10.1074/jbc.M111.290718. Epub 2012 Jan 17.

32.

Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.

McDermott-Roe C, Ye J, Ahmed R, Sun XM, Serafín A, Ware J, Bottolo L, Muckett P, Cañas X, Zhang J, Rowe GC, Buchan R, Lu H, Braithwaite A, Mancini M, Hauton D, Martí R, García-Arumí E, Hubner N, Jacob H, Serikawa T, Zidek V, Papousek F, Kolar F, Cardona M, Ruiz-Meana M, García-Dorado D, Comella JX, Felkin LE, Barton PJ, Arany Z, Pravenec M, Petretto E, Sanchis D, Cook SA.

Nature. 2011 Oct 5;478(7367):114-8. doi: 10.1038/nature10490.

33.

Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12.

Badiola N, Penas C, Miñano-Molina A, Barneda-Zahonero B, Fadó R, Sánchez-Opazo G, Comella JX, Sabriá J, Zhu C, Blomgren K, Casas C, Rodríguez-Alvarez J.

Cell Death Dis. 2011 Apr 28;2:e149. doi: 10.1038/cddis.2011.31.

34.

EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes.

Zhang J, Ye J, Altafaj A, Cardona M, Bahi N, Llovera M, Cañas X, Cook SA, Comella JX, Sanchis D.

PLoS One. 2011 Mar 17;6(3):e17998. doi: 10.1371/journal.pone.0017998.

35.

A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by BCL-X(L) Overexpression in motoneurons.

Garcera A, Mincheva S, Gou-Fabregas M, Caraballo-Miralles V, Lladó J, Comella JX, Soler RM.

Neurobiol Dis. 2011 Jun;42(3):415-26. doi: 10.1016/j.nbd.2011.02.003. Epub 2011 Feb 16.

PMID:
21333739
36.

Ubiquitination of TrkA by Nedd4-2 regulates receptor lysosomal targeting and mediates receptor signaling.

Georgieva MV, de Pablo Y, Sanchis D, Comella JX, Llovera M.

J Neurochem. 2011 May;117(3):479-93. doi: 10.1111/j.1471-4159.2011.07218.x. Epub 2011 Mar 15.

37.

The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.

Moubarak RS, Solé C, Pascual M, Gutierrez H, Llovera M, Pérez-García MJ, Gozzelino R, Segura MF, Iglesias-Guimarais V, Reix S, Soler RM, Davies AM, Soriano E, Yuste VJ, Comella JX.

J Neurosci. 2010 Apr 28;30(17):6094-105. doi: 10.1523/JNEUROSCI.0537-10.2010.

38.

Specific vulnerability of mouse spinal cord motoneurons to membrane depolarization.

Gou-Fabregas M, Garcera A, Mincheva S, Perez-Garcia MJ, Comella JX, Soler RM.

J Neurochem. 2009 Sep;110(6):1842-54. doi: 10.1111/j.1471-4159.2009.06278.x. Epub 2009 Jul 13.

39.

Polypyrimidine tract binding proteins (PTB) regulate the expression of apoptotic genes and susceptibility to caspase-dependent apoptosis in differentiating cardiomyocytes.

Zhang J, Bahi N, Llovera M, Comella JX, Sanchis D.

Cell Death Differ. 2009 Nov;16(11):1460-8. doi: 10.1038/cdd.2009.87. Epub 2009 Jul 10.

40.

Activation of caspase-8 by tumour necrosis factor receptor 1 is necessary for caspase-3 activation and apoptosis in oxygen-glucose deprived cultured cortical cells.

Badiola N, Malagelada C, Llecha N, Hidalgo J, Comella JX, Sabriá J, Rodríguez-Alvarez J.

Neurobiol Dis. 2009 Sep;35(3):438-47. doi: 10.1016/j.nbd.2009.06.005. Epub 2009 Jun 23.

PMID:
19555759
41.

Signalling by neurotrophins and hepatocyte growth factor regulates axon morphogenesis by differential beta-catenin phosphorylation.

David MD, Yeramian A, Duñach M, Llovera M, Cantí C, de Herreros AG, Comella JX, Herreros J.

J Cell Sci. 2008 Aug 15;121(Pt 16):2718-30. doi: 10.1242/jcs.029660. Epub 2008 Jul 29.

42.

BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.

Gozzelino R, Sole C, Llecha N, Segura MF, Moubarak RS, Iglesias-Guimarais V, Perez-Garcia MJ, Reix S, Zhang J, Badiola N, Sanchis D, Rodriguez-Alvarez J, Trullas R, Yuste VJ, Comella JX.

Cell Res. 2008 Oct;18(10):1020-36. doi: 10.1038/cr.2008.76.

PMID:
18591962
43.

Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons.

Encinas M, Rozen EJ, Dolcet X, Jain S, Comella JX, Milbrandt J, Johnson EM Jr.

Cell Death Differ. 2008 Sep;15(9):1510-21. doi: 10.1038/cdd.2008.76. Epub 2008 May 23.

44.

Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.

de Pablo Y, Pérez-García MJ, Georgieva MV, Sanchis D, Lindqvist N, Soler RM, Comella JX, Llovera M.

J Neurochem. 2008 Jan;104(1):124-39. doi: 10.1111/j.1471-4159.2007.05027.x.

45.

Neuroprotection by neurotrophic factors and membrane depolarization is regulated by calmodulin kinase IV.

Pérez-García MJ, Gou-Fabregas M, de Pablo Y, Llovera M, Comella JX, Soler RM.

J Biol Chem. 2008 Feb 15;283(7):4133-44. Epub 2007 Dec 13.

46.

Developmental silencing and independency from E2F of apoptotic gene expression in postmitotic tissues.

Zhang J, Bahi N, Zubiaga AM, Comella JX, Llovera M, Sanchis D.

FEBS Lett. 2007 Dec 22;581(30):5781-6. Epub 2007 Nov 26.

47.

An alternative view of apoptosis in heart development and disease.

Sanchis D, Llovera M, Ballester M, Comella JX.

Cardiovasc Res. 2008 Feb 1;77(3):448-51. Epub 2007 Nov 20. No abstract available.

PMID:
18032394
48.

6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA.

Gomez-Lazaro M, Galindo MF, Concannon CG, Segura MF, Fernandez-Gomez FJ, Llecha N, Comella JX, Prehn JH, Jordan J.

J Neurochem. 2008 Mar;104(6):1599-612. Epub 2007 Nov 6.

49.

The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis.

Segura MF, Sole C, Pascual M, Moubarak RS, Perez-Garcia MJ, Gozzelino R, Iglesias V, Badiola N, Bayascas JR, Llecha N, Rodriguez-Alvarez J, Soriano E, Yuste VJ, Comella JX.

J Neurosci. 2007 Oct 17;27(42):11228-41.

50.

Differential, age-dependent MEK-ERK and PI3K-Akt activation by insulin acting as a survival factor during embryonic retinal development.

Chavarría T, Valenciano AI, Mayordomo R, Egea J, Comella JX, Hallböök F, de Pablo F, de la Rosa EJ.

Dev Neurobiol. 2007 Nov;67(13):1777-88.

Supplemental Content

Loading ...
Support Center