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Items: 1 to 50 of 81

1.

Influence of Gut Microbiota on Progression to Tuberculosis Generated by High Fat Diet-Induced Obesity in C3HeB/FeJ Mice.

Arias L, Goig GA, Cardona P, Torres-Puente M, Díaz J, Rosales Y, Garcia E, Tapia G, Comas I, Vilaplana C, Cardona PJ.

Front Immunol. 2019 Oct 18;10:2464. doi: 10.3389/fimmu.2019.02464. eCollection 2019.

2.

High-resolution mapping of tuberculosis transmission: Whole genome sequencing and phylogenetic modelling of a cohort from Valencia Region, Spain.

Xu Y, Cancino-Muñoz I, Torres-Puente M, Villamayor LM, Borrás R, Borrás-Máñez M, Bosque M, Camarena JJ, Colomer-Roig E, Colomina J, Escribano I, Esparcia-Rodríguez O, Gil-Brusola A, Gimeno C, Gimeno-Gascón A, Gomila-Sard B, González-Granda D, Gonzalo-Jiménez N, Guna-Serrano MR, López-Hontangas JL, Martín-González C, Moreno-Muñoz R, Navarro D, Navarro M, Orta N, Pérez E, Prat J, Rodríguez JC, Ruiz-García MM, Vanaclocha H, Colijn C, Comas I.

PLoS Med. 2019 Oct 31;16(10):e1002961. doi: 10.1371/journal.pmed.1002961. eCollection 2019 Oct.

3.

Development and application of affordable SNP typing approaches to genotype Mycobacterium tuberculosis complex strains in low and high burden countries.

Cancino-Muñoz I, Gil-Brusola A, Torres-Puente M, Mariner-Llicer C, Dogba J, Akinseye V, Adesokan K, Kwaghe A, Ejeh F, Cadmus S, Comas I.

Sci Rep. 2019 Oct 25;9(1):15343. doi: 10.1038/s41598-019-51326-2.

4.

Towards next-generation diagnostics for tuberculosis: identification of novel molecular targets by large-scale comparative genomics.

Goig GA, Torres-Puente M, Mariner-Llicer C, Villamayor LM, Chiner-Oms Á, Gil-Brusola A, Borrás R, Comas I.

Bioinformatics. 2019 Oct 3. pii: btz729. doi: 10.1093/bioinformatics/btz729. [Epub ahead of print]

PMID:
31580405
5.

Evolutionary Dissection of the Dot/Icm System Based on Comparative Genomics of 58 Legionella Species.

Gomez-Valero L, Chiner-Oms A, Comas I, Buchrieser C.

Genome Biol Evol. 2019 Sep 1;11(9):2619-2632. doi: 10.1093/gbe/evz186.

6.

Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex.

Chiner-Oms Á, Berney M, Boinett C, González-Candelas F, Young DB, Gagneux S, Jacobs WR Jr, Parkhill J, Cortes T, Comas I.

Nat Commun. 2019 Sep 5;10(1):3994. doi: 10.1038/s41467-019-11948-6.

7.

Genomic determinants of speciation and spread of the Mycobacterium tuberculosis complex.

Chiner-Oms Á, Sánchez-Busó L, Corander J, Gagneux S, Harris SR, Young D, González-Candelas F, Comas I.

Sci Adv. 2019 Jun 12;5(6):eaaw3307. doi: 10.1126/sciadv.aaw3307. eCollection 2019 Jun.

8.

Replay by authors: Serum testosterone level is a useful biomarker for determining the optimal treatment for castration-resistant prostate cancer.

Morote J, Comas I.

Urol Oncol. 2019 Sep;37(9):571. doi: 10.1016/j.urolonc.2019.05.016. Epub 2019 Jun 22. No abstract available.

PMID:
31239185
9.

Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues.

Meehan CJ, Goig GA, Kohl TA, Verboven L, Dippenaar A, Ezewudo M, Farhat MR, Guthrie JL, Laukens K, Miotto P, Ofori-Anyinam B, Dreyer V, Supply P, Suresh A, Utpatel C, van Soolingen D, Zhou Y, Ashton PM, Brites D, Cabibbe AM, de Jong BC, de Vos M, Menardo F, Gagneux S, Gao Q, Heupink TH, Liu Q, Loiseau C, Rigouts L, Rodwell TC, Tagliani E, Walker TM, Warren RM, Zhao Y, Zignol M, Schito M, Gardy J, Cirillo DM, Niemann S, Comas I, Van Rie A.

Nat Rev Microbiol. 2019 Sep;17(9):533-545. doi: 10.1038/s41579-019-0214-5. Review.

PMID:
31209399
10.

Whole genomic sequencing as a tool for diagnosis of drug and multidrug-resistance tuberculosis in an endemic region in Mexico.

Madrazo-Moya CF, Cancino-Muñoz I, Cuevas-Córdoba B, González-Covarrubias V, Barbosa-Amezcua M, Soberón X, Muñiz-Salazar R, Martínez-Guarneros A, Bäcker C, Zarrabal-Meza J, Sampieri-Ramirez C, Enciso-Moreno A, Lauzardo M, Comas I, Zenteno-Cuevas R.

PLoS One. 2019 Jun 5;14(6):e0213046. doi: 10.1371/journal.pone.0213046. eCollection 2019.

11.

Cryptic Resistance Mutations Associated With Misdiagnoses of Multidrug-Resistant Tuberculosis.

Cancino-Muñoz I, Moreno-Molina M, Furió V, Goig GA, Torres-Puente M, Chiner-Oms Á, Villamayor LM, Sanz F, Guna-Serrano MR, Comas I.

J Infect Dis. 2019 Jun 19;220(2):316-320. doi: 10.1093/infdis/jiz104.

12.

Large genomics datasets shed light on the evolution of the Mycobacterium tuberculosis complex.

Chiner-Oms Á, Comas I.

Infect Genet Evol. 2019 Aug;72:10-15. doi: 10.1016/j.meegid.2019.02.028. Epub 2019 Feb 26.

PMID:
30822550
13.

The Future of TB Resistance Diagnosis: The Essentials on Whole Genome Sequencing and Rapid Testing Methods.

Moreno-Molina M, Comas I, Furió V.

Arch Bronconeumol. 2019 Aug;55(8):421-426. doi: 10.1016/j.arbres.2019.01.002. Epub 2019 Feb 20. Review. English, Spanish.

14.

Simplified Model to Survey Tuberculosis Transmission in Countries Without Systematic Molecular Epidemiology Programs.

Domínguez J, Acosta F, Pérez-Lago L, Sambrano D, Batista V, De La Guardia C, Abascal E, Chiner-Oms Á, Comas I, González P, Bravo J, Del Cid P, Rosas S, Muñoz P, Goodridge A, García de Viedma D.

Emerg Infect Dis. 2019 Mar;25(3):507-514. doi: 10.3201/eid2503.181593.

15.

Whole genome sequencing-based analysis of tuberculosis (TB) in migrants: rapid tools for cross-border surveillance and to distinguish between recent transmission in the host country and new importations.

Abascal E, Pérez-Lago L, Martínez-Lirola M, Chiner-Oms Á, Herranz M, Chaoui I, Comas I, El Messaoudi MD, Cárdenas JAG, Santantón S, Bouza E, García-de-Viedma D.

Euro Surveill. 2019 Jan;24(4). doi: 10.2807/1560-7917.ES.2019.24.4.1800005.

16.

China's tuberculosis epidemic stems from historical expansion of four strains of Mycobacterium tuberculosis.

Liu Q, Ma A, Wei L, Pang Y, Wu B, Luo T, Zhou Y, Zheng HX, Jiang Q, Gan M, Zuo T, Liu M, Yang C, Jin L, Comas I, Gagneux S, Zhao Y, Pepperell CS, Gao Q.

Nat Ecol Evol. 2018 Dec;2(12):1982-1992. doi: 10.1038/s41559-018-0680-6. Epub 2018 Nov 5.

17.

Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase.

Ezewudo M, Borens A, Chiner-Oms Á, Miotto P, Chindelevitch L, Starks AM, Hanna D, Liwski R, Zignol M, Gilpin C, Niemann S, Kohl TA, Warren RM, Crook D, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler DM, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, McNerney R, Cirillo DM, Schito M, Rodwell TC, Posey J.

Sci Rep. 2018 Oct 18;8(1):15382. doi: 10.1038/s41598-018-33731-1.

18.

Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing.

CRyPTIC Consortium and the 100,000 Genomes Project, Allix-Béguec C, Arandjelovic I, Bi L, Beckert P, Bonnet M, Bradley P, Cabibbe AM, Cancino-Muñoz I, Caulfield MJ, Chaiprasert A, Cirillo DM, Clifton DA, Comas I, Crook DW, De Filippo MR, de Neeling H, Diel R, Drobniewski FA, Faksri K, Farhat MR, Fleming J, Fowler P, Fowler TA, Gao Q, Gardy J, Gascoyne-Binzi D, Gibertoni-Cruz AL, Gil-Brusola A, Golubchik T, Gonzalo X, Grandjean L, He G, Guthrie JL, Hoosdally S, Hunt M, Iqbal Z, Ismail N, Johnston J, Khanzada FM, Khor CC, Kohl TA, Kong C, Lipworth S, Liu Q, Maphalala G, Martinez E, Mathys V, Merker M, Miotto P, Mistry N, Moore DAJ, Murray M, Niemann S, Omar SV, Ong RT, Peto TEA, Posey JE, Prammananan T, Pym A, Rodrigues C, Rodrigues M, Rodwell T, Rossolini GM, Sánchez Padilla E, Schito M, Shen X, Shendure J, Sintchenko V, Sloutsky A, Smith EG, Snyder M, Soetaert K, Starks AM, Supply P, Suriyapol P, Tahseen S, Tang P, Teo YY, Thuong TNT, Thwaites G, Tortoli E, van Soolingen D, Walker AS, Walker TM, Wilcox M, Wilson DJ, Wyllie D, Yang Y, Zhang H, Zhao Y, Zhu B.

N Engl J Med. 2018 Oct 11;379(15):1403-1415. doi: 10.1056/NEJMoa1800474. Epub 2018 Sep 26.

19.

TB Transmission: Closing the Gaps.

Comas I, Gardy JL.

EBioMedicine. 2018 Aug;34:4-5. doi: 10.1016/j.ebiom.2018.07.020. Epub 2018 Jul 30. No abstract available.

20.

Whole-genome sequence analysis of the Mycobacterium avium complex and proposal of the transfer of Mycobacterium yongonense to Mycobacterium intracellulare subsp. yongonense subsp. nov.

Castejon M, Menéndez MC, Comas I, Vicente A, Garcia MJ.

Int J Syst Evol Microbiol. 2018 Jun;68(6):1998-2005. doi: 10.1099/ijsem.0.002767. Epub 2018 Apr 23.

PMID:
29683417
21.

Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity.

Chiner-Oms Á, González-Candelas F, Comas I.

Sci Rep. 2018 Feb 28;8(1):3813. doi: 10.1038/s41598-018-22237-5.

22.
23.

Mycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts.

Herranz M, Pole I, Ozere I, Chiner-Oms Á, Martínez-Lirola M, Pérez-García F, Gijón P, Serrano MJR, Romero LC, Cuevas O, Comas I, Bouza E, Pérez-Lago L, García-de-Viedma D.

Front Microbiol. 2018 Jan 19;8:2661. doi: 10.3389/fmicb.2017.02661. eCollection 2017.

24.

The Troika Host-Pathogen-Extrinsic Factors in Tuberculosis: Modulating Inflammation and Clinical Outcomes.

Bastos HN, Osório NS, Gagneux S, Comas I, Saraiva M.

Front Immunol. 2018 Jan 9;8:1948. doi: 10.3389/fimmu.2017.01948. eCollection 2017. Review.

25.

A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis.

Miotto P, Tessema B, Tagliani E, Chindelevitch L, Starks AM, Emerson C, Hanna D, Kim PS, Liwski R, Zignol M, Gilpin C, Niemann S, Denkinger CM, Fleming J, Warren RM, Crook D, Posey J, Gagneux S, Hoffner S, Rodrigues C, Comas I, Engelthaler DM, Murray M, Alland D, Rigouts L, Lange C, Dheda K, Hasan R, Ranganathan UDK, McNerney R, Ezewudo M, Cirillo DM, Schito M, Köser CU, Rodwell TC.

Eur Respir J. 2017 Dec 28;50(6). pii: 1701354. doi: 10.1183/13993003.01354-2017. Print 2017 Dec.

26.

Serum Testosterone Levels in Prostate Cancer Patients Undergoing Luteinizing Hormone-Releasing Hormone Agonist Therapy.

Morote J, Comas I, Planas J, Maldonado X, Celma A, Placer J, Ferrer R, Carles J, Regis L.

Clin Genitourin Cancer. 2018 Apr;16(2):e491-e496. doi: 10.1016/j.clgc.2017.10.025. Epub 2017 Dec 2.

PMID:
29198640
27.

Genomic Epidemiology of Tuberculosis.

Comas I.

Adv Exp Med Biol. 2017;1019:79-93. doi: 10.1007/978-3-319-64371-7_4. Review.

PMID:
29116630
28.

Accuracy of serum luteinizing hormone and serum testosterone measurements to assess the efficacy of medical castration in prostate cancer patients.

Morote J, Comas I, Ferrer R, Planas J, Celma A, Regis L.

J Biomed Sci. 2017 Oct 22;24(1):81. doi: 10.1186/s12929-017-0386-0.

29.

In-Depth Characterization and Functional Analysis of Clonal Variants in a Mycobacterium tuberculosis Strain Prone to Microevolution.

Navarro Y, Pérez-Lago L, Herranz M, Sierra O, Comas I, Sicilia J, Bouza E, García de Viedma D.

Front Microbiol. 2017 Apr 24;8:694. doi: 10.3389/fmicb.2017.00694. eCollection 2017.

30.

A systematic review of methods for quantifying serum testosterone in patients with prostate cancer who underwent castration.

Comas I, Ferrer R, Planas J, Celma A, Regis L, Morote J.

Actas Urol Esp. 2018 Mar;42(2):86-93. doi: 10.1016/j.acuro.2017.01.007. Epub 2017 Mar 2. English, Spanish.

PMID:
28259362
31.

The effect size of type 2 diabetes mellitus on tuberculosis drug resistance and adverse treatment outcomes.

Perez-Navarro LM, Restrepo BI, Fuentes-Dominguez FJ, Duggirala R, Morales-Romero J, López-Alvarenga JC, Comas I, Zenteno-Cuevas R.

Tuberculosis (Edinb). 2017 Mar;103:83-91. doi: 10.1016/j.tube.2017.01.006. Epub 2017 Jan 24.

PMID:
28237037
32.

New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles.

Coppola M, van Meijgaarden KE, Franken KL, Commandeur S, Dolganov G, Kramnik I, Schoolnik GK, Comas I, Lund O, Prins C, van den Eeden SJ, Korsvold GE, Oftung F, Geluk A, Ottenhoff TH.

Sci Rep. 2016 Nov 28;6:37793. doi: 10.1038/srep37793.

33.

Adiponectin, Leptin and Inflammatory Markers in HIV-associated Metabolic Syndrome in Children and Adolescents.

Espiau M, Yeste D, Noguera-Julian A, Soler-Palacín P, Fortuny C, Ferrer R, Comas I, Martín-Nalda A, Deyà-Martínez Á, Figueras C, Carrascosa A.

Pediatr Infect Dis J. 2017 Feb;36(2):e31-e37. doi: 10.1097/INF.0000000000001394.

PMID:
27832021
34.

Free Testosterone During Androgen Deprivation Therapy Predicts Castration-Resistant Progression Better Than Total Testosterone.

Regis L, Planas J, Carles J, Maldonado X, Comas I, Ferrer R, Morote J.

Prostate. 2017 Jan;77(1):114-120. doi: 10.1002/pros.23256. Epub 2016 Nov 1.

PMID:
27800640
35.

Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages.

Stucki D, Brites D, Jeljeli L, Coscolla M, Liu Q, Trauner A, Fenner L, Rutaihwa L, Borrell S, Luo T, Gao Q, Kato-Maeda M, Ballif M, Egger M, Macedo R, Mardassi H, Moreno M, Tudo Vilanova G, Fyfe J, Globan M, Thomas J, Jamieson F, Guthrie JL, Asante-Poku A, Yeboah-Manu D, Wampande E, Ssengooba W, Joloba M, Henry Boom W, Basu I, Bower J, Saraiva M, Vaconcellos SEG, Suffys P, Koch A, Wilkinson R, Gail-Bekker L, Malla B, Ley SD, Beck HP, de Jong BC, Toit K, Sanchez-Padilla E, Bonnet M, Gil-Brusola A, Frank M, Penlap Beng VN, Eisenach K, Alani I, Wangui Ndung'u P, Revathi G, Gehre F, Akter S, Ntoumi F, Stewart-Isherwood L, Ntinginya NE, Rachow A, Hoelscher M, Cirillo DM, Skenders G, Hoffner S, Bakonyte D, Stakenas P, Diel R, Crudu V, Moldovan O, Al-Hajoj S, Otero L, Barletta F, Jane Carter E, Diero L, Supply P, Comas I, Niemann S, Gagneux S.

Nat Genet. 2016 Dec;48(12):1535-1543. doi: 10.1038/ng.3704. Epub 2016 Oct 31.

36.

Behavior of chemiluminescent assays to measure serum testosterone during androgen deprivation therapy.

Morote J, Comas I, Planas J, Celma A, Ferrer R, Regis L.

Int J Urol. 2016 Nov;23(11):957-958. doi: 10.1111/iju.13180. Epub 2016 Aug 3. No abstract available.

37.

A novel strategy based on genomics and specific PCR reveals how a multidrug-resistant Mycobacterium tuberculosis strain became prevalent in Equatorial Guinea 15 years after its emergence.

Pérez-Lago L, Izco S, Herranz M, Tudó G, Carcelén M, Comas I, Sierra O, González-Martín J, Ruiz-Serrano MJ, Eyene J, Bouza E, García de Viedma D.

Clin Microbiol Infect. 2017 Feb;23(2):92-97. doi: 10.1016/j.cmi.2016.10.006. Epub 2016 Oct 13.

38.

Urgent Implementation in a Hospital Setting of a Strategy To Rule Out Secondary Cases Caused by Imported Extensively Drug-Resistant Mycobacterium tuberculosis Strains at Diagnosis.

Pérez-Lago L, Martínez-Lirola M, García S, Herranz M, Mokrousov I, Comas I, Martínez-Priego L, Bouza E, García-de-Viedma D.

J Clin Microbiol. 2016 Dec;54(12):2969-2974. Epub 2016 Sep 28.

39.

[Next generation sequencing for the diagnostics and epidemiology of tuberculosis].

Comas I, Gil A.

Enferm Infecc Microbiol Clin. 2016 Jul;34 Suppl 3:32-9. doi: 10.1016/S0213-005X(16)30217-8. Review. Spanish.

PMID:
27474245
40.

Subtle genotypic changes can be observed soon after diagnosis in Mycobacterium tuberculosis infection.

Pérez-Lago L, Rodríguez Borlado AI, Comas I, Herranz M, Ruiz-Serrano MJ, Bouza E, García-de-Viedma D.

Int J Med Microbiol. 2016 Sep;306(6):401-5. doi: 10.1016/j.ijmm.2016.05.007. Epub 2016 May 16.

PMID:
27247102
41.

Draft Genome Sequence of Mycobacterium brumae ATCC 51384.

D'Auria G, Torrents E, Luquin M, Comas I, Julián E.

Genome Announc. 2016 Apr 28;4(2). pii: e00237-16. doi: 10.1128/genomeA.00237-16.

42.

Legionella effectors reflect strength in diversity.

Comas I.

Nat Genet. 2016 Feb;48(2):115-6. doi: 10.1038/ng.3492.

PMID:
26813764
43.

Ultrafast Assessment of the Presence of a High-Risk Mycobacterium tuberculosis Strain in a Population.

Pérez-Lago L, Herranz M, Comas I, Ruiz-Serrano MJ, López Roa P, Bouza E, García-de-Viedma D.

J Clin Microbiol. 2016 Mar;54(3):779-81. doi: 10.1128/JCM.02851-15. Epub 2015 Dec 30.

44.

Population Genomics of Mycobacterium tuberculosis in Ethiopia Contradicts the Virgin Soil Hypothesis for Human Tuberculosis in Sub-Saharan Africa.

Comas I, Hailu E, Kiros T, Bekele S, Mekonnen W, Gumi B, Tschopp R, Ameni G, Hewinson RG, Robertson BD, Goig GA, Stucki D, Gagneux S, Aseffa A, Young D, Berg S.

Curr Biol. 2015 Dec 21;25(24):3260-6. doi: 10.1016/j.cub.2015.10.061. Epub 2015 Dec 10.

45.

Persistent Infection by a Mycobacterium tuberculosis Strain That Was Theorized To Have Advantageous Properties, as It Was Responsible for a Massive Outbreak.

Pérez-Lago L, Navarro Y, Montilla P, Comas I, Herranz M, Rodríguez-Gallego C, Ruiz Serrano MJ, Bouza E, García de Viedma D.

J Clin Microbiol. 2015 Nov;53(11):3423-9. doi: 10.1128/JCM.01405-15. Epub 2015 Aug 12.

46.

Southern East Asian origin and coexpansion of Mycobacterium tuberculosis Beijing family with Han Chinese.

Luo T, Comas I, Luo D, Lu B, Wu J, Wei L, Yang C, Liu Q, Gan M, Sun G, Shen X, Liu F, Gagneux S, Mei J, Lan R, Wan K, Gao Q.

Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):8136-41. doi: 10.1073/pnas.1424063112. Epub 2015 Jun 15.

47.

Phylogenetic analysis of vitamin B12-related metabolism in Mycobacterium tuberculosis.

Young DB, Comas I, de Carvalho LP.

Front Mol Biosci. 2015 Mar 4;2:6. doi: 10.3389/fmolb.2015.00006. eCollection 2015. Review.

48.

Draft Genome Sequences of Mycobacterium setense Type Strain DSM-45070 and the Nonpathogenic Strain Manresensis, Isolated from the Bank of the Cardener River in Manresa, Catalonia, Spain.

Rech G, Vilaplana C, Velasco J, Pluvinet R, Santín S, Prat C, Julián E, Alcaide F, Comas I, Sumoy L, Cardona PJ.

Genome Announc. 2015 Feb 5;3(1). pii: e01485-14. doi: 10.1128/genomeA.01485-14.

49.

Fast and low-cost decentralized surveillance of transmission of tuberculosis based on strain-specific PCRs tailored from whole genome sequencing data: a pilot study.

Pérez-Lago L, Martínez Lirola M, Herranz M, Comas I, Bouza E, García-de-Viedma D.

Clin Microbiol Infect. 2015 Mar;21(3):249.e1-9. doi: 10.1016/j.cmi.2014.10.003. Epub 2014 Oct 29.

50.

[Molecular epidemiology studies on the immigrant population in Spain].

González-Candelas F, Alma Bracho M, Comas I, d'Auria G, D Unková M, García R, Gosalbes MJ, Isaac S, Latorre A, López-Labrador FX, Patiño Galindo JÁ, Palero F, Pérez-Brocal V, Pérez-Cobas AE, Sánchez-Busó L, Silva FJ, Vázquez-Castellanos JF, Moya A.

Rev Esp Salud Publica. 2014 Nov-Dec;88(6):819-28. doi: 10.4321/S1135-57272014000600013. Review. Spanish.

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