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Items: 1 to 50 of 59

1.

Myeloid p38α signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis.

Youssif C, Cubillos-Rojas M, Comalada M, Llonch E, Perna C, Djouder N, Nebreda AR.

EMBO Mol Med. 2018 Jul;10(7). pii: e8403. doi: 10.15252/emmm.201708403.

2.

Modulation of Human Peripheral Blood Mononuclear Cell Signaling by Medicinal Cannabinoids.

Utomo WK, de Vries M, Braat H, Bruno MJ, Parikh K, Comalada M, Peppelenbosch MP, van Goor H, Fuhler GM.

Front Mol Neurosci. 2017 Jan 24;10:14. doi: 10.3389/fnmol.2017.00014. eCollection 2017.

3.
4.

The viability of Lactobacillus fermentum CECT5716 is not essential to exert intestinal anti-inflammatory properties.

Rodríguez-Nogales A, Algieri F, Vezza T, Garrido-Mesa N, Olivares M, Comalada M, Riccardi C, Utrilla MP, Rodríguez-Cabezas ME, Galvez J.

Food Funct. 2015 Apr;6(4):1176-84. doi: 10.1039/c4fo00938j.

PMID:
25700085
5.

Active colitis exacerbates immune response to internalized food antigens in mice.

Cueto-Sola M, Bailon E, Utrilla P, Rodríguez-Ruiz J, Garrido-Mesa N, Zarzuelo A, Xaus J, Gálvez J, Comalada M.

Int Arch Allergy Immunol. 2013;162(3):214-24. doi: 10.1159/000353596. Epub 2013 Sep 6.

PMID:
24021980
6.

Deacetylation of C/EBPβ is required for IL-4-induced arginase-1 expression in murine macrophages.

Serrat N, Pereira-Lopes S, Comalada M, Lloberas J, Celada A.

Eur J Immunol. 2012 Nov;42(11):3028-37. doi: 10.1002/eji.201242413. Epub 2012 Sep 20.

7.

MKP-1: a critical phosphatase in the biology of macrophages controlling the switch between proliferation and activation.

Comalada M, Lloberas J, Celada A.

Eur J Immunol. 2012 Aug;42(8):1938-48. doi: 10.1002/eji.201242441. Review.

8.

A shorter and more specific oral sensitization-based experimental model of food allergy in mice.

Bailón E, Cueto-Sola M, Utrilla P, Rodríguez-Ruiz J, Garrido-Mesa N, Zarzuelo A, Xaus J, Gálvez J, Comalada M.

J Immunol Methods. 2012 Jul 31;381(1-2):41-9. doi: 10.1016/j.jim.2012.04.007. Epub 2012 Apr 20.

PMID:
22542400
9.

Arginine and macrophage activation.

Comalada M, Yeramian A, Modolell M, Lloberas J, Celada A.

Methods Mol Biol. 2012;844:223-35. doi: 10.1007/978-1-61779-527-5_16.

PMID:
22262446
10.

The association of minocycline and the probiotic Escherichia coli Nissle 1917 results in an additive beneficial effect in a DSS model of reactivated colitis in mice.

Garrido-Mesa N, Utrilla P, Comalada M, Zorrilla P, Garrido-Mesa J, Zarzuelo A, Rodríguez-Cabezas ME, Gálvez J.

Biochem Pharmacol. 2011 Dec 15;82(12):1891-900. doi: 10.1016/j.bcp.2011.09.004. Epub 2011 Sep 16.

PMID:
21930116
11.

DNFB-DNS hapten-induced colitis in mice should not be considered a model of inflammatory bowel disease.

Bailón E, Cueto-Sola M, Utrilla P, Nieto A, Garrido-Mesa N, Celada A, Zarzuelo A, Xaus J, Gálvez J, Comalada M.

Inflamm Bowel Dis. 2011 Oct;17(10):2087-101. doi: 10.1002/ibd.21586. Epub 2010 Dec 22.

PMID:
21910170
12.

The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis.

Camuesco D, Rodríguez-Cabezas ME, Garrido-Mesa N, Cueto-Sola M, Bailón E, Comalada M, Arribas B, Merlos M, Balsa D, Zarzuelo A, Janer G, Xaus J, Román J, Gálvez J.

Br J Pharmacol. 2012 Feb;165(3):729-40. doi: 10.1111/j.1476-5381.2011.01598.x.

13.

The immunomodulatory properties of viable Lactobacillus salivarius ssp. salivarius CECT5713 are not restricted to the large intestine.

Arribas B, Garrido-Mesa N, Perán L, Camuesco D, Comalada M, Bailón E, Olivares M, Xaus J, Kruidenier L, Sanderson IR, Zarzuelo A, Rodríguez-Cabezas ME, Gálvez J.

Eur J Nutr. 2012 Apr;51(3):365-74. doi: 10.1007/s00394-011-0221-4. Epub 2011 Jun 19.

PMID:
21688122
14.

The intestinal anti-inflammatory effect of minocycline in experimental colitis involves both its immunomodulatory and antimicrobial properties.

Garrido-Mesa N, Camuesco D, Arribas B, Comalada M, Bailón E, Cueto-Sola M, Utrilla P, Nieto A, Zarzuelo A, Rodríguez-Cabezas ME, Gálvez J.

Pharmacol Res. 2011 Apr;63(4):308-19. doi: 10.1016/j.phrs.2010.12.011. Epub 2010 Dec 28.

PMID:
21193045
15.

Cell death, it always matters.

Comalada M, Serrat N, Xaus J.

J Leukoc Biol. 2010 Dec;88(6):1063-4; author reply 1065-6. doi: 10.1189/jlb.0710401. No abstract available.

PMID:
21123293
16.

Macrophage proinflammatory activation and deactivation: a question of balance.

Valledor AF, Comalada M, Santamaría-Babi LF, Lloberas J, Celada A.

Adv Immunol. 2010;108:1-20. doi: 10.1016/B978-0-12-380995-7.00001-X. Review.

PMID:
21056727
17.

The combination of fructooligosaccharides and resistant starch shows prebiotic additive effects in rats.

Rodríguez-Cabezas ME, Camuesco D, Arribas B, Garrido-Mesa N, Comalada M, Bailón E, Cueto-Sola M, Utrilla P, Guerra-Hernández E, Pérez-Roca C, Gálvez J, Zarzuelo A.

Clin Nutr. 2010 Dec;29(6):832-9. doi: 10.1016/j.clnu.2010.05.005. Epub 2010 Jun 1.

PMID:
20605664
18.

Butyrate in vitro immune-modulatory effects might be mediated through a proliferation-related induction of apoptosis.

Bailón E, Cueto-Sola M, Utrilla P, Rodríguez-Cabezas ME, Garrido-Mesa N, Zarzuelo A, Xaus J, Gálvez J, Comalada M.

Immunobiology. 2010 Nov;215(11):863-73. doi: 10.1016/j.imbio.2010.01.001. Epub 2010 Jan 13.

PMID:
20149475
19.

A probiotic strain of Escherichia coli, Nissle 1917, given orally exerts local and systemic anti-inflammatory effects in lipopolysaccharide-induced sepsis in mice.

Arribas B, Rodríguez-Cabezas ME, Camuesco D, Comalada M, Bailón E, Utrilla P, Nieto A, Concha A, Zarzuelo A, Gálvez J.

Br J Pharmacol. 2009 Jul;157(6):1024-33. doi: 10.1111/j.1476-5381.2009.00270.x. Epub 2009 May 26.

20.

The new salicylate derivative UR-1505 modulates the Th2/humoral response in a dextran sodium sulphate model of colitis that resembles ulcerative colitis.

Bailón E, Román J, Ramis I, Michelena P, Balsa D, Merlos M, Zarzuelo A, Gálvez J, Comalada M.

J Pharmacol Sci. 2009 Feb;109(2):315-8.

21.

Role of neutrophil recruitment in the amelioration of experimental colitis by genetic ablation of interleukin-21.

Comalada M, Peppelenbosch MP.

Gastroenterology. 2008 Oct;135(4):1426; author reply 1426-7. doi: 10.1053/j.gastro.2008.06.093. Epub 2008 Sep 5. No abstract available.

PMID:
18775717
22.

IFN-{gamma}-mediated inhibition of MAPK phosphatase expression results in prolonged MAPK activity in response to M-CSF and inhibition of proliferation.

Valledor AF, Arpa L, Sánchez-Tilló E, Comalada M, Casals C, Xaus J, Caelles C, Lloberas J, Celada A.

Blood. 2008 Oct 15;112(8):3274-82. doi: 10.1182/blood-2007-11-123604. Epub 2008 Aug 5.

PMID:
18682602
23.

Evaluation of the preventative effects exerted by Lactobacillus fermentum in an experimental model of septic shock induced in mice.

Arribas B, Rodríguez-Cabezas ME, Comalada M, Bailón E, Camuesco D, Olivares M, Xaus J, Zarzuelo A, Gálvez J.

Br J Nutr. 2009 Jan;101(1):51-8. doi: 10.1017/S0007114508986876. Epub 2008 Apr 29.

PMID:
18445307
24.

Dietary eicosapentaenoic acid and docosahexaenoic acid equally incorporate as decosahexaenoic acid but differ in inflammatory effects.

Sierra S, Lara-Villoslada F, Comalada M, Olivares M, Xaus J.

Nutrition. 2008 Mar;24(3):245-54. doi: 10.1016/j.nut.2007.11.005.

PMID:
18312787
25.

UR-1505, a salicylate able to selectively block T-cell activation, shows intestinal anti-inflammatory activity in the chronic phase of the DSS model of rat colitis.

Bailón E, Comalada M, Román J, Michelena P, Ramis I, Merlos M, Nieto A, Concha A, Zarzuelo A, Gálvez J.

Inflamm Bowel Dis. 2008 Jul;14(7):888-97. doi: 10.1002/ibd.20381.

PMID:
18253952
26.

A comparative study of the preventative effects exerted by three probiotics, Bifidobacterium lactis, Lactobacillus casei and Lactobacillus acidophilus, in the TNBS model of rat colitis.

Peran L, Camuesco D, Comalada M, Bailon E, Henriksson A, Xaus J, Zarzuelo A, Galvez J.

J Appl Microbiol. 2007 Oct;103(4):836-44.

27.

The intestinal anti-inflammatory effects of the novel agent UR-1505 in the TNBS model of rat colitis are mediated by T-lymphocyte inhibition.

Bailón E, Camuesco D, Nieto A, Concha A, Fernández de Arriba A, Román J, Ramis I, Merlos M, Zarzuelo A, Gálvez J, Comalada M.

Biochem Pharmacol. 2007 Nov 15;74(10):1496-506. Epub 2007 Jul 22.

PMID:
17720145
28.

UR-1505, a new salicylate, blocks T cell activation through nuclear factor of activated T cells.

Román J, de Arriba AF, Barrón S, Michelena P, Giral M, Merlos M, Bailón E, Comalada M, Gálvez J, Zarzuelo A, Ramis I.

Mol Pharmacol. 2007 Aug;72(2):269-79. Epub 2007 May 2.

PMID:
17475810
29.

JNK1 Is required for the induction of Mkp1 expression in macrophages during proliferation and lipopolysaccharide-dependent activation.

Sánchez-Tilló E, Comalada M, Xaus J, Farrera C, Valledor AF, Caelles C, Lloberas J, Celada A.

J Biol Chem. 2007 Apr 27;282(17):12566-73. Epub 2007 Mar 2.

30.

Dietary fish oil n-3 fatty acids increase regulatory cytokine production and exert anti-inflammatory effects in two murine models of inflammation.

Sierra S, Lara-Villoslada F, Comalada M, Olivares M, Xaus J.

Lipids. 2006 Dec;41(12):1115-25.

PMID:
17269557
31.

A comparative study of the preventative effects exerted by two probiotics, Lactobacillus reuteri and Lactobacillus fermentum, in the trinitrobenzenesulfonic acid model of rat colitis.

Peran L, Sierra S, Comalada M, Lara-Villoslada F, Bailón E, Nieto A, Concha A, Olivares M, Zarzuelo A, Xaus J, Gálvez J.

Br J Nutr. 2007 Jan;97(1):96-103.

32.

Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship.

Comalada M, Ballester I, Bailón E, Sierra S, Xaus J, Gálvez J, de Medina FS, Zarzuelo A.

Biochem Pharmacol. 2006 Oct 16;72(8):1010-21. Epub 2006 Aug 24.

PMID:
16934226
33.

Cyclophilin A is required for M-CSF-dependent macrophage proliferation.

Sànchez-Tilló E, Wojciechowska M, Comalada M, Farrera C, Lloberas J, Celada A.

Eur J Immunol. 2006 Sep;36(9):2515-24.

34.

Impaired innate immunity in Crohn's disease.

Comalada M, Peppelenbosch MP.

Trends Mol Med. 2006 Sep;12(9):397-9. Epub 2006 Aug 4.

PMID:
16890491
35.

Short-chain fructooligosaccharides, in spite of being fermented in the upper part of the large intestine, have anti-inflammatory activity in the TNBS model of colitis.

Lara-Villoslada F, de Haro O, Camuesco D, Comalada M, Velasco J, Zarzuelo A, Xaus J, Galvez J.

Eur J Nutr. 2006 Oct;45(7):418-25. Epub 2006 Jul 26. Erratum in: Eur J Nutr. 2006 Oct;45(7):425.

PMID:
16871370
36.

The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype.

Comalada M, Bailón E, de Haro O, Lara-Villoslada F, Xaus J, Zarzuelo A, Gálvez J.

J Cancer Res Clin Oncol. 2006 Aug;132(8):487-97. Epub 2006 May 17. Erratum in: J Cancer Res Clin Oncol. 2007 Mar;133(3):211.

PMID:
16788843
37.
38.

Intestinal anti-inflammatory activity of combined quercitrin and dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, in rats with DSS-induced colitis.

Camuesco D, Comalada M, Concha A, Nieto A, Sierra S, Xaus J, Zarzuelo A, Gálvez J.

Clin Nutr. 2006 Jun;25(3):466-76. Epub 2006 May 15.

PMID:
16698151
39.

Granulocyte-macrophage colony-stimulating factor increases L-arginine transport through the induction of CAT2 in bone marrow-derived macrophages.

Martín L, Comalada M, Marti L, Closs EI, MacLeod CL, Martín del Río R, Zorzano A, Modolell M, Celada A, Palacín M, Bertran J.

Am J Physiol Cell Physiol. 2006 May;290(5):C1364-72. Epub 2005 Dec 21.

40.

Preventative effects of a probiotic, Lactobacillus salivarius ssp. salivarius, in the TNBS model of rat colitis.

Peran L, Camuesco D, Comalada M, Nieto A, Concha A, Diaz-Ropero MP, Olivares M, Xaus J, Zarzuelo A, Galvez J.

World J Gastroenterol. 2005 Sep 7;11(33):5185-92.

41.

Lactobacillus fermentum, a probiotic capable to release glutathione, prevents colonic inflammation in the TNBS model of rat colitis.

Peran L, Camuesco D, Comalada M, Nieto A, Concha A, Adrio JL, Olivares M, Xaus J, Zarzuelo A, Galvez J.

Int J Colorectal Dis. 2006 Dec;21(8):737-46. Epub 2005 Jul 29.

PMID:
16052308
42.

Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis.

Camuesco D, Gálvez J, Nieto A, Comalada M, Rodríguez-Cabezas ME, Concha A, Xaus J, Zarzuelo A.

J Nutr. 2005 Apr;135(4):687-94.

PMID:
15795419
43.

Preventative effects of lactulose in the trinitrobenzenesulphonic acid model of rat colitis.

Camuesco D, Peran L, Comalada M, Nieto A, Di Stasi LC, Rodriguez-Cabezas ME, Concha A, Zarzuelo A, Galvez J.

Inflamm Bowel Dis. 2005 Mar;11(3):265-71.

PMID:
15735433
44.

In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway.

Comalada M, Camuesco D, Sierra S, Ballester I, Xaus J, Gálvez J, Zarzuelo A.

Eur J Immunol. 2005 Feb;35(2):584-92.

45.

The intestinal anti-inflammatory effect of quercitrin is associated with an inhibition in iNOS expression.

Camuesco D, Comalada M, Rodríguez-Cabezas ME, Nieto A, Lorente MD, Concha A, Zarzuelo A, Gálvez J.

Br J Pharmacol. 2004 Dec;143(7):908-18. Epub 2004 Nov 8.

48.

High expression of p21 Waf1 in sarcoid granulomas: a putative role for long-lasting inflammation.

Xaus J, Besalduch N, Comalada M, Marcoval J, Pujol R, Mañá J, Celada A.

J Leukoc Biol. 2003 Aug;74(2):295-301.

PMID:
12885947
49.

PKC epsilon is involved in JNK activation that mediates LPS-induced TNF-alpha, which induces apoptosis in macrophages.

Comalada M, Xaus J, Valledor AF, López-López C, Pennington DJ, Celada A.

Am J Physiol Cell Physiol. 2003 Nov;285(5):C1235-45. Epub 2003 Jul 16.

50.

Decorin reverses the repressive effect of autocrine-produced TGF-beta on mouse macrophage activation.

Comalada M, Cardó M, Xaus J, Valledor AF, Lloberas J, Ventura F, Celada A.

J Immunol. 2003 May 1;170(9):4450-6.

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