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Predictors of intracranial hypertension in children undergoing ICP monitoring after severe traumatic brain injury.

Miles DK, Ponisio MR, Colvin R, Limbrick D, Greenberg JK, Brancato C, Leonard JR, Pineda JA.

Childs Nerv Syst. 2020 Jan 22. doi: 10.1007/s00381-020-04516-7. [Epub ahead of print]


Platelet thrombus formation in eHUS is prevented by anti-MBL2.

Kushak RI, Boyle DC, Rosales IA, Ingelfinger JR, Stahl GL, Ozaki M, Colvin RB, Grabowski EF.

PLoS One. 2019 Dec 27;14(12):e0220483. doi: 10.1371/journal.pone.0220483. eCollection 2019.


Long-term Kinetics of Intragraft Gene Signatures in Renal Allograft Tolerance Induced by Transient Mixed Chimerism.

Matsunami M, Rosales IA, Adam BA, Oura T, Mengel M, Smith RN, Lee H, Cosimi AB, Colvin RB, Kawai T.

Transplantation. 2019 Nov;103(11):e334-e344. doi: 10.1097/TP.0000000000002911.


Undifferentiated Abdominal Pain in Children Presenting to the Pediatric Emergency Department.

Harris BR, Chinta SS, Colvin R, Schnadower D, Tarr PI, Sayuk GS.

Clin Pediatr (Phila). 2019 Oct;58(11-12):1212-1223. doi: 10.1177/0009922819867459. Epub 2019 Aug 6.


The pathology of solid organ xenotransplantation.

Rosales IA, Colvin RB.

Curr Opin Organ Transplant. 2019 Oct;24(5):535-542. doi: 10.1097/MOT.0000000000000681.


Nonvascularized human skin chronic allograft rejection.

Rotman S, Koch N, Wiesner L, Aubert V, Rosales IA, Colvin RB, Raffoul W, Pascual M.

Am J Transplant. 2019 Nov;19(11):3191-3196. doi: 10.1111/ajt.15542. Epub 2019 Aug 13.


Plasmacytoid Dendritic Cell-driven Induction of Treg Is Strain Specific and Correlates With Spontaneous Acceptance of Kidney Allografts.

Oh NA, O'Shea T, Ndishabandi DK, Yuan Q, Hong S, Gans J, Ge J, Gibney S, Chase C, Yang C, Rosales I, Shinoda K, Drew B, Kojima L, Russell PS, Madsen JC, Colvin RB, Alessandrini A.

Transplantation. 2020 Jan;104(1):39-53. doi: 10.1097/TP.0000000000002867.


A Peripheral Blood Gene Expression Signature to Diagnose Subclinical Acute Rejection.

Zhang W, Yi Z, Keung KL, Shang H, Wei C, Cravedi P, Sun Z, Xi C, Woytovich C, Farouk S, Huang W, Banu K, Gallon L, Magee CN, Najafian N, Samaniego M, Djamali A, Alexander SI, Rosales IA, Smith RN, Xiang J, Lerut E, Kuypers D, Naesens M, O'Connell PJ, Colvin R, Menon MC, Murphy B.

J Am Soc Nephrol. 2019 Aug;30(8):1481-1494. doi: 10.1681/ASN.2018111098. Epub 2019 Jul 5.


Pretransplant transcriptomic signature in peripheral blood predicts early acute rejection.

Zhang W, Yi Z, Wei C, Keung KL, Sun Z, Xi C, Woytovich C, Farouk S, Gallon L, Menon MC, Magee C, Najafian N, Samaniego MD, Djamali A, Alexander SI, Rosales IA, Smith RN, O'Connell PJ, Colvin R, Cravedi P, Murphy B.

JCI Insight. 2019 Jun 6;4(11). pii: 127543. doi: 10.1172/jci.insight.127543. eCollection 2019 Jun 6.


A First-in-Human Study To Assess the Safety and Pharmacokinetics of LYS228, a Novel Intravenous Monobactam Antibiotic in Healthy Volunteers.

Osborn M, Stachulski N, Sun H, Blais J, Venishetty V, Raccuglia M, Kankam M, Colvin R, Segal F.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e02592-18. doi: 10.1128/AAC.02592-18. Print 2019 Jul.


Safety and efficacy of eculizumab in the prevention of antibody-mediated rejection in living-donor kidney transplant recipients requiring desensitization therapy: A randomized trial.

Marks WH, Mamode N, Montgomery RA, Stegall MD, Ratner LE, Cornell LD, Rowshani AT, Colvin RB, Dain B, Boice JA, Glotz D; C10-001 Study Group.

Am J Transplant. 2019 Oct;19(10):2876-2888. doi: 10.1111/ajt.15364. Epub 2019 Apr 19.


IID572: A New Potentially Best-In-Class β-Lactamase Inhibitor.

Reck F, Bermingham A, Blais J, Casarez A, Colvin R, Dean CR, Furegati M, Gamboa L, Growcott E, Li C, Lopez S, Metzger L, Nocito S, Ossola F, Phizackerley K, Rasper D, Shaul J, Shen X, Simmons RL, Tang D, Tashiro K, Yue Q.

ACS Infect Dis. 2019 Jul 12;5(7):1045-1051. doi: 10.1021/acsinfecdis.9b00031. Epub 2019 Mar 27.


Pegunigalsidase alfa, a novel PEGylated enzyme replacement therapy for Fabry disease, provides sustained plasma concentrations and favorable pharmacodynamics: A 1-year Phase 1/2 clinical trial.

Schiffmann R, Goker-Alpan O, Holida M, Giraldo P, Barisoni L, Colvin RB, Jennette CJ, Maegawa G, Boyadjiev SA, Gonzalez D, Nicholls K, Tuffaha A, Atta MG, Rup B, Charney MR, Paz A, Szlaifer M, Alon S, Brill-Almon E, Chertkoff R, Hughes D.

J Inherit Metab Dis. 2019 May;42(3):534-544. doi: 10.1002/jimd.12080. Epub 2019 Apr 8.


Graft vasculopathy of vascularized composite allografts in humans: a literature review and retrospective study.

Ng ZY, Lellouch AG, Rosales IA, Geoghegan L, Gama AR, Colvin RB, Lantieri LA, Randolph MA, Cetrulo CL Jr.

Transpl Int. 2019 Aug;32(8):831-838. doi: 10.1111/tri.13421. Epub 2019 Apr 2. Review.


Efficacy of the pharmacologic chaperone migalastat in a subset of male patients with the classic phenotype of Fabry disease and migalastat-amenable variants: data from the phase 3 randomized, multicenter, double-blind clinical trial and extension study.

Germain DP, Nicholls K, Giugliani R, Bichet DG, Hughes DA, Barisoni LM, Colvin RB, Jennette JC, Skuban N, Castelli JP, Benjamin E, Barth JA, Viereck C.

Genet Med. 2019 Sep;21(9):1987-1997. doi: 10.1038/s41436-019-0451-z. Epub 2019 Feb 6.


Immunomics of Renal Allograft Acute T Cell-Mediated Rejection Biopsies of Tacrolimus- and Belatacept-Treated Patients.

van der Zwan M, Baan CC, Colvin RB, Smith RN, White RA, Ndishabandi D, Nigg AL, van den Bosch TPP, de Graav GN, Clahsen-van Groningen MC, Hesselink DA.

Transplant Direct. 2018 Dec 20;5(1):e418. doi: 10.1097/TXD.0000000000000857. eCollection 2019 Jan.


A first-in-human, randomized, double-blind, placebo-controlled, single and multiple ascending oral dose study to assess the safety, tolerability, and pharmacokinetics of BZF961 with and without ritonavir in healthy adult volunteers.

Youngberg S, Brandt E, Barve A, Machineni S, Jones CT, Dabovic K, Jones CL, Colvin RA.

J Drug Assess. 2018 Oct 24;7(1):66-74. doi: 10.1080/21556660.2018.1535438. eCollection 2018.


Mortality prediction in pediatric trauma.

Muisyo T, Bernardo EO, Camazine M, Colvin R, Thomas KA, Borgman MA, Spinella PC.

J Pediatr Surg. 2019 Aug;54(8):1613-1616. doi: 10.1016/j.jpedsurg.2018.08.045. Epub 2018 Sep 7.


The Safety and Antiviral Activity of BZF961 with or without Ritonavir in Patients Infected with Hepatitis C Virus: A Randomized, Multicenter Trial.

Lawitz E, Bidair M, Marbury T, Jones CT, Barve A, Magnusson B, Barkan DT, Bodendorf U, Bracken K, Canino E, Chen D, Dabovic K, Heimbach T, Ison M, Jones CL, Kovacs SJ, Lakshman JP, Li B, Raman P, Steiner-Swiat R, Thohan S, Wong KA, Zhong W, Colvin RA.

Clin Ther. 2018 Sep;40(9):1567-1581.e4. doi: 10.1016/j.clinthera.2018.07.019. Epub 2018 Sep 2.


Boundary spanning at the science-policy interface: the practitioners' perspectives.

Bednarek AT, Wyborn C, Cvitanovic C, Meyer R, Colvin RM, Addison PFE, Close SL, Curran K, Farooque M, Goldman E, Hart D, Mannix H, McGreavy B, Parris A, Posner S, Robinson C, Ryan M, Leith P.

Sustain Sci. 2018;13(4):1175-1183. doi: 10.1007/s11625-018-0550-9. Epub 2018 Mar 27.


Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae.

Dean CR, Barkan DT, Bermingham A, Blais J, Casey F, Casarez A, Colvin R, Fuller J, Jones AK, Li C, Lopez S, Metzger LE 4th, Mostafavi M, Prathapam R, Rasper D, Reck F, Ruzin A, Shaul J, Shen X, Simmons RL, Skewes-Cox P, Takeoka KT, Tamrakar P, Uehara T, Wei JR.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e01200-18. doi: 10.1128/AAC.01200-18. Print 2018 Oct.


Intravascular Large B-Cell Lymphoma Presenting with Diffuse Gallbladder Wall Thickening: A Case Report and Literature Review.

Al-Katib S, Colvin R, Sokhandon F.

Case Rep Radiol. 2018 Apr 22;2018:2494207. doi: 10.1155/2018/2494207. eCollection 2018.


Migalastat improves diarrhea in patients with Fabry disease: clinical-biomarker correlations from the phase 3 FACETS trial.

Schiffmann R, Bichet DG, Jovanovic A, Hughes DA, Giugliani R, Feldt-Rasmussen U, Shankar SP, Barisoni L, Colvin RB, Jennette JC, Holdbrook F, Mulberg A, Castelli JP, Skuban N, Barth JA, Nicholls K.

Orphanet J Rare Dis. 2018 Apr 27;13(1):68. doi: 10.1186/s13023-018-0813-7.


Large-scale environmental degradation results in inequitable impacts to already impoverished communities: A case study from the floating villages of Cambodia.

Althor G, Mahood S, Witt B, Colvin RM, Watson JEM.

Ambio. 2018 Nov;47(7):747-759. doi: 10.1007/s13280-018-1022-2. Epub 2018 Feb 19.


Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices.

Bajema IM, Wilhelmus S, Alpers CE, Bruijn JA, Colvin RB, Cook HT, D'Agati VD, Ferrario F, Haas M, Jennette JC, Joh K, Nast CC, Noël LH, Rijnink EC, Roberts ISD, Seshan SV, Sethi S, Fogo AB.

Kidney Int. 2018 Apr;93(4):789-796. doi: 10.1016/j.kint.2017.11.023. Epub 2018 Feb 16.


The effects of brain death and ischemia on tolerance induction are organ-specific.

Michel SG, Madariaga MLL, LaMuraglia GM 2nd, Villani V, Sekijima M, Farkash EA, Colvin RB, Sachs DH, Yamada K, Rosengard BR, Allan JS, Madsen JC.

Am J Transplant. 2018 May;18(5):1262-1269. doi: 10.1111/ajt.14674. Epub 2018 Mar 5.


Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.

Reck F, Bermingham A, Blais J, Capka V, Cariaga T, Casarez A, Colvin R, Dean CR, Fekete A, Gong W, Growcott E, Guo H, Jones AK, Li C, Li F, Lin X, Lindvall M, Lopez S, McKenney D, Metzger L, Moser HE, Prathapam R, Rasper D, Rudewicz P, Sethuraman V, Shen X, Shaul J, Simmons RL, Tashiro K, Tang D, Tjandra M, Turner N, Uehara T, Vitt C, Whitebread S, Yifru A, Zang X, Zhu Q.

Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755. doi: 10.1016/j.bmcl.2018.01.006. Epub 2018 Jan 4.


Long-term Nonhuman Primate Renal Allograft Survival Without Ongoing Immunosuppression in Recipients of Delayed Donor Bone Marrow Transplantation.

Hotta K, Oura T, Dehnadi A, Boskovic S, Matsunami M, Rosales I, Smith RN, Colvin RB, Cosimi AB, Kawai T.

Transplantation. 2018 Apr;102(4):e128-e136. doi: 10.1097/TP.0000000000002078.


RNA expression profiling of nonhuman primate renal allograft rejection identifies tolerance.

Smith RN, Matsunami M, Adam BA, Rosales IA, Oura T, Cosimi AB, Kawai T, Mengel M, Colvin RB.

Am J Transplant. 2018 Jun;18(6):1328-1339. doi: 10.1111/ajt.14637. Epub 2018 Feb 17.


RNA expression profiling of renal allografts in a nonhuman primate identifies variation in NK and endothelial gene expression.

Smith RN, Adam BA, Rosales IA, Matsunami M, Oura T, Cosimi AB, Kawai T, Mengel M, Colvin RB.

Am J Transplant. 2018 Jun;18(6):1340-1350. doi: 10.1111/ajt.14639. Epub 2018 Feb 2.


The Banff 2017 Kidney Meeting Report: Revised diagnostic criteria for chronic active T cell-mediated rejection, antibody-mediated rejection, and prospects for integrative endpoints for next-generation clinical trials.

Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, van Huyen JPD, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M.

Am J Transplant. 2018 Feb;18(2):293-307. doi: 10.1111/ajt.14625. Epub 2018 Jan 21.


Hepatitis B virus outreach to immigrant population in Greater Boston Area: Key to improving hepatitis B knowledge.

Djoufack R, Cheon SSY, Mohamed A, Faye F, Diouf K, Colvin R, Morrill J, Duffy-Keane AM, Perumalswami P, Jourdain G, Fusco D.

World J Gastroenterol. 2017 Nov 14;23(42):7626-7634. doi: 10.3748/wjg.v23.i42.7626.


Both platelets and fibrin deposition are increased in the glomeruli of mice after treatment with Shiga toxin-2.

Kushak RI, Ozaki M, Rosales IA, Boyle DC, Colvin RB, Ingelfinger JR, Stahl GL, Grabowski EF.

Kidney Int. 2017 Dec;92(6):1556-1557. doi: 10.1016/j.kint.2017.09.009. No abstract available.


LDL Receptor-Related Protein 2 (Megalin) as a Target Antigen in Human Kidney Anti-Brush Border Antibody Disease.

Larsen CP, Trivin-Avillach C, Coles P, Collins AB, Merchant M, Ma H, Wilkey DW, Ambruzs JM, Messias NC, Cossey LN, Rosales IA, Wooldridge T, Walker PD, Colvin RB, Klein J, Salant DJ, Beck LH Jr.

J Am Soc Nephrol. 2018 Feb;29(2):644-653. doi: 10.1681/ASN.2017060664. Epub 2017 Oct 26.


Lymphatic drainage system of the brain: A novel target for intervention of neurological diseases.

Sun BL, Wang LH, Yang T, Sun JY, Mao LL, Yang MF, Yuan H, Colvin RA, Yang XY.

Prog Neurobiol. 2018 Apr - May;163-164:118-143. doi: 10.1016/j.pneurobio.2017.08.007. Epub 2017 Sep 10. Review.


Perforated Meckel's Diverticulitis.

Colvin RW, Al-Katib S, Ebersole J.

J Gastrointest Surg. 2017 Dec;21(12):2126-2128. doi: 10.1007/s11605-017-3511-1. Epub 2017 Jul 25.


Penis Transplantation: First US Experience.

Cetrulo CL Jr, Li K, Salinas HM, Treiser MD, Schol I, Barrisford GW, McGovern FJ, Feldman AS, Grant MT, Tanrikut C, Lee JH, Ehrlichman RJ, Holzer PW, Choy GM, Liu RW, Ng ZY, Lellouch AG, Kurtz JM, Austen WG Jr, Winograd JM, Bojovic B, Eberlin KR, Rosales IA, Colvin RB, Ko DSC.

Ann Surg. 2018 May;267(5):983-988. doi: 10.1097/SLA.0000000000002241.


Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Costimulation Blockade.

Shah JA, Patel MS, Elias N, Navarro-Alvarez N, Rosales I, Wilkinson RA, Louras NJ, Hertl M, Fishman JA, Colvin RB, Cosimi AB, Markmann JF, Sachs DH, Vagefi PA.

Am J Transplant. 2017 Aug;17(8):2178-2185. doi: 10.1111/ajt.14341. Epub 2017 Jun 6.


Chronic Antibody-Mediated Rejection in Nonhuman Primate Renal Allografts: Validation of Human Histological and Molecular Phenotypes.

Adam BA, Smith RN, Rosales IA, Matsunami M, Afzali B, Oura T, Cosimi AB, Kawai T, Colvin RB, Mengel M.

Am J Transplant. 2017 Nov;17(11):2841-2850. doi: 10.1111/ajt.14327. Epub 2017 May 24.


A longitudinal analysis of data quality in a large pediatric data research network.

Khare R, Utidjian L, Ruth BJ, Kahn MG, Burrows E, Marsolo K, Patibandla N, Razzaghi H, Colvin R, Ranade D, Kitzmiller M, Eckrich D, Bailey LC.

J Am Med Inform Assoc. 2017 Nov 1;24(6):1072-1079. doi: 10.1093/jamia/ocx033.


Outcomes Related to the Use of Frozen Plasma or Pooled Solvent/Detergent-Treated Plasma in Critically Ill Children.

Camazine MN, Karam O, Colvin R, Leteurtre S, Demaret P, Tucci M, Muszynski JA, Stanworth S, Spinella PC; PlasmaTV Investigators.

Pediatr Crit Care Med. 2017 May;18(5):e215-e223. doi: 10.1097/PCC.0000000000001149.


A proposal for standardized grading of chronic changes in native kidney biopsy specimens.

Sethi S, D'Agati VD, Nast CC, Fogo AB, De Vriese AS, Markowitz GS, Glassock RJ, Fervenza FC, Seshan SV, Rule A, Racusen LC, Radhakrishnan J, Winearls CG, Appel GB, Bajema IM, Chang A, Colvin RB, Cook HT, Hariharan S, Herrera Hernandez LP, Kambham N, Mengel M, Nath KA, Rennke HG, Ronco P, Rovin BH, Haas M.

Kidney Int. 2017 Apr;91(4):787-789. doi: 10.1016/j.kint.2017.01.002.


Erythropoietin Receptor-Mediated Molecular Crosstalk Promotes T Cell Immunoregulation and Transplant Survival.

Purroy C, Fairchild RL, Tanaka T, Baldwin WM 3rd, Manrique J, Madsen JC, Colvin RB, Alessandrini A, Blazar BR, Fribourg M, Donadei C, Maggiore U, Heeger PS, Cravedi P.

J Am Soc Nephrol. 2017 Aug;28(8):2377-2392. doi: 10.1681/ASN.2016101100. Epub 2017 Mar 16.


Association of Fetal Heart Rate Baseline Change and Neonatal Outcomes.

Yang M, Stout MJ, López JD, Colvin R, Macones GA, Cahill AG.

Am J Perinatol. 2017 Jul;34(9):879-886. doi: 10.1055/s-0037-1600911. Epub 2017 Mar 16.


Origin of Enriched Regulatory T Cells in Patients Receiving Combined Kidney-Bone Marrow Transplantation to Induce Transplantation Tolerance.

Sprangers B, DeWolf S, Savage TM, Morokata T, Obradovic A, LoCascio SA, Shonts B, Zuber J, Lau SP, Shah R, Morris H, Steshenko V, Zorn E, Preffer FI, Olek S, Dombkowski DM, Turka LA, Colvin R, Winchester R, Kawai T, Sykes M.

Am J Transplant. 2017 Aug;17(8):2020-2032. doi: 10.1111/ajt.14251. Epub 2017 Apr 10.


Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy.

Sise ME, Wisocky J, Rosales IA, Chute D, Holmes JA, Corapi KM, Babitt JL, Tangren JS, Hashemi N, Lundquist AL, Williams WW, Mount DB, Andersson KL, Rennke HG, Smith RN, Colvin R, Thadhani RI, Chung RT.

Kidney Int Rep. 2016 Sep;1(3):135-143.


The Banff 2015 Kidney Meeting Report: Current Challenges in Rejection Classification and Prospects for Adopting Molecular Pathology.

Loupy A, Haas M, Solez K, Racusen L, Glotz D, Seron D, Nankivell BJ, Colvin RB, Afrouzian M, Akalin E, Alachkar N, Bagnasco S, Becker JU, Cornell L, Drachenberg C, Dragun D, de Kort H, Gibson IW, Kraus ES, Lefaucheur C, Legendre C, Liapis H, Muthukumar T, Nickeleit V, Orandi B, Park W, Rabant M, Randhawa P, Reed EF, Roufosse C, Seshan SV, Sis B, Singh HK, Schinstock C, Tambur A, Zeevi A, Mengel M.

Am J Transplant. 2017 Jan;17(1):28-41. doi: 10.1111/ajt.14107.


A Diacylglycerol Transferase 1 Inhibitor Is a Potent Hepatitis C Antiviral in Vitro but Not in Patients in a Randomized Clinical Trial.

Gane E, Stedman C, Dole K, Chen J, Meyers CD, Wiedmann B, Zhang J, Raman P, Colvin RA.

ACS Infect Dis. 2017 Feb 10;3(2):144-151. doi: 10.1021/acsinfecdis.6b00138. Epub 2016 Nov 8.


Trabeculectomy Combined With Collagen Matrix Implant (Ologen).

Perez CI, Mellado F, Jones A, Colvin R.

J Glaucoma. 2017 Jan;26(1):54-58. doi: 10.1097/IJG.0000000000000551.


Haptoglobin or Hemopexin Therapy Prevents Acute Adverse Effects of Resuscitation After Prolonged Storage of Red Cells.

Graw JA, Mayeur C, Rosales I, Liu Y, Sabbisetti VS, Riley FE, Rechester O, Malhotra R, Warren HS, Colvin RB, Bonventre JV, Bloch DB, Zapol WM.

Circulation. 2016 Sep 27;134(13):945-60. doi: 10.1161/CIRCULATIONAHA.115.019955. Epub 2016 Aug 11.

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