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Items: 1 to 50 of 317

1.

Multivariate MR biomarkers better predict cognitive dysfunction in mouse models of Alzheimer's disease.

Badea A, Delpratt NA, Anderson RJ, Dibb R, Qi Y, Wei H, Liu C, Wetsel WC, Avants BB, Colton C.

Magn Reson Imaging. 2019 Jul;60:52-67. doi: 10.1016/j.mri.2019.03.022. Epub 2019 Mar 30.

PMID:
30940494
2.

Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply.

Evron Y, Colton CK, Ludwig B, Weir GC, Zimermann B, Maimon S, Neufeld T, Shalev N, Goldman T, Leon A, Yavriyants K, Shabtay N, Rozenshtein T, Azarov D, DiIenno AR, Steffen A, de Vos P, Bornstein SR, Barkai U, Rotem A.

Sci Rep. 2018 Apr 25;8(1):6508. doi: 10.1038/s41598-018-23862-w.

3.

Two Aviation Accident Investigation Questionnaires for Passenger and Crew Survival Factors and Injuries.

Davies JM, Wallace WA, Colton CL, Yoo KI, Maurino M.

Aerosp Med Hum Perform. 2018 May 1;89(5):483-486. doi: 10.3357/AMHP.5030.2018.

PMID:
29673436
4.

T3 Induces Both Markers of Maturation and Aging in Pancreatic β-Cells.

Aguayo-Mazzucato C, Lee TB Jr, Matzko M, DiIenno A, Rezanejad H, Ramadoss P, Scanlan T, Zavacki AM, Larsen PR, Hollenberg A, Colton C, Sharma A, Bonner-Weir S.

Diabetes. 2018 Jul;67(7):1322-1331. doi: 10.2337/db18-0030. Epub 2018 Apr 6.

5.

Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes.

Ludwig B, Ludwig S, Steffen A, Knauf Y, Zimerman B, Heinke S, Lehmann S, Schubert U, Schmid J, Bleyer M, Schönmann U, Colton CK, Bonifacio E, Solimena M, Reichel A, Schally AV, Rotem A, Barkai U, Grinberg-Rashi H, Kaup FJ, Avni Y, Jones P, Bornstein SR.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11745-11750. doi: 10.1073/pnas.1708420114. Epub 2017 Oct 16.

6.

Speaking out about gender imbalance in invited speakers improves diversity.

Klein RS, Voskuhl R, Segal BM, Dittel BN, Lane TE, Bethea JR, Carson MJ, Colton C, Rosi S, Anderson A, Piccio L, Goverman JM, Benveniste EN, Brown MA, Tiwari-Woodruff SK, Harris TH, Cross AH.

Nat Immunol. 2017 Apr 18;18(5):475-478. doi: 10.1038/ni.3707. No abstract available.

7.

The fornix provides multiple biomarkers to characterize circuit disruption in a mouse model of Alzheimer's disease.

Badea A, Kane L, Anderson RJ, Qi Y, Foster M, Cofer GP, Medvitz N, Buckley AF, Badea AK, Wetsel WC, Colton CA.

Neuroimage. 2016 Nov 15;142:498-511. doi: 10.1016/j.neuroimage.2016.08.014. Epub 2016 Aug 10.

8.

The effects of the apoE4 genotype on the developing mouse retina.

Maharshak I, Salomon-Zimri S, Antes R, Liraz O, Nisgav Y, Livnat T, Weinberger D, Colton CA, Solomon AS, Michaelson DM.

Exp Eye Res. 2016 Apr;145:17-25. doi: 10.1016/j.exer.2015.11.001. Epub 2015 Nov 7.

PMID:
26554939
9.

Chronic Systemic Immune Dysfunction in African-Americans with Small Vessel-Type Ischemic Stroke.

Brown CM, Bushnell CD, Samsa GP, Goldstein LB, Colton CA.

Transl Stroke Res. 2015 Dec;6(6):430-6. doi: 10.1007/s12975-015-0424-8. Epub 2015 Sep 15.

10.

Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation.

Papas KK, Bellin MD, Sutherland DE, Suszynski TM, Kitzmann JP, Avgoustiniatos ES, Gruessner AC, Mueller KR, Beilman GJ, Balamurugan AN, Loganathan G, Colton CK, Koulmanda M, Weir GC, Wilhelm JJ, Qian D, Niland JC, Hering BJ.

PLoS One. 2015 Aug 10;10(8):e0134428. doi: 10.1371/journal.pone.0134428. eCollection 2015.

11.

MAFA and T3 Drive Maturation of Both Fetal Human Islets and Insulin-Producing Cells Differentiated From hESC.

Aguayo-Mazzucato C, DiIenno A, Hollister-Lock J, Cahill C, Sharma A, Weir G, Colton C, Bonner-Weir S.

J Clin Endocrinol Metab. 2015 Oct;100(10):3651-9. doi: 10.1210/jc.2015-2632. Epub 2015 Jul 24.

12.
13.

Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease.

Kan MJ, Lee JE, Wilson JG, Everhart AL, Brown CM, Hoofnagle AN, Jansen M, Vitek MP, Gunn MD, Colton CA.

J Neurosci. 2015 Apr 15;35(15):5969-82. doi: 10.1523/JNEUROSCI.4668-14.2015.

14.

The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment.

Hoos MD, Vitek MP, Ridnour LA, Wilson J, Jansen M, Everhart A, Wink DA, Colton CA.

Mol Neurodegener. 2014 Nov 17;9:50. doi: 10.1186/1750-1326-9-50.

15.

Oxygen supply by photosynthesis to an implantable islet cell device.

Evron Y, Zimermann B, Ludwig B, Barkai U, Colton CK, Weir GC, Arieli B, Maimon S, Shalev N, Yavriyants K, Goldman T, Gendler Z, Eizen L, Vardi P, Bloch K, Barthel A, Bornstein SR, Rotem A.

Horm Metab Res. 2015 Jan;47(1):24-30. doi: 10.1055/s-0034-1394375. Epub 2014 Nov 3.

PMID:
25365509
16.
17.

mNos2 deletion and human NOS2 replacement in Alzheimer disease models.

Colton CA, Wilson JG, Everhart A, Wilcock DM, Puoliväli J, Heikkinen T, Oksman J, Jääskeläinen O, Lehtimäki K, Laitinen T, Vartiainen N, Vitek MP.

J Neuropathol Exp Neurol. 2014 Aug;73(8):752-69. doi: 10.1097/NEN.0000000000000094.

18.
19.

Oxygen supply to encapsulated therapeutic cells.

Colton CK.

Adv Drug Deliv Rev. 2014 Apr;67-68:93-110. doi: 10.1016/j.addr.2014.02.007. Epub 2014 Feb 27. Review.

PMID:
24582600
20.

Transplantation of human islets without immunosuppression.

Ludwig B, Reichel A, Steffen A, Zimerman B, Schally AV, Block NL, Colton CK, Ludwig S, Kersting S, Bonifacio E, Solimena M, Gendler Z, Rotem A, Barkai U, Bornstein SR.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19054-8. doi: 10.1073/pnas.1317561110. Epub 2013 Oct 28.

21.

Longitudinal study of differential protein expression in an Alzheimer's mouse model lacking inducible nitric oxide synthase.

Hoos MD, Richardson BM, Foster MW, Everhart A, Thompson JW, Moseley MA, Colton CA.

J Proteome Res. 2013 Oct 4;12(10):4462-77. doi: 10.1021/pr4005103. Epub 2013 Sep 18.

22.

The efficacy of an immunoisolating membrane system for islet xenotransplantation in minipigs.

Neufeld T, Ludwig B, Barkai U, Weir GC, Colton CK, Evron Y, Balyura M, Yavriyants K, Zimermann B, Azarov D, Maimon S, Shabtay N, Rozenshtein T, Lorber D, Steffen A, Willenz U, Bloch K, Vardi P, Taube R, de Vos P, Lewis EC, Bornstein SR, Rotem A.

PLoS One. 2013 Aug 1;8(8):e70150. doi: 10.1371/journal.pone.0070150. Print 2013.

23.

Elevated copper in the amyloid plaques and iron in the cortex are observed in mouse models of Alzheimer's disease that exhibit neurodegeneration.

Bourassa MW, Leskovjan AC, Tappero RV, Farquhar ER, Colton CA, Van Nostrand WE, Miller LM.

Biomed Spectrosc Imaging. 2013 Apr 1;2(2):129-139.

24.

Respirators and surgical masks-exploring the differences.

Colton CE, Townsend MC.

Workplace Health Saf. 2013 Mar;61(3):99-101. doi: 10.3928/21650799-20130226-03.

PMID:
23452129
25.

Microglial-neuronal interactions during neurodegenerative diseases.

Colton CA.

J Neuroimmune Pharmacol. 2013 Mar;8(1):4-6. doi: 10.1007/s11481-013-9437-9. Epub 2013 Feb 13.

26.

Immune heterogeneity in neuroinflammation: dendritic cells in the brain.

Colton CA.

J Neuroimmune Pharmacol. 2013 Mar;8(1):145-62. doi: 10.1007/s11481-012-9414-8. Epub 2012 Nov 1. Review.

27.

Enhanced oxygen supply improves islet viability in a new bioartificial pancreas.

Barkai U, Weir GC, Colton CK, Ludwig B, Bornstein SR, Brendel MD, Neufeld T, Bremer C, Leon A, Evron Y, Yavriyants K, Azarov D, Zimermann B, Maimon S, Shabtay N, Balyura M, Rozenshtein T, Vardi P, Bloch K, de Vos P, Rotem A.

Cell Transplant. 2013;22(8):1463-76. doi: 10.3727/096368912X657341. Epub 2012 Oct 3.

PMID:
23043896
28.

Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1.

Ridnour LA, Dhanapal S, Hoos M, Wilson J, Lee J, Cheng RY, Brueggemann EE, Hines HB, Wilcock DM, Vitek MP, Wink DA, Colton CA.

J Neurochem. 2012 Dec;123(5):736-49. doi: 10.1111/jnc.12028. Epub 2012 Oct 25.

29.

Real-time fit of a respirator during simulated health care tasks.

Hauge J, Roe M, Brosseau LM, Colton C.

J Occup Environ Hyg. 2012;9(10):563-71. doi: 10.1080/15459624.2012.711699.

PMID:
22924959
30.

Human apolipoprotein E2 promotes parenchymal amyloid deposition and neuronal loss in vasculotropic mutant amyloid-β protein Tg-SwDI mice.

Xu F, Vitek MP, Colton CA, Previti ML, Davis J, Van Nostrand WE.

J Alzheimers Dis. 2012;31(2):359-69. doi: 10.3233/JAD-2012-120421.

PMID:
22635103
31.

Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist.

Ludwig B, Rotem A, Schmid J, Weir GC, Colton CK, Brendel MD, Neufeld T, Block NL, Yavriyants K, Steffen A, Ludwig S, Chavakis T, Reichel A, Azarov D, Zimermann B, Maimon S, Balyura M, Rozenshtein T, Shabtay N, Vardi P, Bloch K, de Vos P, Schally AV, Bornstein SR, Barkai U.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5022-7. doi: 10.1073/pnas.1201868109. Epub 2012 Mar 5.

32.

Lithium treatment of APPSwDI/NOS2-/- mice leads to reduced hyperphosphorylated tau, increased amyloid deposition and altered inflammatory phenotype.

Sudduth TL, Wilson JG, Everhart A, Colton CA, Wilcock DM.

PLoS One. 2012;7(2):e31993. doi: 10.1371/journal.pone.0031993. Epub 2012 Feb 9.

33.

APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics.

Vitek MP, Christensen DJ, Wilcock D, Davis J, Van Nostrand WE, Li FQ, Colton CA.

Neurodegener Dis. 2012;10(1-4):122-6. doi: 10.1159/000334914. Epub 2012 Feb 9.

34.

Heteromeric heat-sensitive transient receptor potential channels exhibit distinct temperature and chemical response.

Cheng W, Yang F, Liu S, Colton CK, Wang C, Cui Y, Cao X, Zhu MX, Sun C, Wang K, Zheng J.

J Biol Chem. 2012 Mar 2;287(10):7279-88. doi: 10.1074/jbc.M111.305045. Epub 2011 Dec 19.

35.

Diverse inflammatory responses in transgenic mouse models of Alzheimer's disease and the effect of immunotherapy on these responses.

Wilcock DM, Zhao Q, Morgan D, Gordon MN, Everhart A, Wilson JG, Lee JE, Colton CA.

ASN Neuro. 2011 Nov 30;3(5):249-58. doi: 10.1042/AN20110018.

36.

Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies.

Shineman DW, Basi GS, Bizon JL, Colton CA, Greenberg BD, Hollister BA, Lincecum J, Leblanc GG, Lee LB, Luo F, Morgan D, Morse I, Refolo LM, Riddell DR, Scearce-Levie K, Sweeney P, Yrjänheikki J, Fillit HM.

Alzheimers Res Ther. 2011 Sep 28;3(5):28. doi: 10.1186/alzrt90.

37.

Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence.

Wilcock DM, Morgan D, Gordon MN, Taylor TL, Ridnour LA, Wink DA, Colton CA.

J Neuroinflammation. 2011 Sep 9;8:115. doi: 10.1186/1742-2094-8-115.

38.

Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators.

Xing X, Chang LC, Kong Q, Colton CK, Lai L, Glicksman MA, Lin CL, Cuny GD.

Bioorg Med Chem Lett. 2011 Oct 1;21(19):5774-7. doi: 10.1016/j.bmcl.2011.08.009. Epub 2011 Aug 8.

39.

Apolipoprotein E and peptide mimetics modulate inflammation by binding the SET protein and activating protein phosphatase 2A.

Christensen DJ, Ohkubo N, Oddo J, Van Kanegan MJ, Neil J, Li F, Colton CA, Vitek MP.

J Immunol. 2011 Feb 15;186(4):2535-42. doi: 10.4049/jimmunol.1002847.

40.

Nitric oxide and redox mechanisms in the immune response.

Wink DA, Hines HB, Cheng RY, Switzer CH, Flores-Santana W, Vitek MP, Ridnour LA, Colton CA.

J Leukoc Biol. 2011 Jun;89(6):873-91. doi: 10.1189/jlb.1010550. Epub 2011 Jan 13. Review.

41.

Quantitative assessment of islets of Langerhans encapsulated in alginate.

Johnson AS, O'Sullivan E, D'Aoust LN, Omer A, Bonner-Weir S, Fisher RJ, Weir GC, Colton CK.

Tissue Eng Part C Methods. 2011 Apr;17(4):435-49. doi: 10.1089/ten.TEC.2009.0510. Epub 2011 Jan 16.

42.

Enhanced capillary amyloid angiopathy-associated pathology in Tg-SwDI mice with deleted nitric oxide synthase 2.

Van Nostrand WE, Xu F, Rozemuller AJ, Colton CA.

Stroke. 2010 Oct;41(10 Suppl):S135-8. doi: 10.1161/STROKEAHA.110.595272.

43.

Quantitative analysis of cell composition and purity of human pancreatic islet preparations.

Pisania A, Weir GC, O'Neil JJ, Omer A, Tchipashvili V, Lei J, Colton CK, Bonner-Weir S.

Lab Invest. 2010 Nov;90(11):1661-75. doi: 10.1038/labinvest.2010.124. Epub 2010 Aug 9.

44.

Enumeration of islets by nuclei counting and light microscopic analysis.

Pisania A, Papas KK, Powers DE, Rappel MJ, Omer A, Bonner-Weir S, Weir GC, Colton CK.

Lab Invest. 2010 Nov;90(11):1676-86. doi: 10.1038/labinvest.2010.125. Epub 2010 Aug 9.

45.

Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity.

Colton CK, Kong Q, Lai L, Zhu MX, Seyb KI, Cuny GD, Xian J, Glicksman MA, Lin CL.

J Biomol Screen. 2010 Jul;15(6):653-62. doi: 10.1177/1087057110370998. Epub 2010 May 27.

46.

An apolipoprotein E-mimetic stimulates axonal regeneration and remyelination after peripheral nerve injury.

Li FQ, Fowler KA, Neil JE, Colton CA, Vitek MP.

J Pharmacol Exp Ther. 2010 Jul;334(1):106-15. doi: 10.1124/jpet.110.167882. Epub 2010 Apr 20.

47.

Prediction of marginal mass required for successful islet transplantation.

Papas KK, Colton CK, Qipo A, Wu H, Nelson RA, Hering BJ, Weir GC, Koulmanda M.

J Invest Surg. 2010 Feb;23(1):28-34. doi: 10.3109/08941930903410825.

48.

Assessing activation states in microglia.

Colton C, Wilcock DM.

CNS Neurol Disord Drug Targets. 2010 Apr;9(2):174-91. Review.

PMID:
20205642
49.

Rat islet cell aggregates are superior to islets for transplantation in microcapsules.

O'Sullivan ES, Johnson AS, Omer A, Hollister-Lock J, Bonner-Weir S, Colton CK, Weir GC.

Diabetologia. 2010 May;53(5):937-945. doi: 10.1007/s00125-009-1653-8. Epub 2010 Jan 26.

50.

Accurate control of oxygen level in cells during culture on silicone rubber membranes with application to stem cell differentiation.

Powers DE, Millman JR, Bonner-Weir S, Rappel MJ, Colton CK.

Biotechnol Prog. 2010 May-Jun;26(3):805-18. doi: 10.1002/btpr.359.

PMID:
20039374

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