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Items: 1 to 50 of 189

1.

The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418.

Ferguson MW, Gerak CAN, Chow CCT, Rastelli EJ, Elmore KE, Stahl F, Hosseini-Farahabadi S, Baradaran-Heravi A, Coltart DM, Roberge M.

PLoS One. 2019 May 23;14(5):e0216423. doi: 10.1371/journal.pone.0216423. eCollection 2019.

2.

Formation, Alkylation, and Hydrolysis of Chiral Nonracemic N-Amino Cyclic Carbamate Hydrazones: An Approach to the Enantioselective α-Alkylation of Ketones.

Huynh U, McDonald SL, Lim D, Uddin MN, Wengryniuk SE, Dey S, Coltart DM.

J Org Chem. 2018 Nov 2;83(21):12951-12964. doi: 10.1021/acs.joc.8b00655. Epub 2018 Oct 3.

PMID:
30200759
3.

A Mismatch-Free Strategy for the Diastereoselective α,α-Bisalkylation of Chiral Nonracemic Methyl Ketones.

Uddin MN, Tarsis EM, Wu CH, Wu JI, Coltart DM.

Org Lett. 2018 Jul 6;20(13):3723-3727. doi: 10.1021/acs.orglett.8b01146. Epub 2018 Jun 13.

PMID:
29897766
4.

Asymmetric Induction in Hydroacylation by Cooperative Iminium Ion-Transition-Metal Catalysis.

Rastelli EJ, Truong NT, Coltart DM.

Org Lett. 2016 Nov 4;18(21):5588-5591. Epub 2016 Oct 21.

PMID:
27767317
5.

Asymmetric Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride.

Rastelli EJ, Coltart DM.

J Org Chem. 2016 Oct 21;81(20):9567-9575. Epub 2016 Oct 6.

PMID:
27657347
6.

Direct carbon-carbon bond formation via reductive soft enolization: a syn-selective Mannich addition of α-iodo thioesters.

Truong N, Sauer SJ, Seraphin-Hatcher C, Coltart DM.

Org Biomol Chem. 2016 Aug 16;14(33):7864-8. doi: 10.1039/c6ob01244b.

PMID:
27492274
7.

Diastereoselective addition of Grignard reagents to α-epoxy N-sulfonyl hydrazones.

Uteuliyev MM, Nguyen TT, Coltart DM.

Nat Chem. 2015 Dec;7(12):1024-7. doi: 10.1038/nchem.2364. Epub 2015 Oct 19.

PMID:
26587719
8.

A Concise and Highly Enantioselective Total Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride: Definitive Absolute Stereochemical Assignment of the Mefloquines.

Rastelli EJ, Coltart DM.

Angew Chem Int Ed Engl. 2015 Nov 16;54(47):14070-4. doi: 10.1002/anie.201507304. Epub 2015 Sep 30.

PMID:
26422780
9.

Asymmetric anti-aldol addition of achiral ketones via chiral N-amino cyclic carbamate hydrazones.

Knight JD, Coltart DM.

Chem Commun (Camb). 2013 Sep 4;49(68):7495-7. doi: 10.1039/c3cc44716b.

PMID:
23873079
10.

Asymmetric total synthesis of apratoxin D.

Robertson BD, Wengryniuk SE, Coltart DM.

Org Lett. 2012 Oct 19;14(20):5192-5. doi: 10.1021/ol302309c. Epub 2012 Oct 11.

PMID:
23057680
11.

Catalytic asymmetric addition of thiols to nitrosoalkenes leading to chiral non-racemic α-sulfenyl ketones.

Hatcher JM, Kohler MC, Coltart DM.

Org Lett. 2011 Aug 5;13(15):3810-3. doi: 10.1021/ol2012633. Epub 2011 Jun 29.

PMID:
21714489
12.

Asymmetric total synthesis of the antimalarial drug (+)-mefloquine hydrochloride via chiral N-amino cyclic carbamate hydrazones.

Knight JD, Sauer SJ, Coltart DM.

Org Lett. 2011 Jun 17;13(12):3118-21. doi: 10.1021/ol2010193. Epub 2011 May 26.

PMID:
21615091
13.

Regioselective asymmetric α,α-bisalkylation of ketones via complex-induced syn-deprotonation of chiral N-amino cyclic carbamate hydrazones.

Wengryniuk SE, Lim D, Coltart DM.

J Am Chem Soc. 2011 Jun 8;133(22):8714-20. doi: 10.1021/ja202267k. Epub 2011 May 12.

PMID:
21510644
14.

Asymmetric total synthesis of (+)- and (-)-clusianone and (+)- and (-)-clusianone methyl enol ether via ACC alkylation and evaluation of their anti-HIV activity.

Garnsey MR, Matous JA, Kwiek JJ, Coltart DM.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2406-9. doi: 10.1016/j.bmcl.2011.02.074. Epub 2011 Feb 23.

15.

CyberKnife radiosurgery for an intracardiac metastasis.

Martin AG, Coltart DJ, Plowman PN.

BMJ Case Rep. 2011 Mar 3;2011. pii: bcr0720103197. doi: 10.1136/bcr.07.2010.3197. No abstract available.

16.

Origins of stereoselectivity in the α-alkylation of chiral hydrazones.

Krenske EH, Houk KN, Lim D, Wengryniuk SE, Coltart DM.

J Org Chem. 2010 Dec 17;75(24):8578-84. doi: 10.1021/jo1019877. Epub 2010 Nov 11.

17.
18.

Direct carbon-carbon bond formation via soft enolization: aldol addition of α-halogenated thioesters.

Yost JM, Alfie RJ, Tarsis EM, Chong I, Coltart DM.

Chem Commun (Camb). 2011 Jan 7;47(1):571-2. doi: 10.1039/c0cc02345k. Epub 2010 Oct 21.

PMID:
20963247
19.
20.

Direct carbon-carbon bond formation via soft enolization: a biomimetic asymmetric Mannich reaction of phenylacetate thioesters.

Kohler MC, Yost JM, Garnsey MR, Coltart DM.

Org Lett. 2010 Aug 6;12(15):3376-9. doi: 10.1021/ol101152b.

PMID:
20608684
22.

Overcoming the limitations of the Morita-Baylis-Hillman reaction: a rapid and general synthesis of alpha-alkenyl-beta'-hydroxy thioesters.

Tarsis E, Gromova A, Lim D, Zhou G, Coltart DM.

Org Lett. 2008 Nov 6;10(21):4819-22. doi: 10.1021/ol801896q. Epub 2008 Oct 10.

PMID:
18844367
23.
24.

Simple and efficient asymmetric alpha-alkylation and alpha,alpha-bisalkylation of acyclic ketones by using chiral N-amino cyclic carbamate hydrazones.

Lim D, Coltart DM.

Angew Chem Int Ed Engl. 2008;47(28):5207-10. doi: 10.1002/anie.200800848. No abstract available.

PMID:
18528835
25.

A facile and efficient anti-selective four-component direct aldol addition via chemoselective thioester enolate formation.

Zhou G, Yost JM, Sauer SJ, Coltart DM.

Org Lett. 2007 Oct 25;9(22):4663-5. Epub 2007 Sep 29.

PMID:
17902688
26.

Direct carbon-carbon bond formation via soft enolization: a facile and efficient synthesis of 1,3-diketones.

Lim D, Fang F, Zhou G, Coltart DM.

Org Lett. 2007 Oct 11;9(21):4139-42. Epub 2007 Sep 18.

PMID:
17877360
27.

A facile and efficient direct aldol addition of simple thioesters.

Yost JM, Zhou G, Coltart DM.

Org Lett. 2006 Mar 30;8(7):1503-6.

PMID:
16562927
28.

Derivatized amino acids relevant to native peptide synthesis by chemical ligation and acyl transfer.

Clive DL, Hisaindee S, Coltart DM.

J Org Chem. 2003 Nov 28;68(24):9247-54.

PMID:
14629143
29.

Novel synthetic approach to the 8,10-dimethyl anti-syn-anti-perhydrophenanthrene skeleton.

Coltart DM, Danishefsky SJ.

Org Lett. 2003 Apr 17;5(8):1289-92.

PMID:
12688741
30.

On the power of chemical synthesis: immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines.

Ragupathi G, Coltart DM, Williams LJ, Koide F, Kagan E, Allen J, Harris C, Glunz PW, Livingston PO, Danishefsky SJ.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13699-704. Epub 2002 Oct 1.

31.

Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains.

Coltart DM, Royyuru AK, Williams LJ, Glunz PW, Sames D, Kuduk SD, Schwarz JB, Chen XT, Danishefsky SJ, Live DH.

J Am Chem Soc. 2002 Aug 21;124(33):9833-44.

PMID:
12175243
32.

Constructing an adenocarcinoma vaccine: immunization of mice with synthetic KH-1 nonasaccharide stimulates anti-KH-1 and anti-Le(y) antibodies.

Ragupathi G, Deshpande PP, Coltart DM, Kim HM, Williams LJ, Danishefsky SJ, Livingston PO.

Int J Cancer. 2002 May 10;99(2):207-12.

33.
34.

Balloon pulmonary valvuloplasty in carcinoid syndrome.

Obel O, Coltart DJ, Signy M.

Heart. 2000 Dec;84(6):E13.

35.

Gender differences in sensitivity to adrenergic agonists of forearm resistance vasculature.

Kneale BJ, Chowienczyk PJ, Brett SE, Coltart DJ, Ritter JM.

J Am Coll Cardiol. 2000 Oct;36(4):1233-8.

36.

Bedside cardiology

Coltart DJ.

Postgrad Med J. 2000 Aug;76(898):525. No abstract available.

37.

Cardiovascular therapeutics

Coltart DJ.

Postgrad Med J. 2000 Jun;76(896):381D. No abstract available.

38.

A case of digoxin toxicity.

Singh-Ranger D, Coltart DJ.

Br J Hosp Med. 1997 Oct 1-14;58(7):319-20. No abstract available.

PMID:
9509051
39.

Vasoconstrictor sensitivity to noradrenaline and NG-monomethyl-L-arginine in men and women.

Kneale BJ, Chowienczyk PJ, Cockcroft JR, Coltart DJ, Ritter JM.

Clin Sci (Lond). 1997 Dec;93(6):513-8.

PMID:
9497787
40.

Asymptomatic murmurs.

Biggart SA, Coltart DJ.

Postgrad Med J. 1997 Sep;73(863):597-8. No abstract available.

41.
42.

Coronary subclavian steal syndrome following coronary by-pass surgery.

Kneale BJ, Irvine AT, Coltart DJ.

Postgrad Med J. 1996 Jun;72(848):358-60.

43.

Coronary artery stents.

Stewart AJ, Coltart DJ.

Postgrad Med J. 1996 May;72(847):274-6. Review.

44.

Relationships between nutrient intake and progression/regression of coronary atherosclerosis as assessed by serial quantitative angiography.

Watts GF, Lewis B, Jackson P, Burke V, Lewis ES, Brunt JN, Coltart DJ.

Can J Cardiol. 1995 Oct;11 Suppl G:110G-114G.

PMID:
7585283
45.

Quantitative coronary cineangiography for the study of atherosclerosis.

Brunt JN, Watts GF, Lewis B, Smith LD, Coltart DJ.

Med Eng Phys. 1995 Jul;17(5):356-65.

PMID:
7670695
47.

Angiotensin converting enzyme gene polymorphism and the course of angiographically defined coronary artery disease.

Talmud PJ, Watts GF, McBride S, Mandalia S, Brunt JN, Coltart DJ, Lewis B, Humphries SE.

Atherosclerosis. 1995 Apr 7;114(1):133-5. No abstract available.

PMID:
7605372
48.

Metabolic determinants of the course of coronary artery disease in men.

Watts GF, Mandalia S, Slavin BM, Brunt JN, Coltart DJ, Lewis B.

Clin Chem. 1994 Dec;40(12):2240-6.

49.

Diltiazem hydrochloride.

Harrington D, Coltart DJ.

Br J Hosp Med. 1994 Oct 19-Nov 1;52(8):413-5.

PMID:
7858832
50.

Recent advances in cardiology.

Lawson CS, Coltart DJ.

Postgrad Med J. 1994 Apr;70(822):257-74. Review. No abstract available.

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