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Items: 31

1.

Glutamate Dehydrogenase to the Rescue.

Coloff JL.

Mol Cell. 2018 Jan 4;69(1):1-2. doi: 10.1016/j.molcel.2017.12.015.

PMID:
29304329
2.

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells.

Hung YP, Teragawa C, Kosaisawe N, Gillies TE, Pargett M, Minguet M, Distor K, Rocha-Gregg BL, Coloff JL, Keibler MA, Stephanopoulos G, Yellen G, Brugge JS, Albeck JG.

Elife. 2017 Dec 14;6. pii: e27293. doi: 10.7554/eLife.27293.

3.

Identification of cancer genes that are independent of dominant proliferation and lineage programs.

Selfors LM, Stover DG, Harris IS, Brugge JS, Coloff JL.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11276-E11284. doi: 10.1073/pnas.1714877115. Epub 2017 Dec 11.

4.

Metabolic changes promote rejection of oncogenic cells.

Coloff JL, Brugge JS.

Nat Cell Biol. 2017 Apr 27;19(5):414-415. doi: 10.1038/ncb3521.

PMID:
28446818
5.

Starved epithelial cells uptake extracellular matrix for survival.

Muranen T, Iwanicki MP, Curry NL, Hwang J, DuBois CD, Coloff JL, Hitchcock DS, Clish CB, Brugge JS, Kalaany NY.

Nat Commun. 2017 Jan 10;8:13989. doi: 10.1038/ncomms13989.

6.

ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.

Muranen T, Selfors LM, Hwang J, Gallegos LL, Coloff JL, Thoreen CC, Kang SA, Sabatini DM, Mills GB, Brugge JS.

Cancer Res. 2016 Dec 15;76(24):7168-7180. Epub 2016 Oct 20.

7.

The Role of Proliferation in Determining Response to Neoadjuvant Chemotherapy in Breast Cancer: A Gene Expression-Based Meta-Analysis.

Stover DG, Coloff JL, Barry WT, Brugge JS, Winer EP, Selfors LM.

Clin Cancer Res. 2016 Dec 15;22(24):6039-6050. Epub 2016 Jun 21.

8.

Coping with the metabolic stress of leaving home.

Coloff JL, Brugge JS.

Cell Res. 2016 Jul;26(7):757-8. doi: 10.1038/cr.2016.61. Epub 2016 May 24.

9.

Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells.

Coloff JL, Murphy JP, Braun CR, Harris IS, Shelton LM, Kami K, Gygi SP, Selfors LM, Brugge JS.

Cell Metab. 2016 May 10;23(5):867-80. doi: 10.1016/j.cmet.2016.03.016. Epub 2016 Apr 28.

10.

Corrigendum: Chaperone-mediated autophagy degrades mutant p53.

Vakifahmetoglu-Norberg H, Kim M, Xia HG, Iwanicki MP, Ofengeim D, Coloff JL, Pan L, Ince TA, Kroemer G, Brugge JS, Yuan J.

Genes Dev. 2016 Apr 1;30(7):870. doi: 10.1101/gad.280453.116.

11.

Correction: Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.

Xia HG, Najafov A, Geng J, Galan-Acosta L, Han X, Guo Y, Shan B, Zhang Y, Norberg E, Zhang T, Pan L, Liu J, Coloff JL, Ofengeim D, Zhu H, Wu K, Cai Y, Yates JR, Zhu Z, Yuan J, Vakifahmetoglu-Norberg H.

J Cell Biol. 2016 Mar 28;212(7):881-2. doi: 10.1083/jcb.20150304403082016c. Epub 2016 Mar 21. No abstract available.

12.

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.

Xia HG, Najafov A, Geng J, Galan-Acosta L, Han X, Guo Y, Shan B, Zhang Y, Norberg E, Zhang T, Pan L, Liu J, Coloff JL, Ofengeim D, Zhu H, Wu K, Cai Y, Yates JR, Zhu Z, Yuan J, Vakifahmetoglu-Norberg H.

J Cell Biol. 2015 Aug 31;210(5):705-16. doi: 10.1083/jcb.201503044. Erratum in: J Cell Biol. 2016 Mar 28;212(7):881-2.

13.

HIF1α and HIF2α exert distinct nutrient preferences in renal cells.

Arreola A, Cowey CL, Coloff JL, Rathmell JC, Rathmell WK.

PLoS One. 2014 May 30;9(5):e98705. doi: 10.1371/journal.pone.0098705. eCollection 2014.

14.

Combining amine metabolomics and quantitative proteomics of cancer cells using derivatization with isobaric tags.

Murphy JP, Everley RA, Coloff JL, Gygi SP.

Anal Chem. 2014 Apr 1;86(7):3585-93. doi: 10.1021/ac500153a. Epub 2014 Mar 20.

15.

Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.

Parkhitko AA, Priolo C, Coloff JL, Yun J, Wu JJ, Mizumura K, Xu W, Malinowska IA, Yu J, Kwiatkowski DJ, Locasale JW, Asara JM, Choi AM, Finkel T, Henske EP.

Mol Cancer Res. 2014 Jan;12(1):48-57. doi: 10.1158/1541-7786.MCR-13-0258-T. Epub 2013 Dec 2.

16.

Chaperone-mediated autophagy degrades mutant p53.

Vakifahmetoglu-Norberg H, Kim M, Xia HG, Iwanicki MP, Ofengeim D, Coloff JL, Pan L, Ince TA, Kroemer G, Brugge JS, Yuan J.

Genes Dev. 2013 Aug 1;27(15):1718-30. doi: 10.1101/gad.220897.113. Erratum in: Genes Dev. 2016 Apr 1;30(7):870. Genes Dev. 2013 Sep 1;27(17):1947.

17.

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.

Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, DePinho RA.

Cell. 2012 Apr 27;149(3):656-70. doi: 10.1016/j.cell.2012.01.058.

18.

Extracellular matrix regulation of metabolism and implications for tumorigenesis.

Grassian AR, Coloff JL, Brugge JS.

Cold Spring Harb Symp Quant Biol. 2011;76:313-24. doi: 10.1101/sqb.2011.76.010967. Epub 2011 Nov 21. Review.

PMID:
22105806
19.

Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation.

Grassian AR, Metallo CM, Coloff JL, Stephanopoulos G, Brugge JS.

Genes Dev. 2011 Aug 15;25(16):1716-33. doi: 10.1101/gad.16771811.

20.

Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.

Coloff JL, Macintyre AN, Nichols AG, Liu T, Gallo CA, Plas DR, Rathmell JC.

Cancer Res. 2011 Aug 1;71(15):5204-13. doi: 10.1158/0008-5472.CAN-10-4531. Epub 2011 Jun 13.

21.

Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability.

Horn SR, Thomenius MJ, Johnson ES, Freel CD, Wu JQ, Coloff JL, Yang CS, Tang W, An J, Ilkayeva OR, Rathmell JC, Newgard CB, Kornbluth S.

Mol Biol Cell. 2011 Apr 15;22(8):1207-16. doi: 10.1091/mbc.E10-07-0567. Epub 2011 Feb 16.

22.

Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.

Coloff JL, Mason EF, Altman BJ, Gerriets VA, Liu T, Nichols AN, Zhao Y, Wofford JA, Jacobs SR, Ilkayeva O, Garrison SP, Zambetti GP, Rathmell JC.

J Biol Chem. 2011 Feb 18;286(7):5921-33. doi: 10.1074/jbc.M110.179101. Epub 2010 Dec 15.

23.

Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis.

Altman BJ, Jacobs SR, Mason EF, Michalek RD, MacIntyre AN, Coloff JL, Ilkayeva O, Jia W, He YW, Rathmell JC.

Oncogene. 2011 Apr 21;30(16):1855-67. doi: 10.1038/onc.2010.561. Epub 2010 Dec 13.

24.

Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl.

Mason EF, Zhao Y, Goraksha-Hicks P, Coloff JL, Gannon H, Jones SN, Rathmell JC.

Cancer Res. 2010 Oct 15;70(20):8066-76. doi: 10.1158/0008-5472.CAN-10-0608. Epub 2010 Sep 28.

25.

The c-Jun NH2-terminal kinase 2 plays a dominant role in human epidermal neoplasia.

Ke H, Harris R, Coloff JL, Jin JY, Leshin B, Miliani de Marval P, Tao S, Rathmell JC, Hall RP, Zhang JY.

Cancer Res. 2010 Apr 15;70(8):3080-8. doi: 10.1158/0008-5472.CAN-09-2923. Epub 2010 Mar 30.

26.

Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis.

Altman BJ, Wofford JA, Zhao Y, Coloff JL, Ferguson EC, Wieman HL, Day AE, Ilkayeva O, Rathmell JC.

Mol Biol Cell. 2009 Feb;20(4):1180-91. doi: 10.1091/mbc.E08-08-0829. Epub 2008 Dec 24.

27.

Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation.

Zhao Y, Coloff JL, Ferguson EC, Jacobs SR, Cui K, Rathmell JC.

J Biol Chem. 2008 Dec 26;283(52):36344-53. doi: 10.1074/jbc.M803580200. Epub 2008 Nov 6.

28.

Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival.

Maciver NJ, Jacobs SR, Wieman HL, Wofford JA, Coloff JL, Rathmell JC.

J Leukoc Biol. 2008 Oct;84(4):949-57. doi: 10.1189/jlb.0108024. Epub 2008 Jun 24. Review.

29.

Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

Zhao Y, Altman BJ, Coloff JL, Herman CE, Jacobs SR, Wieman HL, Wofford JA, Dimascio LN, Ilkayeva O, Kelekar A, Reya T, Rathmell JC.

Mol Cell Biol. 2007 Jun;27(12):4328-39. Epub 2007 Mar 19.

30.

Metabolic regulation of Akt: roles reversed.

Coloff JL, Rathmell JC.

J Cell Biol. 2006 Dec 18;175(6):845-7. Epub 2006 Dec 11.

31.

Distinct rates of palmitate turnover on membrane-bound cellular and oncogenic H-ras.

Baker TL, Zheng H, Walker J, Coloff JL, Buss JE.

J Biol Chem. 2003 May 23;278(21):19292-300. Epub 2003 Mar 17.

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