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Items: 47

1.

The concomitant loss of APC and HNF4α in adult hepatocytes does not contribute to hepatocarcinogenesis driven by β-catenin activation.

Sartor C, Bachelot L, Godard C, Lager F, Renault G, Gonzalez FJ, Perret C, Gougelet A, Colnot S.

Liver Int. 2019 Feb 5. doi: 10.1111/liv.14068. [Epub ahead of print]

PMID:
30721564
2.

Potentials of CRISPR in liver research and therapy.

Loesch R, Desbois-Mouthon C, Colnot S.

Clin Res Hepatol Gastroenterol. 2019 Feb;43(1):5-11. doi: 10.1016/j.clinre.2018.05.001. Epub 2018 Jun 5.

PMID:
29884474
3.

β-catenin-activated hepatocellular carcinomas are addicted to fatty acids.

Senni N, Savall M, Cabrerizo Granados D, Alves-Guerra MC, Sartor C, Lagoutte I, Gougelet A, Terris B, Gilgenkrantz H, Perret C, Colnot S, Bossard P.

Gut. 2019 Feb;68(2):322-334. doi: 10.1136/gutjnl-2017-315448. Epub 2018 Apr 12.

PMID:
29650531
4.

Focusing on beta-catenin activating mutations to refine liver tumor profiling.

Colnot S.

Hepatology. 2016 Dec;64(6):1850-1852. doi: 10.1002/hep.28761. Epub 2016 Oct 4. No abstract available.

PMID:
27515244
5.

Coordinate regulation of Cyp2e1 by β-catenin- and hepatocyte nuclear factor 1α-dependent signaling.

Groll N, Petrikat T, Vetter S, Colnot S, Weiss F, Poetz O, Joos TO, Rothbauer U, Schwarz M, Braeuning A.

Toxicology. 2016 Mar 28;350-352:40-8. doi: 10.1016/j.tox.2016.05.004. Epub 2016 May 3.

PMID:
27153753
6.

Generation of Mice with Hepatocyte-Specific Conditional Deletion of Notum.

Canal F, Charawi S, Grimber G, Houbron C, Drouet V, Colnot S, Terris B, Cavard C, Perret C.

PLoS One. 2016 Mar 14;11(3):e0150997. doi: 10.1371/journal.pone.0150997. eCollection 2016.

7.

Role of β-catenin in development of bile ducts.

Cordi S, Godard C, Saandi T, Jacquemin P, Monga SP, Colnot S, Lemaigre FP.

Differentiation. 2016 Jan-Mar;91(1-3):42-9. doi: 10.1016/j.diff.2016.02.001. Epub 2016 Feb 5.

8.

Tumor promotion and inhibition by phenobarbital in livers of conditional Apc-deficient mice.

Braeuning A, Gavrilov A, Geissler M, Wenz C, Colnot S, Templin MF, Metzger U, Römer M, Zell A, Schwarz M.

Arch Toxicol. 2016 Jun;90(6):1481-94. doi: 10.1007/s00204-016-1667-1. Epub 2016 Feb 2.

PMID:
26838046
9.

Hepatocellular carcinoma diagnosis: Circulating microRNAs emerge as robust biomarkers.

Gougelet A, Colnot S.

Clin Res Hepatol Gastroenterol. 2016 Sep;40(4):367-9. doi: 10.1016/j.clinre.2015.12.010. Epub 2016 Jan 26. No abstract available.

PMID:
26823043
10.

LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis.

Just PA, Poncy A, Charawi S, Dahmani R, Traore M, Dumontet T, Drouet V, Dumont F, Gilgenkrantz H, Colnot S, Terris B, Coulouarn C, Lemaigre F, Perret C.

PLoS One. 2015 Dec 21;10(12):e0145400. doi: 10.1371/journal.pone.0145400. eCollection 2015.

11.

APC is required for muscle stem cell proliferation and skeletal muscle tissue repair.

Parisi A, Lacour F, Giordani L, Colnot S, Maire P, Le Grand F.

J Cell Biol. 2015 Aug 31;210(5):717-26. doi: 10.1083/jcb.201501053. Epub 2015 Aug 24.

12.

Antitumour activity of an inhibitor of miR-34a in liver cancer with β-catenin-mutations.

Gougelet A, Sartor C, Bachelot L, Godard C, Marchiol C, Renault G, Tores F, Nitschke P, Cavard C, Terris B, Perret C, Colnot S.

Gut. 2016 Jun;65(6):1024-34. doi: 10.1136/gutjnl-2014-308969. Epub 2015 Mar 19.

13.

Hippo/YAP, β-catenin, and the cancer cell: a "ménage à trois" in hepatoblastoma.

Sylvester KG, Colnot S.

Gastroenterology. 2014 Sep;147(3):562-5. doi: 10.1053/j.gastro.2014.07.026. Epub 2014 Jul 27. No abstract available.

PMID:
25072176
14.

T-cell factor 4 and β-catenin chromatin occupancies pattern zonal liver metabolism in mice.

Gougelet A, Torre C, Veber P, Sartor C, Bachelot L, Denechaud PD, Godard C, Moldes M, Burnol AF, Dubuquoy C, Terris B, Guillonneau F, Ye T, Schwarz M, Braeuning A, Perret C, Colnot S.

Hepatology. 2014 Jun;59(6):2344-57. doi: 10.1002/hep.26924. Epub 2014 Apr 14.

PMID:
24214913
15.

[microRNA: new diagnostic and therapeutic tools in liver disease?].

Gougelet A, Colnot S.

Med Sci (Paris). 2013 Oct;29(10):861-7. doi: 10.1051/medsci/20132910013. Epub 2013 Oct 18. Review. French.

16.

Editing liver tumours.

Colnot S, Fortes P.

Gut. 2014 May;63(5):709-10. doi: 10.1136/gutjnl-2013-305334. Epub 2013 Jul 22. No abstract available.

PMID:
23878166
17.

MicroRNA-feedback loop as a key modulator of liver tumorigenesis and inflammation.

Gougelet A, Colnot S.

World J Gastroenterol. 2013 Jan 28;19(4):440-4. doi: 10.3748/wjg.v19.i4.440.

18.

Dual-specificity phosphatases are targets of the Wnt/β-catenin pathway and candidate mediators of β-catenin/Ras signaling interactions.

Zeller E, Mock K, Horn M, Colnot S, Schwarz M, Braeuning A.

Biol Chem. 2012 Oct;393(10):1183-91. doi: 10.1515/hsz-2012-0130.

PMID:
23089536
19.

A Complex Interplay between Wnt/β-Catenin Signalling and the Cell Cycle in the Adult Liver.

Gougelet A, Colnot S.

Int J Hepatol. 2012;2012:816125. doi: 10.1155/2012/816125. Epub 2012 Sep 3.

20.

The four and a half LIM-only protein 2 regulates liver homeostasis and contributes to carcinogenesis.

Nouët Y, Dahan J, Labalette C, Levillayer F, Julien B, Jouvion G, Cairo S, Vives FL, Ribeiro A, Huerre M, Colnot S, Perret C, Nhieu JT, Tordjmann T, Buendia MA, Wei Y.

J Hepatol. 2012 Nov;57(5):1029-36. doi: 10.1016/j.jhep.2012.06.035. Epub 2012 Jul 11.

PMID:
22796152
21.

Oncogenic β-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice.

Anson M, Crain-Denoyelle AM, Baud V, Chereau F, Gougelet A, Terris B, Yamagoe S, Colnot S, Viguier M, Perret C, Couty JP.

J Clin Invest. 2012 Feb;122(2):586-99. doi: 10.1172/JCI43937. Epub 2012 Jan 17.

22.

The transforming growth factor-α and cyclin D1 genes are direct targets of β-catenin signaling in hepatocyte proliferation.

Torre C, Benhamouche S, Mitchell C, Godard C, Veber P, Letourneur F, Cagnard N, Jacques S, Finzi L, Perret C, Colnot S.

J Hepatol. 2011 Jul;55(1):86-95. doi: 10.1016/j.jhep.2010.10.021. Epub 2010 Nov 30.

PMID:
21145869
23.

Molecular determinants of liver zonation.

Torre C, Perret C, Colnot S.

Prog Mol Biol Transl Sci. 2010;97:127-50. doi: 10.1016/B978-0-12-385233-5.00005-2. Review.

PMID:
21074732
24.

Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.

Labalette C, Nouët Y, Levillayer F, Colnot S, Chen J, Claude V, Huerre M, Perret C, Buendia MA, Wei Y.

PLoS One. 2010 Apr 28;5(4):e10371. doi: 10.1371/journal.pone.0010371.

25.

Transcription dynamics in a physiological process: β-catenin signaling directs liver metabolic zonation.

Torre C, Perret C, Colnot S.

Int J Biochem Cell Biol. 2011 Feb;43(2):271-8. doi: 10.1016/j.biocel.2009.11.004. Epub 2009 Nov 13. Review.

PMID:
19914393
26.

Proteomic analysis of beta-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway.

Chafey P, Finzi L, Boisgard R, Caüzac M, Clary G, Broussard C, Pégorier JP, Guillonneau F, Mayeux P, Camoin L, Tavitian B, Colnot S, Perret C.

Proteomics. 2009 Aug;9(15):3889-900. doi: 10.1002/pmic.200800609.

PMID:
19639598
27.

A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation.

Andreu P, Peignon G, Slomianny C, Taketo MM, Colnot S, Robine S, Lamarque D, Laurent-Puig P, Perret C, Romagnolo B.

Dev Biol. 2008 Dec 15;324(2):288-96. doi: 10.1016/j.ydbio.2008.09.027. Epub 2008 Oct 4.

28.

Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology.

Cavard C, Colnot S, Audard V, Benhamouche S, Finzi L, Torre C, Grimber G, Godard C, Terris B, Perret C.

Future Oncol. 2008 Oct;4(5):647-60. doi: 10.2217/14796694.4.5.647. Review.

PMID:
18922122
29.

The H19 locus acts in vivo as a tumor suppressor.

Yoshimizu T, Miroglio A, Ripoche MA, Gabory A, Vernucci M, Riccio A, Colnot S, Godard C, Terris B, Jammes H, Dandolo L.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12417-22. doi: 10.1073/pnas.0801540105. Epub 2008 Aug 21.

30.

Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate.

Decaens T, Godard C, de Reyniès A, Rickman DS, Tronche F, Couty JP, Perret C, Colnot S.

Hepatology. 2008 Jan;47(1):247-58.

PMID:
18038450
31.

[Wnt/beta-catenin pathway and liver metabolic zonation: a new player for an old concept].

Benhamouche S, Decaens T, Perret C, Colnot S.

Med Sci (Paris). 2006 Nov;22(11):904-6. French. No abstract available.

32.

Apc tumor suppressor gene is the "zonation-keeper" of mouse liver.

Benhamouche S, Decaens T, Godard C, Chambrey R, Rickman DS, Moinard C, Vasseur-Cognet M, Kuo CJ, Kahn A, Perret C, Colnot S.

Dev Cell. 2006 Jun;10(6):759-70.

33.

Identification of the IFITM family as a new molecular marker in human colorectal tumors.

Andreu P, Colnot S, Godard C, Laurent-Puig P, Lamarque D, Kahn A, Perret C, Romagnolo B.

Cancer Res. 2006 Feb 15;66(4):1949-55.

34.

[Activating a beta-catenin signal in the liver is oncogenic].

Colnot S, Decaens T, Perret C.

Med Sci (Paris). 2005 Apr;21(4):355-7. French. No abstract available.

35.

Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.

Andreu P, Colnot S, Godard C, Gad S, Chafey P, Niwa-Kawakita M, Laurent-Puig P, Kahn A, Robine S, Perret C, Romagnolo B.

Development. 2005 Mar;132(6):1443-51. Epub 2005 Feb 16.

36.

Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas.

Colnot S, Decaens T, Niwa-Kawakita M, Godard C, Hamard G, Kahn A, Giovannini M, Perret C.

Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17216-21. Epub 2004 Nov 24.

37.

Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers.

Colnot S, Niwa-Kawakita M, Hamard G, Godard C, Le Plenier S, Houbron C, Romagnolo B, Berrebi D, Giovannini M, Perret C.

Lab Invest. 2004 Dec;84(12):1619-30.

38.

Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles.

Leneuve P, Colnot S, Hamard G, Francis F, Niwa-Kawakita M, Giovannini M, Holzenberger M.

Nucleic Acids Res. 2003 Mar 1;31(5):e21.

39.

Transgenic analysis of the response of the rat calbindin-D 9k gene to vitamin D.

Colnot S, Ovejero C, Romagnolo B, Porteu A, Lacourte P, Thomasset M, Perret C.

Endocrinology. 2000 Jul;141(7):2301-8.

PMID:
10875229
40.

Intestinal expression of the calbindin-D9K gene in transgenic mice. Requirement for a Cdx2-binding site in a distal activator region.

Colnot S, Romagnolo B, Lambert M, Cluzeaud F, Porteu A, Vandewalle A, Thomasset M, Kahn A, Perret C.

J Biol Chem. 1998 Nov 27;273(48):31939-46.

41.

Control of nuclear transcription of vitamin D-dependent genes by vitamin D.

Perret C, Colnot S, Romagnolo B, Thomasset M.

Curr Opin Nephrol Hypertens. 1997 Jul;6(4):314-20. Review.

PMID:
9263679
42.

Tissue-specific and hormonal regulation of calbindin-D9K fusion genes in transgenic mice.

Romagnolo B, Cluzeaud F, Lambert M, Colnot S, Porteu A, Molina T, Tomasset M, Vandewalle A, Kahn A, Perret C.

J Biol Chem. 1996 Jul 12;271(28):16820-6.

43.

Functional and growth properties of a myometrial cell line derived from transgenic mice: effects of estradiol and antiestrogens.

Blin C, L'Horset F, Romagnolo B, Colnot S, Lambert M, Thomasset M, Kahn A, Vandewalle A, Perret C.

Endocrinology. 1996 Jun;137(6):2246-53.

PMID:
8641172
44.

cis-Acting elements and transcription factors involved in the intestinal specific expression of the rat calbindin-D9K gene: binding of the intestine-specific transcription factor Cdx-2 to the TATA box.

Lambert M, Colnot S, Suh E, L'Horset F, Blin C, Calliot ME, Raymondjean M, Thomasset M, Traber PG, Perret C.

Eur J Biochem. 1996 Mar 15;236(3):778-88.

45.

Contrasting effects of tamoxifen and ICI 182 780 on estrogen-induced calbindin-D 9k gene expression in the uterus and in primary culture of myometrial cells.

Blin C, L'Horset F, Leclerc T, Lambert M, Colnot S, Thomasset M, Perret C.

J Steroid Biochem Mol Biol. 1995 Oct;55(1):1-7.

PMID:
7577712
46.

Identification of DNA sequences that bind retinoid X receptor-1,25(OH)2D3-receptor heterodimers with high affinity.

Colnot S, Lambert M, Blin C, Thomasset M, Perret C.

Mol Cell Endocrinol. 1995 Aug 30;113(1):89-98.

PMID:
8674817
47.

Calbindin-D9k gene expression in the uterus: study of the two messenger ribonucleic acid species and analysis of an imperfect estrogen-responsive element.

L'Horset F, Blin C, Colnot S, Lambert M, Thomasset M, Perret C.

Endocrinology. 1994 Jan;134(1):11-8.

PMID:
7506202

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