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Items: 10


Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5.

Griffin EA Jr, Melas PA, Zhou R, Li Y, Mercado P, Kempadoo KA, Stephenson S, Colnaghi L, Taylor K, Hu MC, Kandel ER, Kandel DB.

Sci Adv. 2017 Nov 1;3(11):e1701682. doi: 10.1126/sciadv.1701682. eCollection 2017 Nov.


Social Involvement Modulates the Response to Novel and Adverse Life Events in Mice.

Colnaghi L, Clemenza K, Groleau SE, Weiss S, Snyder AM, Lopez-Rosas M, Levine AA.

PLoS One. 2016 Sep 15;11(9):e0163077. doi: 10.1371/journal.pone.0163077. eCollection 2016.


The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton.

Stephan JS, Fioriti L, Lamba N, Colnaghi L, Karl K, Derkatch IL, Kandel ER.

Cell Rep. 2015 Jun 23;11(11):1772-85. doi: 10.1016/j.celrep.2015.04.060. Epub 2015 Jun 11.


SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3.

Drisaldi B, Colnaghi L, Fioriti L, Rao N, Myers C, Snyder AM, Metzger DJ, Tarasoff J, Konstantinov E, Fraser PE, Manley JL, Kandel ER.

Cell Rep. 2015 Jun 23;11(11):1694-702. doi: 10.1016/j.celrep.2015.04.061. Epub 2015 Jun 11.


The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3.

Fioriti L, Myers C, Huang YY, Li X, Stephan JS, Trifilieff P, Colnaghi L, Kosmidis S, Drisaldi B, Pavlopoulos E, Kandel ER.

Neuron. 2015 Jun 17;86(6):1433-48. doi: 10.1016/j.neuron.2015.05.021. Epub 2015 Jun 11.


ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.

Chen YH, Jones MJ, Yin Y, Crist SB, Colnaghi L, Sims RJ 3rd, Rothenberg E, Jallepalli PV, Huang TT.

Mol Cell. 2015 Apr 16;58(2):323-38. doi: 10.1016/j.molcel.2015.02.031. Epub 2015 Apr 2.


D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus.

Huang YY, Levine A, Kandel DB, Yin D, Colnaghi L, Drisaldi B, Kandel ER.

Learn Mem. 2014 Feb 18;21(3):153-60. doi: 10.1101/lm.032292.113.


The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.

Piatkov KI, Colnaghi L, Békés M, Varshavsky A, Huang TT.

Mol Cell. 2012 Dec 28;48(6):926-33. doi: 10.1016/j.molcel.2012.10.012. Epub 2012 Nov 15.


Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability.

Jones MJ, Colnaghi L, Huang TT.

EMBO J. 2012 Feb 15;31(4):908-18. doi: 10.1038/emboj.2011.457. Epub 2011 Dec 13.


Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair.

Colnaghi L, Jones MJ, Cotto-Rios XM, Schindler D, Hanenberg H, Huang TT.

Blood. 2011 Feb 17;117(7):2247-56. doi: 10.1182/blood-2010-07-295758. Epub 2010 Oct 22.

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