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[Should patients with type 2 diabetes be screened for lower extremity arterial disease?]

Buso G, Collet TH, Wojtusciszyn A, Maufus M, Ney B, Mazzolai L.

Rev Med Suisse. 2019 Dec 4;15(674):2236-2240. French.


Molecular signaling of G-protein-coupled receptor in chronic heart failure and associated complications.

Altamish M, Samuel VP, Dahiya R, Singh Y, Deb PK, Bakshi HA, Tambuwala MM, Chellappan DK, Collet T, Dua K, Gupta G.

Drug Dev Res. 2019 Nov 30. doi: 10.1002/ddr.21627. [Epub ahead of print] Review.


A randomized, double-blind placebo-controlled study of intranasal standardized cinnamon bark extract for seasonal allergic rhinitis.

Steels E, Steels E, Deshpande P, Thakurdesai P, Dighe S, Collet T.

Complement Ther Med. 2019 Dec;47:102198. doi: 10.1016/j.ctim.2019.102198. Epub 2019 Sep 24.


Emerging Complexity and the Need for Advanced Drug Delivery in Targeting Candida Species.

Wadhwa R, Pandey P, Gupta G, Aggarwal T, Kumar N, Mehta M, Satija S, Gulati M, Madan J, Dureja H, Balusamy SR, Perumalsamy H, K Maurya P, Collet T, Tambuwala MM, Hansbro PM, Chellappan DK, Dua K.

Curr Top Med Chem. 2019 Oct 25. doi: 10.2174/1568026619666191026105308. [Epub ahead of print]


Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study.

Gonzalez Rodriguez E, Stuber M, Del Giovane C, Feller M, Collet TH, Löwe AL, Blum MR, van Vliet NA, van Heemst D, Kearney PM, Gussekloo J, Mooijaart S, Westendorp RGJ, Stott DJ, Aeberli D, Bauer DC, Hans D, Rodondi N.

J Clin Endocrinol Metab. 2019 Nov 8. pii: dgz058. doi: 10.1210/clinem/dgz058. [Epub ahead of print]


The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress.

Dua K, Wadhwa R, Singhvi G, Rapalli V, Shukla SD, Shastri MD, Gupta G, Satija S, Mehta M, Khurana N, Awasthi R, Maurya PK, Thangavelu L, S R, Tambuwala MM, Collet T, Hansbro PM, Chellappan DK.

Drug Dev Res. 2019 Sep;80(6):714-730. doi: 10.1002/ddr.21571. Epub 2019 Jul 16. Review.


Therapeutic potential of Artemisia vulgaris: An insight into underlying immunological mechanisms.

Soon L, Ng PQ, Chellian J, Madheswaran T, Panneerselvam J, Gupta G, Nammi S, Hansbro NG, Hsu A, Dureja H, Mehta M, Satija S, Hansbro PM, Dua K, Collet T, Chellappan DK.

J Environ Pathol Toxicol Oncol. 2019;38(3):205-216. doi: 10.1615/JEnvironPatholToxicolOncol.2019029397. Review.


Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism.

Mooijaart SP, Du Puy RS, Stott DJ, Kearney PM, Rodondi N, Westendorp RGJ, den Elzen WPJ, Postmus I, Poortvliet RKE, van Heemst D, van Munster BC, Peeters RP, Ford I, Kean S, Messow CM, Blum MR, Collet TH, Watt T, Dekkers OM, Jukema JW, Smit JWA, Langhorne P, Gussekloo J.

JAMA. 2019 Oct 30:1-11. doi: 10.1001/jama.2019.17274. [Epub ahead of print]


Interactions between microbiome and lungs: Paving new paths for microbiome based bio-engineered drug delivery systems in chronic respiratory diseases.

Chellappan DK, Sze Ning QL, Su Min SK, Bin SY, Chern PJ, Shi TP, Ee Mei SW, Yee TH, Qi OJ, Thangavelu L, Rajeshkumar S, Negi P, Chellian J, Wadhwa R, Gupta G, Collet T, Hansbro PM, Dua K.

Chem Biol Interact. 2019 Sep 1;310:108732. doi: 10.1016/j.cbi.2019.108732. Epub 2019 Jul 2. Review.


Prognostic value of total testosterone levels in patients with acute coronary syndromes.

Gencer B, Vuilleumier N, Nanchen D, Collet TH, Klingenberg R, Räber L, Auer R, Carballo D, Carballo S, Aghlmandi S, Heg D, Windecker S, Lüscher TF, Matter CM, Rodondi N, Mach F.

Eur J Prev Cardiol. 2019 Jun 1:2047487319853343. doi: 10.1177/2047487319853343. [Epub ahead of print]


Antiretroviral agents in pre-exposure prophylaxis: emerging and advanced trends in HIV prevention.

Yap PK, Loo Xin GL, Tan YY, Chellian J, Gupta G, Liew YK, Collet T, Dua K, Chellappan DK.

J Pharm Pharmacol. 2019 Sep;71(9):1339-1352. doi: 10.1111/jphp.13107. Epub 2019 May 29. Review.


Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases.

Mehta M, Deeksha, Tewari D, Gupta G, Awasthi R, Singh H, Pandey P, Chellappan DK, Wadhwa R, Collet T, Hansbro PM, Kumar SR, Thangavelu L, Negi P, Dua K, Satija S.

Chem Biol Interact. 2019 Aug 1;308:206-215. doi: 10.1016/j.cbi.2019.05.028. Epub 2019 May 25. Review.


Recent update on anti-dengue drug discovery.

Dighe SN, Ekwudu O, Dua K, Chellappan DK, Katavic PL, Collet TA.

Eur J Med Chem. 2019 Aug 15;176:431-455. doi: 10.1016/j.ejmech.2019.05.010. Epub 2019 May 12. Review.


Identification of biomarkers and genetic approaches toward chronic obstructive pulmonary disease.

Wadhwa R, Aggarwal T, Malyla V, Kumar N, Gupta G, Chellappan DK, Dureja H, Mehta M, Satija S, Gulati M, Maurya PK, Collet T, Hansbro PM, Dua K.

J Cell Physiol. 2019 Aug;234(10):16703-16723. doi: 10.1002/jcp.28482. Epub 2019 Mar 25. Review.


Current Status on Immunological Therapies for Type 1 Diabetes Mellitus.

Xin GLL, Khee YP, Ying TY, Chellian J, Gupta G, Kunnath AP, Nammi S, Collet T, Hansbro PM, Dua K, Chellappan DK.

Curr Diab Rep. 2019 Mar 23;19(5):22. doi: 10.1007/s11892-019-1144-3. Review.


Interactions with the macrophages: An emerging targeted approach using novel drug delivery systems in respiratory diseases.

Mehta M, Deeksha, Sharma N, Vyas M, Khurana N, Maurya PK, Singh H, Andreoli de Jesus TP, Dureja H, Chellappan DK, Gupta G, Wadhwa R, Collet T, Hansbro PM, Dua K, Satija S.

Chem Biol Interact. 2019 May 1;304:10-19. doi: 10.1016/j.cbi.2019.02.021. Epub 2019 Mar 5. Review.


Nanoparticle-based therapies as a modality in treating wounds and preventing biofilm.

Dua K, Gupta G, Chellapan DK, Bebawy M, Collet T.

Panminerva Med. 2018 Dec;60(4):237-238. doi: 10.23736/S0031-0808.18.03435-3. No abstract available.


Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems.

Dua K, Malyla V, Singhvi G, Wadhwa R, Krishna RV, Shukla SD, Shastri MD, Chellappan DK, Maurya PK, Satija S, Mehta M, Gulati M, Hansbro N, Collet T, Awasthi R, Gupta G, Hsu A, Hansbro PM.

Chem Biol Interact. 2019 Feb 1;299:168-178. doi: 10.1016/j.cbi.2018.12.009. Epub 2018 Dec 13. Review.


Molecular modulators of celastrol as the keystones for its diverse pharmacological activities.

Ng SW, Chan Y, Chellappan DK, Madheswaran T, Zeeshan F, Chan YL, Collet T, Gupta G, Oliver BG, Wark P, Hansbro N, Hsu A, Hansbro PM, Dua K, Panneerselvam J.

Biomed Pharmacother. 2019 Jan;109:1785-1792. doi: 10.1016/j.biopha.2018.11.051. Epub 2018 Nov 26. Review.


The Reduction of Visceral Adipose Tissue after Roux-en-Y Gastric Bypass Is more Pronounced in Patients with Impaired Glucose Metabolism.

Favre L, Marino L, Roth A, Acierno J Jr, Hans D, Demartines N, Pitteloud N, Suter M, Collet TH.

Obes Surg. 2018 Dec;28(12):4006-4013. doi: 10.1007/s11695-018-3455-x.


Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial.

Blum MR, Gencer B, Adam L, Feller M, Collet TH, da Costa BR, Moutzouri E, Dopheide J, Depairon M, Sykiotis GP, Kearney P, Gussekloo J, Westendorp R, Stott DJ, Bauer DC, Rodondi N.

J Clin Endocrinol Metab. 2018 Aug 1;103(8):2988-2997. doi: 10.1210/jc.2018-00279.


Initial evaluation of thyroid dysfunction - Are simultaneous TSH and fT4 tests necessary?

Schneider C, Feller M, Bauer DC, Collet TH, da Costa BR, Auer R, Peeters RP, Brown SJ, Bremner AP, O'Leary PC, Feddema P, Leedman PJ, Aujesky D, Walsh JP, Rodondi N.

PLoS One. 2018 Apr 30;13(4):e0196631. doi: 10.1371/journal.pone.0196631. eCollection 2018.


Diagnosing Acute Mountain Sickness-Reply.

Collet TH, Meier D, Sartori C.

JAMA. 2018 Apr 10;319(14):1509-1510. doi: 10.1001/jama.2018.0236. No abstract available.


Thyroid Dysfunction and Anemia: A Prospective Cohort Study and a Systematic Review.

Floriani C, Feller M, Aubert CE, M'Rabet-Bensalah K, Collet TH, den Elzen WPJ, Bauer DC, Angelillo-Scherrer A, Aujesky D, Rodondi N.

Thyroid. 2018 May;28(5):575-582. doi: 10.1089/thy.2017.0480. Epub 2018 Apr 30.


Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study.

O Riordan D, Aubert CE, Walsh KA, Van Dorland A, Rodondi N, Du Puy RS, Poortvliet RKE, Gussekloo J, Sinnott C, Byrne S, Galvin R, Jukema JW, Mooijaart SP, Baumgartner C, McCarthy V, Walsh EK, Collet TH, Dekkers OM, Blum MR, Kearney PM.

BMJ Open. 2018 Mar 22;8(3):e019003. doi: 10.1136/bmjopen-2017-019003.


[Management of obesity-associated dyslipidemia : an approach based on food choices].

Mbundu Ilunga R, Helbling C, Favre L, Collet TH.

Rev Med Suisse. 2018 Mar 21;14(599):627-632. French.


[Current update on PCKS9 inhibitors].

Gencer B, Nanchen D, Collet TH, Rodondi N, Mach F.

Rev Med Suisse. 2018 Feb 28;14(596):482-486. French.


[Subclinical hypothyroidism : should we still treat elderly patients? Clinical implications of a new trial in primary care].

Collet TH, Sykiotis GP, Aubert CE, Baumgartner C, Blum MR, Feller M, Stettler C, Rodondi N.

Rev Med Suisse. 2018 Feb 28;14(596):470-474. French.


[Statin-associated muscle symptoms : Current management in 2018].

Kosinski C, Tran C, Kuntzer T, Rodondi N, Collet TH.

Rev Med Suisse. 2018 Feb 28;14(596):462-469. French.


Midterm outcomes of titanium modular femoral necks in total hip arthroplasty.

Collet T, Atanasiu JP, de Cussac JB, Oufroukhi K, Bothorel H, Saffarini M, Badatcheff F.

Ann Transl Med. 2017 Oct;5(20):395. doi: 10.21037/atm.2017.07.36.


Does This Patient Have Acute Mountain Sickness?: The Rational Clinical Examination Systematic Review.

Meier D, Collet TH, Locatelli I, Cornuz J, Kayser B, Simel DL, Sartori C.

JAMA. 2017 Nov 14;318(18):1810-1819. doi: 10.1001/jama.2017.16192. Review. Erratum in: JAMA. 2018 Jun 19;319(23):2443.


Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation.

Baumgartner C, da Costa BR, Collet TH, Feller M, Floriani C, Bauer DC, Cappola AR, Heckbert SR, Ceresini G, Gussekloo J, den Elzen WPJ, Peeters RP, Luben R, Völzke H, Dörr M, Walsh JP, Bremner A, Iacoviello M, Macfarlane P, Heeringa J, Stott DJ, Westendorp RGJ, Khaw KT, Magnani JW, Aujesky D, Rodondi N; Thyroid Studies Collaboration.

Circulation. 2017 Nov 28;136(22):2100-2116. doi: 10.1161/CIRCULATIONAHA.117.028753. Epub 2017 Oct 23. Review.


Association between subclinical thyroid dysfunction and change in bone mineral density in prospective cohorts.

Segna D, Bauer DC, Feller M, Schneider C, Fink HA, Aubert CE, Collet TH, da Costa BR, Fischer K, Peeters RP, Cappola AR, Blum MR, van Dorland HA, Robbins J, Naylor K, Eastell R, Uitterlinden AG, Rivadeneira Ramirez F, Gogakos A, Gussekloo J, Williams GR, Schwartz A, Cauley JA, Aujesky DA, Bischoff-Ferrari HA, Rodondi N; Thyroid Studies Collaboration.

J Intern Med. 2018 Jan;283(1):56-72. doi: 10.1111/joim.12688. Epub 2017 Oct 16.


Evaluation of a melanocortin-4 receptor (MC4R) agonist (Setmelanotide) in MC4R deficiency.

Collet TH, Dubern B, Mokrosinski J, Connors H, Keogh JM, Mendes de Oliveira E, Henning E, Poitou-Bernert C, Oppert JM, Tounian P, Marchelli F, Alili R, Le Beyec J, Pépin D, Lacorte JM, Gottesdiener A, Bounds R, Sharma S, Folster C, Henderson B, O'Rahilly S, Stoner E, Gottesdiener K, Panaro BL, Cone RD, Clément K, Farooqi IS, Van der Ploeg LHT.

Mol Metab. 2017 Oct;6(10):1321-1329. doi: 10.1016/j.molmet.2017.06.015. Epub 2017 Jul 8.


A Metabolomic Signature of Acute Caloric Restriction.

Collet TH, Sonoyama T, Henning E, Keogh JM, Ingram B, Kelway S, Guo L, Farooqi IS.

J Clin Endocrinol Metab. 2017 Dec 1;102(12):4486-4495. doi: 10.1210/jc.2017-01020.


Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease.

Chaker L, Korevaar TIM, Rizopoulos D, Collet TH, Völzke H, Hofman A, Rodondi N, Cappola AR, Peeters RP, Franco OH.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2853-2861. doi: 10.1210/jc.2017-00410.


Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts.

Aubert CE, Floriani C, Bauer DC, da Costa BR, Segna D, Blum MR, Collet TH, Fink HA, Cappola AR, Syrogiannouli L, Peeters RP, Åsvold BO, den Elzen WPJ, Luben RN, Bremner AP, Gogakos A, Eastell R, Kearney PM, Hoff M, Le Blanc E, Ceresini G, Rivadeneira F, Uitterlinden AG, Khaw KT, Langhammer A, Stott DJ, Westendorp RGJ, Ferrucci L, Williams GR, Gussekloo J, Walsh JP, Aujesky D, Rodondi N; Thyroid Studies Collaboration.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2719-2728. doi: 10.1210/jc.2017-00294.


Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.

Stott DJ, Rodondi N, Kearney PM, Ford I, Westendorp RGJ, Mooijaart SP, Sattar N, Aubert CE, Aujesky D, Bauer DC, Baumgartner C, Blum MR, Browne JP, Byrne S, Collet TH, Dekkers OM, den Elzen WPJ, Du Puy RS, Ellis G, Feller M, Floriani C, Hendry K, Hurley C, Jukema JW, Kean S, Kelly M, Krebs D, Langhorne P, McCarthy G, McCarthy V, McConnachie A, McDade M, Messow M, O'Flynn A, O'Riordan D, Poortvliet RKE, Quinn TJ, Russell A, Sinnott C, Smit JWA, Van Dorland HA, Walsh KA, Walsh EK, Watt T, Wilson R, Gussekloo J; TRUST Study Group.

N Engl J Med. 2017 Jun 29;376(26):2534-2544. doi: 10.1056/NEJMoa1603825. Epub 2017 Apr 3.


Subclinical thyroid dysfunction and cardiovascular diseases: 2016 update.

Floriani C, Gencer B, Collet TH, Rodondi N.

Eur Heart J. 2018 Feb 14;39(7):503-507. doi: 10.1093/eurheartj/ehx050.


Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism - a randomised placebo controlled Trial (TRUST).

Stott DJ, Gussekloo J, Kearney PM, Rodondi N, Westendorp RG, Mooijaart S, Kean S, Quinn TJ, Sattar N, Hendry K, Du Puy R, Den Elzen WP, Poortvliet RK, Smit JW, Jukema JW, Dekkers OM, Blum M, Collet TH, McCarthy V, Hurley C, Byrne S, Browne J, Watt T, Bauer D, Ford I.

BMC Endocr Disord. 2017 Feb 3;17(1):6. doi: 10.1186/s12902-017-0156-8.


Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis.

Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT Jr, Psaty BM, Ferrucci L, Maciel RM, Westendorp RG, Jukema JW, Ceresini G, Imaizumi M, Hofman A, Bakker SJ, Franklyn JA, Khaw KT, Bauer DC, Walsh JP, Razvi S, Gussekloo J, Völzke H, Franco OH, Cappola AR, Rodondi N, Peeters RP; Thyroid Studies Collaboration.

J Clin Endocrinol Metab. 2016 Nov;101(11):4270-4282. Epub 2016 Sep 7.


Energy expenditure in frontotemporal dementia: a behavioural and imaging study.

Ahmed RM, Landin-Romero R, Collet TH, van der Klaauw AA, Devenney E, Henning E, Kiernan MC, Piguet O, Farooqi IS, Hodges JR.

Brain. 2017 Jan;140(1):171-183. doi: 10.1093/brain/aww263. Epub 2016 Oct 27.


Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies.

Rieben C, Segna D, da Costa BR, Collet TH, Chaker L, Aubert CE, Baumgartner C, Almeida OP, Hogervorst E, Trompet S, Masaki K, Mooijaart SP, Gussekloo J, Peeters RP, Bauer DC, Aujesky D, Rodondi N.

J Clin Endocrinol Metab. 2016 Dec;101(12):4945-4954. Epub 2016 Sep 30. Review.


Failure of sucrose replacement with the non-nutritive sweetener erythritol to alter GLP-1 or PYY release or test meal size in lean or obese people.

Overduin J, Collet TH, Medic N, Henning E, Keogh JM, Forsyth F, Stephenson C, Kanning MW, Ruijschop RMAJ, Farooqi IS, van der Klaauw AA.

Appetite. 2016 Dec 1;107:596-603. doi: 10.1016/j.appet.2016.09.009. Epub 2016 Sep 9.


Response to Tomoyuki Kawada, MD: Smoking, Systolic Blood Pressure, Fasting Plasma Glucose and Progression of Carotid Atherosclerosis.

Zingg S, Collet TH, Rodondi N.

Nicotine Tob Res. 2016 Jul;18(7):1681. doi: 10.1093/ntr/ntw027. Epub 2016 Mar 31. No abstract available.


The Sleep/Wake Cycle is Directly Modulated by Changes in Energy Balance.

Collet TH, van der Klaauw AA, Henning E, Keogh JM, Suddaby D, Dachi SV, Dunbar S, Kelway S, Dickson SL, Farooqi IS, Schmid SM.

Sleep. 2016 Sep 1;39(9):1691-700. doi: 10.5665/sleep.6094.


Polypharmacy and specific comorbidities in university primary care settings.

Aubert CE, Streit S, Da Costa BR, Collet TH, Cornuz J, Gaspoz JM, Bauer D, Aujesky D, Rodondi N.

Eur J Intern Med. 2016 Nov;35:35-42. doi: 10.1016/j.ejim.2016.05.022. Epub 2016 Jun 9.


Short medial approach harvesting of hamstring tendons.

Lanternier H, de Cussac JB, Collet T.

Orthop Traumatol Surg Res. 2016 Apr;102(2):269-72. doi: 10.1016/j.otsr.2015.12.004. Epub 2016 Feb 16.

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