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Items: 1 to 50 of 242

1.

Preclinical Studies of RUC-4, a Novel Platelet αIIbβ3 Antagonist, in Non-Human Primates and With Human Platelets.

Vootukuri S, Li J, Nedelman M, Thomas C, Jiang JK, Babayeva M, Coller BS.

J Clin Transl Sci. 2019 Jun;3(2-3):65-74. doi: 10.1017/cts.2019.382. Epub 2019 Jun 28.

PMID:
31544007
2.

Expand the scorecard for health-care reform to achieve a better result and enhance clinical and translational science.

Coller BS.

J Clin Transl Sci. 2018 Oct;2(5):276-279. doi: 10.1017/cts.2018.333. Epub 2018 Dec 7.

3.

Ethics of Human Genome Editing.

Coller BS.

Annu Rev Med. 2019 Jan 27;70:289-305. doi: 10.1146/annurev-med-112717-094629.

PMID:
30691366
4.

The Rockefeller University Clinical Scholars (KL2) Program 2006-2016.

Schlesinger SJ, Romanick M, Tobin JN, Brassil D, Kost RG, Devine R, O'Sullivan B, Vaughan RD, Liang Y, da Rosa JC, Williams M, Krueger JG, Coller BS.

J Clin Transl Sci. 2017 Oct;1(5):285-291. doi: 10.1017/cts.2017.308. Epub 2018 Feb 2.

5.

All nurses need to be research nurses.

Eckardt P, Hammer MJ, Barton-Burke M, McCabe M, Kovner CT, Behrens L, Reens H, Coller BS.

J Clin Transl Sci. 2017 Oct;1(5):269-270. doi: 10.1017/cts.2017.294. Epub 2017 Nov 16.

6.

αIIbβ3 binding to a fibrinogen fragment lacking the γ-chain dodecapeptide is activation dependent and EDTA inducible.

Zafar H, Shang Y, Li J, David GA 3rd, Fernandez JP, Molina H, Filizola M, Coller BS.

Blood Adv. 2017 Feb 22;1(7):417-428. doi: 10.1182/bloodadvances.2017004689. eCollection 2017 Feb 28.

7.

New methodologies to accurately assess circulating active transforming growth factor-β1 levels: implications for evaluating heart failure and the impact of left ventricular assist devices.

Mancini D, Monteagudo J, Suárez-Fariñas M, Bander J, Varshney R, Gonzalez J, Coller BS, Ahamed J.

Transl Res. 2018 Feb;192:15-29. doi: 10.1016/j.trsl.2017.10.006. Epub 2017 Nov 5.

8.

Informed consent for next-generation nucleotide sequencing studies: Aiding communication between participants and investigators.

Kost RG, Poppel SM, Coller BS.

J Clin Transl Sci. 2017 Apr;1(2):115-120. doi: 10.1017/cts.2016.21. Epub 2017 Feb 7.

9.

Toward Responsible Human Genome Editing.

Hynes RO, Coller BS, Porteus M.

JAMA. 2017 May 9;317(18):1829-1830. doi: 10.1001/jama.2017.4548. No abstract available.

PMID:
28395003
10.

From the Bench to the Barbershop: Community Engagement to Raise Awareness About Community-Acquired Methicillin-Resistant Staphylococcus aureus and Hepatitis C Virus Infection.

Leinberger-Jabari A, Kost RG, D'Orazio B, Burgess R, Khalida C, Tsang A, Mitchell D, Tomasz A, de Lencastre H, Pardos de la Gandara M, Evering TH, Holder T, Coller BS, Tobin JN.

Prog Community Health Partnersh. 2016;10(3):413-423. doi: 10.1353/cpr.2016.0048.

11.

Differences in prevalence of community-associated MRSA and MSSA among U.S. and non-U.S. born populations in six New York Community Health Centers.

Piper Jenks N, Pardos de la Gandara M, D'Orazio BM, Correa da Rosa J, Kost RG, Khalida C, Vasquez KS, Coffran C, Pastagia M, Evering TH, Parola C, Urban T, Salvato S, Barsanti F, Coller BS, Tobin JN.

Travel Med Infect Dis. 2016 Nov - Dec;14(6):551-560. doi: 10.1016/j.tmaid.2016.10.003. Epub 2016 Oct 20.

12.

Helping Basic Scientists Engage With Community Partners to Enrich and Accelerate Translational Research.

Kost RG, Leinberger-Jabari A, Evering TH, Holt PR, Neville-Williams M, Vasquez KS, Coller BS, Tobin JN.

Acad Med. 2017 Mar;92(3):374-379. doi: 10.1097/ACM.0000000000001200.

14.

Blood at 70: its roots in the history of hematology and its birth.

Coller BS.

Blood. 2015 Dec 10;126(24):2548-60. doi: 10.1182/blood-2015-09-659581.

15.

αIIbβ3: structure and function.

Coller BS.

J Thromb Haemost. 2015 Jun;13 Suppl 1:S17-25. doi: 10.1111/jth.12915. Review.

16.

Molecular Types of Methicillin-Resistant Staphylococcus aureus and Methicillin-Sensitive S. aureus Strains Causing Skin and Soft Tissue Infections and Nasal Colonization, Identified in Community Health Centers in New York City.

Pardos de la Gandara M, Raygoza Garay JA, Mwangi M, Tobin JN, Tsang A, Khalida C, D'Orazio B, Kost RG, Leinberger-Jabari A, Coffran C, Evering TH, Coller BS, Balachandra S, Urban T, Parola C, Salvato S, Jenks N, Wu D, Burgess R, Chung M, de Lencastre H, Tomasz A.

J Clin Microbiol. 2015 Aug;53(8):2648-58. doi: 10.1128/JCM.00591-15. Epub 2015 Jun 10.

17.

αIIbβ3 variants defined by next-generation sequencing: predicting variants likely to cause Glanzmann thrombasthenia.

Buitrago L, Rendon A, Liang Y, Simeoni I, Negri A; ThromboGenomics Consortium, Filizola M, Ouwehand WH, Coller BS.

Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):E1898-907. doi: 10.1073/pnas.1422238112. Epub 2015 Mar 31.

18.

Planning for the future workforce in hematology research.

Hoots WK, Abkowitz JL, Coller BS, DiMichele DM.

Blood. 2015 Apr 30;125(18):2745-52. doi: 10.1182/blood-2015-01-617811. Epub 2015 Mar 10.

19.

The Research Hospitalist: Protocol Enabler and Protector of Participant Safety.

O'Sullivan B, Coller BS.

Clin Transl Sci. 2015 Jun;8(3):174-6. doi: 10.1111/cts.12261. Epub 2015 Mar 9. No abstract available.

20.

The Rockefeller University Graduate Tracking Survey System.

Romanick M, Ng K, Lee G, Herbert M, Coller BS.

Clin Transl Sci. 2015 Aug;8(4):326-9. doi: 10.1111/cts.12238. Epub 2014 Nov 13.

21.

A data-rich recruitment core to support translational clinical research.

Kost RG, Corregano LM, Rainer TL, Melendez C, Coller BS.

Clin Transl Sci. 2015 Apr;8(2):91-9. doi: 10.1111/cts.12240. Epub 2014 Nov 10.

22.

RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction.

Li J, Vootukuri S, Shang Y, Negri A, Jiang JK, Nedelman M, Diacovo TG, Filizola M, Thomas CJ, Coller BS.

Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2321-9. doi: 10.1161/ATVBAHA.114.303724. Epub 2014 Aug 21.

23.

The platelet: life on the razor's edge between hemorrhage and thrombosis.

Coller BS.

Transfusion. 2014 Sep;54(9):2137-46. doi: 10.1111/trf.12806. Epub 2014 Aug 5. No abstract available.

24.

Association between shear stress and platelet-derived transforming growth factor-β1 release and activation in animal models of aortic valve stenosis.

Wang W, Vootukuri S, Meyer A, Ahamed J, Coller BS.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):1924-32. doi: 10.1161/ATVBAHA.114.303852. Epub 2014 Jun 5.

25.

Research participant-centered outcomes at NIH-supported clinical research centers.

Kost RG, Lee LN, Yessis JL, Wesley R, Alfano S, Alexander SR, Kassis SB, Cola P, Dozier A, Ford DE, Harris PA, Kim E, Lee SC, O'Riordan G, Roth MT, Schuff K, Wasser J, Henderson DK, Coller BS.

Clin Transl Sci. 2014 Dec;7(6):430-40. doi: 10.1111/cts.12167. Epub 2014 May 19.

26.

Talin-driven inside-out activation mechanism of platelet αIIbβ3 integrin probed by multimicrosecond, all-atom molecular dynamics simulations.

Provasi D, Negri A, Coller BS, Filizola M.

Proteins. 2014 Dec;82(12):3231-3240. doi: 10.1002/prot.24540. Epub 2014 Sep 25.

27.

A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor.

Jiang JK, McCoy JG, Shen M, LeClair CA, Huang W, Negri A, Li J, Blue R, Harrington AW, Naini S, David G 3rd, Choi WS, Volpi E, Fernandez J, Babayeva M, Nedelman MA, Filizola M, Coller BS, Thomas CJ.

Bioorg Med Chem Lett. 2014 Feb 15;24(4):1148-53. doi: 10.1016/j.bmcl.2013.12.122. Epub 2014 Jan 8.

28.

The Rockefeller University Navigation Program: a structured multidisciplinary protocol development and educational program to advance translational research.

Brassil D, Kost RG, Dowd KA, Hurley AM, Rainer TL, Coller BS.

Clin Transl Sci. 2014 Feb;7(1):12-9. doi: 10.1111/cts.12134. Epub 2014 Jan 9.

29.

Swing-out of the β3 hybrid domain is required for αIIbβ3 priming and normal cytoskeletal reorganization, but not adhesion to immobilized fibrinogen.

Cheng M, Li J, Negri A, Coller BS.

PLoS One. 2013 Dec 9;8(12):e81609. doi: 10.1371/journal.pone.0081609. eCollection 2013.

30.

Assessing participant-centered outcomes to improve clinical research.

Kost RG, Lee LM, Yessis J, Wesley RA, Henderson DK, Coller BS.

N Engl J Med. 2013 Dec 5;369(23):2179-81. doi: 10.1056/NEJMp1311461. No abstract available.

31.

Three-dimensional reconstruction of intact human integrin αIIbβ3: new implications for activation-dependent ligand binding.

Choi WS, Rice WJ, Stokes DL, Coller BS.

Blood. 2013 Dec 19;122(26):4165-71. doi: 10.1182/blood-2013-04-499194. Epub 2013 Oct 17.

32.

Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor β1 (TGF-β1) activation.

Brophy TM, Coller BS, Ahamed J.

J Biol Chem. 2013 Apr 12;288(15):10628-39. doi: 10.1074/jbc.M112.439034. Epub 2013 Mar 5.

33.

Development of a research participants' perception survey to improve clinical research.

Yessis JL, Kost RG, Lee LM, Coller BS, Henderson DK.

Clin Transl Sci. 2012 Dec;5(6):452-60. doi: 10.1111/j.1752-8062.2012.00443.x. Epub 2012 Oct 15.

34.

Translating from the rivers of Babylon to the coronary bloodstream.

Coller BS.

J Clin Invest. 2012 Nov;122(11):4293-9. doi: 10.1172/JCI66867. Epub 2012 Nov 1. No abstract available.

35.

Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group.

Fuster V, Bhatt DL, Califf RM, Michelson AD, Sabatine MS, Angiolillo DJ, Bates ER, Cohen DJ, Coller BS, Furie B, Hulot JS, Mann KG, Mega JL, Musunuru K, O'Donnell CJ, Price MJ, Schneider DJ, Simon DI, Weitz JI, Williams MS, Hoots WK, Rosenberg YD, Hasan AA.

Circulation. 2012 Sep 25;126(13):1645-62. No abstract available.

36.

Structure-based virtual screening of small-molecule antagonists of platelet integrin αIIbβ3 that do not prime the receptor to bind ligand.

Negri A, Li J, Naini S, Coller BS, Filizola M.

J Comput Aided Mol Des. 2012 Sep;26(9):1005-15. doi: 10.1007/s10822-012-9594-6. Epub 2012 Aug 15.

37.

Phenotyping bleeding.

James P, Coller BS.

Curr Opin Hematol. 2012 Sep;19(5):406-12. doi: 10.1097/MOH.0b013e32835673ab. Review.

38.

Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.

Zhu J, Choi WS, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D, Rasmussen M, Aster R, Thomas CJ, Filizola M, Springer TA, Coller BS.

Sci Transl Med. 2012 Mar 14;4(125):125ra32. doi: 10.1126/scitranslmed.3003576.

39.

Assessing research participants' perceptions of their clinical research experiences.

Kost RG, Lee LM, Yessis J, Coller BS, Henderson DK; Research Participant Perception Survey Focus Group Subcommittee.

Clin Transl Sci. 2011 Dec;4(6):403-13. doi: 10.1111/j.1752-8062.2011.00349.x. Epub 2011 Nov 7.

40.

Platelet TGF-β1 contributions to plasma TGF-β1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload.

Meyer A, Wang W, Qu J, Croft L, Degen JL, Coller BS, Ahamed J.

Blood. 2012 Jan 26;119(4):1064-74. doi: 10.1182/blood-2011-09-377648. Epub 2011 Dec 1.

41.

Historical perspective and future directions in platelet research.

Coller BS.

J Thromb Haemost. 2011 Jul;9 Suppl 1:374-95. doi: 10.1111/j.1538-7836.2011.04356.x. Review.

42.

Realigning incentives to achieve health care reform.

Coller BS.

JAMA. 2011 Jul 13;306(2):204-5. doi: 10.1001/jama.2011.978. No abstract available.

PMID:
21750300
43.

Impact of sex, age, race, ethnicity and aspirin use on bleeding symptoms in healthy adults.

Mauer AC, Khazanov NA, Levenkova N, Tian S, Barbour EM, Khalida C, Tobin JN, Coller BS.

J Thromb Haemost. 2011 Jan;9(1):100-8. doi: 10.1111/j.1538-7836.2010.04105.x.

44.

Closed headpiece of integrin αIIbβ3 and its complex with an αIIbβ3-specific antagonist that does not induce opening.

Zhu J, Zhu J, Negri A, Provasi D, Filizola M, Coller BS, Springer TA.

Blood. 2010 Dec 2;116(23):5050-9. doi: 10.1182/blood-2010-04-281154. Epub 2010 Aug 2.

45.

Creating an ontology-based human phenotyping system: The Rockefeller University bleeding history experience.

Mauer AC, Barbour EM, Khazanov NA, Levenkova N, Mollah SA, Coller BS.

Clin Transl Sci. 2009 Oct;2(5):382-5. doi: 10.1111/j.1752-8062.2009.00147.x.

46.

Traversing the valley of death: a guide to assessing prospects for translational success.

Coller BS, Califf RM.

Sci Transl Med. 2009 Dec 9;1(10):10cm9. doi: 10.1126/scitranslmed.3000265.

47.

Effects of limiting extension at the alphaIIb genu on ligand binding to integrin alphaIIbbeta3.

Blue R, Li J, Steinberger J, Murcia M, Filizola M, Coller BS.

J Biol Chem. 2010 Jun 4;285(23):17604-13. doi: 10.1074/jbc.M110.107763. Epub 2010 Apr 2.

48.

In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1.

Ahamed J, Janczak CA, Wittkowski KM, Coller BS.

PLoS One. 2009 Aug 12;4(8):e6608. doi: 10.1371/journal.pone.0006608.

49.

Targeted molecular dynamics reveals overall common conformational changes upon hybrid domain swing-out in beta3 integrins.

Provasi D, Murcia M, Coller BS, Filizola M.

Proteins. 2009 Nov 1;77(2):477-89. doi: 10.1002/prot.22463.

50.

Translational careers.

Andrews N, Burris JE, Cech TR, Coller BS, Crowley WF Jr, Gallin EK, Kelner KL, Kirch DG, Leshner AI, Morris CD, Nguyen FT, Oates J, Sung NS.

Science. 2009 May 15;324(5929):855. doi: 10.1126/science.1172137. No abstract available.

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