Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 20

1.

Lessons from the Established Status Epilepticus Treatment Trial.

Cock HR, Coles LD, Elm J, Silbergleit R, Chamberlain JM, Cloyd JC, Fountain N, Shinnar S, Lowenstein D, Conwit R, Bleck TP, Kapur J.

Epilepsy Behav. 2019 Oct 22:106296. doi: 10.1016/j.yebeh.2019.04.049. [Epub ahead of print]

PMID:
31653603
2.

Underdosing of Benzodiazepines in Patients With Status Epilepticus Enrolled in Established Status Epilepticus Treatment Trial.

Sathe AG, Tillman H, Coles LD, Elm JJ, Silbergleit R, Chamberlain J, Kapur J, Cock HR, Fountain NB, Shinnar S, Lowenstein DH, Conwit RA, Bleck TP, Cloyd JC.

Acad Emerg Med. 2019 Aug;26(8):940-943. doi: 10.1111/acem.13811. Epub 2019 Jul 18. No abstract available.

PMID:
31161706
3.

Intranasal Coadministration of a Diazepam Prodrug with a Converting Enzyme Results in Rapid Absorption of Diazepam in Rats.

Rautiola D, Maglalang PD, Cheryala N, Nelson KM, Georg GI, Fine JM, Svitak AL, Faltesek KA, Hanson LR, Mishra U, Coles LD, Cloyd JC, Siegel RA.

J Pharmacol Exp Ther. 2019 Sep;370(3):796-805. doi: 10.1124/jpet.118.255943. Epub 2019 Mar 5.

PMID:
30837282
4.

Rescue therapies for seizure emergencies: New modes of administration.

Maglalang PD, Rautiola D, Siegel RA, Fine JM, Hanson LR, Coles LD, Cloyd JC.

Epilepsia. 2018 Oct;59 Suppl 2:207-215. doi: 10.1111/epi.14479. Epub 2018 Aug 29.

5.

Repeated-Dose Oral N-Acetylcysteine in Parkinson's Disease: Pharmacokinetics and Effect on Brain Glutathione and Oxidative Stress.

Coles LD, Tuite PJ, Öz G, Mishra UR, Kartha RV, Sullivan KM, Cloyd JC, Terpstra M.

J Clin Pharmacol. 2018 Feb;58(2):158-167. doi: 10.1002/jcph.1008. Epub 2017 Sep 22.

6.

Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally Occurring Epilepsy.

Vuu I, Coles LD, Maglalang P, Leppik IE, Worrell G, Crepeau D, Mishra U, Cloyd JC, Patterson EE.

Front Vet Sci. 2016 Dec 5;3:107. eCollection 2016.

7.

A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics.

Schmitz NS, Krach LE, Coles LD, Mishra U, Agarwal SK, Cloyd JC, Kriel RL.

PM R. 2017 Aug;9(8):743-750. doi: 10.1016/j.pmrj.2016.11.002. Epub 2016 Nov 17.

PMID:
27867020
8.

Intravenous Administration of Stable-Labeled N-Acetylcysteine Demonstrates an Indirect Mechanism for Boosting Glutathione and Improving Redox Status.

Zhou J, Coles LD, Kartha RV, Nash N, Mishra U, Lund TC, Cloyd JC.

J Pharm Sci. 2015 Aug;104(8):2619-26. doi: 10.1002/jps.24482. Epub 2015 Jun 5.

PMID:
26052837
9.

Canine status epilepticus treated with fosphenytoin: A proof of principle study.

Patterson EE, Leppik IE, Coles LD, Podell M, Vite CH, Bush W, Cloyd JC.

Epilepsia. 2015 Jun;56(6):882-7. doi: 10.1111/epi.12994. Epub 2015 May 7.

10.

Use of IV fosphenytoin pharmacokinetics to determine the loading dose for a clinical trial of canine status epilepticus.

Coles LD, Leppik IE, Patterson EE, Rivers Z, Mishra U, Cloyd JC.

Epilepsia. 2015 Jun;56(6):888-94. doi: 10.1111/epi.12961. Epub 2015 May 7.

11.

A pilot study assessing pharmacokinetics and tolerability of oral and intravenous baclofen in healthy adult volunteers.

Agarwal SK, Kriel RL, Cloyd JC, Coles LD, Scherkenbach LA, Tobin MH, Krach LE.

J Child Neurol. 2015 Jan;30(1):37-41. doi: 10.1177/0883073814535504. Epub 2014 Jul 14.

PMID:
25028414
12.

Pharmacokinetics and pharmacodynamics of intravenous baclofen in dogs: a preliminary study.

Scherkenbach LA, Coles LD, Patterson EE, Cloyd JC, Krach LE, Kriel RL.

J Pharm Pharmacol. 2014 Jul;66(7):935-42. doi: 10.1111/jphp.12221. Epub 2014 Feb 13.

PMID:
24697865
13.

Feasibility study of a caregiver seizure alert system in canine epilepsy.

Coles LD, Patterson EE, Sheffield WD, Mavoori J, Higgins J, Michael B, Leyde K, Cloyd JC, Litt B, Vite C, Worrell GA.

Epilepsy Res. 2013 Oct;106(3):456-60. doi: 10.1016/j.eplepsyres.2013.06.007. Epub 2013 Aug 18.

14.

N-Acetylcysteine boosts brain and blood glutathione in Gaucher and Parkinson diseases.

Holmay MJ, Terpstra M, Coles LD, Mishra U, Ahlskog M, Öz G, Cloyd JC, Tuite PJ.

Clin Neuropharmacol. 2013 Jul-Aug;36(4):103-6. doi: 10.1097/WNF.0b013e31829ae713.

15.

Interaction of N-acetylcysteine and cysteine in human plasma.

Radtke KK, Coles LD, Mishra U, Orchard PJ, Holmay M, Cloyd JC.

J Pharm Sci. 2012 Dec;101(12):4653-9. doi: 10.1002/jps.23325. Epub 2012 Sep 27.

PMID:
23018672
16.

The role of academic institutions in the development of drugs for rare and neglected diseases.

Coles LD, Cloyd JC.

Clin Pharmacol Ther. 2012 Aug;92(2):193-202. doi: 10.1038/clpt.2012.83. Epub 2012 Jul 4. Review.

PMID:
22760003
17.

Canine status epilepticus: a translational platform for human therapeutic trials.

Leppik IE, Patterson EN, Coles LD, Craft EM, Cloyd JC.

Epilepsia. 2011 Oct;52 Suppl 8:31-4. doi: 10.1111/j.1528-1167.2011.03231.x.

18.

Clinical tolerance and toxicity of intravenous baclofen: a pilot study in a canine model.

Krach LE, Kriel RL, Patterson EE, Scherkenbach LA, Coles LD, Cloyd JC.

J Pediatr Rehabil Med. 2011;4(2):89-98. doi: 10.3233/PRM-2011-0160.

PMID:
21955965
19.

Estradiol and progesterone-mediated regulation of P-gp in P-gp overexpressing cells (NCI-ADR-RES) and placental cells (JAR).

Coles LD, Lee IJ, Voulalas PJ, Eddington ND.

Mol Pharm. 2009 Nov-Dec;6(6):1816-25. doi: 10.1021/mp900077q.

PMID:
19813763
20.

Distribution of saquinavir, methadone, and buprenorphine in maternal brain, placenta, and fetus during two different gestational stages of pregnancy in mice.

Coles LD, Lee IJ, Hassan HE, Eddington ND.

J Pharm Sci. 2009 Aug;98(8):2832-46. doi: 10.1002/jps.21644.

PMID:
19116954

Supplemental Content

Loading ...
Support Center