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Items: 22


Parkinson's disease-linked D620N VPS35 knockin mice manifest tau neuropathology and dopaminergic neurodegeneration.

Chen X, Kordich JK, Williams ET, Levine N, Cole-Strauss A, Marshall L, Labrie V, Ma J, Lipton JW, Moore DJ.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5765-5774. doi: 10.1073/pnas.1814909116. Epub 2019 Mar 6.


Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease.

Fischer DL, Auinger P, Goudreau JL, Paumier KL, Cole-Strauss A, Kemp CJ, Lipton JW, Sortwell CE.

Parkinsonism Relat Disord. 2018 Aug;53:70-75. doi: 10.1016/j.parkreldis.2018.05.003. Epub 2018 May 9.


Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression.

Fischer DL, Manfredsson FP, Kemp CJ, Cole-Strauss A, Lipton JW, Duffy MF, Polinski NK, Steece-Collier K, Collier TJ, Gombash SE, Buhlinger DJ, Sortwell CE.

Sci Rep. 2017 Nov 27;7(1):16356. doi: 10.1038/s41598-017-16690-x.


Subthalamic Nucleus Deep Brain Stimulation Employs trkB Signaling for Neuroprotection and Functional Restoration.

Fischer DL, Kemp CJ, Cole-Strauss A, Polinski NK, Paumier KL, Lipton JW, Steece-Collier K, Collier TJ, Buhlinger DJ, Sortwell CE.

J Neurosci. 2017 Jul 12;37(28):6786-6796. doi: 10.1523/JNEUROSCI.2060-16.2017. Epub 2017 Jun 12.


Sonic Hedgehog Controls the Phenotypic Fate and Therapeutic Efficacy of Grafted Neural Precursor Cells in a Model of Nigrostriatal Neurodegeneration.

Madhavan L, Daley BF, Davidson BL, Boudreau RL, Lipton JW, Cole-Strauss A, Steece-Collier K, Collier TJ.

PLoS One. 2015 Sep 4;10(9):e0137136. doi: 10.1371/journal.pone.0137136. eCollection 2015.


High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine.

Fischer DL, Collier TJ, Cole-Strauss A, Wohlgenant SL, Lipton JW, Steece-Collier K, Manfredsson FP, Kemp CJ, Sortwell CE.

PLoS One. 2015 Jul 29;10(7):e0133957. doi: 10.1371/journal.pone.0133957. eCollection 2015.


The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes.

Kanaan NM, Collier TJ, Cole-Strauss A, Grabinski T, Mattingly ZR, Winn ME, Steece-Collier K, Sortwell CE, Manfredsson FP, Lipton JW.

PLoS One. 2015 May 20;10(5):e0127768. doi: 10.1371/journal.pone.0127768. eCollection 2015.


Recombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain.

Polinski NK, Gombash SE, Manfredsson FP, Lipton JW, Kemp CJ, Cole-Strauss A, Kanaan NM, Steece-Collier K, Kuhn NC, Wohlgenant SL, Sortwell CE.

Neurobiol Aging. 2015 Feb;36(2):1110-20. doi: 10.1016/j.neurobiolaging.2014.07.047. Epub 2014 Oct 13.


Subthalamic nucleus stimulation increases brain derived neurotrophic factor in the nigrostriatal system and primary motor cortex.

Spieles-Engemann AL, Steece-Collier K, Behbehani MM, Collier TJ, Wohlgenant SL, Kemp CJ, Cole-Strauss A, Levine ND, Gombash SE, Thompson VB, Lipton JW, Sortwell CE.

J Parkinsons Dis. 2011;1(1):123-36.


Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model.

Gombash SE, Lipton JW, Collier TJ, Madhavan L, Steece-Collier K, Cole-Strauss A, Terpstra BT, Spieles-Engemann AL, Daley BF, Wohlgenant SL, Thompson VB, Manfredsson FP, Mandel RJ, Sortwell CE.

Mol Ther. 2012 Mar;20(3):544-54. doi: 10.1038/mt.2011.216. Epub 2011 Oct 18.


Atypical antipsychotic medications increase postprandial triglyceride and glucose levels in male rats: relationship with stearoyl-CoA desaturase activity.

McNamara RK, Jandacek R, Rider T, Tso P, Cole-Strauss A, Lipton JW.

Schizophr Res. 2011 Jun;129(1):66-73. doi: 10.1016/j.schres.2011.03.016. Epub 2011 Apr 7.


Differential effects of antipsychotic medications on polyunsaturated fatty acid biosynthesis in rats: Relationship with liver delta6-desaturase expression.

McNamara RK, Jandacek R, Rider T, Tso P, Cole-Strauss A, Lipton JW.

Schizophr Res. 2011 Jun;129(1):57-65. doi: 10.1016/j.schres.2011.03.006. Epub 2011 Mar 31.


Omega-3 fatty acid deficiency increases constitutive pro-inflammatory cytokine production in rats: relationship with central serotonin turnover.

McNamara RK, Jandacek R, Rider T, Tso P, Cole-Strauss A, Lipton JW.

Prostaglandins Leukot Essent Fatty Acids. 2010 Oct-Dec;83(4-6):185-91. doi: 10.1016/j.plefa.2010.08.004.


The role of calcium in hypoxia-induced signal transduction and gene expression.

Seta KA, Yuan Y, Spicer Z, Lu G, Bedard J, Ferguson TK, Pathrose P, Cole-Strauss A, Kaufhold A, Millhorn DE.

Cell Calcium. 2004 Sep-Oct;36(3-4):331-40. Review.


A plausible mechanism for gene correction by chimeric oligonucleotides.

Gamper HB Jr, Cole-Strauss A, Metz R, Parekh H, Kumar R, Kmiec EB.

Biochemistry. 2000 May 16;39(19):5808-16.


Targeted gene repair directed by the chimeric RNA/DNA oligonucleotide in a mammalian cell-free extract.

Cole-Strauss A, Gamper H, Holloman WK, Muñoz M, Cheng N, Kmiec EB.

Nucleic Acids Res. 1999 Mar 1;27(5):1323-30.


Targeted gene correction: a new strategy for molecular medicine.

Ye S, Cole-Strauss AC, Frank B, Kmiec EB.

Mol Med Today. 1998 Oct;4(10):431-7. Review.


Targeted gene conversion in a mammalian CD34+-enriched cell population using a chimeric RNA/DNA oligonucleotide.

Xiang Y, Cole-Strauss A, Yoon K, Gryn J, Kmiec EB.

J Mol Med (Berl). 1997 Nov-Dec;75(11-12):829-35.


Recombinational repair of genetic mutations.

Cole-Strauss A, Nöe A, Kmiec EB.

Antisense Nucleic Acid Drug Dev. 1997 Jun;7(3):211-6. Review. No abstract available.


Correction of the mutation responsible for sickle cell anemia by an RNA-DNA oligonucleotide.

Cole-Strauss A, Yoon K, Xiang Y, Byrne BC, Rice MC, Gryn J, Holloman WK, Kmiec EB.

Science. 1996 Sep 6;273(5280):1386-9.


Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide.

Yoon K, Cole-Strauss A, Kmiec EB.

Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2071-6.

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