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Items: 1 to 50 of 122

1.

The structural unit of melanin in the cell wall of the fungal pathogen Cryptococcus neoformans.

Camacho E, Vij R, Chrissian C, Prados-Rosales R, Gil D, O'Meally RN, Cordero RJB, Cole RN, McCaffery JM, Stark RE, Casadevall A.

J Biol Chem. 2019 Jul 5;294(27):10471-10489. doi: 10.1074/jbc.RA119.008684. Epub 2019 May 22.

PMID:
31118223
2.

Proteogenomic Annotation of Chinese Hamsters Reveals Extensive Novel Translation Events and Endogenous Retroviral Elements.

Li S, Cha SW, Heffner K, Hizal DB, Bowen MA, Chaerkady R, Cole RN, Tejwani V, Kaushik P, Henry M, Meleady P, Sharfstein ST, Betenbaugh MJ, Bafna V, Lewis NE.

J Proteome Res. 2019 Jun 7;18(6):2433-2445. doi: 10.1021/acs.jproteome.8b00935. Epub 2019 May 8.

PMID:
31020842
3.

Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening.

Steppan J, Wang H, Bergman Y, Rauer MJ, Tan S, Jandu S, Nandakumar K, Barreto-Ortiz S, Cole RN, Boronina TN, Zhu W, Halushka MK, An SS, Berkowitz DE, Santhanam L.

Am J Physiol Heart Circ Physiol. 2019 Jul 1;317(1):H49-H59. doi: 10.1152/ajpheart.00670.2018. Epub 2019 Apr 19.

PMID:
31002285
4.

Actomyosin contraction during cellularization is regulated in part by Src64 control of Actin 5C protein levels.

Carter TY, Gadwala S, Chougule AB, Bui APN, Sanders AC, Chaerkady R, Cormier N, Cole RN, Thomas JH.

Genesis. 2019 Jun;57(6):e23297. doi: 10.1002/dvg.23297. Epub 2019 Apr 11.

PMID:
30974046
5.

A methodology for discovering novel brain-relevant peptides: Combination of ribosome profiling and peptidomics.

Tharakan R, Kreimer S, Ubaida-Mohien C, Lavoie J, Olexiouk V, Menschaert G, Ingolia NT, Cole RN, Ishizuka K, Sawa A, Nucifora LG.

Neurosci Res. 2019 Mar 9. pii: S0168-0102(18)30722-3. doi: 10.1016/j.neures.2019.02.006. [Epub ahead of print]

PMID:
30862443
6.

The nonlesional skin surface distinguishes atopic dermatitis with food allergy as a unique endotype.

Leung DYM, Calatroni A, Zaramela LS, LeBeau PK, Dyjack N, Brar K, David G, Johnson K, Leung S, Ramirez-Gama M, Liang B, Rios C, Montgomery MT, Richers BN, Hall CF, Norquest KA, Jung J, Bronova I, Kreimer S, Talbot CC Jr, Crumrine D, Cole RN, Elias P, Zengler K, Seibold MA, Berdyshev E, Goleva E.

Sci Transl Med. 2019 Feb 20;11(480). pii: eaav2685. doi: 10.1126/scitranslmed.aav2685.

PMID:
30787169
7.

Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal.

Lee SE, Schulze K, Stewart CP, Cole RN, Wu LS, Eroglu A, Yager JD, Groopman J, Christian P, West KP Jr.

J Lipid Res. 2019 Jan;60(1):149-160. doi: 10.1194/jlr.P088542. Epub 2018 Nov 25.

8.

Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation.

Liu X, Abraham JM, Cheng Y, Wang Z, Wang Z, Zhang G, Ashktorab H, Smoot DT, Cole RN, Boronina TN, DeVine LR, Talbot CC Jr, Liu Z, Meltzer SJ.

Mol Ther Nucleic Acids. 2018 Dec 7;13:312-321. doi: 10.1016/j.omtn.2018.09.010. Epub 2018 Sep 22.

9.

The prionlike domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization.

Rhoads SN, Monahan ZT, Yee DS, Leung AY, Newcombe CG, O'Meally RN, Cole RN, Shewmaker FP.

Mol Biol Cell. 2018 Aug 1;29(15):1786-1797. doi: 10.1091/mbc.E17-12-0735. Epub 2018 Jun 13.

10.

Novel Plasma Proteins in Nepalese School-aged Children are Associated with a Small Head Size at Birth.

Lee SE, West KP Jr, Cole RN, Schulze KJ, Wu LS, Yager JD, Groopman J, Christian P.

Sci Rep. 2018 Apr 23;8(1):6390. doi: 10.1038/s41598-018-24640-4.

11.

Global Effects of DDX3 Inhibition on Cell Cycle Regulation Identified by a Combined Phosphoproteomics and Single Cell Tracking Approach.

Heerma van Voss MR, Kammers K, Vesuna F, Brilliant J, Bergman Y, Tantravedi S, Wu X, Cole RN, Holland A, van Diest PJ, Raman V.

Transl Oncol. 2018 Jun;11(3):755-763. doi: 10.1016/j.tranon.2018.04.001. Epub 2018 Apr 24.

12.

Plasma proteins associated with circulating carotenoids in Nepalese school-aged children.

Eroglu A, Schulze KJ, Yager J, Cole RN, Christian P, Nonyane BAS, Lee SE, Wu LSF, Khatry S, Groopman J, West KP Jr.

Arch Biochem Biophys. 2018 May 15;646:153-160. doi: 10.1016/j.abb.2018.03.025. Epub 2018 Mar 30.

13.

Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.

Monahan Z, Ryan VH, Janke AM, Burke KA, Rhoads SN, Zerze GH, O'Meally R, Dignon GL, Conicella AE, Zheng W, Best RB, Cole RN, Mittal J, Shewmaker F, Fawzi NL.

EMBO J. 2017 Oct 16;36(20):2951-2967. doi: 10.15252/embj.201696394. Epub 2017 Aug 8.

14.

Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition.

Maheshwari S, Miller MS, O'Meally R, Cole RN, Amzel LM, Gabelli SB.

J Biol Chem. 2017 Aug 18;292(33):13541-13550. doi: 10.1074/jbc.M116.772426. Epub 2017 Jul 4.

15.

Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats.

Ratovitski T, O'Meally RN, Jiang M, Chaerkady R, Chighladze E, Stewart JC, Wang X, Arbez N, Roby E, Alexandris A, Duan W, Vijayvargia R, Seong IS, Lavery DJ, Cole RN, Ross CA.

J Proteome Res. 2017 Aug 4;16(8):2692-2708. doi: 10.1021/acs.jproteome.6b00991. Epub 2017 Jul 3.

16.

Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing.

Kim A, Boronina TN, Cole RN, Darrah E, Sadegh-Nasseri S.

Sci Rep. 2017 Apr 19;7:46418. doi: 10.1038/srep46418.

17.

Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.

Dickens AM, Tovar-Y-Romo LB, Yoo SW, Trout AL, Bae M, Kanmogne M, Megra B, Williams DW, Witwer KW, Gacias M, Tabatadze N, Cole RN, Casaccia P, Berman JW, Anthony DC, Haughey NJ.

Sci Signal. 2017 Apr 4;10(473). pii: eaai7696. doi: 10.1126/scisignal.aai7696.

18.

Fatty acid synthase inhibits the O-GlcNAcase during oxidative stress.

Groves JA, Maduka AO, O'Meally RN, Cole RN, Zachara NE.

J Biol Chem. 2017 Apr 21;292(16):6493-6511. doi: 10.1074/jbc.M116.760785. Epub 2017 Feb 23.

19.

The Plasma Proteome Is Associated with Anthropometric Status of Undernourished Nepalese School-Aged Children.

Lee SE, Stewart CP, Schulze KJ, Cole RN, Wu LS, Yager JD, Groopman JD, Khatry SK, Adhikari RK, Christian P, West KP Jr.

J Nutr. 2017 Mar;147(3):304-313. doi: 10.3945/jn.116.243014. Epub 2017 Feb 1.

20.

Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis.

Darrah E, Kim A, Zhang X, Boronina T, Cole RN, Fava A, Giles JT, Bingham III CO, Chalmers MJ, Griffin PR, Sadegh-Nasseri S, Rosen A.

J Proteome Res. 2017 Jan 6;16(1):355-365. doi: 10.1021/acs.jproteome.6b00617. Epub 2016 Oct 20.

21.

Combined Antibody/Lectin Enrichment Identifies Extensive Changes in the O-GlcNAc Sub-proteome upon Oxidative Stress.

Lee A, Miller D, Henry R, Paruchuri VD, O'Meally RN, Boronina T, Cole RN, Zachara NE.

J Proteome Res. 2016 Dec 2;15(12):4318-4336. Epub 2016 Oct 14.

PMID:
27669760
22.

Quantitative Proteomic Analysis Reveals Similarities between Huntington's Disease (HD) and Huntington's Disease-Like 2 (HDL2) Human Brains.

Ratovitski T, Chaerkady R, Kammers K, Stewart JC, Zavala A, Pletnikova O, Troncoso JC, Rudnicki DD, Margolis RL, Cole RN, Ross CA.

J Proteome Res. 2016 Sep 2;15(9):3266-83. doi: 10.1021/acs.jproteome.6b00448. Epub 2016 Aug 3.

23.

Integrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death.

Foster DB, Liu T, Kammers K, O'Meally R, Yang N, Papanicolaou KN, Talbot CC Jr, Cole RN, O'Rourke B.

J Proteome Res. 2016 Sep 2;15(9):3009-28. doi: 10.1021/acs.jproteome.6b00149. Epub 2016 Aug 3.

24.

Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1.

Bullen JW, Tchernyshyov I, Holewinski RJ, DeVine L, Wu F, Venkatraman V, Kass DL, Cole RN, Van Eyk J, Semenza GL.

Sci Signal. 2016 May 31;9(430):ra56. doi: 10.1126/scisignal.aaf0583.

25.

FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1.

Khan SY, Vasanth S, Kabir F, Gottsch JD, Khan AO, Chaerkady R, Lee MC, Leitch CC, Ma Z, Laux J, Villasmil R, Khan SN, Riazuddin S, Akram J, Cole RN, Talbot CC, Pourmand N, Zaghloul NA, Hejtmancik JF, Riazuddin SA.

Nat Commun. 2016 Apr 6;7:10953. doi: 10.1038/ncomms10953.

26.

Plasma Selenium Protein P Isoform 1 (SEPP1): A Predictor of Selenium Status in Nepalese Children Detected by Plasma Proteomics.

Schulze KJ, Cole RN, Chaerkady R, Wu LSF, Nonyane BAS, Lee SE, Yager JD, Groopman JD, Christian P, West KP Jr.

Int J Vitam Nutr Res. 2017 Sep;87(5-6):1-10. doi: 10.1024/0300-9831/a000256. Epub 2016 May 10.

PMID:
27164173
27.

General intelligence is associated with subclinical inflammation in Nepalese children: A population-based plasma proteomics study.

Lee SE, West KP Jr, Cole RN, Schulze KJ, Wu LS, Yager JD, Groopman J, Christian P.

Brain Behav Immun. 2016 Aug;56:253-63. doi: 10.1016/j.bbi.2016.03.023. Epub 2016 Mar 30.

28.

Biological Systems of Vitamin K: A Plasma Nutriproteomics Study of Subclinical Vitamin K Deficiency in 500 Nepalese Children.

Lee SE, Schulze KJ, Cole RN, Wu LS, Yager JD, Groopman J, Christian P, West KP Jr.

OMICS. 2016 Apr;20(4):214-23. doi: 10.1089/omi.2015.0178. Epub 2016 Feb 25.

29.

PRINT: A Protein Bioconjugation Method with Exquisite N-terminal Specificity.

Sur S, Qiao Y, Fries A, O'Meally RN, Cole RN, Kinzler KW, Vogelstein B, Zhou S.

Sci Rep. 2015 Dec 17;5:18363. doi: 10.1038/srep18363.

30.

Plasma Proteome Biomarkers of Inflammation in School Aged Children in Nepal.

Lee SE, West KP Jr, Cole RN, Schulze KJ, Christian P, Wu LS, Yager JD, Groopman J, Ruczinski I.

PLoS One. 2015 Dec 4;10(12):e0144279. doi: 10.1371/journal.pone.0144279. eCollection 2015.

31.

Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation.

Dong Q, Giorgianni F, Beranova-Giorgianni S, Deng X, O'Meally RN, Bridges D, Park EA, Cole RN, Elam MB, Raghow R.

Biosci Rep. 2015 Nov 20;36(1):e00284. doi: 10.1042/BSR20150234.

32.

A Plasma α-Tocopherome Can Be Identified from Proteins Associated with Vitamin E Status in School-Aged Children of Nepal.

West KP Jr, Cole RN, Shrestha S, Schulze KJ, Lee SE, Betz J, Nonyane BA, Wu LS, Yager JD, Groopman JD, Christian P.

J Nutr. 2015 Dec;145(12):2646-56. doi: 10.3945/jn.115.210682. Epub 2015 Oct 7.

33.

Elucidation of the CHO Super-Ome (CHO-SO) by Proteoinformatics.

Kumar A, Baycin-Hizal D, Wolozny D, Pedersen LE, Lewis NE, Heffner K, Chaerkady R, Cole RN, Shiloach J, Zhang H, Bowen MA, Betenbaugh MJ.

J Proteome Res. 2015 Nov 6;14(11):4687-703. doi: 10.1021/acs.jproteome.5b00588. Epub 2015 Oct 13.

34.

RNA helicase DDX3: a novel therapeutic target in Ewing sarcoma.

Wilky BA, Kim C, McCarty G, Montgomery EA, Kammers K, DeVine LR, Cole RN, Raman V, Loeb DM.

Oncogene. 2016 May 19;35(20):2574-83. doi: 10.1038/onc.2015.336. Epub 2015 Sep 14.

PMID:
26364611
35.

Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection.

Chung HS, Murray CI, Venkatraman V, Crowgey EL, Rainer PP, Cole RN, Bomgarden RD, Rogers JC, Balkan W, Hare JM, Kass DA, Van Eyk JE.

Circ Res. 2015 Oct 23;117(10):846-57. doi: 10.1161/CIRCRESAHA.115.307336. Epub 2015 Sep 3.

36.

Proteins with Intrinsically Disordered Domains Are Preferentially Recruited to Polyglutamine Aggregates.

Wear MP, Kryndushkin D, O'Meally R, Sonnenberg JL, Cole RN, Shewmaker FP.

PLoS One. 2015 Aug 28;10(8):e0136362. doi: 10.1371/journal.pone.0136362. eCollection 2015.

37.

Removal of Abnormal Myofilament O-GlcNAcylation Restores Ca2+ Sensitivity in Diabetic Cardiac Muscle.

Ramirez-Correa GA, Ma J, Slawson C, Zeidan Q, Lugo-Fagundo NS, Xu M, Shen X, Gao WD, Caceres V, Chakir K, DeVine L, Cole RN, Marchionni L, Paolocci N, Hart GW, Murphy AM.

Diabetes. 2015 Oct;64(10):3573-87. doi: 10.2337/db14-1107. Epub 2015 Jun 24.

38.

Detecting Significant Changes in Protein Abundance.

Kammers K, Cole RN, Tiengwe C, Ruczinski I.

EuPA Open Proteom. 2015 Jun;7:11-19.

39.

Occurrence of a multimeric high-molecular-weight glyceraldehyde-3-phosphate dehydrogenase in human serum.

Kunjithapatham R, Geschwind JF, Devine L, Boronina TN, O'Meally RN, Cole RN, Torbenson MS, Ganapathy-Kanniappan S.

J Proteome Res. 2015 Apr 3;14(4):1645-56. doi: 10.1021/acs.jproteome.5b00089. Epub 2015 Mar 18.

40.

Communication between the N and C termini is required for copper-stimulated Ser/Thr phosphorylation of Cu(I)-ATPase (ATP7B).

Braiterman LT, Gupta A, Chaerkady R, Cole RN, Hubbard AL.

J Biol Chem. 2015 Apr 3;290(14):8803-19. doi: 10.1074/jbc.M114.627414. Epub 2015 Feb 9.

41.

Assessing Amide Proton Transfer (APT) MRI Contrast Origins in 9 L Gliosarcoma in the Rat Brain Using Proteomic Analysis.

Yan K, Fu Z, Yang C, Zhang K, Jiang S, Lee DH, Heo HY, Zhang Y, Cole RN, Van Eyk JE, Zhou J.

Mol Imaging Biol. 2015 Aug;17(4):479-87. doi: 10.1007/s11307-015-0828-6.

42.

Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources.

Kim A, Hartman IZ, Poore B, Boronina T, Cole RN, Song N, Ciudad MT, Caspi RR, Jaraquemada D, Sadegh-Nasseri S.

Nat Commun. 2014 Nov 21;5:5369. doi: 10.1038/ncomms6369.

43.

Quantitative phosphoproteomics reveals crosstalk between phosphorylation and O-GlcNAc in the DNA damage response pathway.

Zhong J, Martinez M, Sengupta S, Lee A, Wu X, Chaerkady R, Chatterjee A, O'Meally RN, Cole RN, Pandey A, Zachara NE.

Proteomics. 2015 Jan;15(2-3):591-607. doi: 10.1002/pmic.201400339.

44.

Ganglioside regulation of AMPA receptor trafficking.

Prendergast J, Umanah GK, Yoo SW, Lagerlöf O, Motari MG, Cole RN, Huganir RL, Dawson TM, Dawson VL, Schnaar RL.

J Neurosci. 2014 Sep 24;34(39):13246-58. doi: 10.1523/JNEUROSCI.1149-14.2014.

45.

PHD3-mediated prolyl hydroxylation of nonmuscle actin impairs polymerization and cell motility.

Luo W, Lin B, Wang Y, Zhong J, O'Meally R, Cole RN, Pandey A, Levchenko A, Semenza GL.

Mol Biol Cell. 2014 Sep 15;25(18):2788-96. doi: 10.1091/mbc.E14-02-0775. Epub 2014 Jul 30.

46.

Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK).

Cao J, Meng S, Chang E, Beckwith-Fickas K, Xiong L, Cole RN, Radovick S, Wondisford FE, He L.

J Biol Chem. 2014 Jul 25;289(30):20435-46.

47.

OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase.

Pandey D, Bhunia A, Oh YJ, Chang F, Bergman Y, Kim JH, Serbo J, Boronina TN, Cole RN, Van Eyk J, Remaley AT, Berkowitz DE, Romer LH.

Circ Res. 2014 Aug 1;115(4):450-9. doi: 10.1161/CIRCRESAHA.115.304262. Epub 2014 Jun 5.

PMID:
24903103
48.

Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.

Watkin EE, Arbez N, Waldron-Roby E, O'Meally R, Ratovitski T, Cole RN, Ross CA.

PLoS One. 2014 Feb 5;9(2):e88284. doi: 10.1371/journal.pone.0088284. eCollection 2014.

49.

Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation.

Zhang Y, Dayalan Naidu S, Samarasinghe K, Van Hecke GC, Pheely A, Boronina TN, Cole RN, Benjamin IJ, Cole PA, Ahn YH, Dinkova-Kostova AT.

Br J Cancer. 2014 Jan 7;110(1):71-82. doi: 10.1038/bjc.2013.710. Epub 2013 Dec 5.

50.

The plasma proteome identifies expected and novel proteins correlated with micronutrient status in undernourished Nepalese children.

Cole RN, Ruczinski I, Schulze K, Christian P, Herbrich S, Wu L, Devine LR, O'Meally RN, Shrestha S, Boronina TN, Yager JD, Groopman J, West KP Jr.

J Nutr. 2013 Oct;143(10):1540-8. doi: 10.3945/jn.113.175018. Epub 2013 Aug 21.

PMID:
23966331

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