Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 110


Glucan-Chitin Particles Enhance Th17 Response and Improve Protective Efficacy of a Multivalent Antigen (rCpa1) against Pulmonary Coccidioides posadasii Infection.

Hung CY, Zhang H, Castro-Lopez N, Ostroff GR, Khoshlenar P, Abraham A, Cole GT, Negron A, Forsthuber T, Peng T, Galgiani JN, Ampel NM, Yu JJ.

Infect Immun. 2018 Oct 25;86(11). pii: e00070-18. doi: 10.1128/IAI.00070-18. Print 2018 Nov.


Preclinical identification of vaccine induced protective correlates in human leukocyte antigen expressing transgenic mice infected with Coccidioides posadasii.

Hurtgen BJ, Castro-Lopez N, Jiménez-Alzate MDP, Cole GT, Hung CY.

Vaccine. 2016 Oct 17;34(44):5336-5343. doi: 10.1016/j.vaccine.2016.08.078. Epub 2016 Sep 9.


Flow Cytometric Analysis of Protective T-Cell Response Against Pulmonary Coccidioides Infection.

Hung CY, Wozniak KL, Cole GT.

Methods Mol Biol. 2016;1403:551-66. doi: 10.1007/978-1-4939-3387-7_31.


Card9- and MyD88-Mediated Gamma Interferon and Nitric Oxide Production Is Essential for Resistance to Subcutaneous Coccidioides posadasii Infection.

Hung CY, Castro-Lopez N, Cole GT.

Infect Immun. 2016 Mar 24;84(4):1166-75. doi: 10.1128/IAI.01066-15. Print 2016 Apr.


Interleukin-1 receptor but not Toll-like receptor 2 is essential for MyD88-dependent Th17 immunity to Coccidioides infection.

Hung CY, Jiménez-Alzate Mdel P, Gonzalez A, Wüthrich M, Klein BS, Cole GT.

Infect Immun. 2014 May;82(5):2106-14. doi: 10.1128/IAI.01579-13. Epub 2014 Mar 10.


Vaccinated C57BL/6 mice develop protective and memory T cell responses to Coccidioides posadasii infection in the absence of interleukin-10.

Hung CY, Castro-Lopez N, Cole GT.

Infect Immun. 2014 Feb;82(2):903-13. doi: 10.1128/IAI.01148-13. Epub 2013 Dec 9.


C-type lectin receptors differentially induce th17 cells and vaccine immunity to the endemic mycosis of North America.

Wang H, LeBert V, Hung CY, Galles K, Saijo S, Lin X, Cole GT, Klein BS, Wüthrich M.

J Immunol. 2014 Feb 1;192(3):1107-1119. doi: 10.4049/jimmunol.1302314. Epub 2014 Jan 3.


Novel strategies to enhance vaccine immunity against coccidioidomycosis.

Cole GT, Hung CY, Sanderson SD, Hurtgen BJ, Wüthrich M, Klein BS, Deepe GS, Ostroff GR, Levitz SM.

PLoS Pathog. 2013;9(12):e1003768. doi: 10.1371/journal.ppat.1003768. Epub 2013 Dec 19. No abstract available.


Progress Toward a Human Vaccine Against Coccidioidomycosis.

Cole GT, Hurtgen BJ, Hung CY.

Curr Fungal Infect Rep. 2012 Dec 1;6(4):235-244.


Extracellular ammonia at sites of pulmonary infection with Coccidioides posadasii contributes to severity of the respiratory disease.

Wise HZ, Hung CY, Whiston E, Taylor JW, Cole GT.

Microb Pathog. 2013 Jun-Jul;59-60:19-28. doi: 10.1016/j.micpath.2013.04.003. Epub 2013 Apr 10.


Construction and evaluation of a novel recombinant T cell epitope-based vaccine against Coccidioidomycosis.

Hurtgen BJ, Hung CY, Ostroff GR, Levitz SM, Cole GT.

Infect Immun. 2012 Nov;80(11):3960-74. doi: 10.1128/IAI.00566-12. Epub 2012 Sep 4.


Comparative transcriptomics of the saprobic and parasitic growth phases in Coccidioides spp.

Whiston E, Zhang Wise H, Sharpton TJ, Jui G, Cole GT, Taylor JW.

PLoS One. 2012;7(7):e41034. doi: 10.1371/journal.pone.0041034. Epub 2012 Jul 20.


Transactivation of inducible nitric oxide synthase gene by Kruppel-like factor 6 regulates apoptosis during influenza A virus infection.

Mgbemena V, Segovia JA, Chang TH, Tsai SY, Cole GT, Hung CY, Bose S.

J Immunol. 2012 Jul 15;189(2):606-15. doi: 10.4049/jimmunol.1102742. Epub 2012 Jun 18.


An agonist of human complement fragment C5a enhances vaccine immunity against Coccidioides infection.

Hung CY, Hurtgen BJ, Bellecourt M, Sanderson SD, Morgan EL, Cole GT.

Vaccine. 2012 Jun 29;30(31):4681-90. doi: 10.1016/j.vaccine.2012.04.084. Epub 2012 May 8.


Gene disruption in Coccidioides using hygromycin or phleomycin resistance markers.

Hung CY, Wise HZ, Cole GT.

Methods Mol Biol. 2012;845:131-47. doi: 10.1007/978-1-61779-539-8_9.


Biofilm and planktonic pneumococci demonstrate disparate immunoreactivity to human convalescent sera.

Sanchez CJ, Hurtgen BJ, Lizcano A, Shivshankar P, Cole GT, Orihuela CJ.

BMC Microbiol. 2011 Nov 2;11:245. doi: 10.1186/1471-2180-11-245.


Absence of phagocyte NADPH oxidase 2 leads to severe inflammatory response in lungs of mice infected with Coccidioides.

Gonzalez A, Hung CY, Cole GT.

Microb Pathog. 2011 Dec;51(6):432-41. doi: 10.1016/j.micpath.2011.08.003. Epub 2011 Aug 29.


Vaccine immunity to coccidioidomycosis occurs by early activation of three signal pathways of T helper cell response (Th1, Th2, and Th17).

Hung CY, Gonzalez A, Wüthrich M, Klein BS, Cole GT.

Infect Immun. 2011 Nov;79(11):4511-22. doi: 10.1128/IAI.05726-11. Epub 2011 Aug 22.


A TCR transgenic mouse reactive with multiple systemic dimorphic fungi.

Wüthrich M, Hung CY, Gern BH, Pick-Jacobs JC, Galles KJ, Filutowicz HI, Cole GT, Klein BS.

J Immunol. 2011 Aug 1;187(3):1421-31. doi: 10.4049/jimmunol.1100921. Epub 2011 Jun 24.


Nitric oxide synthase activity has limited influence on the control of Coccidioides infection in mice.

Gonzalez A, Hung CY, Cole GT.

Microb Pathog. 2011 Sep;51(3):161-8. doi: 10.1016/j.micpath.2011.03.013. Epub 2011 Apr 14.


Basic Biology of Fungi.

Cole GT.

In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 73.


Coccidioides releases a soluble factor that suppresses nitric oxide production by murine primary macrophages.

Gonzalez A, Hung CY, Cole GT.

Microb Pathog. 2011 Feb;50(2):100-8. doi: 10.1016/j.micpath.2010.11.006. Epub 2010 Dec 1.


Population genomic sequencing of Coccidioides fungi reveals recent hybridization and transposon control.

Neafsey DE, Barker BM, Sharpton TJ, Stajich JE, Park DJ, Whiston E, Hung CY, McMahan C, White J, Sykes S, Heiman D, Young S, Zeng Q, Abouelleil A, Aftuck L, Bessette D, Brown A, FitzGerald M, Lui A, Macdonald JP, Priest M, Orbach MJ, Galgiani JN, Kirkland TN, Cole GT, Birren BW, Henn MR, Taylor JW, Rounsley SD.

Genome Res. 2010 Jul;20(7):938-46. doi: 10.1101/gr.103911.109. Epub 2010 Jun 1.


Single-step conjugation of bioactive peptides to proteins via a self-contained succinimidyl bis-arylhydrazone.

Phillips JA, Morgan EL, Dong Y, Cole GT, McMahan C, Hung CY, Sanderson SD.

Bioconjug Chem. 2009 Oct 21;20(10):1950-7. doi: 10.1021/bc9002794. Epub 2009 Sep 29.


Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives.

Sharpton TJ, Stajich JE, Rounsley SD, Gardner MJ, Wortman JR, Jordar VS, Maiti R, Kodira CD, Neafsey DE, Zeng Q, Hung CY, McMahan C, Muszewska A, Grynberg M, Mandel MA, Kellner EM, Barker BM, Galgiani JN, Orbach MJ, Kirkland TN, Cole GT, Henn MR, Birren BW, Taylor JW.

Genome Res. 2009 Oct;19(10):1722-31. doi: 10.1101/gr.087551.108. Epub 2009 Aug 28.


A genetically engineered live attenuated vaccine of Coccidioides posadasii protects BALB/c mice against coccidioidomycosis.

Xue J, Chen X, Selby D, Hung CY, Yu JJ, Cole GT.

Infect Immun. 2009 Aug;77(8):3196-208. doi: 10.1128/IAI.00459-09. Epub 2009 Jun 1.


Virulence mechanisms of coccidioides.

Hung CY, Xue J, Cole GT.

Ann N Y Acad Sci. 2007 Sep;1111:225-35. Epub 2007 May 18. Review.


Evolution of the mating type locus: insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii.

Fraser JA, Stajich JE, Tarcha EJ, Cole GT, Inglis DO, Sil A, Heitman J.

Eukaryot Cell. 2007 Apr;6(4):622-9. Epub 2007 Mar 2.


Lower filamentation rates of Candida dubliniensis contribute to its lower virulence in comparison with Candida albicans.

Stokes C, Moran GP, Spiering MJ, Cole GT, Coleman DC, Sullivan DJ.

Fungal Genet Biol. 2007 Sep;44(9):920-31. Epub 2007 Jan 23.


Coccidioides posadasii produces melanin in vitro and during infection.

Nosanchuk JD, Yu JJ, Hung CY, Casadevall A, Cole GT.

Fungal Genet Biol. 2007 Jun;44(6):517-20. Epub 2006 Oct 30.


Multivalent recombinant protein vaccine against coccidioidomycosis.

Tarcha EJ, Basrur V, Hung CY, Gardner MJ, Cole GT.

Infect Immun. 2006 Oct;74(10):5802-13.


Improved protection of mice against lethal respiratory infection with Coccidioides posadasii using two recombinant antigens expressed as a single protein.

Shubitz LF, Yu JJ, Hung CY, Kirkland TN, Peng T, Perrill R, Simons J, Xue J, Herr RA, Cole GT, Galgiani JN.

Vaccine. 2006 Jul 26;24(31-32):5904-11. Epub 2006 Apr 18.


Phase-specific gene expression underlying morphological adaptations of the dimorphic human pathogenic fungus, Coccidioides posadasii.

Johannesson H, Kasuga T, Schaller RA, Good B, Gardner MJ, Townsend JP, Cole GT, Taylor JW.

Fungal Genet Biol. 2006 Aug;43(8):545-59. Epub 2006 May 12.


Urease produced by Coccidioides posadasii contributes to the virulence of this respiratory pathogen.

Mirbod-Donovan F, Schaller R, Hung CY, Xue J, Reichard U, Cole GT.

Infect Immun. 2006 Jan;74(1):504-15.


Characterization of a serodiagnostic complement fixation antigen of Coccidioides posadasii expressed in the nonpathogenic Fungus Uncinocarpus reesii.

Yu JJ, Kirkland TN, Hall LK, Wopschall J, Smith RC, Hung CY, Chen X, Tarcha E, Thomas PW, Cole GT.

J Clin Microbiol. 2005 Nov;43(11):5462-9.


A metalloproteinase of Coccidioides posadasii contributes to evasion of host detection.

Hung CY, Seshan KR, Yu JJ, Schaller R, Xue J, Basrur V, Gardner MJ, Cole GT.

Infect Immun. 2005 Oct;73(10):6689-703.


Immune response of vaccinated and non-vaccinated mice to Coccidioides posadasii infection.

Xue J, Hung CY, Yu JJ, Cole GT.

Vaccine. 2005 May 20;23(27):3535-44.


A vaccine against coccidioidomycosis is justified and attainable.

Cole GT, Xue JM, Okeke CN, Tarcha EJ, Basrur V, Schaller RA, Herr RA, Yu JJ, Hung CY.

Med Mycol. 2004 Jun;42(3):189-216. Review.


Positive directional selection in the proline-rich antigen (PRA) gene among the human pathogenic fungi Coccidioides immitis, C. posadasii and their closest relatives.

Johannesson H, Vidal P, Guarro J, Herr RA, Cole GT, Taylor JW.

Mol Biol Evol. 2004 Jun;21(6):1134-45. Epub 2004 Mar 19.


Profiling gene expression in Coccidioides posadasii.

Delgado N, Hung CY, Tarcha E, Gardner MJ, Cole GT.

Med Mycol. 2004 Feb;42(1):59-71.


Purification and characterization of urease isolated from the pathogenic fungus Coccidioides immitis.

Mirbod F, Schaller RA, Cole GT.

Med Mycol. 2002 Feb;40(1):35-44.


The parasitic cell wall of Coccidioides immitis.

Cole GT, Hung CY.

Med Mycol. 2001;39 Suppl 1:31-40. Review.


Reintroduction of the PLB1 gene into Candida albicans restores virulence in vivo.

Mukherjee PK, Seshan KR, Leidich SD, Chandra J, Cole GT, Ghannoum MA.

Microbiology. 2001 Sep;147(Pt 9):2585-97.


Supplemental Content

Support Center