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Items: 24

1.

Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan.

Xie J, de Souza Alves V, von der Haar T, O'Keefe L, Lenchine RV, Jensen KB, Liu R, Coldwell MJ, Wang X, Proud CG.

Curr Biol. 2019 Mar 4;29(5):737-749.e5. doi: 10.1016/j.cub.2019.01.029. Epub 2019 Feb 14.

PMID:
30773367
2.

PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells.

Yeomans A, Lemm E, Wilmore S, Cavell BE, Valle-Argos B, Krysov S, Hidalgo MS, Leonard E, Willis AE, Forconi F, Stevenson FK, Steele AJ, Coldwell MJ, Packham G.

Oncotarget. 2016 Nov 15;7(46):74807-74819. doi: 10.18632/oncotarget.11655.

3.

Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits.

Wortham NC, Stewart JD, Harris S, Coldwell MJ, Proud CG.

Biochem J. 2016 Mar 1;473(5):571-80. doi: 10.1042/BJ20150828. Epub 2015 Nov 27.

PMID:
26614765
4.

Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation.

Yeomans A, Thirdborough SM, Valle-Argos B, Linley A, Krysov S, Hidalgo MS, Leonard E, Ishfaq M, Wagner SD, Willis AE, Steele AJ, Stevenson FK, Forconi F, Coldwell MJ, Packham G.

Blood. 2016 Jan 28;127(4):449-57. doi: 10.1182/blood-2015-07-660969. Epub 2015 Oct 21.

PMID:
26491071
5.

G-quadruplexes mediate local translation in neurons.

Schofield JP, Cowan JL, Coldwell MJ.

Biochem Soc Trans. 2015 Jun;43(3):338-42. doi: 10.1042/BST20150053. Review.

PMID:
26009173
6.

ABC50 mutants modify translation start codon selection.

Stewart JD, Cowan JL, Perry LS, Coldwell MJ, Proud CG.

Biochem J. 2015 Apr 15;467(2):217-29. doi: 10.1042/BJ20141453.

PMID:
25597744
7.

mTORCing about myogenic differentiation.

Iadevaia V, Cowan JL, Coldwell MJ.

Cell Cycle. 2015;14(1):3-4. doi: 10.4161/15384101.2014.988107. No abstract available.

8.

Phosphorylation of eIF4GII and 4E-BP1 in response to nocodazole treatment: a reappraisal of translation initiation during mitosis.

Coldwell MJ, Cowan JL, Vlasak M, Mead A, Willett M, Perry LS, Morley SJ.

Cell Cycle. 2013 Dec 1;12(23):3615-28. doi: 10.4161/cc.26588. Epub 2013 Oct 1.

9.

SLiMPrints: conservation-based discovery of functional motif fingerprints in intrinsically disordered protein regions.

Davey NE, Cowan JL, Shields DC, Gibson TJ, Coldwell MJ, Edwards RJ.

Nucleic Acids Res. 2012 Nov;40(21):10628-41. doi: 10.1093/nar/gks854. Epub 2012 Sep 12.

10.

Multiple isoforms of the translation initiation factor eIF4GII are generated via use of alternative promoters, splice sites and a non-canonical initiation codon.

Coldwell MJ, Sack U, Cowan JL, Barrett RM, Vlasak M, Sivakumaran K, Morley SJ.

Biochem J. 2012 Nov 15;448(1):1-11. doi: 10.1042/BJ20111765.

PMID:
22909319
11.

Cytoplasmic mRNA: move it, use it or lose it!

Coldwell MJ, Gray NK, Brook M.

Biochem Soc Trans. 2010 Dec;38(6):1495-9. doi: 10.1042/BST0381495.

PMID:
21118114
12.

Inhibition of mammalian target of rapamycin (mTOR) signalling in C2C12 myoblasts prevents myogenic differentiation without affecting the hyperphosphorylation of 4E-BP1.

Willett M, Cowan JL, Vlasak M, Coldwell MJ, Morley SJ.

Cell Signal. 2009 Oct;21(10):1504-12. doi: 10.1016/j.cellsig.2009.05.009. Epub 2009 May 27.

PMID:
19481146
13.

Canonical initiation factor requirements of the Myc family of internal ribosome entry segments.

Spriggs KA, Cobbold LC, Jopling CL, Cooper RE, Wilson LA, Stoneley M, Coldwell MJ, Poncet D, Shen YC, Morley SJ, Bushell M, Willis AE.

Mol Cell Biol. 2009 Mar;29(6):1565-74. doi: 10.1128/MCB.01283-08. Epub 2009 Jan 5.

14.

A cunning stunt: an alternative mechanism of eukaryotic translation initiation.

Morley SJ, Coldwell MJ.

Sci Signal. 2008 Jun 24;1(25):pe32. doi: 10.1126/scisignal.125pe32.

PMID:
18577757
15.

Regulation of BAG-1 IRES-mediated translation following chemotoxic stress.

Dobbyn HC, Hill K, Hamilton TL, Spriggs KA, Pickering BM, Coldwell MJ, de Moor CH, Bushell M, Willis AE.

Oncogene. 2008 Feb 14;27(8):1167-74. Epub 2007 Aug 13.

16.

Functional analysis of individual binding activities of the scaffold protein eIF4G.

Hinton TM, Coldwell MJ, Carpenter GA, Morley SJ, Pain VM.

J Biol Chem. 2007 Jan 19;282(3):1695-708. Epub 2006 Nov 27.

17.

Specific isoforms of translation initiation factor 4GI show differences in translational activity.

Coldwell MJ, Morley SJ.

Mol Cell Biol. 2006 Nov;26(22):8448-60. Epub 2006 Sep 18.

18.

Initiation factor modifications in the preapoptotic phase.

Morley SJ, Coldwell MJ, Clemens MJ.

Cell Death Differ. 2005 Jun;12(6):571-84. Review.

19.

Expression of fragments of translation initiation factor eIF4GI reveals a nuclear localisation signal within the N-terminal apoptotic cleavage fragment N-FAG.

Coldwell MJ, Hashemzadeh-Bonehi L, Hinton TM, Morley SJ, Pain VM.

J Cell Sci. 2004 May 15;117(Pt 12):2545-55. Epub 2004 May 5.

20.

The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr.

Mitchell SA, Spriggs KA, Coldwell MJ, Jackson RJ, Willis AE.

Mol Cell. 2003 Mar;11(3):757-71.

21.

The p36 isoform of BAG-1 is translated by internal ribosome entry following heat shock.

Coldwell MJ, deSchoolmeester ML, Fraser GA, Pickering BM, Packham G, Willis AE.

Oncogene. 2001 Jul 5;20(30):4095-100.

22.
23.

Initiation of Apaf-1 translation by internal ribosome entry.

Coldwell MJ, Mitchell SA, Stoneley M, MacFarlane M, Willis AE.

Oncogene. 2000 Feb 17;19(7):899-905.

24.

Analysis of the c-myc IRES; a potential role for cell-type specific trans-acting factors and the nuclear compartment.

Stoneley M, Subkhankulova T, Le Quesne JP, Coldwell MJ, Jopling CL, Belsham GJ, Willis AE.

Nucleic Acids Res. 2000 Feb 1;28(3):687-94.

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