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Items: 14


Meroterpenoids from Neosetophoma sp.: A Dioxa[4.3.3]propellane Ring System, Potent Cytotoxicity, and Prolific Expression.

El-Elimat T, Raja HA, Ayers S, Kurina SJ, Burdette JE, Mattes Z, Sabatelle R, Bacon JW, Colby AH, Grinstaff MW, Pearce CJ, Oberlies NH.

Org Lett. 2019 Jan 8. doi: 10.1021/acs.orglett.8b03769. [Epub ahead of print]


SUV39H1 represses the expression of cytotoxic T-lymphocyte effector genes to promote colon tumor immune evasion.

Lu C, Yang D, Klement JD, Oh IK, Savage NM, Waller JL, Colby AH, Grinstaff M, Oberlies NH, Pearce C, Xie Z, Kulp SK, Coss CC, Phelps MA, Albers T, Lebedyeva I, Liu K.

Cancer Immunol Res. 2019 Jan 4. pii: canimm.0126.2018. doi: 10.1158/2326-6066.CIR-18-0126. [Epub ahead of print]


Nanoparticle-mediated lysosomal reacidification restores mitochondrial turnover and function in β cells under lipotoxicity.

Assali EA, Shlomo D, Zeng J, Taddeo EP, Trudeau KM, Erion KA, Colby AH, Grinstaff MW, Liesa M, Las G, Shirihai OS.

FASEB J. 2018 Dec 14:fj201801292R. doi: 10.1096/fj.201801292R. [Epub ahead of print]


Nucleic acid nanomedicines in Phase II/III clinical trials: translation of nucleic acid therapies for reprogramming cells.

Herrera VL, Colby AH, Ruiz-Opazo N, Coleman DG, Grinstaff MW.

Nanomedicine (Lond). 2018 Aug;13(16):2083-2098. doi: 10.2217/nnm-2018-0122. Epub 2018 Sep 11. Review.


Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells.

Lu C, Yang D, Sabbatini ME, Colby AH, Grinstaff MW, Oberlies NH, Pearce C, Liu K.

BMC Cancer. 2018 Feb 6;18(1):149. doi: 10.1186/s12885-018-4061-y.


Nanoparticle drug-delivery systems for peritoneal cancers: a case study of the design, characterization and development of the expansile nanoparticle.

Colby AH, Oberlies NH, Pearce CJ, Herrera VL, Colson YL, Grinstaff MW.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 May;9(3). doi: 10.1002/wnan.1451. Epub 2017 Feb 9. Review.


Highly Specific and Sensitive Fluorescent Nanoprobes for Image-Guided Resection of Sub-Millimeter Peritoneal Tumors.

Colby AH, Berry SM, Moran AM, Pasion KA, Liu R, Colson YL, Ruiz-Opazo N, Grinstaff MW, Herrera VL.

ACS Nano. 2017 Feb 28;11(2):1466-1477. doi: 10.1021/acsnano.6b06777. Epub 2017 Feb 1.


Lysosome acidification by photoactivated nanoparticles restores autophagy under lipotoxicity.

Trudeau KM, Colby AH, Zeng J, Las G, Feng JH, Grinstaff MW, Shirihai OS.

J Cell Biol. 2016 Jul 4;214(1):25-34. doi: 10.1083/jcb.201511042.


Nanoparticle tumor localization, disruption of autophagosomal trafficking, and prolonged drug delivery improve survival in peritoneal mesothelioma.

Liu R, Colby AH, Gilmore D, Schulz M, Zeng J, Padera RF, Shirihai O, Grinstaff MW, Colson YL.

Biomaterials. 2016 Sep;102:175-86. doi: 10.1016/j.biomaterials.2016.06.031. Epub 2016 Jun 23.


Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis.

Herrera VL, Colby AH, Tan GA, Moran AM, O'Brien MJ, Colson YL, Ruiz-Opazo N, Grinstaff MW.

Nanomedicine (Lond). 2016 May;11(9):1001-15. doi: 10.2217/nnm-2015-0023. Epub 2016 Apr 14.


Two-Step Delivery: Exploiting the Partition Coefficient Concept to Increase Intratumoral Paclitaxel Concentrations In vivo Using Responsive Nanoparticles.

Colby AH, Liu R, Schulz MD, Padera RF, Colson YL, Grinstaff MW.

Sci Rep. 2016 Jan 7;6:18720. doi: 10.1038/srep18720.


Synthesis and Characterization of Hybrid Polymer/Lipid Expansile Nanoparticles: Imparting Surface Functionality for Targeting and Stability.

Stolzoff M, Ekladious I, Colby AH, Colson YL, Porter TM, Grinstaff MW.

Biomacromolecules. 2015 Jul 13;16(7):1958-66. doi: 10.1021/acs.biomac.5b00336. Epub 2015 Jun 19.


Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles.

Colby AH, Colson YL, Grinstaff MW.

Nanoscale. 2013 Apr 21;5(8):3496-504. doi: 10.1039/c3nr00114h. Epub 2013 Mar 13.


Tunable pores for measuring concentrations of synthetic and biological nanoparticle dispersions.

Roberts GS, Yu S, Zeng Q, Chan LC, Anderson W, Colby AH, Grinstaff MW, Reid S, Vogel R.

Biosens Bioelectron. 2012 Jan 15;31(1):17-25. doi: 10.1016/j.bios.2011.09.040. Epub 2011 Oct 5.


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