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Items: 1 to 50 of 58

1.

Proresolving mediators LXB4 and RvE1 regulate inflammation in stromal cells from patients with shoulder tendon tears.

Dakin SG, Colas RA, Wheway K, Watkins B, Appleton L, Rees J, Gwilym S, Little C, Dalli J, Carr AJ.

Am J Pathol. 2019 Aug 19. pii: S0002-9440(19)30667-4. doi: 10.1016/j.ajpath.2019.07.011. [Epub ahead of print]

PMID:
31437425
2.

Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction.

Fosshaug LE, Colas RA, Anstensrud AK, Gregersen I, Nymo S, Sagen EL, Michelsen A, Vinge LE, Øie E, Gullestad L, Halvorsen B, Hansen TV, Aukrust P, Dalli J, Yndestad A.

EBioMedicine. 2019 Aug;46:264-273. doi: 10.1016/j.ebiom.2019.07.024. Epub 2019 Jul 22.

3.

Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis.

Flak MB, Colas RA, Muñoz-Atienza E, Curtis MA, Dalli J, Pitzalis C.

JCI Insight. 2019 Jul 11;4(13). pii: 125191. doi: 10.1172/jci.insight.125191. eCollection 2019 Jul 11.

4.

Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells.

Holopainen M, Colas RA, Valkonen S, Tigistu-Sahle F, Hyvärinen K, Mazzacuva F, Lehenkari P, Käkelä R, Dalli J, Kerkelä E, Laitinen S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1350-1362. doi: 10.1016/j.bbalip.2019.06.010. Epub 2019 Jun 15.

PMID:
31207356
5.

Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock.

Sordi R, Chiazza F, Collotta D, Migliaretti G, Colas RA, Vulliamy P, Brohi K, Dalli J, Collino M, Thiemermann C.

Ann Surg. 2019 Jun 7. doi: 10.1097/SLA.0000000000003407. [Epub ahead of print]

PMID:
31188196
6.

Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules.

Valkonen S, Holopainen M, Colas RA, Impola U, Dalli J, Käkelä R, Siljander PR, Laitinen S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Aug;1864(8):1168-1182. doi: 10.1016/j.bbalip.2019.03.011. Epub 2019 Apr 10.

PMID:
30980920
7.

15-Epi-LXA4 and MaR1 counter inflammation in stromal cells from patients with Achilles tendinopathy and rupture.

Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L, Wheway K, Watkins B, Dalli J, Carr AJ.

FASEB J. 2019 Jul;33(7):8043-8054. doi: 10.1096/fj.201900196R. Epub 2019 Mar 27.

8.

Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA.

Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN, Kalesse M, Hansen TV.

Chemistry. 2019 Jan 28;25(6):1476-1480. doi: 10.1002/chem.201806029. Epub 2018 Dec 20.

PMID:
30511787
9.

n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis.

Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K, Aronica E, Porcu L, Pistorius K, Colas RA, Hansen TV, Perretti M, Kaminski RM, Dalli J, Vezzani A.

Brain. 2018 Nov 1;141(11):3130-3143. doi: 10.1093/brain/awy247.

10.

Synthesis of protectin D1 analogs: novel pro-resolution and radiotracer agents.

Tungen JE, Aursnes M, Ramon S, Colas RA, Serhan CN, Olberg DE, Nuruddin S, Willoch F, Hansen TV.

Org Biomol Chem. 2018 Sep 19;16(36):6818-6823. doi: 10.1039/c8ob01232f.

PMID:
30204204
11.

PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function.

Pistorius K, Souza PR, De Matteis R, Austin-Williams S, Primdahl KG, Vik A, Mazzacuva F, Colas RA, Marques RM, Hansen TV, Dalli J.

Cell Chem Biol. 2018 Jun 21;25(6):749-760.e9. doi: 10.1016/j.chembiol.2018.04.017. Epub 2018 May 24.

12.

Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation.

Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RP, Serhan CN, Gilroy DW.

JCI Insight. 2018 Mar 22;3(6). pii: 94463. doi: 10.1172/jci.insight.94463.

13.

A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults.

Mai NT, Dobbs N, Phu NH, Colas RA, Thao LT, Thuong NT, Nghia HD, Hanh NH, Hang NT, Heemskerk AD, Day JN, Ly L, Thu DD, Merson L, Kestelyn E, Wolbers M, Geskus R, Summers D, Chau NV, Dalli J, Thwaites GE.

Elife. 2018 Feb 27;7. pii: e33478. doi: 10.7554/eLife.33478.

14.

Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis.

Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J, Thiemermann C, Ahluwalia A.

FASEB J. 2018 Jul;32(7):3816-3831. doi: 10.1096/fj.201701303R. Epub 2018 Feb 20.

PMID:
29465314
15.

Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease.

Colas RA, Souza PR, Walker ME, Burton M, Zasłona Z, Curtis AM, Marques RM, Dalli J.

Circ Res. 2018 Mar 16;122(6):855-863. doi: 10.1161/CIRCRESAHA.117.312472. Epub 2018 Feb 5.

16.

Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis.

Dalli J, Colas RA, Walker ME, Serhan CN.

Methods Mol Biol. 2018;1730:59-72. doi: 10.1007/978-1-4939-7592-1_4.

PMID:
29363065
17.

Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2.

Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F, Jelicks LA, Matos Dos Santos F, Nagajyothi J, Zingman MA, Reyes J, Weiss LM, Serhan CN, Tanowitz HB.

Infect Immun. 2018 Mar 22;86(4). pii: e00688-17. doi: 10.1128/IAI.00688-17. Print 2018 Apr.

18.

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

Bowden JA, Heckert A, Ulmer CZ, Jones CM, Koelmel JP, Abdullah L, Ahonen L, Alnouti Y, Armando AM, Asara JM, Bamba T, Barr JR, Bergquist J, Borchers CH, Brandsma J, Breitkopf SB, Cajka T, Cazenave-Gassiot A, Checa A, Cinel MA, Colas RA, Cremers S, Dennis EA, Evans JE, Fauland A, Fiehn O, Gardner MS, Garrett TJ, Gotlinger KH, Han J, Huang Y, Neo AH, Hyötyläinen T, Izumi Y, Jiang H, Jiang H, Jiang J, Kachman M, Kiyonami R, Klavins K, Klose C, Köfeler HC, Kolmert J, Koal T, Koster G, Kuklenyik Z, Kurland IJ, Leadley M, Lin K, Maddipati KR, McDougall D, Meikle PJ, Mellett NA, Monnin C, Moseley MA, Nandakumar R, Oresic M, Patterson R, Peake D, Pierce JS, Post M, Postle AD, Pugh R, Qiu Y, Quehenberger O, Ramrup P, Rees J, Rembiesa B, Reynaud D, Roth MR, Sales S, Schuhmann K, Schwartzman ML, Serhan CN, Shevchenko A, Somerville SE, St John-Williams L, Surma MA, Takeda H, Thakare R, Thompson JW, Torta F, Triebl A, Trötzmüller M, Ubhayasekera SJK, Vuckovic D, Weir JM, Welti R, Wenk MR, Wheelock CE, Yao L, Yuan M, Zhao XH, Zhou S.

J Lipid Res. 2017 Dec;58(12):2275-2288. doi: 10.1194/jlr.M079012. Epub 2017 Oct 6.

19.

Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA.

Primdahl KG, Tungen JE, De Souza PRS, Colas RA, Dalli J, Hansen TV, Vik A.

Org Biomol Chem. 2017 Oct 18;15(40):8606-8613. doi: 10.1039/c7ob02113e.

PMID:
28980694
20.

Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy.

Dakin SG, Ly L, Colas RA, Oppermann U, Wheway K, Watkins B, Dalli J, Carr AJ.

Sci Rep. 2017 Sep 8;7(1):11009. doi: 10.1038/s41598-017-11188-y.

21.

Albumin Counteracts Immune-Suppressive Effects of Lipid Mediators in Patients With Advanced Liver Disease.

China L, Maini A, Skene SS, Shabir Z, Sylvestre Y, Colas RA, Ly L, Becares Salles N, Belloti V, Dalli J, Gilroy DW, O'Brien A.

Clin Gastroenterol Hepatol. 2018 May;16(5):738-747.e7. doi: 10.1016/j.cgh.2017.08.027. Epub 2017 Aug 30.

22.

13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis.

Walker ME, Souza PR, Colas RA, Dalli J.

FASEB J. 2017 Aug;31(8):3636-3648. doi: 10.1096/fj.201700268. Epub 2017 May 2.

23.

Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection.

Gobbetti T, Dalli J, Colas RA, Federici Canova D, Aursnes M, Bonnet D, Alric L, Vergnolle N, Deraison C, Hansen TV, Serhan CN, Perretti M.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3963-3968. doi: 10.1073/pnas.1617290114. Epub 2017 Mar 29.

24.

NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B4 Synthesis.

Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon JS, Shinohara M, Hisata S, Howrylak JA, Suh GY, Ryter SW, Serhan CN, Choi AMK.

Am J Respir Crit Care Med. 2017 Sep 15;196(6):713-726. doi: 10.1164/rccm.201604-0892OC.

25.

Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution.

Dalli J, Colas RA, Arnardottir H, Serhan CN.

Immunity. 2017 Jan 17;46(1):92-105. doi: 10.1016/j.immuni.2016.12.009. Epub 2017 Jan 5.

26.

Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans.

Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC, Bansal J, Pitrola K, Shaw C, D'Acquisto F, Colas RA, Marelli-Berg F, Dalli J, Ahluwalia A.

J Clin Invest. 2017 Jan 3;127(1):169-182. doi: 10.1172/JCI89429. Epub 2016 Nov 28.

27.

Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation.

Colas RA, Dalli J, Chiang N, Vlasakov I, Sanger JM, Riley IR, Serhan CN.

J Immunol. 2016 Dec 1;197(11):4444-4452. Epub 2016 Oct 31.

28.

Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins.

Primdahl KG, Aursnes M, Walker ME, Colas RA, Serhan CN, Dalli J, Hansen TV, Vik A.

J Nat Prod. 2016 Oct 28;79(10):2693-2702. Epub 2016 Oct 5.

29.

An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques.

Fredman G, Hellmann J, Proto JD, Kuriakose G, Colas RA, Dorweiler B, Connolly ES, Solomon R, Jones DM, Heyer EJ, Spite M, Tabas I.

Nat Commun. 2016 Sep 23;7:12859. doi: 10.1038/ncomms12859.

30.

Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes.

Dalli J, Colas RA, Quintana C, Barragan-Bradford D, Hurwitz S, Levy BD, Choi AM, Serhan CN, Baron RM.

Crit Care Med. 2017 Jan;45(1):58-68.

31.

Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation.

Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M, Serhan CN.

J Immunol. 2016 Sep 15;197(6):2362-8. doi: 10.4049/jimmunol.1502268. Epub 2016 Aug 17.

32.

Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators.

Tsoyi K, Hall SR, Dalli J, Colas RA, Ghanta S, Ith B, Coronata A, Fredenburgh LE, Baron RM, Choi AM, Serhan CN, Liu X, Perrella MA.

Crit Care Med. 2016 Dec;44(12):e1236-e1245.

33.

Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension.

Liu F, Haeger CM, Dieffenbach PB, Sicard D, Chrobak I, Coronata AM, Suárez Velandia MM, Vitali S, Colas RA, Norris PC, Marinković A, Liu X, Ma J, Rose CD, Lee SJ, Comhair SA, Erzurum SC, McDonald JD, Serhan CN, Walsh SR, Tschumperlin DJ, Fredenburgh LE.

JCI Insight. 2016 Jun 2;1(8). pii: e86987.

34.

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia.

Colby JK, Abdulnour RE, Sham HP, Dalli J, Colas RA, Winkler JW, Hellmann J, Wong B, Cui Y, El-Chemaly S, Petasis NA, Spite M, Serhan CN, Levy BD.

Am J Pathol. 2016 Jul;186(7):1801-1813. doi: 10.1016/j.ajpath.2016.03.011. Epub 2016 May 10.

35.

Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling.

Elajami TK, Colas RA, Dalli J, Chiang N, Serhan CN, Welty FK.

FASEB J. 2016 Aug;30(8):2792-801. doi: 10.1096/fj.201500155R. Epub 2016 Apr 27.

36.

Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes.

Wang CW, Colas RA, Dalli J, Arnardottir HH, Nguyen D, Hasturk H, Chiang N, Van Dyke TE, Serhan CN.

Infect Immun. 2015 Dec 14;84(3):658-65. doi: 10.1128/IAI.01131-15.

37.

Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis.

Zhu M, Wang X, Hjorth E, Colas RA, Schroeder L, Granholm AC, Serhan CN, Schultzberg M.

Mol Neurobiol. 2016 May;53(4):2733-49. doi: 10.1007/s12035-015-9544-0. Epub 2015 Dec 9.

38.

Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation.

Abdulnour RE, Sham HP, Douda DN, Colas RA, Dalli J, Bai Y, Ai X, Serhan CN, Levy BD.

Mucosal Immunol. 2016 Sep;9(5):1278-87. doi: 10.1038/mi.2015.129. Epub 2015 Dec 9.

39.

Human Periodontal Stem Cells Release Specialized Proresolving Mediators and Carry Immunomodulatory and Prohealing Properties Regulated by Lipoxins.

Cianci E, Recchiuti A, Trubiani O, Diomede F, Marchisio M, Miscia S, Colas RA, Dalli J, Serhan CN, Romano M.

Stem Cells Transl Med. 2016 Jan;5(1):20-32. doi: 10.5966/sctm.2015-0163. Epub 2015 Nov 25.

40.

Stretching Impacts Inflammation Resolution in Connective Tissue.

Berrueta L, Muskaj I, Olenich S, Butler T, Badger GJ, Colas RA, Spite M, Serhan CN, Langevin HM.

J Cell Physiol. 2016 Jul;231(7):1621-7. doi: 10.1002/jcp.25263. Epub 2015 Dec 10.

41.

Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages.

Aursnes M, Tungen JE, Colas RA, Vlasakov I, Dalli J, Serhan CN, Hansen TV.

J Nat Prod. 2015 Dec 24;78(12):2924-31. doi: 10.1021/acs.jnatprod.5b00574. Epub 2015 Nov 18.

42.

Resolvin D1 Reduces Emphysema and Chronic Inflammation.

Hsiao HM, Thatcher TH, Colas RA, Serhan CN, Phipps RP, Sime PJ.

Am J Pathol. 2015 Dec;185(12):3189-201. doi: 10.1016/j.ajpath.2015.08.008. Epub 2015 Oct 24.

43.

Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages.

Croasdell A, Thatcher TH, Kottmann RM, Colas RA, Dalli J, Serhan CN, Sime PJ, Phipps RP.

Am J Physiol Lung Cell Mol Physiol. 2015 Oct 15;309(8):L888-901. doi: 10.1152/ajplung.00125.2015. Epub 2015 Aug 21.

44.

Identification of resolvin D2 receptor mediating resolution of infections and organ protection.

Chiang N, Dalli J, Colas RA, Serhan CN.

J Exp Med. 2015 Jul 27;212(8):1203-17. doi: 10.1084/jem.20150225. Epub 2015 Jul 20.

45.

A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae.

Ramirez JL, de Almeida Oliveira G, Calvo E, Dalli J, Colas RA, Serhan CN, Ribeiro JM, Barillas-Mury C.

Nat Commun. 2015 Jun 23;6:7403. doi: 10.1038/ncomms8403.

46.

Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease.

Börgeson E, Johnson AM, Lee YS, Till A, Syed GH, Ali-Shah ST, Guiry PJ, Dalli J, Colas RA, Serhan CN, Sharma K, Godson C.

Cell Metab. 2015 Jul 7;22(1):125-37. doi: 10.1016/j.cmet.2015.05.003. Epub 2015 Jun 4.

47.

Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function.

Kain V, Ingle KA, Colas RA, Dalli J, Prabhu SD, Serhan CN, Joshi M, Halade GV.

J Mol Cell Cardiol. 2015 Jul;84:24-35. doi: 10.1016/j.yjmcc.2015.04.003. Epub 2015 Apr 11.

48.

Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent.

Orr SK, Colas RA, Dalli J, Chiang N, Serhan CN.

Am J Physiol Lung Cell Mol Physiol. 2015 May 1;308(9):L904-11. doi: 10.1152/ajplung.00370.2014. Epub 2015 Mar 13.

49.

Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways.

Dalli J, Ramon S, Norris PC, Colas RA, Serhan CN.

FASEB J. 2015 May;29(5):2120-36. doi: 10.1096/fj.14-268441. Epub 2015 Feb 20.

50.

The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide.

Dalli J, Kraft BD, Colas RA, Shinohara M, Fredenburgh LE, Hess DR, Chiang N, Welty-Wolf K, Choi AM, Piantadosi CA, Serhan CN.

Am J Respir Cell Mol Biol. 2015 Sep;53(3):314-25. doi: 10.1165/rcmb.2014-0299OC.

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