Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 98

1.

Changes in brain kynurenine levels via gut microbiota and gut-barrier disruption induced by chronic ethanol exposure in mice.

Giménez-Gómez P, Pérez-Hernández M, O'Shea E, Caso JR, Martín-Hernandez D, Cervera LA, Centelles MLG, Gutiérrez-Lopez MD, Colado MI.

FASEB J. 2019 Nov;33(11):12900-12914. doi: 10.1096/fj.201900491RR. Epub 2019 Sep 11.

PMID:
31509716
2.

Increasing kynurenine brain levels reduces ethanol consumption in mice by inhibiting dopamine release in nucleus accumbens.

Giménez-Gómez P, Pérez-Hernández M, Gutiérrez-López MD, Vidal R, Abuin-Martínez C, O'Shea E, Colado MI.

Neuropharmacology. 2018 Jun;135:581-591. doi: 10.1016/j.neuropharm.2018.04.016. Epub 2018 Apr 18.

PMID:
29705534
3.

Glutaminase and MMP-9 Downregulation in Cortex and Hippocampus of LPA1 Receptor Null Mice Correlate with Altered Dendritic Spine Plasticity.

Peñalver A, Campos-Sandoval JA, Blanco E, Cardona C, Castilla L, Martín-Rufián M, Estivill-Torrús G, Sánchez-Varo R, Alonso FJ, Pérez-Hernández M, Colado MI, Gutiérrez A, de Fonseca FR, Márquez J.

Front Mol Neurosci. 2017 Sep 5;10:278. doi: 10.3389/fnmol.2017.00278. eCollection 2017.

4.

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) produces edema due to BBB disruption induced by MMP-9 activation in rat hippocampus.

Pérez-Hernández M, Fernández-Valle ME, Rubio-Araiz A, Vidal R, Gutiérrez-López MD, O'Shea E, Colado MI.

Neuropharmacology. 2017 May 15;118:157-166. doi: 10.1016/j.neuropharm.2017.03.019. Epub 2017 Mar 16.

PMID:
28322979
5.

Disruption of blood-brain barrier integrity in postmortem alcoholic brain: preclinical evidence of TLR4 involvement from a binge-like drinking model.

Rubio-Araiz A, Porcu F, Pérez-Hernández M, García-Gutiérrez MS, Aracil-Fernández MA, Gutierrez-López MD, Guerri C, Manzanares J, O'Shea E, Colado MI.

Addict Biol. 2017 Jul;22(4):1103-1116. doi: 10.1111/adb.12376. Epub 2016 Mar 7.

PMID:
26949123
6.

Effects of repeated social defeat on adolescent mice on cocaine-induced CPP and self-administration in adulthood: integrity of the blood-brain barrier.

Rodríguez-Arias M, Montagud-Romero S, Rubio-Araiz A, Aguilar MA, Martín-García E, Cabrera R, Maldonado R, Porcu F, Colado MI, Miñarro J.

Addict Biol. 2017 Jan;22(1):129-141. doi: 10.1111/adb.12301. Epub 2015 Sep 16.

PMID:
26374627
7.

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) disrupts blood-brain barrier integrity through a mechanism involving P2X7 receptors.

Rubio-Araiz A, Perez-Hernandez M, Urrutia A, Porcu F, Borcel E, Gutierrez-Lopez MD, O'Shea E, Colado MI.

Int J Neuropsychopharmacol. 2014 Aug;17(8):1243-55. doi: 10.1017/S1461145714000145. Epub 2014 Mar 14.

PMID:
24626059
8.

Current preclinical studies on neuroinflammation and changes in blood-brain barrier integrity by MDMA and methamphetamine.

O'Shea E, Urrutia A, Green AR, Colado MI.

Neuropharmacology. 2014 Dec;87:125-34. doi: 10.1016/j.neuropharm.2014.02.015. Epub 2014 Mar 2. Review.

PMID:
24594477
9.

The JNK inhibitor, SP600125, potentiates the glial response and cell death induced by methamphetamine in the mouse striatum.

Urrutia A, Granado N, Gutierrez-Lopez MD, Moratalla R, O'Shea E, Colado MI.

Int J Neuropsychopharmacol. 2014 Feb;17(2):235-46. doi: 10.1017/S1461145713000850. Epub 2013 Oct 8.

10.

Cocaine potentiates MDMA-induced oxidative stress but not dopaminergic neurotoxicity in mice: implications for the pathogenesis of free radical-induced neurodegenerative disorders.

Peraile I, Granado N, Torres E, Gutiérrez-López MD, Moratalla R, Colado MI, O'Shea E.

Psychopharmacology (Berl). 2013 Nov;230(1):125-35. doi: 10.1007/s00213-013-3142-5. Epub 2013 May 17.

PMID:
23681166
11.

A study on the effect of JNK inhibitor, SP600125, on the disruption of blood-brain barrier induced by methamphetamine.

Urrutia A, Rubio-Araiz A, Gutierrez-Lopez MD, ElAli A, Hermann DM, O'Shea E, Colado MI.

Neurobiol Dis. 2013 Feb;50:49-58. doi: 10.1016/j.nbd.2012.10.006. Epub 2012 Oct 12.

PMID:
23069681
12.

Apolipoprotein-E controls adenosine triphosphate-binding cassette transporters ABCB1 and ABCC1 on cerebral microvessels after methamphetamine intoxication.

ElAli A, Urrutia A, Rubio-Araiz A, Hernandez-Jimenez M, Colado MI, Doeppner TR, Hermann DM.

Stroke. 2012 Jun;43(6):1647-53. doi: 10.1161/STROKEAHA.111.648923. Epub 2012 Mar 15.

PMID:
22426312
13.

Changes in the serotonergic system and in brain-derived neurotrophic factor distribution in the main olfactory bulb of pcd mice before and after mitral cell loss.

Gómez C, Curto GG, Baltanás FC, Valero J, O'Shea E, Colado MI, Díaz D, Weruaga E, Alonso JR.

Neuroscience. 2012 Jan 10;201:20-33. doi: 10.1016/j.neuroscience.2011.11.025. Epub 2011 Nov 20.

PMID:
22133893
14.

Dopamine D(1) receptor deletion strongly reduces neurotoxic effects of methamphetamine.

Ares-Santos S, Granado N, Oliva I, O'Shea E, Martin ED, Colado MI, Moratalla R.

Neurobiol Dis. 2012 Feb;45(2):810-20. doi: 10.1016/j.nbd.2011.11.005. Epub 2011 Nov 13.

PMID:
22115942
15.

Increased interleukin-1β levels following low dose MDMA induces tolerance against the 5-HT neurotoxicity produced by challenge MDMA.

Mayado A, Torres E, Gutierrez-Lopez MD, Colado MI, O'Shea E.

J Neuroinflammation. 2011 Nov 24;8:165. doi: 10.1186/1742-2094-8-165.

16.

Changes in interleukin-1 signal modulators induced by 3,4-methylenedioxymethamphetamine (MDMA): regulation by CB2 receptors and implications for neurotoxicity.

Torres E, Gutierrez-Lopez MD, Mayado A, Rubio A, O'Shea E, Colado MI.

J Neuroinflammation. 2011 May 19;8:53. doi: 10.1186/1742-2094-8-53.

17.

Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA.

Granado N, Ares-Santos S, Oliva I, O'Shea E, Martin ED, Colado MI, Moratalla R.

Neurobiol Dis. 2011 Jun;42(3):391-403. doi: 10.1016/j.nbd.2011.01.033. Epub 2011 Feb 15.

PMID:
21303698
18.

Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine.

Gutierrez-Lopez MD, Llopis N, Feng S, Barrett DA, O'Shea E, Colado MI.

Br J Pharmacol. 2010 Jun;160(3):772-83. doi: 10.1111/j.1476-5381.2010.00720.x.

19.

Sex-dependent maternal deprivation effects on brain monoamine content in adolescent rats.

Llorente R, O'Shea E, Gutierrez-Lopez MD, Llorente-Berzal A, Colado MI, Viveros MP.

Neurosci Lett. 2010 Jul 26;479(2):112-7. doi: 10.1016/j.neulet.2010.05.039. Epub 2010 May 20.

PMID:
20493239
20.

Evidence that MDMA ('ecstasy') increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brain.

Torres E, Gutierrez-Lopez MD, Borcel E, Peraile I, Mayado A, O'Shea E, Colado MI.

J Neurochem. 2010 Apr;113(1):67-78. doi: 10.1111/j.1471-4159.2010.06578.x. Epub 2010 Jan 12.

21.

Dopamine transporter down-regulation following repeated cocaine: implications for 3,4-methylenedioxymethamphetamine-induced acute effects and long-term neurotoxicity in mice.

Peraile I, Torres E, Mayado A, Izco M, Lopez-Jimenez A, Lopez-Moreno JA, Colado MI, O'Shea E.

Br J Pharmacol. 2010 Jan;159(1):201-11. doi: 10.1111/j.1476-5381.2009.00522.x. Epub 2009 Dec 10.

22.

Administration of neurotoxic doses of MDMA reduces sensitivity to ethanol and increases GAT-1 immunoreactivity in mice striatum.

Izco M, Gutierrez-Lopez MD, Marchant I, O'Shea E, Colado MI.

Psychopharmacology (Berl). 2010 Jan;207(4):671-9. doi: 10.1007/s00213-009-1699-9. Epub 2009 Oct 20.

PMID:
19841904
23.

A study on the mechanisms by which minocycline protects against MDMA ('ecstasy')-induced neurotoxicity of 5-HT cortical neurons.

Orio L, Llopis N, Torres E, Izco M, O'Shea E, Colado MI.

Neurotox Res. 2010 Aug;18(2):187-99. doi: 10.1007/s12640-009-9120-3. Epub 2009 Sep 24.

PMID:
19777321
24.

Selective vulnerability in striosomes and in the nigrostriatal dopaminergic pathway after methamphetamine administration : early loss of TH in striosomes after methamphetamine.

Granado N, Ares-Santos S, O'Shea E, Vicario-Abejón C, Colado MI, Moratalla R.

Neurotox Res. 2010 Jul;18(1):48-58. doi: 10.1007/s12640-009-9106-1. Epub 2009 Sep 4.

25.

Administration of MDMA to ethanol-deprived rats increases ethanol operant self-administration and dopamine release during reinstatement.

Moreno-Sanz G, O'Shea E, Orio L, Escobedo I, González-Cuevas G, Navarro M, Colado MI, López-Moreno JA.

Int J Neuropsychopharmacol. 2009 Aug;12(7):929-40. doi: 10.1017/S1461145709009912. Epub 2009 Feb 23.

PMID:
19236733
26.

Persistent MDMA-induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice.

Granado N, O'Shea E, Bove J, Vila M, Colado MI, Moratalla R.

J Neurochem. 2008 Nov;107(4):1102-12. doi: 10.1111/j.1471-4159.2008.05705.x. Epub 2008 Sep 24.

27.

Mice with decreased cerebral dopamine function following a neurotoxic dose of MDMA (3,4-methylenedioxymethamphetamine, "Ecstasy") exhibit increased ethanol consumption and preference.

Izco M, Marchant I, Escobedo I, Peraile I, Delgado M, Higuera-Matas A, Olias O, Ambrosio E, O'Shea E, Colado MI.

J Pharmacol Exp Ther. 2007 Sep;322(3):1003-12. Epub 2007 May 25.

PMID:
17526809
28.

Sex differences in catechol contents in the olfactory bulb of control and unilaterally deprived rats.

Gómez C, Briñón JG, Valero J, Recio JS, Murias AR, Curto GG, Orio L, Colado MI, Alonso JR.

Eur J Neurosci. 2007 Mar;25(5):1517-28.

PMID:
17425578
29.

Evidence for a role of Hsp70 in the neuroprotection induced by heat shock pre-treatment against 3,4-methylenedioxymethamphetamine toxicity in rat brain.

Escobedo I, Peraile I, Orio L, Colado MI, O'Shea E.

J Neurochem. 2007 Jun;101(5):1272-83. Epub 2007 Feb 27.

30.

Changes in the serotonergic system in the main olfactory bulb of rats unilaterally deprived from birth to adulthood.

Gómez C, Briñón JG, Orio L, Colado MI, Lawrence AJ, Zhou FC, Vidal M, Barbado MV, Alonso JR.

J Neurochem. 2007 Feb;100(4):924-38.

31.

Factors contributing to the enhancement of MDMA-induced 5-HT depletion by ethanol: a reply to Byron and Cassel.

O'Shea E, Colado MI.

Psychopharmacology (Berl). 2007 Mar;190(4):581-2. Epub 2007 Jan 19. No abstract available.

PMID:
17235607
32.

Binge ethanol administration enhances the MDMA-induced long-term 5-HT neurotoxicity in rat brain.

Izco M, Orio L, O'Shea E, Colado MI.

Psychopharmacology (Berl). 2007 Jan;189(4):459-70. Epub 2006 Oct 18.

PMID:
17047928
33.

Differential effects of unilateral olfactory deprivation on noradrenergic and cholinergic systems in the main olfactory bulb of the rat.

Gómez C, Briñón JG, Colado MI, Orio L, Vidal M, Barbado MV, Alonso JR.

Neuroscience. 2006 Sep 15;141(4):2117-28. Epub 2006 Jun 30.

PMID:
16809000
34.

MDMA-induced neurotoxicity: long-term effects on 5-HT biosynthesis and the influence of ambient temperature.

O'Shea E, Orio L, Escobedo I, Sanchez V, Camarero J, Green AR, Colado MI.

Br J Pharmacol. 2006 Jul;148(6):778-85. Epub 2006 Jun 12.

35.

The acute and long-term neurotoxic effects of MDMA on marble burying behaviour in mice.

Saadat KS, Elliott JM, Colado MI, Green AR.

J Psychopharmacol. 2006 Mar;20(2):264-71.

PMID:
16510484
37.

Studies on the effect of MDMA ('ecstasy') on the body temperature of rats housed at different ambient room temperatures.

Green AR, O'Shea E, Saadat KS, Elliott JM, Colado MI.

Br J Pharmacol. 2005 Sep;146(2):306-12.

38.

Elevation of ambient room temperature has differential effects on MDMA-induced 5-HT and dopamine release in striatum and nucleus accumbens of rats.

O'Shea E, Escobedo I, Orio L, Sanchez V, Navarro M, Green AR, Colado MI.

Neuropsychopharmacology. 2005 Jul;30(7):1312-23.

39.

A comparative study on the acute and long-term effects of MDMA and 3,4-dihydroxymethamphetamine (HHMA) on brain monoamine levels after i.p. or striatal administration in mice.

Escobedo I, O'Shea E, Orio L, Sanchez V, Segura M, de la Torre R, Farre M, Green AR, Colado MI.

Br J Pharmacol. 2005 Jan;144(2):231-41.

40.

The role of 5-HT in the impairment of thermoregulation observed in rats administered MDMA ('ecstasy') when housed at high ambient temperature.

Saadat KS, O'shea E, Colado MI, Elliott JM, Green AR.

Psychopharmacology (Berl). 2005 Jun;179(4):884-90. Epub 2005 Jan 14.

PMID:
15650843
41.

A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response.

Green AR, O'shea E, Colado MI.

Eur J Pharmacol. 2004 Oct 1;500(1-3):3-13. Review.

PMID:
15464016
42.

Effect of repeated ('binge') dosing of MDMA to rats housed at normal and high temperature on neurotoxic damage to cerebral 5-HT and dopamine neurones.

Sanchez V, O'shea E, Saadat KS, Elliott JM, Colado MI, Green AR.

J Psychopharmacol. 2004 Sep;18(3):412-6.

PMID:
15358986
43.

3,4-Methylenedioxymethamphetamine increases interleukin-1beta levels and activates microglia in rat brain: studies on the relationship with acute hyperthermia and 5-HT depletion.

Orio L, O'Shea E, Sanchez V, Pradillo JM, Escobedo I, Camarero J, Moro MA, Green AR, Colado MI.

J Neurochem. 2004 Jun;89(6):1445-53.

44.

Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function.

Colado MI, O'Shea E, Green AR.

Psychopharmacology (Berl). 2004 May;173(3-4):249-63. Epub 2004 Apr 9. Review.

PMID:
15083264
45.

Effect of ambient temperature and a prior neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA) on the hyperthermic response of rats to a single or repeated ('binge' ingestion) low dose of MDMA.

Green AR, Sanchez V, O'Shea E, Saadat KS, Elliott JM, Colado MI.

Psychopharmacology (Berl). 2004 May;173(3-4):264-9. Epub 2004 Jan 15.

PMID:
14726996
46.

Hyperthermic and neurotoxic effect of 3,4-methylenedioxymethamphetamine (MDMA) in guinea pigs.

Saadat KS, Elliott JM, Colado MI, Green AR.

Psychopharmacology (Berl). 2004 May;173(3-4):452-3. Epub 2003 Dec 9. No abstract available.

PMID:
14663549
47.

Inhibition of glutamate release by delaying ATP fall accounts for neuroprotective effects of antioxidants in experimental stroke.

Hurtado O, De Cristóbal J, Sánchez V, Lizasoain I, Cárdenas A, Pereira MP, Colado MI, Leza JC, Lorenzo P, Moro MA.

FASEB J. 2003 Nov;17(14):2082-4. Epub 2003 Sep 18.

PMID:
14500556
48.

The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").

Green AR, Mechan AO, Elliott JM, O'Shea E, Colado MI.

Pharmacol Rev. 2003 Sep;55(3):463-508. Epub 2003 Jul 17. Review.

PMID:
12869661
49.

Is frequent dosing with ecstasy a risky business for dopamine-containing neurons?

O'Shea E, Colado MI.

Trends Pharmacol Sci. 2003 Jun;24(6):272-4.

PMID:
12823951
50.

The nNOS inhibitor, AR-R17477AR, prevents the loss of NF68 immunoreactivity induced by methamphetamine in the mouse striatum.

Sanchez V, Zeini M, Camarero J, O'Shea E, Bosca L, Green AR, Colado MI.

J Neurochem. 2003 Apr;85(2):515-24.

Supplemental Content

Loading ...
Support Center