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Items: 32

1.

ADAMTS-12 metalloprotease is necessary for normal inflammatory response.

Moncada-Pazos A, Obaya AJ, Llamazares M, Heljasvaara R, Suárez MF, Colado E, Noël A, Cal S, López-Otín C.

J Biol Chem. 2018 Jul 20;293(29):11648. doi: 10.1074/jbc.AAC118.004590. No abstract available.

PMID:
30030383
2.

Basophil-lineage commitment in acute promyelocytic leukemia predicts for severe bleeding after starting therapy.

Matarraz S, Leoz P, Fernández C, Colado E, Chillón MC, Vidriales MB, González M, Rivera D, Osuna CS, Caballero-Velázquez T, Van Der Velden V, Jongen-Lavrencic M, Gutiérrez O, Bermejo AY, Alonso LG, García MB, De Ramón Sánchez C, García-Donas G, Mateo AG, Recio I, Sánchez-Real J, Mayado A, Gutiérrez ML, Bárcena P, Barrena S, López A, Van Dongen J, Orfao A.

Mod Pathol. 2018 Mar 23. doi: 10.1038/s41379-018-0038-2. [Epub ahead of print]

PMID:
29572500
3.

The mutational landscape of small lymphocytic lymphoma compared to non-early stage chronic lymphocytic leukemia.

Martínez-Trillos A, Pinyol M, Delgado J, Aymerich M, Rozman M, Baumann T, González-Díaz M, Hernández JM, Alcoceba M, Muntañola A, Terol MJ, Navarro B, Giné E, Jares P, Beà S, Navarro A, Colomer D, Nadeu F, Colado E, Payer AR, García-Cerecedo T, Puente XS, López-Otin C, Campo E, López-Guillermo A, Villamor N.

Leuk Lymphoma. 2017 Nov 8:1-9. doi: 10.1080/10428194.2017.1397660. [Epub ahead of print]

PMID:
29115891
4.

Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia.

Nadeu F, Clot G, Delgado J, Martín-García D, Baumann T, Salaverria I, Beà S, Pinyol M, Jares P, Navarro A, Suárez-Cisneros H, Aymerich M, Rozman M, Villamor N, Colomer D, González M, Alcoceba M, Terol MJ, Navarro B, Colado E, Payer ÁR, Puente XS, López-Otín C, López-Guillermo A, Enjuanes A, Campo E.

Leukemia. 2018 Mar;32(3):645-653. doi: 10.1038/leu.2017.291. Epub 2017 Sep 19.

5.

The impact of antimicrobial prophylaxis in morbidity and infections during azacitidine treatment.

Lorenzana N, Avila LF, Alonso S, Colado E, Bernal T.

Ann Hematol. 2017 Nov;96(11):1833-1840. doi: 10.1007/s00277-017-3091-x. Epub 2017 Aug 13.

PMID:
28803258
6.

Increasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognition.

Raneros AB, Puras AM, Rodriguez RM, Colado E, Bernal T, Anguita E, Mogorron AV, Gil AC, Vidal-Castiñeira JR, Márquez-Kisinousky L, Bulnes PD, Marin AM, Garay MCG, Suarez-Alvarez B, Lopez-Larrea C.

Oncotarget. 2017 May 9;8(19):31959-31976. doi: 10.18632/oncotarget.16657.

7.

Diagnostic screening of paroxysmal nocturnal hemoglobinuria: Prospective multicentric evaluation of the current medical indications.

Morado M, Freire Sandes A, Colado E, Subirá D, Isusi P, Soledad Noya M, Belén Vidriales M, Sempere A, Ángel Díaz J, Minguela A, Álvarez B, Serrano C, Caballero T, Rey M, Pérez Corral A, Cristina Fernández Jiménez M, Magro E, Lemes A, Benavente C, Bañas H, Merino J, Castejon C, Gutierrez O, Rabasa P, Vescosi Gonçalves M, Perez-Andres M, Orfao A; PNH working group of the Iberian Society of Cytometry (SIC).

Cytometry B Clin Cytom. 2017 Sep;92(5):361-370. doi: 10.1002/cyto.b.21480. Epub 2016 Oct 1.

PMID:
27598686
8.

MMP-25 Metalloprotease Regulates Innate Immune Response through NF-κB Signaling.

Soria-Valles C, Gutiérrez-Fernández A, Osorio FG, Carrero D, Ferrando AA, Colado E, Fernández-García MS, Bonzon-Kulichenko E, Vázquez J, Fueyo A, López-Otín C.

J Immunol. 2016 Jul 1;197(1):296-302. doi: 10.4049/jimmunol.1600094. Epub 2016 Jun 3.

9.

Effects of Estrogen and Phytoestrogen Treatment on an In Vitro Model of Recurrent Stroke on HT22 Neuronal Cell Line.

Morán J, Perez-Basterrechea M, Garrido P, Díaz E, Alonso A, Otero J, Colado E, González C.

Cell Mol Neurobiol. 2017 Apr;37(3):405-416. doi: 10.1007/s10571-016-0372-1. Epub 2016 Apr 8.

PMID:
27059741
10.

[Spanish consensus statement for diagnosis and treatment of paroxysmal nocturnal haemoglobinuria].

Villegas A, Arrizabalaga B, Bonanad S, Colado E, Gaya A, González A, Jarque I, Núñez R, Ojeda E, Orfao A, Ribera JM, Vicente V, Urbano-Ispizua Á; Grupo de Trabajo de HPN de la Sociedad Española de Hematología y Hemoterapia.

Med Clin (Barc). 2016 Mar 18;146(6):278.e1-7. doi: 10.1016/j.medcli.2015.12.012. Epub 2016 Feb 17. Spanish.

PMID:
26895645
11.

Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.

Nadeu F, Delgado J, Royo C, Baumann T, Stankovic T, Pinyol M, Jares P, Navarro A, Martín-García D, Beà S, Salaverria I, Oldreive C, Aymerich M, Suárez-Cisneros H, Rozman M, Villamor N, Colomer D, López-Guillermo A, González M, Alcoceba M, Terol MJ, Colado E, Puente XS, López-Otín C, Enjuanes A, Campo E.

Blood. 2016 Apr 28;127(17):2122-30. doi: 10.1182/blood-2015-07-659144. Epub 2016 Feb 2.

12.

Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.

Osorio FG, Soria-Valles C, Santiago-Fernández O, Bernal T, Mittelbrunn M, Colado E, Rodríguez F, Bonzon-Kulichenko E, Vázquez J, Porta-de-la-Riva M, Cerón J, Fueyo A, Li J, Green AR, Freije JM, López-Otín C.

Nat Med. 2016 Jan;22(1):91-6. doi: 10.1038/nm.4013. Epub 2015 Dec 21.

PMID:
26692333
13.

Non-coding recurrent mutations in chronic lymphocytic leukaemia.

Puente XS, Beà S, Valdés-Mas R, Villamor N, Gutiérrez-Abril J, Martín-Subero JI, Munar M, Rubio-Pérez C, Jares P, Aymerich M, Baumann T, Beekman R, Belver L, Carrio A, Castellano G, Clot G, Colado E, Colomer D, Costa D, Delgado J, Enjuanes A, Estivill X, Ferrando AA, Gelpí JL, González B, González S, González M, Gut M, Hernández-Rivas JM, López-Guerra M, Martín-García D, Navarro A, Nicolás P, Orozco M, Payer ÁR, Pinyol M, Pisano DG, Puente DA, Queirós AC, Quesada V, Romeo-Casabona CM, Royo C, Royo R, Rozman M, Russiñol N, Salaverría I, Stamatopoulos K, Stunnenberg HG, Tamborero D, Terol MJ, Valencia A, López-Bigas N, Torrents D, Gut I, López-Guillermo A, López-Otín C, Campo E.

Nature. 2015 Oct 22;526(7574):519-24. doi: 10.1038/nature14666. Epub 2015 Jul 22.

PMID:
26200345
14.

Genomic complexity and IGHV mutational status are key predictors of outcome of chronic lymphocytic leukemia patients with TP53 disruption.

Delgado J, Salaverria I, Baumann T, Martínez-Trillos A, Lee E, Jiménez L, Navarro A, Royo C, Santacruz R, López C, Payer AR, Colado E, González M, Armengol L, Colomer D, Pinyol M, Villamor N, Aymerich M, Carrió A, Costa D, Clot G, Giné E, López-Guillermo A, Campo E, Beà S.

Haematologica. 2014 Nov;99(11):e231-4. doi: 10.3324/haematol.2014.108365. Epub 2014 Jul 4. No abstract available.

15.

Multiparameter flow cytometry for staging of solitary bone plasmacytoma: new criteria for risk of progression to myeloma.

Paiva B, Chandia M, Vidriales MB, Colado E, Caballero-Velázquez T, Escalante F, Garcia de Coca A, Montes MC, Garcia-Sanz R, Ocio EM, Mateos MV, San Miguel JF.

Blood. 2014 Aug 21;124(8):1300-3. doi: 10.1182/blood-2014-04-567909. Epub 2014 May 29.

16.

Mutations in TLR/MYD88 pathway identify a subset of young chronic lymphocytic leukemia patients with favorable outcome.

Martínez-Trillos A, Pinyol M, Navarro A, Aymerich M, Jares P, Juan M, Rozman M, Colomer D, Delgado J, Giné E, González-Díaz M, Hernández-Rivas JM, Colado E, Rayón C, Payer AR, Terol MJ, Navarro B, Quesada V, Puente XS, Rozman C, López-Otín C, Campo E, López-Guillermo A, Villamor N.

Blood. 2014 Jun 12;123(24):3790-6. doi: 10.1182/blood-2013-12-543306. Epub 2014 Apr 29.

17.

Role of minimal residual disease and chimerism after reduced-intensity and myeloablative allo-transplantation in acute myeloid leukemia and high-risk myelodysplastic syndrome.

Bernal T, Diez-Campelo M, Godoy V, Rojas S, Colado E, Alcoceba M, González M, Vidriales B, Sánchez-Guijo FM, López-Corral L, Luño E, del Cañizo C.

Leuk Res. 2014 May;38(5):551-6. doi: 10.1016/j.leukres.2014.02.001. Epub 2014 Feb 10.

PMID:
24655806
18.

Hairy cell leukemia treated initially with purine analogs: a retrospective study of 107 patients from the Spanish Cooperative Group on Chronic Lymphocytic Leukemia (GELLC).

López Rubio M, Da Silva C, Loscertales J, Seri C, Baltasar P, Colado E, Pérez Fernández I, Osma M, Gomis F, González M, Jarque I, Vargas M, Monzó E, Monteagudo D, Orts MI, Pardal E, Carbonell F, Perez Calvo C, Garcia-Marco JA.

Leuk Lymphoma. 2014 May;55(5):1007-12. doi: 10.3109/10428194.2013.827187. Epub 2013 Sep 16.

PMID:
23885799
19.

Newly diagnosed adult AML and MPAL patients frequently show clonal residual hematopoiesis.

Fernandez C, Santos-Silva MC, López A, Matarraz S, Jara-Acevedo M, Ciudad J, Gutierrez ML, Sánchez ML, Salvador-Osuna C, Berruezo MJ, Díaz-Arias JÁ, Palomo-Hernández AM, Colado E, González N, Gallardo D, Asensio A, García-Sánchez R, Saldaña R, Cerveró C, Carboné-Bañeres A, Gutierrez O, Orfao A.

Leukemia. 2013 Nov;27(11):2149-56. doi: 10.1038/leu.2013.109. Epub 2013 Apr 12.

PMID:
23579575
20.

DNA methylation dynamics in blood after hematopoietic cell transplant.

Rodriguez RM, Suarez-Alvarez B, Salvanés R, Muro M, Martínez-Camblor P, Colado E, Sánchez MA, Díaz MG, Fernandez AF, Fraga MF, Lopez-Larrea C.

PLoS One. 2013;8(2):e56931. doi: 10.1371/journal.pone.0056931. Epub 2013 Feb 22. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/2f9880f8-6b33-4b78-9914-d1129a5af8cd.

21.

NOTCH1 mutations identify a genetic subgroup of chronic lymphocytic leukemia patients with high risk of transformation and poor outcome.

Villamor N, Conde L, Martínez-Trillos A, Cazorla M, Navarro A, Beà S, López C, Colomer D, Pinyol M, Aymerich M, Rozman M, Abrisqueta P, Baumann T, Delgado J, Giné E, González-Díaz M, Hernández JM, Colado E, Payer AR, Rayon C, Navarro B, José Terol M, Bosch F, Quesada V, Puente XS, López-Otín C, Jares P, Pereira A, Campo E, López-Guillermo A.

Leukemia. 2013 Apr;27(5):1100-6. doi: 10.1038/leu.2012.357. Epub 2012 Dec 6.

PMID:
23295735
22.

ADAMTS-12 metalloprotease is necessary for normal inflammatory response.

Moncada-Pazos A, Obaya AJ, Llamazares M, Heljasvaara R, Suárez MF, Colado E, Noël A, Cal S, López-Otín C.

J Biol Chem. 2012 Nov 16;287(47):39554-63. doi: 10.1074/jbc.M112.408625. Epub 2012 Sep 27. Erratum in: J Biol Chem. 2018 Jul 20;293(29):11648.

23.

MMP-8 deficiency increases TLR/RAGE ligands S100A8 and S100A9 and exacerbates lung inflammation during endotoxemia.

González-López A, Aguirre A, López-Alonso I, Amado L, Astudillo A, Fernández-García MS, Suárez MF, Batalla-Solís E, Colado E, Albaiceta GM.

PLoS One. 2012;7(6):e39940. doi: 10.1371/journal.pone.0039940. Epub 2012 Jun 29.

24.

Transcriptomic rationale for the synergy observed with dasatinib + bortezomib + dexamethasone in multiple myeloma.

de Queiroz Crusoe E, Maiso P, Fernandez-Lazaro D, San-Segundo L, Garayoa M, Garcia-Gomez A, Gutierrez NC, Delgado M, Colado E, Martin-Sanchez J, Lee FY, Ocio EM.

Ann Hematol. 2012 Feb;91(2):257-69. doi: 10.1007/s00277-011-1287-z. Epub 2011 Jul 1.

PMID:
21720745
25.

Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response.

Colado E, Paíno T, Maiso P, Ocio EM, Chen X, Alvarez-Fernández S, Gutiérrez NC, Martín-Sánchez J, Flores-Montero J, San Segundo L, Garayoa M, Fernández-Lázaro D, Vidriales MB, Galmarini CM, Avilés P, Cuevas C, Pandiella A, San-Miguel JF.

Haematologica. 2011 May;96(5):687-95. doi: 10.3324/haematol.2010.036400. Epub 2011 Feb 17.

26.

[Diagnosis and treatment of nocturnal paroxysmal hemoglobinuria].

Urbano-Ispizua A, Gaya A, Colado E, López M, Arrizabalaga B, Vicente V, Orfao A, Villegas A, Vallejo C.

Med Clin (Barc). 2011 Feb 12;136(3):121-7. doi: 10.1016/j.medcli.2010.07.017. Epub 2010 Nov 13. Spanish. No abstract available.

PMID:
21075403
27.

Liver function tests and absolute lymphocyte count at day +100 are predictive factors for extensive and severe chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplant.

Silva F, Pérez-Simón JA, Caballero Velazquez T, Encinas C, Sánchez-Guijo FM, Díez-Campelo M, Colado E, Martín J, Villanueva-Gomez F, Vazquez L, Del Cañizo C, Caballero D, San Miguel J.

Am J Hematol. 2010 Apr;85(4):290-3. doi: 10.1002/ajh.21613. No abstract available.

28.

The synergy of panobinostat plus doxorubicin in acute myeloid leukemia suggests a role for HDAC inhibitors in the control of DNA repair.

Maiso P, Colado E, Ocio EM, Garayoa M, Martín J, Atadja P, Pandiella A, San-Miguel JF.

Leukemia. 2009 Dec;23(12):2265-74. doi: 10.1038/leu.2009.182. Epub 2009 Oct 8.

PMID:
19812608
29.

An individualized pre-operative blood saving protocol can increase pre-operative haemoglobin levels and reduce the need for transfusion in elective total hip or knee arthroplasty.

Gonzalez-Porras JR, Colado E, Conde MP, Lopez T, Nieto MJ, Corral M.

Transfus Med. 2009 Feb;19(1):35-42. doi: 10.1111/j.1365-3148.2009.00908.x.

PMID:
19302453
30.

Prognostic factors of chronic graft-versus-host disease following allogeneic peripheral blood stem cell transplantation: the national institutes health scale plus the type of onset can predict survival rates and the duration of immunosuppressive therapy.

Pérez-Simón JA, Encinas C, Silva F, Arcos MJ, Díez-Campelo M, Sánchez-Guijo FM, Colado E, Martín J, Vazquez L, Del Cañizo C, Caballero D, San Miguel J.

Biol Blood Marrow Transplant. 2008 Oct;14(10):1163-1171. doi: 10.1016/j.bbmt.2008.07.015.

31.

The effect of the proteasome inhibitor bortezomib on acute myeloid leukemia cells and drug resistance associated with the CD34+ immature phenotype.

Colado E, Alvarez-Fernández S, Maiso P, Martín-Sánchez J, Vidriales MB, Garayoa M, Ocio EM, Montero JC, Pandiella A, San Miguel JF.

Haematologica. 2008 Jan;93(1):57-66. doi: 10.3324/haematol.11666.

32.

Should prophylactic granulocyte-colony stimulating factor be used in multiple myeloma patients developing neutropenia under lenalidomide-based therapy?

Mateos MV, García-Sanz R, Colado E, Olazábal J, San-Miguel J.

Br J Haematol. 2008 Feb;140(3):324-6. Epub 2007 Dec 7.

PMID:
18067473

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