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Items: 1 to 50 of 94

1.

Mechanistic convergence and shared therapeutic targets in Niemann-Pick disease.

Colaco A, Kaya E, Adriaenssens E, Davis LC, Zampieri S, Fernández-Suárez ME, Tan CY, Deegan PB, Porter FD, Galione A, Bembi B, Dardis A, Platt FM.

J Inherit Metab Dis. 2019 Nov 9. doi: 10.1002/jimd.12191. [Epub ahead of print]

PMID:
31707734
2.

Removal of deep-sea sponges by bottom trawling in the Flemish Cap area: conservation, ecology and economic assessment.

Pham CK, Murillo FJ, Lirette C, Maldonado M, Colaço A, Ottaviani D, Kenchington E.

Sci Rep. 2019 Nov 1;9(1):15843. doi: 10.1038/s41598-019-52250-1.

3.

Dietary Supplementation with the Red Seaweed Porphyra umbilicalis Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice.

Santos S, Ferreira T, Almeida J, Pires MJ, Colaço A, Lemos S, Gil da Costa RM, Medeiros R, Bastos MMSM, Neuparth MJ, Abreu H, Pereira R, Pacheco M, Gaivão I, Rosa E, Oliveira PA.

Mar Drugs. 2019 Oct 29;17(11). pii: E615. doi: 10.3390/md17110615.

4.

Stable isotopes reveal winter feeding in different habitats in blue, fin and sei whales migrating through the Azores.

Silva MA, Borrell A, Prieto R, Gauffier P, Bérubé M, Palsbøl PJ, Colaço A.

R Soc Open Sci. 2019 Aug 14;6(8):181800. doi: 10.1098/rsos.181800. eCollection 2019 Aug.

5.

NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress.

Höglinger D, Burgoyne T, Sanchez-Heras E, Hartwig P, Colaco A, Newton J, Futter CE, Spiegel S, Platt FM, Eden ER.

Nat Commun. 2019 Sep 19;10(1):4276. doi: 10.1038/s41467-019-12152-2.

6.

Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice.

Moreau D, Vacca F, Vossio S, Scott C, Colaco A, Paz Montoya J, Ferguson C, Damme M, Moniatte M, Parton RG, Platt FM, Gruenberg J.

EMBO Rep. 2019 Jul;20(7):e47055. doi: 10.15252/embr.201847055. Epub 2019 May 22.

7.

Reference intervals for haematological parameters in the Lusitano horse breed.

Silvestre-Ferreira AC, Cotovio M, Maia M, Queiroga F, Pires MJ, Colaço A.

Acta Vet Hung. 2018 Dec;66(4):530-541. doi: 10.1556/004.2018.047.

PMID:
30580541
8.

STAT3 associates with vacuolar H+-ATPase and regulates cytosolic and lysosomal pH.

Liu B, Palmfeldt J, Lin L, Colaço A, Clemmensen KKB, Huang J, Xu F, Liu X, Maeda K, Luo Y, Jäättelä M.

Cell Res. 2018 Oct;28(10):996-1012. doi: 10.1038/s41422-018-0080-0. Epub 2018 Aug 20.

9.

A strategy for the conservation of biodiversity on mid-ocean ridges from deep-sea mining.

Dunn DC, Van Dover CL, Etter RJ, Smith CR, Levin LA, Morato T, Colaço A, Dale AC, Gebruk AV, Gjerde KM, Halpin PN, Howell KL, Johnson D, Perez JAA, Ribeiro MC, Stuckas H, Weaver P; SEMPIA Workshop Participants.

Sci Adv. 2018 Jul 4;4(7):eaar4313. doi: 10.1126/sciadv.aar4313. eCollection 2018 Jul.

10.

Application of light detection and ranging and ultrasonic sensors to high-throughput phenotyping and precision horticulture: current status and challenges.

Colaço AF, Molin JP, Rosell-Polo JR, Escolà A.

Hortic Res. 2018 Jul 1;5:35. doi: 10.1038/s41438-018-0043-0. eCollection 2018.

11.

AAV9 intracerebroventricular gene therapy improves lifespan, locomotor function and pathology in a mouse model of Niemann-Pick type C1 disease.

Hughes MP, Smith DA, Morris L, Fletcher C, Colaco A, Huebecker M, Tordo J, Palomar N, Massaro G, Henckaerts E, Waddington SN, Platt FM, Rahim AA.

Hum Mol Genet. 2018 Sep 1;27(17):3079-3098. doi: 10.1093/hmg/ddy212.

12.

Metal interactions between the polychaete Branchipolynoe seepensis and the mussel Bathymodiolus azoricus from Mid-Atlantic-Ridge hydrothermal vent fields.

Bebianno MJ, Cardoso C, Gomes T, Blasco J, Santos RS, Colaço A.

Mar Environ Res. 2018 Apr;135:70-81. doi: 10.1016/j.marenvres.2018.01.017. Epub 2018 Jan 31.

PMID:
29402519
13.

A global perspective on the trophic geography of sharks.

Bird CS, Veríssimo A, Magozzi S, Abrantes KG, Aguilar A, Al-Reasi H, Barnett A, Bethea DM, Biais G, Borrell A, Bouchoucha M, Boyle M, Brooks EJ, Brunnschweiler J, Bustamante P, Carlisle A, Catarino D, Caut S, Cherel Y, Chouvelon T, Churchill D, Ciancio J, Claes J, Colaço A, Courtney DL, Cresson P, Daly R, de Necker L, Endo T, Figueiredo I, Frisch AJ, Hansen JH, Heithaus M, Hussey NE, Iitembu J, Juanes F, Kinney MJ, Kiszka JJ, Klarian SA, Kopp D, Leaf R, Li Y, Lorrain A, Madigan DJ, Maljković A, Malpica-Cruz L, Matich P, Meekan MG, Ménard F, Menezes GM, Munroe SEM, Newman MC, Papastamatiou YP, Pethybridge H, Plumlee JD, Polo-Silva C, Quaeck-Davies K, Raoult V, Reum J, Torres-Rojas YE, Shiffman DS, Shipley ON, Speed CW, Staudinger MD, Teffer AK, Tilley A, Valls M, Vaudo JJ, Wai TC, Wells RJD, Wyatt ASJ, Yool A, Trueman CN.

Nat Ecol Evol. 2018 Feb;2(2):299-305. doi: 10.1038/s41559-017-0432-z. Epub 2018 Jan 18.

14.

Ragulator-a multifaceted regulator of lysosomal signaling and trafficking.

Colaço A, Jäättelä M.

J Cell Biol. 2017 Dec 4;216(12):3895-3898. doi: 10.1083/jcb.201710039. Epub 2017 Nov 14.

15.

Physiological impacts of acute Cu exposure on deep-sea vent mussel Bathymodiolus azoricus under a deep-sea mining activity scenario.

Martins I, Goulart J, Martins E, Morales-Román R, Marín S, Riou V, Colaço A, Bettencourt R.

Aquat Toxicol. 2017 Dec;193:40-49. doi: 10.1016/j.aquatox.2017.10.004. Epub 2017 Oct 9.

PMID:
29032352
16.

Long-term treatment with chaethomellic acid A reduces glomerulosclerosis and arteriolosclerosis in a rat model of chronic kidney disease.

Nogueira A, Vala H, Vasconcelos-Nóbrega C, Faustino-Rocha AI, Pires CA, Colaço A, Oliveira PA, Pires MJ.

Biomed Pharmacother. 2017 Dec;96:489-496. doi: 10.1016/j.biopha.2017.09.137. Epub 2017 Oct 12.

PMID:
29032332
17.

Chemical Editing of Macrocyclic Natural Products and Kinetic Profiling Reveal Slow, Tight-Binding Histone Deacetylase Inhibitors with Picomolar Affinities.

Kitir B, Maolanon AR, Ohm RG, Colaço AR, Fristrup P, Madsen AS, Olsen CA.

Biochemistry. 2017 Sep 26;56(38):5134-5146. doi: 10.1021/acs.biochem.7b00725. Epub 2017 Sep 15.

PMID:
28858522
18.

Resilience of benthic deep-sea fauna to mining activities.

Gollner S, Kaiser S, Menzel L, Jones DOB, Brown A, Mestre NC, van Oevelen D, Menot L, Colaço A, Canals M, Cuvelier D, Durden JM, Gebruk A, Egho GA, Haeckel M, Marcon Y, Mevenkamp L, Morato T, Pham CK, Purser A, Sanchez-Vidal A, Vanreusel A, Vink A, Martinez Arbizu P.

Mar Environ Res. 2017 Aug;129:76-101. doi: 10.1016/j.marenvres.2017.04.010. Epub 2017 Apr 13. Review.

PMID:
28487161
19.

Animal models as a tool in hepatocellular carcinoma research: A Review.

Santos NP, Colaço AA, Oliveira PA.

Tumour Biol. 2017 Mar;39(3):1010428317695923. doi: 10.1177/1010428317695923.

PMID:
28347231
20.

FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.

Newton J, Hait NC, Maceyka M, Colaco A, Maczis M, Wassif CA, Cougnoux A, Porter FD, Milstien S, Platt N, Platt FM, Spiegel S.

FASEB J. 2017 Apr;31(4):1719-1730. doi: 10.1096/fj.201601041R. Epub 2017 Jan 12.

21.

Topical Therapy With Imiquimod for Vaginal Intraepithelial Neoplasia: A Case Series.

Policiano AC, Lopes JP, Barata SA, Colaço AM, Calhaz-Jorge C.

J Low Genit Tract Dis. 2016 Jul;20(3):e34-6. doi: 10.1097/LGT.0000000000000214. No abstract available.

PMID:
27158879
22.

Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH.

Madsen AS, Andersen C, Daoud M, Anderson KA, Laursen JS, Chakladar S, Huynh FK, Colaço AR, Backos DS, Fristrup P, Hirschey MD, Olsen CA.

J Biol Chem. 2016 Mar 25;291(13):7128-41. doi: 10.1074/jbc.M115.668699. Epub 2016 Feb 9.

23.

A comparative study on fluorescent cholesterol analogs as versatile cellular reporters.

Sezgin E, Can FB, Schneider F, Clausen MP, Galiani S, Stanly TA, Waithe D, Colaco A, Honigmann A, Wüstner D, Platt F, Eggeling C.

J Lipid Res. 2016 Feb;57(2):299-309. doi: 10.1194/jlr.M065326. Epub 2015 Dec 23.

24.

Altered expression of CKs 14/20 is an early event in a rat model of multistep bladder carcinogenesis.

Gil da Costa RM, Oliveira PA, Vasconcelos-Nóbrega C, Arantes-Rodrigues R, Pinto-Leite R, Colaço AA, de la Cruz LF, Lopes C.

Int J Exp Pathol. 2015 Oct;96(5):319-25. doi: 10.1111/iep.12145. Epub 2015 Oct 30.

25.

Citreicella manganoxidans sp. nov., a novel manganese oxidizing bacterium isolated from a shallow water hydrothermal vent in Espalamaca (Azores).

Rajasabapathy R, Mohandass C, Dastager SG, Liu Q, Li WJ, Colaço A.

Antonie Van Leeuwenhoek. 2015 Dec;108(6):1433-1439. doi: 10.1007/s10482-015-0597-x. Epub 2015 Sep 24.

PMID:
26404429
26.

Comparative Evaluation of the Efficiency of Manual and Rotary Gutta-percha Removal Techniques.

Colaco AS, Pai VA.

J Endod. 2015 Nov;41(11):1871-4. doi: 10.1016/j.joen.2015.07.012. Epub 2015 Sep 9.

PMID:
26364003
27.

Immune dysfunction in Niemann-Pick disease type C.

Platt N, Speak AO, Colaco A, Gray J, Smith DA, Williams IM, Wallom KL, Platt FM.

J Neurochem. 2016 Jan;136 Suppl 1:74-80. doi: 10.1111/jnc.13138. Epub 2015 Jun 4. Review.

28.

Trihalomethanes in liver pathology: Mitochondrial dysfunction and oxidative stress in the mouse.

Faustino-Rocha AI, Rodrigues D, da Costa RG, Diniz C, Aragão S, Talhada D, Botelho M, Colaço A, Pires MJ, Peixoto F, Oliveira PA.

Environ Toxicol. 2016 Aug;31(8):1009-16. doi: 10.1002/tox.22110. Epub 2015 Jan 9.

PMID:
25640707
29.

The N-nitrosodiethylamine mouse model: sketching a timeline of evolution of chemically-induced hepatic lesions.

Da Costa RM, Paula-Santos N, Rocha AF, Colaço A, Lopes C, Oliveira PA.

Anticancer Res. 2014 Dec;34(12):7029-37.

PMID:
25503129
30.

Nioella nitratireducens gen. nov., sp. nov., a novel member of the family Rhodobacteraceae isolated from Azorean Island.

Rajasabapathy R, Mohandass C, Yoon JH, Dastager SG, Liu Q, Khieu TN, Son CK, Li WJ, Colaco A.

Antonie Van Leeuwenhoek. 2015 Feb;107(2):589-95. doi: 10.1007/s10482-014-0355-5. Epub 2014 Dec 14.

PMID:
25500750
31.

[Nursing intervention bundle for enteral nutrition in intensive care: a collective construction].

Colaço AD, Nascimento ER.

Rev Esc Enferm USP. 2014 Oct;48(5):844-50. Portuguese.

32.

Is the deep-sea crab Chaceon affinis able to induce a thermal stress response?

Mestre NC, Cottin D, Bettencourt R, Colaço A, Correia SP, Shillito B, Thatje S, Ravaux J.

Comp Biochem Physiol A Mol Integr Physiol. 2015 Mar;181:54-61. doi: 10.1016/j.cbpa.2014.11.015. Epub 2014 Nov 26.

PMID:
25434602
33.

Vitellibacter nionensis sp. nov., isolated from a shallow water hydrothermal vent.

Rajasabapathy R, Mohandass C, Yoon JH, Dastager SG, Liu Q, Khieu TN, Son CK, Li WJ, Colaço A.

Int J Syst Evol Microbiol. 2015 Feb;65(Pt 2):692-7. doi: 10.1099/ijs.0.070805-0. Epub 2014 Nov 26.

PMID:
25428420
34.

Biomarkers for disease progression and AAV therapeutic efficacy in feline Sandhoff disease.

Bradbury AM, Gray-Edwards HL, Shirley JL, McCurdy VJ, Colaco AN, Randle AN, Christopherson PW, Bird AC, Johnson AK, Wilson DU, Hudson JA, De Pompa NL, Sorjonen DC, Brunson BL, Jeyakumar M, Platt FM, Baker HJ, Cox NR, Sena-Esteves M, Martin DR.

Exp Neurol. 2015 Jan;263:102-12. doi: 10.1016/j.expneurol.2014.09.020. Epub 2014 Oct 5.

35.

Disorders of cholesterol metabolism and their unanticipated convergent mechanisms of disease.

Platt FM, Wassif C, Colaco A, Dardis A, Lloyd-Evans E, Bembi B, Porter FD.

Annu Rev Genomics Hum Genet. 2014;15:173-94. doi: 10.1146/annurev-genom-091212-153412.

36.

N-diethylnitrosamine mouse hepatotoxicity: time-related effects on histology and oxidative stress.

Paula Santos N, Colaço A, Gil da Costa RM, Manuel Oliveira M, Peixoto F, Alexandra Oliveira P.

Exp Toxicol Pathol. 2014 Dec;66(9-10):429-36. doi: 10.1016/j.etp.2014.07.002. Epub 2014 Aug 2.

PMID:
25097018
37.

Biomonitoring of heavy metals (Cd, Hg, and Pb) and metalloid (As) with the Portuguese common buzzard (Buteo buteo).

Carneiro M, Colaço B, Brandão R, Ferreira C, Santos N, Soeiro V, Colaço A, Pires MJ, Oliveira PA, Lavín S.

Environ Monit Assess. 2014 Nov;186(11):7011-21. doi: 10.1007/s10661-014-3906-3. Epub 2014 Jul 30.

PMID:
25074364
38.

Halide selective anion recognition by an amide-triazolium axle containing [2]rotaxane.

White NG, Colaço AR, Marques I, Félix V, Beer PD.

Org Biomol Chem. 2014 Jul 21;12(27):4924-31. doi: 10.1039/c4ob00801d.

PMID:
24876069
39.

Cytokeratin 7/19 expression in N-diethylnitrosamine-induced mouse hepatocellular lesions: implications for histogenesis.

Santos NP, Oliveira PA, Arantes-Rodrigues R, Faustino-Rocha AI, Colaço A, Lopes C, Gil da Costa RM.

Int J Exp Pathol. 2014 Jun;95(3):191-8. doi: 10.1111/iep.12082. Epub 2014 Apr 15.

40.

Tris-thiourea tripodal-based molecules as chloride transmembrane transporters: insights from molecular dynamics simulations.

Marques I, Colaço AR, Costa PJ, Busschaert N, Gale PA, Félix V.

Soft Matter. 2014 May 28;10(20):3608-21. doi: 10.1039/c3sm52140k. Epub 2014 Mar 24.

PMID:
24663079
41.

Roseovarius azorensis sp. nov., isolated from seawater at Espalamaca, Azores.

Rajasabapathy R, Mohandass C, Dastager SG, Liu Q, Khieu TN, Son CK, Li WJ, Colaco A.

Antonie Van Leeuwenhoek. 2014 Mar;105(3):571-8. doi: 10.1007/s10482-013-0109-9. Epub 2014 Jan 3.

PMID:
24384627
42.

Synergistic effect between cisplatin and sunitinib malate on human urinary bladder-cancer cell lines.

Arantes-Rodrigues R, Pinto-Leite R, Fidalgo-Gonçalves L, Palmeira C, Santos L, Colaço A, Oliveira P.

Biomed Res Int. 2013;2013:791406. doi: 10.1155/2013/791406. Epub 2013 Nov 28.

43.

First-photon imaging.

Kirmani A, Venkatraman D, Shin D, Colaço A, Wong FN, Shapiro JH, Goyal VK.

Science. 2014 Jan 3;343(6166):58-61. doi: 10.1126/science.1246775. Epub 2013 Nov 29.

PMID:
24292628
44.

Temsirolimus improves cytotoxic efficacy of cisplatin and gemcitabine against urinary bladder cancer cell lines.

Pinto-Leite R, Arantes-Rodrigues R, Ferreira R, Palmeira C, Colaço A, Moreira da Silva V, Oliveira P, Lara Santos L.

Urol Oncol. 2014 Jan;32(1):41.e11-22. doi: 10.1016/j.urolonc.2013.04.012. Epub 2013 Sep 10.

PMID:
24035472
45.

Effects of nebivolol on liver fibrosis induced by bile duct ligation in Wistar rats.

Teixeira C, Franco E, Oliveira PA, Colaço B, Gama A, Carrola J, Pires CA, Colaço A, Pires MJ.

In Vivo. 2013 Sep-Oct;27(5):635-40.

PMID:
23988899
46.

Cytogenetic characterization of an N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse papillary urothelial carcinoma.

Arantes-Rodrigues R, Pinto-Leite R, da Costa RG, Colaço A, Lopes C, Oliveira P.

Tumour Biol. 2013 Oct;34(5):2691-6. doi: 10.1007/s13277-013-0820-1. Epub 2013 May 5.

PMID:
23645214
47.

Meloxicam in the treatment of in vitro and in vivo models of urinary bladder cancer.

Arantes-Rodrigues R, Pinto-Leite R, Ferreira R, Neuparth MJ, Pires MJ, Gaivão I, Palmeira C, Santos L, Colaço A, Oliveira P.

Biomed Pharmacother. 2013 May;67(4):277-84. doi: 10.1016/j.biopha.2013.01.010. Epub 2013 Feb 18.

PMID:
23582791
48.

In vitro and in vivo experimental models as tools to investigate the efficacy of antineoplastic drugs on urinary bladder cancer.

Arantes-Rodrigues R, Colaço A, Pinto-Leite R, Oliveira PA.

Anticancer Res. 2013 Apr;33(4):1273-96. Review.

PMID:
23564765
49.

E-cadherin and β-catenin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in mice.

Vasconcelos-Nóbrega C, Costa C, Vala H, Colaço A, Santos L, Lopes C, Oliveira PA.

Urol Int. 2013;91(4):462-6. doi: 10.1159/000348329. Epub 2013 Mar 20.

PMID:
23548313
50.

Everolimus combined with cisplatin has a potential role in treatment of urothelial bladder cancer.

Pinto-Leite R, Arantes-Rodrigues R, Palmeira C, Colaço B, Lopes C, Colaço A, Costa C, da Silva VM, Oliveira P, Santos L.

Biomed Pharmacother. 2013 Mar;67(2):116-21. doi: 10.1016/j.biopha.2012.11.007. Epub 2012 Dec 26.

PMID:
23433853

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