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Items: 7


Differences in Signaling Patterns on PI3K Inhibition Reveal Context Specificity in KRAS-Mutant Cancers.

Stewart A, Coker EA, Pölsterl S, Georgiou A, Minchom AR, Carreira S, Cunningham D, O'Brien ME, Raynaud FI, de Bono JS, Al-Lazikani B, Banerji U.

Mol Cancer Ther. 2019 Aug;18(8):1396-1404. doi: 10.1158/1535-7163.MCT-18-0727. Epub 2019 Jul 1.


Leveraging Human Genetics to Guide Cancer Drug Development.

Kinnersley B, Sud A, Coker EA, Tym JE, Di Micco P, Al-Lazikani B, Houlston RS.

JCO Clin Cancer Inform. 2018 Dec;2:1-11. doi: 10.1200/CCI.18.00077.


canSAR: update to the cancer translational research and drug discovery knowledgebase.

Coker EA, Mitsopoulos C, Tym JE, Komianou A, Kannas C, Di Micco P, Villasclaras Fernandez E, Ozer B, Antolin AA, Workman P, Al-Lazikani B.

Nucleic Acids Res. 2019 Jan 8;47(D1):D917-D922. doi: 10.1093/nar/gky1129.


Simulated ablation for detection of cells impacting paracrine signalling in histology analysis.

Taylor-King JP, Baratchart E, Dhawan A, Coker EA, Rye IH, Russnes H, Chapman SJ, Basanta D, Marusyk A.

Math Med Biol. 2019 Mar 14;36(1):93-112. doi: 10.1093/imammb/dqx022.


SiGNet: A signaling network data simulator to enable signaling network inference.

Coker EA, Mitsopoulos C, Workman P, Al-Lazikani B.

PLoS One. 2017 May 17;12(5):e0177701. doi: 10.1371/journal.pone.0177701. eCollection 2017.


canSAR: an updated cancer research and drug discovery knowledgebase.

Tym JE, Mitsopoulos C, Coker EA, Razaz P, Schierz AC, Antolin AA, Al-Lazikani B.

Nucleic Acids Res. 2016 Jan 4;44(D1):D938-43. doi: 10.1093/nar/gkv1030. Epub 2015 Dec 15.


canSAR: updated cancer research and drug discovery knowledgebase.

Bulusu KC, Tym JE, Coker EA, Schierz AC, Al-Lazikani B.

Nucleic Acids Res. 2014 Jan;42(Database issue):D1040-7. doi: 10.1093/nar/gkt1182. Epub 2013 Dec 3.

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