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Items: 24


Crystal structure of zinc-α2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding.

Lau AM, Zahid H, Gor J, Perkins SJ, Coker AR, McDermott LC.

Biochem J. 2019 Oct 15;476(19):2815-2834. doi: 10.1042/BCJ20190354.


Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening.

Resnick E, Bradley A, Gan J, Douangamath A, Krojer T, Sethi R, Geurink PP, Aimon A, Amitai G, Bellini D, Bennett J, Fairhead M, Fedorov O, Gabizon R, Gan J, Guo J, Plotnikov A, Reznik N, Ruda GF, Díaz-Sáez L, Straub VM, Szommer T, Velupillai S, Zaidman D, Zhang Y, Coker AR, Dowson CG, Barr HM, Wang C, Huber KVM, Brennan PE, Ovaa H, von Delft F, London N.

J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.


Structure and function of the type III pullulan hydrolase from Thermococcus kodakarensis.

Guo J, Coker AR, Wood SP, Cooper JB, Keegan RM, Ahmad N, Muhammad MA, Rashid N, Akhtar M.

Acta Crystallogr D Struct Biol. 2018 Apr 1;74(Pt 4):305-314. doi: 10.1107/S2059798318001754. Epub 2018 Apr 3.


Structure and function of the thermostable L-asparaginase from Thermococcus kodakarensis.

Guo J, Coker AR, Wood SP, Cooper JB, Chohan SM, Rashid N, Akhtar M.

Acta Crystallogr D Struct Biol. 2017 Nov 1;73(Pt 11):889-895. doi: 10.1107/S2059798317014711. Epub 2017 Oct 20.


Structural studies of domain movement in active-site mutants of porphobilinogen deaminase from Bacillus megaterium.

Guo J, Erskine P, Coker AR, Wood SP, Cooper JB.

Acta Crystallogr F Struct Biol Commun. 2017 Nov 1;73(Pt 11):612-620. doi: 10.1107/S2053230X17015436. Epub 2017 Oct 30.


Frutapin, a lectin from Artocarpus incisa (breadfruit): cloning, expression and molecular insights.

de Sousa FD, da Silva BB, Furtado GP, Carneiro IS, Lobo MDP, Guan Y, Guo J, Coker AR, Lourenzoni MR, Guedes MIF, Owen JS, Abraham DJ, Monteiro-Moreira ACO, Moreira RA.

Biosci Rep. 2017 Jul 21;37(4). pii: BSR20170969. doi: 10.1042/BSR20170969. Print 2017 Aug 31.


Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis.

Guo J, Zhang W, Coker AR, Wood SP, Cooper JB, Ahmad S, Ali S, Rashid N, Akhtar M.

Acta Crystallogr D Struct Biol. 2017 May 1;73(Pt 5):420-427. doi: 10.1107/S2059798317004090. Epub 2017 Apr 26.


The 1.1 Å resolution structure of a periplasmic phosphate-binding protein from Stenotrophomonas maltophilia: a crystallization contaminant identified by molecular replacement using the entire Protein Data Bank.

Keegan R, Waterman DG, Hopper DJ, Coates L, Taylor G, Guo J, Coker AR, Erskine PT, Wood SP, Cooper JB.

Acta Crystallogr D Struct Biol. 2016 Aug;72(Pt 8):933-43. doi: 10.1107/S2059798316010433. Epub 2016 Jul 27.


Binding of Gd(3+) to the neuronal signalling protein calexcitin identifies an exchangeable Ca(2+)-binding site.

Chataigner L, Guo J, Erskine PT, Coker AR, Wood SP, Gombos Z, Cooper JB.

Acta Crystallogr F Struct Biol Commun. 2016 Apr;72(Pt 4):276-81. doi: 10.1107/S2053230X16003526. Epub 2016 Mar 16.


Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis.

Warne J, Pryce G, Hill JM, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AW, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL.

J Biol Chem. 2016 Feb 26;291(9):4356-73. doi: 10.1074/jbc.M115.700385. Epub 2015 Dec 17.


Structure of a Kunitz-type potato cathepsin D inhibitor.

Guo J, Erskine PT, Coker AR, Wood SP, Cooper JB.

J Struct Biol. 2015 Dec;192(3):554-560. doi: 10.1016/j.jsb.2015.10.020. Epub 2015 Nov 2. Erratum in: J Struct Biol. 2016 Feb;193(2):155. Mareš, Michael [added]; Baudyš, Miroslav [added].


Extension of resolution and oligomerization-state studies of 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. 4HAP.

Guo J, Erskine P, Coker AR, Gor J, Perkins SJ, Wood SP, Cooper JB.

Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1258-63. doi: 10.1107/S2053230X15015873. Epub 2015 Sep 23.


Dengue virus serotype-2 impairs proliferation of healthy donors' T lymphocytes.

Fuentes-Miranda CJ, Sánchez-García FJ, Coker AR, Rojas-Espinosa O, Salinas-Tobón R, Moreno-Altamirano MM.

Intervirology. 2014;57(2):83-92. doi: 10.1159/000357180. Epub 2014 Jan 28.


Intra-VTA deltorphin, but not DPDPE, induces place preference in ethanol-drinking rats: distinct DOR-1 and DOR-2 mechanisms control ethanol consumption and reward.

Mitchell JM, Margolis EB, Coker AR, Allen DC, Fields HL.

Alcohol Clin Exp Res. 2014 Jan;38(1):195-203. doi: 10.1111/acer.12246. Epub 2013 Aug 27.


Alcohol self-administration, anxiety, and cortisol levels predict changes in delta opioid receptor function in the ventral tegmental area.

Mitchell JM, Margolis EB, Coker AR, Fields HL.

Behav Neurosci. 2012 Aug;126(4):515-22. doi: 10.1037/a0029027. Epub 2012 Jun 18.


The anticonvulsant levetiracetam potentiates alcohol consumption in non-treatment seeking alcohol abusers.

Mitchell JM, Grossman LE, Coker AR, Messing RO.

J Clin Psychopharmacol. 2012 Apr;32(2):269-72. doi: 10.1097/JCP.0b013e318248ba69.


Reliability in the identification of midbrain dopamine neurons.

Margolis EB, Coker AR, Driscoll JR, Lemaître AI, Fields HL.

PLoS One. 2010 Dec 9;5(12):e15222. doi: 10.1371/journal.pone.0015222.


The high-resolution structure of pig heart succinyl-CoA:3-oxoacid coenzyme A transferase.

Coker SF, Lloyd AJ, Mitchell E, Lewis GR, Coker AR, Shoolingin-Jordan PM.

Acta Crystallogr D Biol Crystallogr. 2010 Jul;66(Pt 7):797-805. doi: 10.1107/S0907444910018366. Epub 2010 Jun 19.


Assembly of a 20-nm protein cage by Escherichia coli 2-hydroxypentadienoic acid hydratase.

Montgomery MG, Coker AR, Taylor IA, Wood SP.

J Mol Biol. 2010 Mar 12;396(5):1379-91. doi: 10.1016/j.jmb.2009.12.056. Epub 2010 Jan 4.


The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology.

Terwilliger TC, Park MS, Waldo GS, Berendzen J, Hung LW, Kim CY, Smith CV, Sacchettini JC, Bellinzoni M, Bossi R, De Rossi E, Mattevi A, Milano A, Riccardi G, Rizzi M, Roberts MM, Coker AR, Fossati G, Mascagni P, Coates AR, Wood SP, Goulding CW, Apostol MI, Anderson DH, Gill HS, Eisenberg DS, Taneja B, Mande S, Pohl E, Lamzin V, Tucker P, Wilmanns M, Colovos C, Meyer-Klaucke W, Munro AW, McLean KJ, Marshall KR, Leys D, Yang JK, Yoon HJ, Lee BI, Lee MG, Kwak JE, Han BW, Lee JY, Baek SH, Suh SW, Komen MM, Arcus VL, Baker EN, Lott JS, Jacobs W Jr, Alber T, Rupp B.

Tuberculosis (Edinb). 2003;83(4):223-49. Review.


Mycobacterium tuberculosis chaperonin 10 heptamers self-associate through their biologically active loops.

Roberts MM, Coker AR, Fossati G, Mascagni P, Coates AR, Wood SP.

J Bacteriol. 2003 Jul;185(14):4172-85.


Molecular chaperone properties of serum amyloid P component.

Coker AR, Purvis A, Baker D, Pepys MB, Wood SP.

FEBS Lett. 2000 May 12;473(2):199-202.


Crystallization, x-ray diffraction and preliminary structure analysis of Mycobacterium tuberculosis chaperonin 10.

Roberts MM, Coker AR, Fossati G, Mascagni P, Coates AR, Wood SP.

Acta Crystallogr D Biol Crystallogr. 1999 Apr;55(Pt 4):910-4.


Renal effects of atrial natriuretic factor (99-126) in conscious sodium-replete sheep.

Yates NA, McDougall JG, Coghlan JP, Coker AR, Gibson AP, Scoggins BA.

Clin Exp Pharmacol Physiol. 1988 Jul;15(7):551-62.


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