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Items: 14


A direct interaction between survivin and myosin II is required for cytokinesis.

Babkoff A, Cohen-Kfir E, Aharon H, Ronen D, Rosenberg M, Wiener R, Ravid S.

J Cell Sci. 2019 Jul 17;132(14). pii: jcs233130. doi: 10.1242/jcs.233130.


Sirt1 Promotes a Thermogenic Gene Program in Bone Marrow Adipocytes: From Mice to (Wo)Men.

Artsi H, Gurt I, El-Haj M, Müller R, Kuhn GA, Ben Shalom G, Cohen-Kfir E, Abramowitz E, Kandel L, Safran O, Dresner-Pollak R.

Front Endocrinol (Lausanne). 2019 Feb 28;10:126. doi: 10.3389/fendo.2019.00126. eCollection 2019.


An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation.

Soudah N, Padala P, Hassouna F, Kumar M, Mashahreh B, Lebedev AA, Isupov MN, Cohen-Kfir E, Wiener R.

J Mol Biol. 2019 Feb 1;431(3):463-478. doi: 10.1016/j.jmb.2018.10.007. Epub 2018 Nov 6.


Trans-binding of UFM1 to UBA5 stimulates UBA5 homodimerization and ATP binding.

Mashahreh B, Hassouna F, Soudah N, Cohen-Kfir E, Strulovich R, Haitin Y, Wiener R.

FASEB J. 2018 May;32(5):2794-2802. doi: 10.1096/fj.201701057R. Epub 2018 Jan 8.


Novel insights into the interaction of UBA5 with UFM1 via a UFM1-interacting sequence.

Padala P, Oweis W, Mashahreh B, Soudah N, Cohen-Kfir E, Todd EA, Berndsen CE, Wiener R.

Sci Rep. 2017 Mar 30;7(1):508. doi: 10.1038/s41598-017-00610-0.


Trans-Binding Mechanism of Ubiquitin-like Protein Activation Revealed by a UBA5-UFM1 Complex.

Oweis W, Padala P, Hassouna F, Cohen-Kfir E, Gibbs DR, Todd EA, Berndsen CE, Wiener R.

Cell Rep. 2016 Sep 20;16(12):3113-3120. doi: 10.1016/j.celrep.2016.08.067.


aPKCζ affects directed cell migration through the regulation of myosin light chain phosphorylation.

Petrov D, Dahan I, Cohen-Kfir E, Ravid S.

Cell Adh Migr. 2017 Jul 4;11(4):347-359. doi: 10.1080/19336918.2016.1225631. Epub 2016 Aug 19.


Reduced Sirtuin1 expression at the femoral neck in women who sustained an osteoporotic hip fracture.

El-Haj M, Gurt I, Cohen-Kfir E, Dixit V, Artsi H, Kandel L, Yakubovsky O, Safran O, Dresner-Pollak R.

Osteoporos Int. 2016 Jul;27(7):2373-2378. doi: 10.1007/s00198-016-3536-4. Epub 2016 Feb 22.


The Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage.

Baiady N, Padala P, Mashahreh B, Cohen-Kfir E, Todd EA, Du Pont KE, Berndsen CE, Wiener R.

J Biol Chem. 2016 Jan 22;291(4):2033-42. doi: 10.1074/jbc.M115.689869. Epub 2015 Nov 24.


The Sirt1 Activators SRT2183 and SRT3025 Inhibit RANKL-Induced Osteoclastogenesis in Bone Marrow-Derived Macrophages and Down-Regulate Sirt3 in Sirt1 Null Cells.

Gurt I, Artsi H, Cohen-Kfir E, Hamdani G, Ben-Shalom G, Feinstein B, El-Haj M, Dresner-Pollak R.

PLoS One. 2015 Jul 30;10(7):e0134391. doi: 10.1371/journal.pone.0134391. eCollection 2015.


The Sirtuin1 activator SRT3025 down-regulates sclerostin and rescues ovariectomy-induced bone loss and biomechanical deterioration in female mice.

Artsi H, Cohen-Kfir E, Gurt I, Shahar R, Bajayo A, Kalish N, Bellido TM, Gabet Y, Dresner-Pollak R.

Endocrinology. 2014 Sep;155(9):3508-15. doi: 10.1210/en.2014-1334. Epub 2014 Jun 20.


The tumor suppressor Lgl1 forms discrete complexes with NMII-A and Par6α-aPKCζ that are affected by Lgl1 phosphorylation.

Dahan I, Petrov D, Cohen-Kfir E, Ravid S.

J Cell Sci. 2014 Jan 15;127(Pt 2):295-304. doi: 10.1242/jcs.127357. Epub 2013 Nov 8.


Sirt1 is a regulator of bone mass and a repressor of Sost encoding for sclerostin, a bone formation inhibitor.

Cohen-Kfir E, Artsi H, Levin A, Abramowitz E, Bajayo A, Gurt I, Zhong L, D'Urso A, Toiber D, Mostoslavsky R, Dresner-Pollak R.

Endocrinology. 2011 Dec;152(12):4514-24. doi: 10.1210/en.2011-1128. Epub 2011 Sep 27.


Zinc inhibition of gamma-aminobutyric acid transporter 4 (GAT4) reveals a link between excitatory and inhibitory neurotransmission.

Cohen-Kfir E, Lee W, Eskandari S, Nelson N.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6154-9. Epub 2005 Apr 13.

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