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Items: 1 to 50 of 356

1.

Efficacy and safety of induction therapy with calcineurin inhibitors followed by vedolizumab maintenance in 71 patients with severe steroid-refractory ulcerative colitis.

Ollech JE, Dwadasi S, Rai V, Peleg N, Normatov I, Israel A, Sossenheimer PH, Christensen B, Pekow J, Dalal SR, Sakuraba A, Cohen RD, Rubin DT.

Aliment Pharmacol Ther. 2019 Dec 25. doi: 10.1111/apt.15616. [Epub ahead of print]

PMID:
31875986
2.

CyClick Chemistry for the Synthesis of Cyclic Peptides.

Adebomi V, Cohen RD, Wills R, Chavers HAH, Martin GE, Raj M.

Angew Chem Int Ed Engl. 2019 Dec 19;58(52):19073-19080. doi: 10.1002/anie.201911900. Epub 2019 Nov 7.

PMID:
31617285
3.

The Safety Profile of Vedolizumab in Ulcerative Colitis and Crohn's Disease: 4 Years of Global Post-marketing Data.

Cohen RD, Bhayat F, Blake A, Travis S.

J Crohns Colitis. 2020 Feb 10;14(2):192-204. doi: 10.1093/ecco-jcc/jjz137.

PMID:
31504340
4.

Follow-Up of Patients With Ulcerative Colitis and Histological Normalization.

Israel A, Christensen B, El Jurdi K, Rai V, Ollech JE, Cohen RD, Sakuraba A, Dalal SR, Rubin DT.

Clin Gastroenterol Hepatol. 2019 Jun 20. pii: S1542-3565(19)30663-9. doi: 10.1016/j.cgh.2019.06.025. [Epub ahead of print]

PMID:
31228567
5.

Ustekinumab Is Effective for the Treatment of Chronic Antibiotic-Refractory Pouchitis.

Ollech JE, Rubin DT, Glick L, Weisshof R, El Jurdi K, Israel A, Krugliak Cleveland N, Hyman N, Sakuraba A, Pekow J, Cohen RD, Dalal SR.

Dig Dis Sci. 2019 Dec;64(12):3596-3601. doi: 10.1007/s10620-019-05697-1. Epub 2019 Jun 11.

6.

Outcome of elective switching to vedolizumab in inflammatory bowel disease patients under tumor necrosis factor antagonist-maintained clinical remission.

Wang Y, Wang J, Pekow J, Dalal S, Cohen RD, Ollech J, Israel A, Shogan BD, Micic D, Cannon L, Umanskiy K, Hurst R, Hyman N, Rubin DT, Sakuraba A.

J Gastroenterol Hepatol. 2019 Dec;34(12):2090-2095. doi: 10.1111/jgh.14751. Epub 2019 Jun 28.

PMID:
31169926
7.

Targeted mutational analysis of inflammatory bowel disease-associated colorectal cancers.

Alpert L, Yassan L, Poon R, Kadri S, Niu N, Patil SA, Mujacic I, Montes D, Galbo F, Wurst MN, Zhen CJ, Cohen RD, Rubin DT, Pekow JR, Weber CR, Xiao SY, Hart J, Segal J, Setia N.

Hum Pathol. 2019 Jul;89:44-50. doi: 10.1016/j.humpath.2019.04.013. Epub 2019 May 2.

PMID:
31054900
8.

Maneuvering Clinical Pathways for Crohn's Disease.

Lu TX, Cohen RD.

Curr Gastroenterol Rep. 2019 Apr 23;21(5):20. doi: 10.1007/s11894-019-0687-4. Review.

PMID:
31016466
9.

Low-Dose Metronidazole is Associated With a Decreased Rate of Endoscopic Recurrence of Crohn's Disease After Ileal Resection: A Retrospective Cohort Study.

Glick LR, Sossenheimer PH, Ollech JE, Cohen RD, Hyman NH, Hurst RD, Rubin DT.

J Crohns Colitis. 2019 Sep 19;13(9):1158-1162. doi: 10.1093/ecco-jcc/jjz047.

PMID:
30809655
10.

Synthesis of Cyanamides via a One-Pot Oxidation-Cyanation of Primary and Secondary Amines.

Kuhl N, Raval S, Cohen RD.

Org Lett. 2019 Mar 1;21(5):1268-1272. doi: 10.1021/acs.orglett.8b04007. Epub 2019 Feb 20.

PMID:
30785295
11.

Differential risk of disease progression between isolated anastomotic ulcers and mild ileal recurrence after ileocolonic resection in patients with Crohn's disease.

Ollech JE, Aharoni-Golan M, Weisshof R, Normatov I, Sapp AR, Kalakonda A, Israel A, Glick LR, Karrison T, Dalal SR, Sakuraba A, Cohen RD, Rubin DT, Pekow J.

Gastrointest Endosc. 2019 Aug;90(2):269-275. doi: 10.1016/j.gie.2019.01.029. Epub 2019 Feb 6.

12.

Real-World Experience with Tofacitinib in IBD at a Tertiary Center.

Weisshof R, Aharoni Golan M, Sossenheimer PH, El Jurdi K, Ollech JE, Pekow J, Cohen RD, Sakuraba A, Dalal S, Rubin DT.

Dig Dis Sci. 2019 Jul;64(7):1945-1951. doi: 10.1007/s10620-019-05492-y. Epub 2019 Feb 7.

13.

Ciclosporin Therapy After Infliximab Failure in Hospitalized Patients With Acute Severe Colitis is Effective and Safe.

Weisshof R, Ollech JE, El Jurdi K, Yvellez OV, Cohen RD, Sakuraba A, Dalal S, Pekow J, Rubin DT.

J Crohns Colitis. 2019 Sep 19;13(9):1105-1110. doi: 10.1093/ecco-jcc/jjz032.

PMID:
30726894
14.

Faecal Calprotectin Is a Very Reliable Tool to Predict and Monitor the Risk of Relapse After Therapeutic De-escalation in Patients With Inflammatory Bowel Diseases.

Buisson A, Mak WY, Andersen MJ, Lei D, Kahn SA, Pekow J, Cohen RD, Zmeter N, Pereira B, Rubin DT.

J Crohns Colitis. 2019 Aug 14;13(8):1012-1024. doi: 10.1093/ecco-jcc/jjz023.

PMID:
30726887
15.

Complete response of metastatic melanoma in a patient with Crohn's disease simultaneously receiving anti-α4β7 and anti-PD1 antibodies.

Frohne CC, Llano EM, Perkovic A, Cohen RD, Luke JJ.

J Immunother Cancer. 2019 Jan 6;7(1):1. doi: 10.1186/s40425-018-0484-x.

16.

Abnormal Pouchogram Predicts Pouch Failure Even in Asymptomatic Patients.

Sossenheimer PH, Glick LR, Dachman AH, Skowron KB, Rubin MA, Umanskiy K, Smith R, Cannon LM, Hurst RD, Cohen RD, Hyman NH, Rubin DT.

Dis Colon Rectum. 2019 Apr;62(4):463-469. doi: 10.1097/DCR.0000000000001285.

PMID:
30540661
17.

Highly Diastereoselective Synthesis of a HCV NS5B Nucleoside Polymerase Inhibitor.

Zhong YL, Cleator E, Liu Z, Yin J, Morris WJ, Alam M, Bishop B, Dumas AM, Edwards J, Goodyear A, Mullens P, Song ZJ, Shevlin M, Thaisrivongs DA, Li H, Sherer EC, Cohen RD, Yin J, Tan L, Yasuda N, Limanto J, Davies A, Campos KR.

J Org Chem. 2019 Apr 19;84(8):4780-4795. doi: 10.1021/acs.joc.8b02500. Epub 2018 Dec 10.

PMID:
30475616
18.

Discovery of a Photoinduced Dark Catalytic Cycle Using in Situ LED-NMR Spectroscopy.

Lehnherr D, Ji Y, Neel AJ, Cohen RD, Brunskill APJ, Yang J, Reibarkh M.

J Am Chem Soc. 2018 Oct 24;140(42):13843-13853. doi: 10.1021/jacs.8b08596. Epub 2018 Oct 10.

PMID:
30244565
19.

A comparison of the risk of postoperative recurrence between African-American and Caucasian patients with Crohn's disease.

Anyane-Yeboa A, Yamada A, Haider H, Wang Y, Komaki Y, Komaki F, Pekow J, Dalal S, Cohen RD, Cannon L, Umanskiy K, Smith R, Hurst R, Hyman N, Rubin DT, Sakuraba A.

Aliment Pharmacol Ther. 2018 Nov;48(9):933-940. doi: 10.1111/apt.14951. Epub 2018 Aug 20.

20.

Amino-Acid-Catalyzed Direct Aldol Bioconjugation.

Howard TS, Cohen RD, Nwajiobi O, Muneeswaran ZP, Sim YE, Lahankar NN, Yeh JT, Raj M.

Org Lett. 2018 Sep 7;20(17):5344-5347. doi: 10.1021/acs.orglett.8b02265. Epub 2018 Aug 20.

PMID:
30125118
21.

Pregnancy Outcomes Reported During the 13-Year TREAT Registry: A Descriptive Report.

Lichtenstein GR, Feagan BG, Mahadevan U, Salzberg BA, Langholff W, Morgan JG, Safdi M, Nissinen R, Taillard F, Sandborn WJ, Cohen RD.

Am J Gastroenterol. 2018 Nov;113(11):1678-1688. doi: 10.1038/s41395-018-0202-9. Epub 2018 Jul 19.

PMID:
30022113
22.

Polarization-independent atomic prism filter for removing amplified spontaneous emission.

Cohen RD, Mullarkey CA, Howell JC, Katz N.

Appl Opt. 2018 Jun 1;57(16):4472-4476. doi: 10.1364/AO.57.004472.

PMID:
29877395
23.

Jizanpeptins, Cyanobacterial Protease Inhibitors from a Symploca sp. Cyanobacterium Collected in the Red Sea.

Gallegos DA, Saurí J, Cohen RD, Wan X, Videau P, Vallota-Eastman AO, Shaala LA, Youssef DTA, Williamson RT, Martin GE, Philmus B, Sikora AE, Ishmael JE, McPhail KL.

J Nat Prod. 2018 Jun 22;81(6):1417-1425. doi: 10.1021/acs.jnatprod.8b00117. Epub 2018 May 29.

PMID:
29808677
24.

Efficacy and Follow-up of Segmental or Subtotal Colectomy in Patients With Colitis-Associated Neoplasia.

Krugliak Cleveland N, Ollech JE, Colman RJ, Rodriquez D, Hirsch A, Cohen RD, Hanauer SB, Hart J, Hurst R, Rubin DT.

Clin Gastroenterol Hepatol. 2019 Jan;17(1):205-206. doi: 10.1016/j.cgh.2018.04.061. Epub 2018 May 8.

25.

Safety and Efficacy of Combination Treatment With Calcineurin Inhibitors and Vedolizumab in Patients With Refractory Inflammatory Bowel Disease.

Christensen B, Gibson PR, Micic D, Colman RJ, Goeppinger SR, Kassim O, Yarur A, Weber CR, Cohen RD, Rubin DT.

Clin Gastroenterol Hepatol. 2019 Feb;17(3):486-493. doi: 10.1016/j.cgh.2018.04.060. Epub 2018 May 8.

26.

A practical strategy for the accurate measurement of residual dipolar couplings in strongly aligned small molecules.

Liu Y, Cohen RD, Martin GE, Williamson RT.

J Magn Reson. 2018 Jun;291:63-72. doi: 10.1016/j.jmr.2018.04.002. Epub 2018 Apr 7.

PMID:
29723716
27.

Cyclic and Lasso Peptides: Sequence Determination, Topology Analysis, and Rotaxane Formation.

Elashal HE, Cohen RD, Elashal HE, Zong C, Link AJ, Raj M.

Angew Chem Int Ed Engl. 2018 May 22;57(21):6150-6154. doi: 10.1002/anie.201801299. Epub 2018 Apr 27.

28.

Beyond optical rotation: what's left is not always right in total synthesis.

Joyce LA, Nawrat CC, Sherer EC, Biba M, Brunskill A, Martin GE, Cohen RD, Davies IW.

Chem Sci. 2017 Oct 30;9(2):415-424. doi: 10.1039/c7sc04249c. eCollection 2018 Jan 14.

29.

Oxazolidinone-Mediated Sequence Determination of One-Bead One-Compound Cyclic Peptide Libraries.

Elashal HE, Cohen RD, Elashal HE, Raj M.

Org Lett. 2018 Apr 20;20(8):2374-2377. doi: 10.1021/acs.orglett.8b00717. Epub 2018 Apr 4.

PMID:
29617143
30.

Observation of untoward 3 Jcc correlations in 1,1-ADEQUATE spectra of pyrimidine analogs: Avoiding potential interpretation pitfalls.

Kim HY, Saurí J, Cohen RD, Martin GE.

Magn Reson Chem. 2018 Aug;56(8):775-781. doi: 10.1002/mrc.4736. Epub 2018 Apr 26.

PMID:
29603782
31.

Vedolizumab as Induction and Maintenance for Inflammatory Bowel Disease: 12-month Effectiveness and Safety.

Christensen B, Colman RJ, Micic D, Gibson PR, Goeppinger SR, Yarur A, Weber CR, Cohen RD, Rubin DT.

Inflamm Bowel Dis. 2018 Mar 19;24(4):849-860. doi: 10.1093/ibd/izx067.

32.

Clinical Response and Complications are not Associated with Drug Levels in Patients with Severe Ulcerative Colitis on IV Cyclosporine Induction Therapy.

Patel P, Yarur A, Dalal S, Sakuraba A, Rubin DT, Hanauer SB, Hanan I, Raffals LH, Cohen RD, Pekow J.

Inflamm Bowel Dis. 2018 May 18;24(6):1291-1297. doi: 10.1093/ibd/izx105.

PMID:
29506124
33.

Enhanced measurement of residual chemical shift anisotropy for small molecule structure elucidation.

Liu Y, Cohen RD, Gustafson KR, Martin GE, Williamson RT.

Chem Commun (Camb). 2018 Apr 24;54(34):4254-4257. doi: 10.1039/c8cc00552d.

34.

Fecal Calprotectin in Assessing Endoscopic and Histological Remission in Patients with Ulcerative Colitis.

Mak WY, Buisson A, Andersen MJ Jr, Lei D, Pekow J, Cohen RD, Kahn SA, Pereira B, Rubin DT.

Dig Dis Sci. 2018 May;63(5):1294-1301. doi: 10.1007/s10620-018-4980-0. Epub 2018 Feb 22.

PMID:
29468374
35.

Infliximab for Crohn's Disease: More Than 13 Years of Real-world Experience.

Lichtenstein GR, Feagan BG, Cohen RD, Salzberg BA, Safdi M, Popp JW Jr, Langholff W, Sandborn WJ.

Inflamm Bowel Dis. 2018 Feb 15;24(3):490-501. doi: 10.1093/ibd/izx072.

36.

The Use of Vedolizumab in Preventing Postoperative Recurrence of Crohn's Disease.

Yamada A, Komaki Y, Patel N, Komaki F, Pekow J, Dalal S, Cohen RD, Cannon L, Umanskiy K, Smith R, Hurst R, Hyman N, Rubin DT, Sakuraba A.

Inflamm Bowel Dis. 2018 Feb 15;24(3):502-509. doi: 10.1093/ibd/izx054.

PMID:
29462385
37.

Assessment of peri-polyp biopsy specimens of flat mucosa in patients with inflammatory bowel disease.

Krugliak Cleveland N, Huo D, Sadiq F, Sofia MA, Marks J, Cohen RD, Hanauer SB, Turner J, Hart J, Rubin DT.

Gastrointest Endosc. 2018 May;87(5):1304-1309. doi: 10.1016/j.gie.2017.12.016. Epub 2018 Jan 4.

PMID:
29307473
38.

Nonmedical Switching of Biosimilars in Patients With Inflammatory Bowel Disease.

Cohen RD.

Gastroenterol Hepatol (N Y). 2017 Nov;13(11):697-699. No abstract available.

39.

Use of Biologic Therapy by Pregnant Women With Inflammatory Bowel Disease Does Not Affect Infant Response to Vaccines.

Beaulieu DB, Ananthakrishnan AN, Martin C, Cohen RD, Kane SV, Mahadevan U.

Clin Gastroenterol Hepatol. 2018 Jan;16(1):99-105. doi: 10.1016/j.cgh.2017.08.041. Epub 2017 Sep 1.

40.

Factors associated with readmission to the hospital within 30 days in patients with inflammatory bowel disease.

Micic D, Gaetano JN, Rubin JN, Cohen RD, Sakuraba A, Rubin DT, Pekow J.

PLoS One. 2017 Aug 24;12(8):e0182900. doi: 10.1371/journal.pone.0182900. eCollection 2017.

41.

Higher Thioguanine Nucleotide Metabolite Levels are Associated With Better Long-term Outcomes in Patients With Inflammatory Bowel Diseases.

Yarur AJ, Gondal B, Hirsch A, Christensen B, Cohen RD, Rubin DT.

J Clin Gastroenterol. 2018 Jul;52(6):537-544. doi: 10.1097/MCG.0000000000000889.

PMID:
28723860
42.

Risk of Postoperative Complications Among Inflammatory Bowel Disease Patients Treated Preoperatively With Vedolizumab.

Yamada A, Komaki Y, Patel N, Komaki F, Aelvoet AS, Tran AL, Pekow J, Dalal S, Cohen RD, Cannon L, Umanskiy K, Smith R, Hurst R, Hyman N, Rubin DT, Sakuraba A.

Am J Gastroenterol. 2017 Sep;112(9):1423-1429. doi: 10.1038/ajg.2017.201. Epub 2017 Jul 18.

PMID:
28719595
43.

Quinary interactions with an unfolded state ensemble.

Cohen RD, Pielak GJ.

Protein Sci. 2017 Sep;26(9):1698-1703. doi: 10.1002/pro.3206. Epub 2017 Jun 12.

44.

Corrigendum: Budesonide Multimatrix Is Efficacious for Mesalamine-refractory, Mild to Moderate Ulcerative Colitis: A Randomised, Placebo-controlled Trial.

Rubin DT, Cohen RD, Sandborn WJ, Lichtenstein GR, Axler J, Riddell RH, Zhu C, Barrett AC, Bortey E, Forbes WP.

J Crohns Colitis. 2017 Dec 4;11(12):1510. doi: 10.1093/ecco-jcc/jjx052. No abstract available.

45.

Budesonide Multimatrix Is Efficacious for Mesalamine-refractory, Mild to Moderate Ulcerative Colitis: A Randomised, Placebo-controlled Trial.

Rubin DT, Cohen RD, Sandborn WJ, Lichtenstein GR, Axler J, Riddell RH, Zhu C, Barrett AC, Bortey E, Forbes WP.

J Crohns Colitis. 2017 Jul 1;11(7):785-791. doi: 10.1093/ecco-jcc/jjx032. Erratum in: J Crohns Colitis. 2017 Dec 4;11(12):1510.

46.

A cell is more than the sum of its (dilute) parts: A brief history of quinary structure.

Cohen RD, Pielak GJ.

Protein Sci. 2017 Mar;26(3):403-413. doi: 10.1002/pro.3092. Epub 2017 Feb 13. Review.

47.

Additional pitfalls of using 1,1-ADEQUATE for structure elucidation.

Cohen RD, Saurí J, Huff CA, Krska SW, Martin GE.

Magn Reson Chem. 2016 Nov;54(11):897-900. doi: 10.1002/mrc.4470. Epub 2016 Jul 10.

PMID:
27396947
48.

Band-Selective 2D HSQMBC: A Universal Technique for Detection and Measurement of 35,37Cl Isotope Effects for 13C Nuclei.

Saurí J, Reibarkh M, Zhang T, Cohen RD, Wang X, Molinski TF, Martin GE, Williamson RT.

Org Lett. 2016 Oct 7;18(19):4786-4789. Epub 2016 Sep 28.

PMID:
27681329
49.

Electrostatic Contributions to Protein Quinary Structure.

Cohen RD, Pielak GJ.

J Am Chem Soc. 2016 Oct 12;138(40):13139-13142. doi: 10.1021/jacs.6b07323. Epub 2016 Oct 4.

PMID:
27676610
50.

Fmoc solid-phase synthesis of C-terminal modified peptides by formation of a backbone cyclic urethane moiety.

Elashal HE, Cohen RD, Raj M.

Chem Commun (Camb). 2016 Aug 11;52(62):9699-702. doi: 10.1039/c6cc04245g. Epub 2016 Jul 13.

PMID:
27407005

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