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Items: 1 to 50 of 169

1.

A Simple In Vitro Gut Model for Studying the Interaction between Escherichia coli and the Intestinal Commensal Microbiota in Cecal Mucus.

Mokszycki ME, Leatham-Jensen M, Steffensen JL, Zhang Y, Krogfelt KA, Caldwell ME, Conway T, Cohen PS.

Appl Environ Microbiol. 2018 Nov 30;84(24). pii: e02166-18. doi: 10.1128/AEM.02166-18. Print 2018 Dec 15.

2.

Uropathogenic Escherichia coli Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection.

Leatham-Jensen MP, Mokszycki ME, Rowley DC, Deering R, Camberg JL, Sokurenko EV, Tchesnokova VL, Frimodt-Møller J, Krogfelt KA, Leth Nielsen K, Frimodt-Møller N, Sun G, Cohen PS.

mSphere. 2016 Jan 20;1(1). pii: e00055-15. doi: 10.1128/mSphere.00055-15. eCollection 2016 Jan-Feb.

3.

Commensal and Pathogenic Escherichia coli Metabolism in the Gut.

Conway T, Cohen PS.

Microbiol Spectr. 2015 Jun;3(3). doi: 10.1128/microbiolspec.MBP-0006-2014.

4.

Escherichia coli EDL933 requires gluconeogenic nutrients to successfully colonize the intestines of streptomycin-treated mice precolonized with E. coli Nissle 1917.

Schinner SA, Mokszycki ME, Adediran J, Leatham-Jensen M, Conway T, Cohen PS.

Infect Immun. 2015 May;83(5):1983-91. doi: 10.1128/IAI.02943-14. Epub 2015 Mar 2.

5.

Escherichia coli pathotypes occupy distinct niches in the mouse intestine.

Meador JP, Caldwell ME, Cohen PS, Conway T.

Infect Immun. 2014 May;82(5):1931-8. doi: 10.1128/IAI.01435-13. Epub 2014 Feb 24.

6.

An Escherichia coli Nissle 1917 missense mutant colonizes the streptomycin-treated mouse intestine better than the wild type but is not a better probiotic.

Adediran J, Leatham-Jensen MP, Mokszycki ME, Frimodt-Møller J, Krogfelt KA, Kazmierczak K, Kenney LJ, Conway T, Cohen PS.

Infect Immun. 2014 Feb;82(2):670-82. doi: 10.1128/IAI.01149-13. Epub 2013 Nov 25.

7.

Nutritional basis for colonization resistance by human commensal Escherichia coli strains HS and Nissle 1917 against E. coli O157:H7 in the mouse intestine.

Maltby R, Leatham-Jensen MP, Gibson T, Cohen PS, Conway T.

PLoS One. 2013;8(1):e53957. doi: 10.1371/journal.pone.0053957. Epub 2013 Jan 17.

8.

Correlations between physical and chemical defences in plants: tradeoffs, syndromes, or just many different ways to skin a herbivorous cat?

Moles AT, Peco B, Wallis IR, Foley WJ, Poore AG, Seabloom EW, Vesk PA, Bisigato AJ, Cella-Pizarro L, Clark CJ, Cohen PS, Cornwell WK, Edwards W, Ejrnaes R, Gonzales-Ojeda T, Graae BJ, Hay G, Lumbwe FC, Magaña-Rodríguez B, Moore BD, Peri PL, Poulsen JR, Stegen JC, Veldtman R, von Zeipel H, Andrew NR, Boulter SL, Borer ET, Cornelissen JH, Farji-Brener AG, DeGabriel JL, Jurado E, Kyhn LA, Low B, Mulder CP, Reardon-Smith K, Rodríguez-Velázquez J, De Fortier A, Zheng Z, Blendinger PG, Enquist BJ, Facelli JM, Knight T, Majer JD, Martínez-Ramos M, McQuillan P, Hui FK.

New Phytol. 2013 Apr;198(1):252-63. doi: 10.1111/nph.12116. Epub 2013 Jan 14.

9.

Carbohydrate utilization by enterohaemorrhagic Escherichia coli O157:H7 in bovine intestinal content.

Bertin Y, Chaucheyras-Durand F, Robbe-Masselot C, Durand A, de la Foye A, Harel J, Cohen PS, Conway T, Forano E, Martin C.

Environ Microbiol. 2013 Feb;15(2):610-22. doi: 10.1111/1462-2920.12019. Epub 2012 Nov 6.

10.

The streptomycin-treated mouse intestine selects Escherichia coli envZ missense mutants that interact with dense and diverse intestinal microbiota.

Leatham-Jensen MP, Frimodt-Møller J, Adediran J, Mokszycki ME, Banner ME, Caughron JE, Krogfelt KA, Conway T, Cohen PS.

Infect Immun. 2012 May;80(5):1716-27. doi: 10.1128/IAI.06193-11. Epub 2012 Mar 5.

11.

Anaerobic respiration of Escherichia coli in the mouse intestine.

Jones SA, Gibson T, Maltby RC, Chowdhury FZ, Stewart V, Cohen PS, Conway T.

Infect Immun. 2011 Oct;79(10):4218-26. doi: 10.1128/IAI.05395-11. Epub 2011 Aug 8.

12.

Putting plant resistance traits on the map: a test of the idea that plants are better defended at lower latitudes.

Moles AT, Wallis IR, Foley WJ, Warton DI, Stegen JC, Bisigato AJ, Cella-Pizarro L, Clark CJ, Cohen PS, Cornwell WK, Edwards W, Ejrnaes R, Gonzales-Ojeda T, Graae BJ, Hay G, Lumbwe FC, Magaña-Rodríguez B, Moore BD, Peri PL, Poulsen JR, Veldtman R, von Zeipel H, Andrew NR, Boulter SL, Borer ET, Campón FF, Coll M, Farji-Brener AG, De Gabriel J, Jurado E, Kyhn LA, Low B, Mulder CP, Reardon-Smith K, Rodríguez-Velázquez J, Seabloom EW, Vesk PA, van Cauter A, Waldram MS, Zheng Z, Blendinger PG, Enquist BJ, Facelli JM, Knight T, Majer JD, Martínez-Ramos M, McQuillan P, Prior LD.

New Phytol. 2011 Aug;191(3):777-88. doi: 10.1111/j.1469-8137.2011.03732.x. Epub 2011 May 3.

13.

Genotype and phenotypes of an intestine-adapted Escherichia coli K-12 mutant selected by animal passage for superior colonization.

Fabich AJ, Leatham MP, Grissom JE, Wiley G, Lai H, Najar F, Roe BA, Cohen PS, Conway T.

Infect Immun. 2011 Jun;79(6):2430-9. doi: 10.1128/IAI.01199-10. Epub 2011 Mar 21.

14.

Precolonized human commensal Escherichia coli strains serve as a barrier to E. coli O157:H7 growth in the streptomycin-treated mouse intestine.

Leatham MP, Banerjee S, Autieri SM, Mercado-Lubo R, Conway T, Cohen PS.

Infect Immun. 2009 Jul;77(7):2876-86. doi: 10.1128/IAI.00059-09. Epub 2009 Apr 13.

15.

The Pic protease of enteroaggregative Escherichia coli promotes intestinal colonization and growth in the presence of mucin.

Harrington SM, Sheikh J, Henderson IR, Ruiz-Perez F, Cohen PS, Nataro JP.

Infect Immun. 2009 Jun;77(6):2465-73. doi: 10.1128/IAI.01494-08. Epub 2009 Apr 6.

16.

Salmonella enterica serovar Typhimurium mutants unable to convert malate to pyruvate and oxaloacetate are avirulent and immunogenic in BALB/c mice.

Mercado-Lubo R, Leatham MP, Conway T, Cohen PS.

Infect Immun. 2009 Apr;77(4):1397-405. doi: 10.1128/IAI.01335-08. Epub 2009 Jan 21.

17.

The biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 18F-AH111585 in healthy volunteers.

McParland BJ, Miller MP, Spinks TJ, Kenny LM, Osman S, Khela MK, Aboagye E, Coombes RC, Hui AM, Cohen PS.

J Nucl Med. 2008 Oct;49(10):1664-7. doi: 10.2967/jnumed.108.052126. Epub 2008 Sep 15.

18.

Phase I trial of the positron-emitting Arg-Gly-Asp (RGD) peptide radioligand 18F-AH111585 in breast cancer patients.

Kenny LM, Coombes RC, Oulie I, Contractor KB, Miller M, Spinks TJ, McParland B, Cohen PS, Hui AM, Palmieri C, Osman S, Glaser M, Turton D, Al-Nahhas A, Aboagye EO.

J Nucl Med. 2008 Jun;49(6):879-86. doi: 10.2967/jnumed.107.049452. Epub 2008 May 15.

19.

Glycogen and maltose utilization by Escherichia coli O157:H7 in the mouse intestine.

Jones SA, Jorgensen M, Chowdhury FZ, Rodgers R, Hartline J, Leatham MP, Struve C, Krogfelt KA, Cohen PS, Conway T.

Infect Immun. 2008 Jun;76(6):2531-40. doi: 10.1128/IAI.00096-08. Epub 2008 Mar 17.

20.

Comparison of carbon nutrition for pathogenic and commensal Escherichia coli strains in the mouse intestine.

Fabich AJ, Jones SA, Chowdhury FZ, Cernosek A, Anderson A, Smalley D, McHargue JW, Hightower GA, Smith JT, Autieri SM, Leatham MP, Lins JJ, Allen RL, Laux DC, Cohen PS, Conway T.

Infect Immun. 2008 Mar;76(3):1143-52. doi: 10.1128/IAI.01386-07. Epub 2008 Jan 7.

21.

A Salmonella enterica serovar typhimurium succinate dehydrogenase/fumarate reductase double mutant is avirulent and immunogenic in BALB/c mice.

Mercado-Lubo R, Gauger EJ, Leatham MP, Conway T, Cohen PS.

Infect Immun. 2008 Mar;76(3):1128-34. Epub 2007 Dec 17.

22.
23.

Respiration of Escherichia coli in the mouse intestine.

Jones SA, Chowdhury FZ, Fabich AJ, Anderson A, Schreiner DM, House AL, Autieri SM, Leatham MP, Lins JJ, Jorgensen M, Cohen PS, Conway T.

Infect Immun. 2007 Oct;75(10):4891-9. Epub 2007 Aug 13.

24.

KIT oncoprotein interactions in gastrointestinal stromal tumors: therapeutic relevance.

Zhu MJ, Ou WB, Fletcher CD, Cohen PS, Demetri GD, Fletcher JA.

Oncogene. 2007 Sep 27;26(44):6386-95. Epub 2007 Apr 23.

PMID:
17452978
25.

Role of motility and the flhDC Operon in Escherichia coli MG1655 colonization of the mouse intestine.

Gauger EJ, Leatham MP, Mercado-Lubo R, Laux DC, Conway T, Cohen PS.

Infect Immun. 2007 Jul;75(7):3315-24. Epub 2007 Apr 16.

26.

Evaluation of a model for Escherichia coli O157:H7 colonization in streptomycin-treated adult cattle.

Snider TA, Fabich AJ, Washburn KE, Sims WP, Blair JL, Cohen PS, Conway T, Clinkenbeard KD.

Am J Vet Res. 2006 Nov;67(11):1914-20.

PMID:
17078755
27.

The multikinase inhibitor midostaurin (PKC412A) lacks activity in metastatic melanoma: a phase IIA clinical and biologic study.

Millward MJ, House C, Bowtell D, Webster L, Olver IN, Gore M, Copeman M, Lynch K, Yap A, Wang Y, Cohen PS, Zalcberg J.

Br J Cancer. 2006 Oct 9;95(7):829-34. Epub 2006 Sep 12.

28.

Role of gluconeogenesis and the tricarboxylic acid cycle in the virulence of Salmonella enterica serovar Typhimurium in BALB/c mice.

Tchawa Yimga M, Leatham MP, Allen JH, Laux DC, Conway T, Cohen PS.

Infect Immun. 2006 Feb;74(2):1130-40.

29.

Mouse intestine selects nonmotile flhDC mutants of Escherichia coli MG1655 with increased colonizing ability and better utilization of carbon sources.

Leatham MP, Stevenson SJ, Gauger EJ, Krogfelt KA, Lins JJ, Haddock TL, Autieri SM, Conway T, Cohen PS.

Infect Immun. 2005 Dec;73(12):8039-49.

30.

Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain.

Heidel F, Solem FK, Breitenbuecher F, Lipka DB, Kasper S, Thiede MH, Brandts C, Serve H, Roesel J, Giles F, Feldman E, Ehninger G, Schiller GJ, Nimer S, Stone RM, Wang Y, Kindler T, Cohen PS, Huber C, Fischer T.

Blood. 2006 Jan 1;107(1):293-300. Epub 2005 Sep 8.

31.

Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation.

Gotlib J, Berubé C, Growney JD, Chen CC, George TI, Williams C, Kajiguchi T, Ruan J, Lilleberg SL, Durocher JA, Lichy JH, Wang Y, Cohen PS, Arber DA, Heinrich MC, Neckers L, Galli SJ, Gilliland DG, Coutré SE.

Blood. 2005 Oct 15;106(8):2865-70. Epub 2005 Jun 21.

32.

The Life of Commensal Escherichia coli in the Mammalian Intestine.

Conway T, Krogfelt KA, Cohen PS.

EcoSal Plus. 2004 Dec;1(1). doi: 10.1128/ecosalplus.8.3.1.2.

PMID:
26443354
33.

PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder.

Chen J, Deangelo DJ, Kutok JL, Williams IR, Lee BH, Wadleigh M, Duclos N, Cohen S, Adelsperger J, Okabe R, Coburn A, Galinsky I, Huntly B, Cohen PS, Meyer T, Fabbro D, Roesel J, Banerji L, Griffin JD, Xiao S, Fletcher JA, Stone RM, Gilliland DG.

Proc Natl Acad Sci U S A. 2004 Oct 5;101(40):14479-84. Epub 2004 Sep 24.

34.

Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML).

Kindler T, Breitenbuecher F, Kasper S, Estey E, Giles F, Feldman E, Ehninger G, Schiller G, Klimek V, Nimer SD, Gratwohl A, Choudhary CR, Mueller-Tidow C, Serve H, Gschaidmeier H, Cohen PS, Huber C, Fischer T.

Blood. 2005 Jan 1;105(1):335-40. Epub 2004 Sep 2.

35.

Carbon nutrition of Escherichia coli in the mouse intestine.

Chang DE, Smalley DJ, Tucker DL, Leatham MP, Norris WE, Stevenson SJ, Anderson AB, Grissom JE, Laux DC, Cohen PS, Conway T.

Proc Natl Acad Sci U S A. 2004 May 11;101(19):7427-32. Epub 2004 May 3.

36.

Glycolytic and gluconeogenic growth of Escherichia coli O157:H7 (EDL933) and E. coli K-12 (MG1655) in the mouse intestine.

Miranda RL, Conway T, Leatham MP, Chang DE, Norris WE, Allen JH, Stevenson SJ, Laux DC, Cohen PS.

Infect Immun. 2004 Mar;72(3):1666-76.

37.

Genes of the GadX-GadW regulon in Escherichia coli.

Tucker DL, Tucker N, Ma Z, Foster JW, Miranda RL, Cohen PS, Conway T.

J Bacteriol. 2003 May;185(10):3190-201.

38.

An Escherichia coli MG1655 lipopolysaccharide deep-rough core mutant grows and survives in mouse cecal mucus but fails to colonize the mouse large intestine.

Møller AK, Leatham MP, Conway T, Nuijten PJ, de Haan LA, Krogfelt KA, Cohen PS.

Infect Immun. 2003 Apr;71(4):2142-52.

39.

Lysophosphatidic acid inhibition of the accumulation of Pseudomonas aeruginosa PAO1 alginate, pyoverdin, elastase and LasA.

Laux DC, Corson JM, Givskov M, Hentzer M, Møller A, Wosencroft KA, Olson JC, Krogfelt KA, Goldberg JB, Cohen PS.

Microbiology. 2002 Jun;148(Pt 6):1709-23.

PMID:
12055291
40.
41.

Specific phospholipids enhance the activity of beta-lactam antibiotics against Pseudomonas aeruginosa.

Krogfelt KA, Utley M, Krivan HC, Laux DC, Cohen PS.

J Antimicrob Chemother. 2000 Sep;46(3):377-84.

PMID:
10980163
42.

A functional cra gene is required for Salmonella enterica serovar typhimurium virulence in BALB/c mice.

Allen JH, Utley M, van Den Bosch H, Nuijten P, Witvliet M, McCormick BA, Krogfelt KA, Licht TR, Brown D, Mauel M, Leatham MP, Laux DC, Cohen PS.

Infect Immun. 2000 Jun;68(6):3772-5.

43.

rpoS gene function is a disadvantage for Escherichia coli BJ4 during competitive colonization of the mouse large intestine.

Krogfelt KA, Hjulgaard M, Sørensen K, Cohen PS, Givskov M.

Infect Immun. 2000 May;68(5):2518-24.

44.

Estimation of growth rates of Escherichia coli BJ4 in streptomycin-treated and previously germfree mice by in situ rRNA hybridization.

Rang CU, Licht TR, Midtvedt T, Conway PL, Chao L, Krogfelt KA, Cohen PS, Molin S.

Clin Diagn Lab Immunol. 1999 May;6(3):434-6.

45.

A Salmonella typhimurium mutant unable to utilize fatty acids and citrate is avirulent and immunogenic in mice.

Utley M, Franklin DP, Krogfelt KA, Laux DC, Cohen PS.

FEMS Microbiol Lett. 1998 Jun 15;163(2):129-34.

47.

Targeted suppression of cytokine production in monocytes but not in T lymphocytes by a tetravalent guanylhydrazone (CNI-1493).

Björk L, Tracey KJ, Ulrich P, Bianchi M, Cohen PS, Akerlund K, Fehniger TE, Andersson U, Andersson J.

J Infect Dis. 1997 Nov;176(5):1303-12.

PMID:
9359732
48.

Recombinant tissue plasminogen activator restores perfusion in meningococcal purpura fulminans.

Aiuto LT, Barone SR, Cohen PS, Boxer RA.

Crit Care Med. 1997 Jun;25(6):1079-82.

PMID:
9201064
49.

Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: a counterregulatory mechanism that restrains the immune response.

Zhang M, Caragine T, Wang H, Cohen PS, Botchkina G, Soda K, Bianchi M, Ulrich P, Cerami A, Sherry B, Tracey KJ.

J Exp Med. 1997 May 19;185(10):1759-68.

50.

The critical role of p38 MAP kinase in T cell HIV-1 replication.

Cohen PS, Schmidtmayerova H, Dennis J, Dubrovsky L, Sherry B, Wang H, Bukrinsky M, Tracey KJ.

Mol Med. 1997 May;3(5):339-46.

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