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Characterization of Injury Induced by Routine Surgical Manipulations of Nasal Septal Cartilage.

Thomas WW, Brody RM, Alotaibi AD, Rabut EC, Cohen NA, Lyman R, Kovacevic M, Friedman O, Dodge GR.

JAMA Facial Plast Surg. 2019 May 30. doi: 10.1001/jamafacial.2019.0169. [Epub ahead of print]


Psoriatic patients have a distinct structural and functional fecal microbiota compared with controls.

Shapiro J, Cohen NA, Shalev V, Uzan A, Koren O, Maharshak N.

J Dermatol. 2019 Jul;46(7):595-603. doi: 10.1111/1346-8138.14933. Epub 2019 May 29.


Inverted papilloma with multifocal attachment is associated with increased recurrence.

Tong CCL, Patel NN, Maina IW, Triantafillou V, Yan CH, Kuan EC, Kohanski MA, Papagiannopoulos P, Workman AD, Cohen NA, Kennedy DW, Adappa ND, Palmer JN.

Int Forum Allergy Rhinol. 2019 Aug;9(8):865-869. doi: 10.1002/alr.22342. Epub 2019 May 24.


Fecal Proteases from Pouchitis Patients Activate Protease Activating Receptor-2 to Disrupt the Epithelial Barrier.

Hoffman S, Cohen NA, Carroll IM, Tulchinsky H, Borovok I, Dotan I, Maharshak N.

J Crohns Colitis. 2019 May 6. pii: jjz086. doi: 10.1093/ecco-jcc/jjz086. [Epub ahead of print]


Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells.

Santamaria-Barria JA, Zeng S, Greer JB, Beckman MJ, Seifert AM, Cohen NA, Zhang JQ, Crawley MH, Green BL, Loo JK, Maltbaek JH, DeMatteo RP.

PLoS One. 2019 May 1;14(5):e0216275. doi: 10.1371/journal.pone.0216275. eCollection 2019.


Development of solitary chemosensory cells in the distal lung after severe influenza injury.

Rane CK, Jackson SR, Pastore CF, Zhao G, Weiner AI, Patel NN, Herbert DR, Cohen NA, Vaughan AE.

Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1;316(6):L1141-L1149. doi: 10.1152/ajplung.00032.2019. Epub 2019 Mar 25.


Fungal extracts stimulate solitary chemosensory cell expansion in noninvasive fungal rhinosinusitis.

Patel NN, Triantafillou V, Maina IW, Workman AD, Tong CCL, Kuan EC, Papagiannopoulos P, Bosso JV, Adappa ND, Palmer JN, Kohanski MA, Herbert DR, Cohen NA.

Int Forum Allergy Rhinol. 2019 Jul;9(7):730-737. doi: 10.1002/alr.22334. Epub 2019 Mar 20.


Implementation of a medical coding curriculum for surgery residents.

Kelley KA, Hoops HE, Palmer L, Cohen NA, Brasel KJ.

Am J Surg. 2019 May;217(5):834-838. doi: 10.1016/j.amjsurg.2019.02.027. Epub 2019 Mar 4.


Understanding the Role of Biofilms and Superantigens in Chronic Rhinosinusitis.

Maina IW, Patel NN, Cohen NA.

Curr Otorhinolaryngol Rep. 2018 Sep;6(3):253-262. doi: 10.1007/s40136-018-0212-6. Epub 2018 Jul 26.


Broncho-Vaxom® (OM-85 BV) soluble components stimulate sinonasal innate immunity.

Triantafillou V, Workman AD, Patel NN, Maina IW, Tong CCL, Kuan EC, Kennedy DW, Palmer JN, Adappa ND, Waizel-Haiat S, Cohen NA.

Int Forum Allergy Rhinol. 2019 Apr;9(4):370-377. doi: 10.1002/alr.22276. Epub 2019 Jan 7.


Five years of fecal microbiota transplantation - an update of the Israeli experience.

Greenberg SA, Youngster I, Cohen NA, Livovsky DM, Strahilevitz J, Israeli E, Melzer E, Paz K, Fliss-Isakov N, Maharshak N.

World J Gastroenterol. 2018 Dec 21;24(47):5403-5414. doi: 10.3748/wjg.v24.i47.5403.


The role of bitter and sweet taste receptors in upper airway innate immunity: Recent advances and future directions.

Maina IW, Workman AD, Cohen NA.

World J Otorhinolaryngol Head Neck Surg. 2018 Aug 24;4(3):200-208. doi: 10.1016/j.wjorl.2018.07.003. eCollection 2018 Sep. Review.


The human olfactory cleft mucus proteome and its age-related changes.

Yoshikawa K, Wang H, Jaen C, Haneoka M, Saito N, Nakamura J, Adappa ND, Cohen NA, Dalton P.

Sci Rep. 2018 Nov 21;8(1):17170. doi: 10.1038/s41598-018-35102-2.


Minimally Invasive Staging Surgery for Cancer.

Cohen NA, Kingham TP.

Surg Oncol Clin N Am. 2019 Jan;28(1):61-77. doi: 10.1016/j.soc.2018.07.006. Epub 2018 Oct 23. Review.


Role of Taste Receptors as Sentinels of Innate Immunity in the Upper Airway.

Patel NN, Workman AD, Cohen NA.

J Pathog. 2018 Oct 1;2018:9541987. doi: 10.1155/2018/9541987. eCollection 2018. Review.


Species-level bacterial community profiling of the healthy sinonasal microbiome using Pacific Biosciences sequencing of full-length 16S rRNA genes.

Earl JP, Adappa ND, Krol J, Bhat AS, Balashov S, Ehrlich RL, Palmer JN, Workman AD, Blasetti M, Sen B, Hammond J, Cohen NA, Ehrlich GD, Mell JC.

Microbiome. 2018 Oct 23;6(1):190. doi: 10.1186/s40168-018-0569-2.


Tissue-Dependent Expression of Bitter Receptor TAS2R38 mRNA.

Douglas JE, Lin C, Mansfield CJ, Arayata CJ, Cowart BJ, Spielman AI, Adappa ND, Palmer JN, Cohen NA, Reed DR.

Chem Senses. 2019 Jan 1;44(1):33-40. doi: 10.1093/chemse/bjy066.


Biomarkers in Chronic Rhinosinusitis with Nasal Polyps.

Workman AD, Kohanski MA, Cohen NA.

Immunol Allergy Clin North Am. 2018 Nov;38(4):679-692. doi: 10.1016/j.iac.2018.06.006. Epub 2018 Sep 21. Review.


Macrophages promote epithelial proliferation following infectious and non-infectious lung injury through a Trefoil factor 2-dependent mechanism.

Hung LY, Sen D, Oniskey TK, Katzen J, Cohen NA, Vaughan AE, Nieves W, Urisman A, Beers MF, Krummel MF, Herbert DR.

Mucosal Immunol. 2019 Jan;12(1):64-76. doi: 10.1038/s41385-018-0096-2. Epub 2018 Oct 18.


Sentinels at the wall: epithelial-derived cytokines serve as triggers of upper airway type 2 inflammation.

Patel NN, Kohanski MA, Maina IW, Workman AD, Herbert DR, Cohen NA.

Int Forum Allergy Rhinol. 2019 Jan;9(1):93-99. doi: 10.1002/alr.22206. Epub 2018 Sep 10. Review.


Taste Exam: A Brief and Validated Test.

Douglas JE, Mansfield CJ, Arayata CJ, Cowart BJ, Colquitt LR, Maina IW, Blasetti MT, Cohen NA, Reed DR.

J Vis Exp. 2018 Aug 17;(138). doi: 10.3791/56705.


Clostridium difficile fecal toxin level is associated with disease severity and prognosis.

Cohen NA, Miller T, Na'aminh W, Hod K, Adler A, Cohen D, Guzner-Gur H, Santo E, Halpern Z, Carmeli Y, Maharshak N.

United European Gastroenterol J. 2018 Jun;6(5):773-780. doi: 10.1177/2050640617750809. Epub 2017 Dec 21.


Lack of Diagnosis of Pneumoperitoneum in Perforated Duodenal Ulcer After RYGB: a Short Case Series and Review of the Literature.

Zagzag J, Cohen NA, Fielding G, Saunders J, Sinha P, Parikh M, Shah P, Hindman N, Ren-Fielding C.

Obes Surg. 2018 Sep;28(9):2976-2978. doi: 10.1007/s11695-018-3321-x.


Checkpoint blockade in esophagogastric cancer.

Cohen NA, Strong VE, Janjigian YY.

J Surg Oncol. 2018 Jul;118(1):77-85. doi: 10.1002/jso.25116. Epub 2018 Jun 7. Review.


Solitary chemosensory cells are a primary epithelial source of IL-25 in patients with chronic rhinosinusitis with nasal polyps.

Kohanski MA, Workman AD, Patel NN, Hung LY, Shtraks JP, Chen B, Blasetti M, Doghramji L, Kennedy DW, Adappa ND, Palmer JN, Herbert DR, Cohen NA.

J Allergy Clin Immunol. 2018 Aug;142(2):460-469.e7. doi: 10.1016/j.jaci.2018.03.019. Epub 2018 May 17.


Solitary chemosensory cells producing interleukin-25 and group-2 innate lymphoid cells are enriched in chronic rhinosinusitis with nasal polyps.

Patel NN, Kohanski MA, Maina IW, Triantafillou V, Workman AD, Tong CCL, Kuan EC, Bosso JV, Adappa ND, Palmer JN, Herbert DR, Cohen NA.

Int Forum Allergy Rhinol. 2018 May 9. doi: 10.1002/alr.22142. [Epub ahead of print]


The Role of Quinine-Responsive Taste Receptor Family 2 in Airway Immune Defense and Chronic Rhinosinusitis.

Workman AD, Maina IW, Brooks SG, Kohanski MA, Cowart BJ, Mansfield C, Kennedy DW, Palmer JN, Adappa ND, Reed DR, Lee RJ, Cohen NA.

Front Immunol. 2018 Mar 28;9:624. doi: 10.3389/fimmu.2018.00624. eCollection 2018.


Taste Receptor Polymorphisms and Immune Response: A Review of Receptor Genotypic-Phenotypic Variations and Their Relevance to Chronic Rhinosinusitis.

Triantafillou V, Workman AD, Kohanski MA, Cohen NA.

Front Cell Infect Microbiol. 2018 Mar 7;8:64. doi: 10.3389/fcimb.2018.00064. eCollection 2018. Review.


Preoperative Lund-Mackay computed tomography score is associated with preoperative symptom severity and predicts quality-of-life outcome trajectories after sinus surgery.

Brooks SG, Trope M, Blasetti M, Doghramji L, Parasher A, Glicksman JT, Kennedy DW, Thaler ER, Cohen NA, Palmer JN, Adappa ND.

Int Forum Allergy Rhinol. 2018 Jun;8(6):668-675. doi: 10.1002/alr.22109. Epub 2018 Mar 8.


Trefoil Factor 2 Promotes Type 2 Immunity and Lung Repair through Intrinsic Roles in Hematopoietic and Nonhematopoietic Cells.

Hung LY, Oniskey TK, Sen D, Krummel MF, Vaughan AE, Cohen NA, Herbert DR.

Am J Pathol. 2018 May;188(5):1161-1170. doi: 10.1016/j.ajpath.2018.01.020. Epub 2018 Feb 16.


Bitter and sweet taste tests are reflective of disease status in chronic rhinosinusitis.

Workman AD, Brooks SG, Kohanski MA, Blasetti MT, Cowart BJ, Mansfield C, Kennedy DW, Palmer JN, Adappa ND, Reed DR, Cohen NA.

J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):1078-1080. doi: 10.1016/j.jaip.2017.09.014. Epub 2017 Oct 18. No abstract available.


Bacterial d-amino acids suppress sinonasal innate immunity through sweet taste receptors in solitary chemosensory cells.

Lee RJ, Hariri BM, McMahon DB, Chen B, Doghramji L, Adappa ND, Palmer JN, Kennedy DW, Jiang P, Margolskee RF, Cohen NA.

Sci Signal. 2017 Sep 5;10(495). pii: eaam7703. doi: 10.1126/scisignal.aam7703.


Medical management of chronic rhinosinusitis - a review of traditional and novel medical therapies.

Schwartz JS, Tajudeen BA, Cohen NA.

Expert Opin Investig Drugs. 2017 Oct;26(10):1123-1130. doi: 10.1080/13543784.2017.1371699. Epub 2017 Sep 5. Review.


CALHM1-Mediated ATP Release and Ciliary Beat Frequency Modulation in Nasal Epithelial Cells.

Workman AD, Carey RM, Chen B, Saunders CJ, Marambaud P, Mitchell CH, Tordoff MG, Lee RJ, Cohen NA.

Sci Rep. 2017 Jul 27;7(1):6687. doi: 10.1038/s41598-017-07221-9.


Sinonasal T2R-mediated nitric oxide production in response to Bacillus cereus.

Carey RM, Workman AD, Yan CH, Chen B, Adappa ND, Palmer JN, Kennedy DW, Lee RJ, Cohen NA.

Am J Rhinol Allergy. 2017 Jul 1;31(4):211-215. doi: 10.2500/ajra.2017.31.4453.


Wnt/β-catenin Signaling Contributes to Tumor Malignancy and Is Targetable in Gastrointestinal Stromal Tumor.

Zeng S, Seifert AM, Zhang JQ, Cavnar MJ, Kim TS, Balachandran VP, Santamaria-Barria JA, Cohen NA, Beckman MJ, Medina BD, Rossi F, Crawley MH, Loo JK, Maltbaek JH, Besmer P, Antonescu CR, DeMatteo RP.

Mol Cancer Ther. 2017 Sep;16(9):1954-1966. doi: 10.1158/1535-7163.MCT-17-0139. Epub 2017 Jun 13.


Effects of ophthalmologic solutions on sinonasal ciliated epithelium.

Workman AD, Carey RM, Kohanski MA, Adappa ND, Palmer JN, Cohen NA.

Int Forum Allergy Rhinol. 2017 Aug;7(8):801-808. doi: 10.1002/alr.21953. Epub 2017 May 23.


Relative susceptibility of airway organisms to antimicrobial effects of nitric oxide.

Workman AD, Carey RM, Kohanski MA, Kennedy DW, Palmer JN, Adappa ND, Cohen NA.

Int Forum Allergy Rhinol. 2017 Aug;7(8):770-776. doi: 10.1002/alr.21966. Epub 2017 May 25.


Denatonium-induced sinonasal bacterial killing may play a role in chronic rhinosinusitis outcomes.

Carey RM, Workman AD, Hatten KM, Siebert AP, Brooks SG, Chen B, Adappa ND, Palmer JN, Kennedy DW, Lee RJ, Cohen NA.

Int Forum Allergy Rhinol. 2017 Jul;7(7):699-704. doi: 10.1002/alr.21949. Epub 2017 May 23.


Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation.

Sorenson EC, Khanin R, Bamboat ZM, Cavnar MJ, Kim TS, Sadot E, Zeng S, Greer JB, Seifert AM, Cohen NA, Crawley MH, Green BL, Klimstra DS, DeMatteo RP.

PLoS One. 2017 May 9;12(5):e0176562. doi: 10.1371/journal.pone.0176562. eCollection 2017.


A Retrospective Comparison of Fecal Microbial Transplantation Methods for Recurrent Clostridium Difficile Infection.

Cohen NA, Livovsky DM, Yaakobovitch S, Ben Yehoyada M, Ben Ami R, Adler A, Guzner-Gur H, Goldin E, Santo ME, Halpern Z, Paz K, Maharshak N.

Isr Med Assoc J. 2016 Oct;18(10):594-599.


Nitric oxide production is stimulated by bitter taste receptors ubiquitously expressed in the sinonasal cavity.

Yan CH, Hahn S, McMahon D, Bonislawski D, Kennedy DW, Adappa ND, Palmer JN, Jiang P, Lee RJ, Cohen NA.

Am J Rhinol Allergy. 2017 Mar 1;31(2):85-92. doi: 10.2500/ajra.2017.31.4424.


Process Improvement Initiative for the Perioperative Management of Patients With a Cardiovascular Implantable Electronic Device.

Ellis MKM, Treggiari MM, Robertson JM, Rozner MA, Graven PF, Aziz MF, Merkel MJ, Kahl EA, Cohen NA, Stecker EC, Schulman PM.

Anesth Analg. 2017 Jul;125(1):58-65. doi: 10.1213/ANE.0000000000001953.


Novel Indications for Fecal Microbial Transplantation: Update and Review of the Literature.

Cohen NA, Maharshak N.

Dig Dis Sci. 2017 May;62(5):1131-1145. doi: 10.1007/s10620-017-4535-9. Epub 2017 Mar 17. Review.


Taste Receptors Mediate Sinonasal Immunity and Respiratory Disease.

Douglas JE, Cohen NA.

Int J Mol Sci. 2017 Feb 17;18(2). pii: E437. doi: 10.3390/ijms18020437. Review.


TNFα Affects Ciliary Beat Response to Increased Viscosity in Human Pediatric Airway Epithelium.

González C, Droguett K, Rios M, Cohen NA, Villalón M.

Biomed Res Int. 2016;2016:3628501. doi: 10.1155/2016/3628501. Epub 2016 Nov 29.


Myrtol standardized affects mucociliary clearance.

Li YY, Liu J, Li CW, Subramaniam S, Chao SS, Yu FG, Cohen NA, Li S, Wang Y.

Int Forum Allergy Rhinol. 2017 Mar;7(3):304-311. doi: 10.1002/alr.21878. Epub 2016 Nov 26.


Taste Receptors: Regulators of Sinonasal Innate Immunity.

Carey RM, Adappa ND, Palmer JN, Lee RJ, Cohen NA.

Laryngoscope Investig Otolaryngol. 2016 Aug;1(4):88-95. Epub 2016 Jun 28.


Interleukin-17A (IL-17A) and IL-17F Are Critical for Antimicrobial Peptide Production and Clearance of Staphylococcus aureus Nasal Colonization.

Archer NK, Adappa ND, Palmer JN, Cohen NA, Harro JM, Lee SK, Miller LS, Shirtliff ME.

Infect Immun. 2016 Nov 18;84(12):3575-3583. Print 2016 Dec.


New insights into upper airway innate immunity.

Hariri BM, Cohen NA.

Am J Rhinol Allergy. 2016 Sep;30(5):319-23. doi: 10.2500/ajra.2016.30.4360. Review.

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