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Items: 1 to 50 of 2292

1.

The Ethics of Heritable Genome Editing: New Considerations in a Controversial Area.

Adashi EY, Cohen IG.

JAMA. 2018 Dec 3. doi: 10.1001/jama.2018.18270. [Epub ahead of print] No abstract available.

PMID:
30508029
2.

Autism Spectrum Disorder Decision Tree Subgroups Predict Adaptive Behavior and Autism Severity Trajectories in Children with ASD.

Cohen IL, Flory MJ.

J Autism Dev Disord. 2018 Dec 3. doi: 10.1007/s10803-018-3830-4. [Epub ahead of print]

PMID:
30511124
3.

Kinetic Equilibrium of Dipolarization Fronts.

Ganguli G, Crabtree C, Fletcher AC, Tejero E, Malaspina D, Cohen I.

Sci Rep. 2018 Nov 21;8(1):17186. doi: 10.1038/s41598-018-35349-9.

4.

Losing Embryos, Finding Justice: Life, Liberty, and the Pursuit of Personhood.

Cohen IG, Fox D, Adashi EY.

Ann Intern Med. 2018 Dec 4;169(11):800-801. doi: 10.7326/M18-2483. Epub 2018 Nov 20. No abstract available.

PMID:
30458508
5.

Electron-scale dynamics of the diffusion region during symmetric magnetic reconnection in space.

Torbert RB, Burch JL, Phan TD, Hesse M, Argall MR, Shuster J, Ergun RE, Alm L, Nakamura R, Genestreti KJ, Gershman DJ, Paterson WR, Turner DL, Cohen I, Giles BL, Pollock CJ, Wang S, Chen LJ, Stawarz JE, Eastwood JP, Hwang KJ, Farrugia C, Dors I, Vaith H, Mouikis C, Ardakani A, Mauk BH, Fuselier SA, Russell CT, Strangeway RJ, Moore TE, Drake JF, Shay MA, Khotyaintsev YV, Lindqvist PA, Baumjohann W, Wilder FD, Ahmadi N, Dorelli JC, Avanov LA, Oka M, Baker DN, Fennell JF, Blake JB, Jaynes AN, Le Contel O, Petrinec SM, Lavraud B, Saito Y.

Science. 2018 Nov 15. pii: eaat2998. doi: 10.1126/science.aat2998. [Epub ahead of print]

PMID:
30442767
6.

Machine learning in medicine: Addressing ethical challenges.

Vayena E, Blasimme A, Cohen IG.

PLoS Med. 2018 Nov 6;15(11):e1002689. doi: 10.1371/journal.pmed.1002689. eCollection 2018 Nov.

7.

Successful implementation of an intracranial hemorrhage (ICH) bundle in reducing severe ICH: a quality improvement project.

Chiriboga N, Cortez J, Pena-Ariet A, Makker K, Smotherman C, Gautam S, Trikardos AB, Knight H, Yeoman M, Burnett E, Beier A, Cohen I, Hudak ML.

J Perinatol. 2018 Oct 22. doi: 10.1038/s41372-018-0257-x. [Epub ahead of print]

PMID:
30348961
8.

Response to Open Peer Commentaries on "The Ethics of Smart Pills and Self-Acting Devices: Autonomy, Truth-Telling, and Trust at the Dawn of Digital Medicine".

Klugman CM, Dunn LB, Schwartz J, Cohen IG.

Am J Bioeth. 2018 Oct;18(10):W4-W7. doi: 10.1080/15265161.2018.1514427. No abstract available.

PMID:
30339081
9.

Oversight of Patient-Centered Outcomes Research: Recommendations From a Delphi Panel.

Gelinas L, Weissman JS, Lynch HF, Gupta A, Rozenblum R, Largent EA, Cohen IG; Delphi Working Group Participants.

Ann Intern Med. 2018 Oct 16;169(8):559-563. doi: 10.7326/M18-1334. Epub 2018 Sep 25.

PMID:
30264127
10.

Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries.

Naftaly S, Cohen I, Shahar A, Hockla A, Radisky ES, Papo N.

Nat Commun. 2018 Sep 26;9(1):3935. doi: 10.1038/s41467-018-06403-x.

11.

LDH-A regulates the tumor microenvironment via HIF-signaling and modulates the immune response.

Serganova I, Cohen IJ, Vemuri K, Shindo M, Maeda M, Mane M, Moroz E, Khanin R, Satagopan J, Koutcher JA, Blasberg R.

PLoS One. 2018 Sep 24;13(9):e0203965. doi: 10.1371/journal.pone.0203965. eCollection 2018.

12.

The importance of adequate methotrexate and adequate folinic acid rescue doses in the treatment of primary brain lymphoma.

Cohen IJ.

J Neurooncol. 2018 Dec;140(3):757. doi: 10.1007/s11060-018-2999-x. Epub 2018 Sep 21. No abstract available.

PMID:
30242556
13.

The Ethics of Smart Pills and Self-Acting Devices: Autonomy, Truth-Telling, and Trust at the Dawn of Digital Medicine.

Klugman CM, Dunn LB, Schwartz J, Cohen IG.

Am J Bioeth. 2018 Sep;18(9):38-47. doi: 10.1080/15265161.2018.1498933.

PMID:
30235091
14.

Autogenous and efficient acceleration of energetic ions upstream of Earth's bow shock.

Turner DL, Wilson LB 3rd, Liu TZ, Cohen IJ, Schwartz SJ, Osmane A, Fennell JF, Clemmons JH, Blake JB, Westlake J, Mauk BH, Jaynes AN, Leonard T, Baker DN, Strangeway RJ, Russell CT, Gershman DJ, Avanov L, Giles BL, Torbert RB, Broll J, Gomez RG, Fuselier SA, Burch JL.

Nature. 2018 Sep;561(7722):206-210. doi: 10.1038/s41586-018-0472-9. Epub 2018 Sep 12.

PMID:
30209369
15.

Density-functional fluctuation theory of crowds.

Méndez-Valderrama JF, Kinkhabwala YA, Silver J, Cohen I, Arias TA.

Nat Commun. 2018 Aug 30;9(1):3538. doi: 10.1038/s41467-018-05750-z.

16.

Data-Driven Tree Transforms and Metrics.

Mishne G, Talmon R, Cohen I, Coifman RR, Kluger Y.

IEEE Trans Signal Inf Process Netw. 2018 Sep;4(3):451-466. doi: 10.1109/TSIPN.2017.2743561. Epub 2017 Aug 23.

17.

Publisher Correction: FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells.

Nguyen MB, Cohen I, Kumar V, Xu Z, Bar C, Dauber-Decker KL, Tsai PC, Marangoni P, Klein OD, Hsu YC, Chen T, Mikkola ML, Ezhkova E.

Nat Commun. 2018 Jul 17;9(1):2854. doi: 10.1038/s41467-018-05361-8.

18.

Personhood and the Three Branches of Government.

Cohen IG, Adashi EY.

N Engl J Med. 2018 Jun 28;378(26):2453-2455. doi: 10.1056/NEJMp1801940. No abstract available.

19.

Multiscale Currents Observed by MMS in the Flow Braking Region.

Nakamura R, Varsani A, Genestreti KJ, Le Contel O, Nakamura T, Baumjohann W, Nagai T, Artemyev A, Birn J, Sergeev VA, Apatenkov S, Ergun RE, Fuselier SA, Gershman DJ, Giles BJ, Khotyaintsev YV, Lindqvist PA, Magnes W, Mauk B, Petrukovich A, Russell CT, Stawarz J, Strangeway RJ, Anderson B, Burch JL, Bromund KR, Cohen I, Fischer D, Jaynes A, Kepko L, Le G, Plaschke F, Reeves G, Singer HJ, Slavin JA, Torbert RB, Turner DL.

J Geophys Res Space Phys. 2018 Feb;123(2):1260-1278. doi: 10.1002/2017JA024686. Epub 2018 Feb 20.

20.

A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering.

Sananes A, Cohen I, Shahar A, Hockla A, De Vita E, Miller AK, Radisky ES, Papo N.

J Biol Chem. 2018 Aug 17;293(33):12663-12680. doi: 10.1074/jbc.RA117.000871. Epub 2018 Jun 22.

PMID:
29934309
21.

Anterior Thalamic Excitation and Feedforward Inhibition of Presubicular Neurons Projecting to Medial Entorhinal Cortex.

Nassar M, Simonnet J, Huang LW, Mathon B, Cohen I, Bendels MHK, Beraneck M, Miles R, Fricker D.

J Neurosci. 2018 Jul 11;38(28):6411-6425. doi: 10.1523/JNEUROSCI.0014-18.2018. Epub 2018 Jun 19.

PMID:
29921712
22.

IRB Oversight of Patient-Centered Outcomes Research: A National Survey of IRB Chairpersons.

Weissman JS, Campbell EG, Cohen IG, Lynch HF, Largent EA, Gupta A, Rozenblum R, Abraham M, Spikes K, Fagan M, Carnie M.

J Empir Res Hum Res Ethics. 2018 Oct;13(4):421-431. doi: 10.1177/1556264618779785. Epub 2018 Jun 14.

PMID:
29902953
23.

FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells.

Nguyen MB, Cohen I, Kumar V, Xu Z, Bar C, Dauber-Decker KL, Tsai PC, Marangoni P, Klein OD, Hsu YC, Chen T, Mikkola ML, Ezhkova E.

Nat Commun. 2018 Jun 13;9(1):2333. doi: 10.1038/s41467-018-04399-y. Erratum in: Nat Commun. 2018 Jul 17;9(1):2854.

24.

Building Capacity for a Global Genome Editing Observatory: Institutional Design.

Saha K, Hurlbut JB, Jasanoff S, Ahmed A, Appiah A, Bartholet E, Baylis F, Bennett G, Church G, Cohen IG, Daley G, Finneran K, Hurlbut W, Jaenisch R, Lwoff L, Kimes JP, Mills P, Moses J, Park BS, Parens E, Salzman R, Saxena A, Simmet H, Simoncelli T, Snead OC, Rajan KS, Truog RD, Williams P, Woopen C.

Trends Biotechnol. 2018 Aug;36(8):741-743. doi: 10.1016/j.tibtech.2018.04.008. Epub 2018 Jun 8.

PMID:
29891181
25.

The SLE-key test serological signature: new insights into the course of lupus.

Putterman C, Pisetsky DS, Petri M, Caricchio R, Wu AHB, Sanz I, Oates JC, Wallace S, Sorek R, Gerwien R, Safer P, Jakobi-Brook K, Cohen IR.

Rheumatology (Oxford). 2018 Sep 1;57(9):1632-1640. doi: 10.1093/rheumatology/key149.

PMID:
29873771
26.

Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges.

Hurlbut JB, Jasanoff S, Saha K, Ahmed A, Appiah A, Bartholet E, Baylis F, Bennett G, Church G, Cohen IG, Daley G, Finneran K, Hurlbut W, Jaenisch R, Lwoff L, Kimes JP, Mills P, Moses J, Park BS, Parens E, Salzman R, Saxena A, Simmet H, Simoncelli T, Snead OC, Rajan KS, Truog RD, Williams P, Woopen C.

Trends Biotechnol. 2018 Jul;36(7):639-641. doi: 10.1016/j.tibtech.2018.04.009. Epub 2018 Jun 2.

PMID:
29871776
27.

The effects of elevated CO2 and nitrogen nutrition on root dynamics.

Cohen I, Rapaport T, Berger RT, Rachmilevitch S.

Plant Sci. 2018 Jul;272:294-300. doi: 10.1016/j.plantsci.2018.03.034. Epub 2018 Apr 11.

PMID:
29807602
28.

HIPAA and Protecting Health Information in the 21st Century.

Cohen IG, Mello MM.

JAMA. 2018 Jul 17;320(3):231-232. doi: 10.1001/jama.2018.5630. No abstract available.

PMID:
29800120
29.

Synergistic effects of abiotic stresses in plants: a case study of nitrogen limitation and saturating light intensity in Arabidopsis thaliana.

Cohen I, Rapaport T, Chalifa-Caspi V, Rachmilevitch S.

Physiol Plant. 2018 May 22. doi: 10.1111/ppl.12765. [Epub ahead of print]

PMID:
29786859
30.

Bromide Ions Specific Removal and Recovery by Electrochemical Desalination.

Cohen I, Shapira B, Avraham E, Soffer A, Aurbach D.

Environ Sci Technol. 2018 Jun 5;52(11):6275-6281. doi: 10.1021/acs.est.8b00282. Epub 2018 May 22.

PMID:
29749732
31.

Heat shock protein 60 enhances CD4+CD25+ regulatory T cell function via innate TLR2 signaling.

Zanin-Zhorov A, Cahalon L, Tal G, Margalit R, Lider O, Cohen IR.

J Clin Invest. 2018 Jun 1;128(6):2651. doi: 10.1172/JCI121856. Epub 2018 May 7. No abstract available.

32.

Microscale frictional strains determine chondrocyte fate in loaded cartilage.

Bonnevie ED, Delco ML, Bartell LR, Jasty N, Cohen I, Fortier LA, Bonassar LJ.

J Biomech. 2018 Jun 6;74:72-78. doi: 10.1016/j.jbiomech.2018.04.020. Epub 2018 Apr 25.

PMID:
29729853
33.

PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification.

Cohen I, Zhao D, Bar C, Valdes VJ, Dauber-Decker KL, Nguyen MB, Nakayama M, Rendl M, Bickmore WA, Koseki H, Zheng D, Ezhkova E.

Cell Stem Cell. 2018 May 3;22(5):726-739.e7. doi: 10.1016/j.stem.2018.04.005.

PMID:
29727681
34.

Truth in Advertising: Disclosure of Participant Payment in Research Recruitment Materials.

Gelinas L, Lynch HF, Largent EA, Shachar C, Cohen IG, Bierer BE.

Ther Innov Regul Sci. 2018 May;52(3):268-274. doi: 10.1177/2168479018770644. Epub 2018 Apr 8.

PMID:
29714586
35.

Population scale retrospective analysis reveals distinctive antidepressant and anxiolytic effects of diclofenac, ketoprofen and naproxen in patients with pain.

Makunts T, Cohen IV, Lee KC, Abagyan R.

PLoS One. 2018 Apr 18;13(4):e0195521. doi: 10.1371/journal.pone.0195521. eCollection 2018.

36.

On Scarcity and the Value of Clinical Trials.

Gelinas L, Lynch HF, Bierer BE, Cohen IG.

Am J Bioeth. 2018 Apr;18(4):71-73. doi: 10.1080/15265161.2018.1444819. No abstract available.

PMID:
29621470
37.

Preventing Mitochondrial Diseases: Embryo-Sparing Donor-Independent Options.

Adashi EY, Cohen IG.

Trends Mol Med. 2018 May;24(5):449-457. doi: 10.1016/j.molmed.2018.03.002. Epub 2018 Mar 28. Review.

PMID:
29605176
38.

Facilitated recruitment of mesenchymal stromal cells by bone marrow concentrate and platelet rich plasma.

Holmes HL, Wilson B, Goerger JP, Silverberg JL, Cohen I, Zipfel WR, Fortier LA.

PLoS One. 2018 Mar 22;13(3):e0194567. doi: 10.1371/journal.pone.0194567. eCollection 2018.

39.

Pre-equilibrium competitive library screening for tuning inhibitor association rate and specificity toward serine proteases.

Cohen I, Naftaly S, Ben-Zeev E, Hockla A, Radisky ES, Papo N.

Biochem J. 2018 Apr 16;475(7):1335-1352. doi: 10.1042/BCJ20180070.

PMID:
29535275
40.

Local and global measurements show that damage initiation in articular cartilage is inhibited by the surface layer and has significant rate dependence.

Bartell LR, Xu MC, Bonassar LJ, Cohen I.

J Biomech. 2018 Apr 27;72:63-70. doi: 10.1016/j.jbiomech.2018.02.033. Epub 2018 Mar 2.

PMID:
29526459
41.

RSRC1 mutation affects intellect and behaviour through aberrant splicing and transcription, downregulating IGFBP3.

Perez Y, Menascu S, Cohen I, Kadir R, Basha O, Shorer Z, Romi H, Meiri G, Rabinski T, Ofir R, Yeger-Lotem E, Birk OS.

Brain. 2018 Apr 1;141(4):961-970. doi: 10.1093/brain/awy045.

PMID:
29522154
42.

Precision Measurement of the β Asymmetry in Spin-Polarized ^{37}K Decay.

Fenker B, Gorelov A, Melconian D, Behr JA, Anholm M, Ashery D, Behling RS, Cohen I, Craiciu I, Gwinner G, McNeil J, Mehlman M, Olchanski K, Shidling PD, Smale S, Warner CL.

Phys Rev Lett. 2018 Feb 9;120(6):062502. doi: 10.1103/PhysRevLett.120.062502.

PMID:
29481259
43.

Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of MMP-9 and MMP-14.

Shirian J, Arkadash V, Cohen I, Sapir T, Radisky ES, Papo N, Shifman JM.

FEBS Lett. 2018 Apr;592(7):1122-1134. doi: 10.1002/1873-3468.13016. Epub 2018 Mar 12.

PMID:
29473954
44.

A Framework for Ethical Payment to Research Participants.

Gelinas L, Largent EA, Cohen IG, Kornetsky S, Bierer BE, Fernandez Lynch H.

N Engl J Med. 2018 Feb 22;378(8):766-771. doi: 10.1056/NEJMsb1710591. No abstract available.

PMID:
29466147
45.

Experimental evidences of 95 mTc production in a nuclear reactor.

Cohen IM, Robles A, Mendoza P, Airas RM, Montoya EH.

Appl Radiat Isot. 2018 May;135:207-211. doi: 10.1016/j.apradiso.2018.02.001. Epub 2018 Feb 2.

PMID:
29427956
46.

Preventing Mitochondrial Disease: A Path Forward.

Adashi EY, Cohen IG.

Obstet Gynecol. 2018 Mar;131(3):553-556. doi: 10.1097/AOG.0000000000002486.

PMID:
29420413
47.

Acetaminophen (Paracetamol) Use Modifies the Sulfation of Sex Hormones.

Cohen IV, Cirulli ET, Mitchell MW, Jonsson TJ, Yu J, Shah N, Spector TD, Guo L, Venter JC, Telenti A.

EBioMedicine. 2018 Feb;28:316-323. doi: 10.1016/j.ebiom.2018.01.033. Epub 2018 Feb 15.

48.

Folate receptor autoantibodies are prevalent in children diagnosed with autism spectrum disorder, their normal siblings and parents.

Quadros EV, Sequeira JM, Brown WT, Mevs C, Marchi E, Flory M, Jenkins EC, Velinov MT, Cohen IL.

Autism Res. 2018 May;11(5):707-712. doi: 10.1002/aur.1934. Epub 2018 Feb 2.

PMID:
29394471
49.

Differential Effects of Formal and Informal Gambling on Symptoms of Problem Gambling During Voluntary Self-Exclusion.

McCormick AV, Cohen IM, Davies G.

J Gambl Stud. 2018 Sep;34(3):1013-1031. doi: 10.1007/s10899-018-9743-5.

PMID:
29349720
50.

Determining Quiescent Colloidal Suspension Viscosities Using the Green-Kubo Relation and Image-Based Stress Measurements.

Lin NYC, Bierbaum M, Cohen I.

Phys Rev Lett. 2017 Sep 29;119(13):138001. doi: 10.1103/PhysRevLett.119.138001. Epub 2017 Sep 27.

PMID:
29341681

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