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Items: 1 to 50 of 144

1.

A Novel Role for GATA3 in Mesangial Cells in Glomerular Development and Injury.

Grigorieva IV, Oszwald A, Grigorieva EF, Schachner H, Neudert B, Ostendorf T, Floege J, Lindenmeyer MT, Cohen CD, Panzer U, Aigner C, Schmidt A, Grosveld F, Thakker RV, Rees AJ, Kain R.

J Am Soc Nephrol. 2019 Sep;30(9):1641-1658. doi: 10.1681/ASN.2018111143. Epub 2019 Aug 12.

PMID:
31405951
2.

Interleukin-1β Inhibition for Chronic Kidney Disease in Obese Mice With Type 2 Diabetes.

Lei Y, Devarapu SK, Motrapu M, Cohen CD, Lindenmeyer MT, Moll S, Kumar SV, Anders HJ.

Front Immunol. 2019 May 29;10:1223. doi: 10.3389/fimmu.2019.01223. eCollection 2019.

3.

BDNF: mRNA expression in urine cells of patients with chronic kidney disease and its role in kidney function.

Endlich N, Lange T, Kuhn J, Klemm P, Kotb AM, Siegerist F, Kindt F, Lindenmeyer MT, Cohen CD, Kuss AW, Nath N, Rettig R, Lendeckel U, Zimmermann U, Amann K, Stracke S, Endlich K.

J Cell Mol Med. 2018 Nov;22(11):5265-5277. doi: 10.1111/jcmm.13762. Epub 2018 Aug 21.

4.

Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury.

Papakrivopoulou E, Vasilopoulou E, Lindenmeyer MT, Pacheco S, Brzóska HŁ, Price KL, Kolatsi-Joannou M, White KE, Henderson DJ, Dean CH, Cohen CD, Salama AD, Woolf AS, Long DA.

J Pathol. 2018 Dec;246(4):485-496. doi: 10.1002/path.5158.

5.

YB-1 increases glomerular, but decreases interstitial fibrosis in CNI-induced nephropathy.

Gibbert L, Hermert D, Wang J, M Breitkopf D, Alidousty C, Neusser M, Cohen CD, Gröne E, Macheleidt I, Rauen T, Braun GS, Floege J, Ostendorf T, Raffetseder U.

Clin Immunol. 2018 Sep;194:67-74. doi: 10.1016/j.clim.2018.07.002. Epub 2018 Jul 3.

PMID:
30018024
6.

Metabolic pathways and immunometabolism in rare kidney diseases.

Grayson PC, Eddy S, Taroni JN, Lightfoot YL, Mariani L, Parikh H, Lindenmeyer MT, Ju W, Greene CS, Godfrey B, Cohen CD, Krischer J, Kretzler M, Merkel PA; Vasculitis Clinical Research Consortium, the European Renal cDNA Bank cohort, and the Nephrotic Syndrome Study Network.

Ann Rheum Dis. 2018 Aug;77(8):1226-1233. doi: 10.1136/annrheumdis-2017-212935. Epub 2018 May 3.

7.

The transcription factor Dach1 is essential for podocyte function.

Endlich N, Kliewe F, Kindt F, Schmidt K, Kotb AM, Artelt N, Lindenmeyer MT, Cohen CD, Döring F, Kuss AW, Amann K, Moeller MJ, Kabgani N, Blumenthal A, Endlich K.

J Cell Mol Med. 2018 May;22(5):2656-2669. doi: 10.1111/jcmm.13544. Epub 2018 Mar 2.

8.

Lymphotoxin expression in human and murine renal allografts.

Seeger H, Lindenmeyer MT, Cohen CD, Jaeckel C, Nelson PJ, Chen J, Edenhofer I, Kozakowski N, Regele H, Boehmig G, Brandt S, Wuethrich RP, Heikenwalder M, Fehr T, Segerer S.

PLoS One. 2018 Jan 4;13(1):e0189396. doi: 10.1371/journal.pone.0189396. eCollection 2018.

9.

Studying the role of fascin-1 in mechanically stressed podocytes.

Kliewe F, Scharf C, Rogge H, Darm K, Lindenmeyer MT, Amann K, Cohen CD, Endlich K, Endlich N.

Sci Rep. 2017 Aug 30;7(1):9916. doi: 10.1038/s41598-017-10116-4.

10.

Transcriptome-based network analysis reveals renal cell type-specific dysregulation of hypoxia-associated transcripts.

Shved N, Warsow G, Eichinger F, Hoogewijs D, Brandt S, Wild P, Kretzler M, Cohen CD, Lindenmeyer MT.

Sci Rep. 2017 Aug 17;7(1):8576. doi: 10.1038/s41598-017-08492-y.

11.

Targeting mTOR Signaling Can Prevent the Progression of FSGS.

Zschiedrich S, Bork T, Liang W, Wanner N, Eulenbruch K, Munder S, Hartleben B, Kretz O, Gerber S, Simons M, Viau A, Burtin M, Wei C, Reiser J, Herbach N, Rastaldi MP, Cohen CD, Tharaux PL, Terzi F, Walz G, Gödel M, Huber TB.

J Am Soc Nephrol. 2017 Jul;28(7):2144-2157. doi: 10.1681/ASN.2016050519. Epub 2017 Mar 7.

12.

Loss of endogenous thymosin β4 accelerates glomerular disease.

Vasilopoulou E, Kolatsi-Joannou M, Lindenmeyer MT, White KE, Robson MG, Cohen CD, Sebire NJ, Riley PR, Winyard PJ, Long DA.

Kidney Int. 2016 Nov;90(5):1056-1070. doi: 10.1016/j.kint.2016.06.032. Epub 2016 Aug 26.

13.

The Authors Reply.

Segerer S, Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Cohen CD, Neuhauss SCF, Loffing J.

Kidney Int. 2016 May;89(5):1161-1162. doi: 10.1016/j.kint.2015.10.020. No abstract available.

PMID:
27083290
14.

Urinary Soluble CD163 in Active Renal Vasculitis.

O'Reilly VP, Wong L, Kennedy C, Elliot LA, O'Meachair S, Coughlan AM, O'Brien EC, Ryan MM, Sandoval D, Connolly E, Dekkema GJ, Lau J, Abdulahad WH, Sanders JS, Heeringa P, Buckley C, O'Brien C, Finn S, Cohen CD, Lindemeyer MT, Hickey FB, O'Hara PV, Feighery C, Moran SM, Mellotte G, Clarkson MR, Dorman AJ, Murray PT, Little MA.

J Am Soc Nephrol. 2016 Sep;27(9):2906-16. doi: 10.1681/ASN.2015050511. Epub 2016 Mar 3. Erratum in: J Am Soc Nephrol. 2018 Aug;29(8):2255.

15.

Keratins are novel markers of renal epithelial cell injury.

Djudjaj S, Papasotiriou M, Bülow RD, Wagnerova A, Lindenmeyer MT, Cohen CD, Strnad P, Goumenos DS, Floege J, Boor P.

Kidney Int. 2016 Apr;89(4):792-808. doi: 10.1016/j.kint.2015.10.015. Epub 2016 Feb 6.

PMID:
26924053
16.

Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker.

Ju W, Nair V, Smith S, Zhu L, Shedden K, Song PXK, Mariani LH, Eichinger FH, Berthier CC, Randolph A, Lai JY, Zhou Y, Hawkins JJ, Bitzer M, Sampson MG, Thier M, Solier C, Duran-Pacheco GC, Duchateau-Nguyen G, Essioux L, Schott B, Formentini I, Magnone MC, Bobadilla M, Cohen CD, Bagnasco SM, Barisoni L, Lv J, Zhang H, Wang HY, Brosius FC, Gadegbeku CA, Kretzler M; ERCB, C-PROBE, NEPTUNE, and PKU-IgAN Consortium.

Sci Transl Med. 2015 Dec 2;7(316):316ra193. doi: 10.1126/scitranslmed.aac7071.

17.

Cathepsin S Cleavage of Protease-Activated Receptor-2 on Endothelial Cells Promotes Microvascular Diabetes Complications.

Kumar Vr S, Darisipudi MN, Steiger S, Devarapu SK, Tato M, Kukarni OP, Mulay SR, Thomasova D, Popper B, Demleitner J, Zuchtriegel G, Reichel C, Cohen CD, Lindenmeyer MT, Liapis H, Moll S, Reid E, Stitt AW, Schott B, Gruner S, Haap W, Ebeling M, Hartmann G, Anders HJ.

J Am Soc Nephrol. 2016 Jun;27(6):1635-49. doi: 10.1681/ASN.2015020208. Epub 2015 Nov 13.

18.

Macrophage Migration Inhibitory Factor Mediates Proliferative GN via CD74.

Djudjaj S, Lue H, Rong S, Papasotiriou M, Klinkhammer BM, Zok S, Klaener O, Braun GS, Lindenmeyer MT, Cohen CD, Bucala R, Tittel AP, Kurts C, Moeller MJ, Floege J, Ostendorf T, Bernhagen J, Boor P.

J Am Soc Nephrol. 2016 Jun;27(6):1650-64. doi: 10.1681/ASN.2015020149. Epub 2015 Oct 9.

19.

The lymphotoxin β receptor is a potential therapeutic target in renal inflammation.

Seleznik G, Seeger H, Bauer J, Fu K, Czerkowicz J, Papandile A, Poreci U, Rabah D, Ranger A, Cohen CD, Lindenmeyer M, Chen J, Edenhofer I, Anders HJ, Lech M, Wüthrich RP, Ruddle NH, Moeller MJ, Kozakowski N, Regele H, Browning JL, Heikenwalder M, Segerer S.

Kidney Int. 2016 Jan;89(1):113-26. doi: 10.1038/ki.2015.280. Epub 2016 Jan 4.

PMID:
26398497
20.

The Rho-GTPase binding protein IQGAP2 is required for the glomerular filtration barrier.

Sugano Y, Lindenmeyer MT, Auberger I, Ziegler U, Segerer S, Cohen CD, Neuhauss SC, Loffing J.

Kidney Int. 2015 Nov;88(5):1047-56. doi: 10.1038/ki.2015.197. Epub 2015 Jul 8.

PMID:
26154927
21.

Destruction of a distal hypoxia response element abolishes trans-activation of the PAG1 gene mediated by HIF-independent chromatin looping.

Schörg A, Santambrogio S, Platt JL, Schödel J, Lindenmeyer MT, Cohen CD, Schrödter K, Mole DR, Wenger RH, Hoogewijs D.

Nucleic Acids Res. 2015 Jul 13;43(12):5810-23. doi: 10.1093/nar/gkv506. Epub 2015 May 24.

22.

[Prognosis and therapy of inflammatory rheumatic diseases : Impact of renal manifestations].

Zänker M, Cohen CD, Rupprecht HD.

Z Rheumatol. 2015 May;74(4):310-21. doi: 10.1007/s00393-014-1479-8. Review. German.

PMID:
25962452
23.

BAMBI elimination enhances alternative TGF-β signaling and glomerular dysfunction in diabetic mice.

Fan Y, Li X, Xiao W, Fu J, Harris RC, Lindenmeyer M, Cohen CD, Guillot N, Baron MH, Wang N, Lee K, He JC, Schlondorff D, Chuang PY.

Diabetes. 2015 Jun;64(6):2220-33. doi: 10.2337/db14-1397. Epub 2015 Jan 9.

24.

Integrative biology identifies shared transcriptional networks in CKD.

Martini S, Nair V, Keller BJ, Eichinger F, Hawkins JJ, Randolph A, Böger CA, Gadegbeku CA, Fox CS, Cohen CD, Kretzler M; European Renal cDNA Bank; C-PROBE Cohort; CKDGen Consortium.

J Am Soc Nephrol. 2014 Nov;25(11):2559-72. doi: 10.1681/ASN.2013080906. Epub 2014 Jun 12.

25.

Alterations in the ubiquitin proteasome system in persistent but not reversible proteinuric diseases.

Beeken M, Lindenmeyer MT, Blattner SM, Radón V, Oh J, Meyer TN, Hildebrand D, Schlüter H, Reinicke AT, Knop JH, Vivekanandan-Giri A, Münster S, Sachs M, Wiech T, Pennathur S, Cohen CD, Kretzler M, Stahl RA, Meyer-Schwesinger C.

J Am Soc Nephrol. 2014 Nov;25(11):2511-25. doi: 10.1681/ASN.2013050522. Epub 2014 Apr 10.

26.

Mpv17 in mitochondria protects podocytes against mitochondrial dysfunction and apoptosis in vivo and in vitro.

Casalena G, Krick S, Daehn I, Yu L, Ju W, Shi S, Tsai SY, D'Agati V, Lindenmeyer M, Cohen CD, Schlondorff D, Bottinger EP.

Am J Physiol Renal Physiol. 2014 Jun 1;306(11):F1372-80. doi: 10.1152/ajprenal.00608.2013. Epub 2014 Mar 5.

27.

UCH-L1 induces podocyte hypertrophy in membranous nephropathy by protein accumulation.

Lohmann F, Sachs M, Meyer TN, Sievert H, Lindenmeyer MT, Wiech T, Cohen CD, Balabanov S, Stahl RA, Meyer-Schwesinger C.

Biochim Biophys Acta. 2014 Jul;1842(7):945-58. doi: 10.1016/j.bbadis.2014.02.011. Epub 2014 Feb 28.

28.

[Caplan's syndrome: rarely presenting as <<pulmorenal>> syndrome].

Nowak A, Göhner K, Cohen CD.

Praxis (Bern 1994). 2014 Feb 26;103(5):279-84. doi: 10.1024/1661-8157/a001573. German.

PMID:
24568764
29.

Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease.

Dessapt-Baradez C, Woolf AS, White KE, Pan J, Huang JL, Hayward AA, Price KL, Kolatsi-Joannou M, Locatelli M, Diennet M, Webster Z, Smillie SJ, Nair V, Kretzler M, Cohen CD, Long DA, Gnudi L.

J Am Soc Nephrol. 2014 Jan;25(1):33-42. doi: 10.1681/ASN.2012121218. Epub 2013 Sep 5.

30.

Defining cell-type specificity at the transcriptional level in human disease.

Ju W, Greene CS, Eichinger F, Nair V, Hodgin JB, Bitzer M, Lee YS, Zhu Q, Kehata M, Li M, Jiang S, Rastaldi MP, Cohen CD, Troyanskaya OG, Kretzler M.

Genome Res. 2013 Nov;23(11):1862-73. doi: 10.1101/gr.155697.113. Epub 2013 Aug 15.

31.

Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease.

Sharma K, Karl B, Mathew AV, Gangoiti JA, Wassel CL, Saito R, Pu M, Sharma S, You YH, Wang L, Diamond-Stanic M, Lindenmeyer MT, Forsblom C, Wu W, Ix JH, Ideker T, Kopp JB, Nigam SK, Cohen CD, Groop PH, Barshop BA, Natarajan L, Nyhan WL, Naviaux RK.

J Am Soc Nephrol. 2013 Nov;24(11):1901-12. doi: 10.1681/ASN.2013020126. Epub 2013 Oct 10.

32.

Susceptibility of podocytes to palmitic acid is regulated by stearoyl-CoA desaturases 1 and 2.

Sieber J, Weins A, Kampe K, Gruber S, Lindenmeyer MT, Cohen CD, Orellana JM, Mundel P, Jehle AW.

Am J Pathol. 2013 Sep;183(3):735-44. doi: 10.1016/j.ajpath.2013.05.023. Epub 2013 Jul 16.

33.

Periostin: a matricellular protein involved in peritoneal injury during peritoneal dialysis.

Braun N, Sen K, Alscher MD, Fritz P, Kimmel M, Morelle J, Goffin E, Jörres A, Wüthrich RP, Cohen CD, Segerer S.

Perit Dial Int. 2013 Sep-Oct;33(5):515-28. doi: 10.3747/pdi.2010.00259. Epub 2013 Feb 1.

34.

The spectrum of podoplanin expression in encapsulating peritoneal sclerosis.

Braun N, Alscher MD, Fritz P, Latus J, Edenhofer I, Reimold F, Alper SL, Kimmel M, Biegger D, Lindenmeyer M, Cohen CD, Wüthrich RP, Segerer S.

PLoS One. 2012;7(12):e53382. doi: 10.1371/journal.pone.0053382. Epub 2012 Dec 31.

35.

Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation.

van Roeyen CR, Zok S, Pruessmeyer J, Boor P, Nagayama Y, Fleckenstein S, Cohen CD, Eitner F, Gröne HJ, Ostendorf T, Ludwig A, Floege J.

Kidney Int. 2013 Feb;83(2):251-63. doi: 10.1038/ki.2012.400. Epub 2012 Dec 19.

36.

Kidney diseases caused by complement dysregulation: acquired, inherited, and still more to come.

Heeringa SF, Cohen CD.

Clin Dev Immunol. 2012;2012:695131. doi: 10.1155/2012/695131. Epub 2012 Nov 14. Review.

37.

Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms.

Villa L, Boor P, Konieczny A, Kunter U, van Roeyen CR, Denecke B, Gan L, Neusser MA, Cohen CD; ERCB Consortium;, Eitner F, Scholl T, Ostendorf T, Floege J.

J Pathol. 2013 Apr;229(5):672-84. doi: 10.1002/path.4151. Epub 2013 Mar 5.

PMID:
23192593
38.

Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury.

Djudjaj S, Chatziantoniou C, Raffetseder U, Guerrot D, Dussaule JC, Boor P, Kerroch M, Hanssen L, Brandt S, Dittrich A, Ostendorf T, Floege J, Zhu C, Lindenmeyer M, Cohen CD, Mertens PR.

J Pathol. 2012 Nov;228(3):286-99. doi: 10.1002/path.4076. Epub 2012 Sep 7.

PMID:
22806125
39.

Cross-species transcriptional network analysis defines shared inflammatory responses in murine and human lupus nephritis.

Berthier CC, Bethunaickan R, Gonzalez-Rivera T, Nair V, Ramanujam M, Zhang W, Bottinger EP, Segerer S, Lindenmeyer M, Cohen CD, Davidson A, Kretzler M.

J Immunol. 2012 Jul 15;189(2):988-1001. doi: 10.4049/jimmunol.1103031. Epub 2012 Jun 20.

40.

Next-generation sequencing identifies TGF-β1-associated gene expression profiles in renal epithelial cells reiterated in human diabetic nephropathy.

Brennan EP, Morine MJ, Walsh DW, Roxburgh SA, Lindenmeyer MT, Brazil DP, Gaora PÓ, Roche HM, Sadlier DM, Cohen CD; GENIE Consortium, Godson C, Martin F.

Biochim Biophys Acta. 2012 Apr;1822(4):589-99. doi: 10.1016/j.bbadis.2012.01.008. Epub 2012 Jan 14.

41.

Bcl-2-modifying factor induces renal proximal tubular cell apoptosis in diabetic mice.

Lau GJ, Godin N, Maachi H, Lo CS, Wu SJ, Zhu JX, Brezniceanu ML, Chénier I, Fragasso-Marquis J, Lattouf JB, Ethier J, Filep JG, Ingelfinger JR, Nair V, Kretzler M, Cohen CD, Zhang SL, Chan JS.

Diabetes. 2012 Feb;61(2):474-84. doi: 10.2337/db11-0141. Epub 2011 Dec 30.

42.

Predicting an allograft's fate.

Fehr T, Cohen CD.

Kidney Int. 2011 Dec;80(12):1254-5. doi: 10.1038/ki.2011.328.

43.

Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus.

Kahlenberg JM, Thacker SG, Berthier CC, Cohen CD, Kretzler M, Kaplan MJ.

J Immunol. 2011 Dec 1;187(11):6143-56. doi: 10.4049/jimmunol.1101284. Epub 2011 Nov 4.

44.

Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.

Lichtnekert J, Kulkarni OP, Mulay SR, Rupanagudi KV, Ryu M, Allam R, Vielhauer V, Muruve D, Lindenmeyer MT, Cohen CD, Anders HJ.

PLoS One. 2011;6(10):e26778. doi: 10.1371/journal.pone.0026778. Epub 2011 Oct 27.

45.

Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy.

Ribeiro A, Wörnle M, Motamedi N, Anders HJ, Gröne EF, Nitschko H, Kurktschiev P, Debiec H, Kretzler M, Cohen CD, Gröne HJ, Schlöndorff D, Schmid H.

Kidney Int. 2012 Jan;81(1):100-11. doi: 10.1038/ki.2011.311. Epub 2011 Sep 14.

46.

Alteration of forkhead box O (foxo4) acetylation mediates apoptosis of podocytes in diabetes mellitus.

Chuang PY, Dai Y, Liu R, He H, Kretzler M, Jim B, Cohen CD, He JC.

PLoS One. 2011;6(8):e23566. doi: 10.1371/journal.pone.0023566. Epub 2011 Aug 17.

47.

Periostin is induced in glomerular injury and expressed de novo in interstitial renal fibrosis.

Sen K, Lindenmeyer MT, Gaspert A, Eichinger F, Neusser MA, Kretzler M, Segerer S, Cohen CD.

Am J Pathol. 2011 Oct;179(4):1756-67. doi: 10.1016/j.ajpath.2011.06.002. Epub 2011 Aug 18.

48.

Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome.

Etter C, Gaspert A, Regenass S, Wüthrich RP, Kistler T, Kain R, Cohen CD.

BMC Nephrol. 2011 Jun 8;12:26. doi: 10.1186/1471-2369-12-26.

49.

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.

Gödel M, Hartleben B, Herbach N, Liu S, Zschiedrich S, Lu S, Debreczeni-Mór A, Lindenmeyer MT, Rastaldi MP, Hartleben G, Wiech T, Fornoni A, Nelson RG, Kretzler M, Wanke R, Pavenstädt H, Kerjaschki D, Cohen CD, Hall MN, Rüegg MA, Inoki K, Walz G, Huber TB.

J Clin Invest. 2011 Jun;121(6):2197-209. doi: 10.1172/JCI44774. Epub 2011 May 23.

50.

The role of bone morphogenetic protein-5 (BMP-5) in human nephrosclerosis.

Bramlage CP, Müller GA, Tampe B, Bevanda J, Maatouk I, Koziolek M, Lange K, Ahrens K, Schmid H, Cohen CD, Bramlage P, Kretzler M, Strutz F.

J Nephrol. 2011 Sep-Oct;24(5):647-55. doi: 10.5301/JN.2011.6330.

PMID:
21319131

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