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Items: 44

1.

Isolation of Nile crocodile (Crocodylus niloticus) serum immunoglobulin M and Y (IgM and IgY).

Shaik Abdool F, Coetzer THT, Goldring JPD.

J Immunol Methods. 2019 Dec 16:112724. doi: 10.1016/j.jim.2019.112724. [Epub ahead of print]

PMID:
31837304
2.

Expression and copper binding properties of the N-terminal domain of copper P-type ATPases of African trypanosomes.

Isah MB, Goldring JPD, Coetzer THT.

Mol Biochem Parasitol. 2020 Jan;235:111245. doi: 10.1016/j.molbiopara.2019.111245. Epub 2019 Nov 18.

PMID:
31751595
3.

Expression, purification and characterisation of Trypanosoma congolense metacaspase 5 (TcoMCA5) - a potential drug target for animal African trypanosomiasis.

Eyssen LE, Coetzer THT.

Protein Expr Purif. 2019 Dec;164:105465. doi: 10.1016/j.pep.2019.105465. Epub 2019 Aug 1.

PMID:
31377239
4.

Recombinant and native TviCATL from Trypanosoma vivax: Enzymatic characterisation and evaluation as a diagnostic target for animal African trypanosomosis.

Eyssen LE, Vather P, Jackson L, Ximba P, Biteau N, Baltz T, Boulangé A, Büscher P, Coetzer THT.

Mol Biochem Parasitol. 2018 Jul;223:50-54. doi: 10.1016/j.molbiopara.2018.07.001. Epub 2018 Jul 7.

PMID:
29990512
5.

Plasmodium glyceraldehyde-3-phosphate dehydrogenase: A potential malaria diagnostic target.

Krause RGE, Hurdayal R, Choveaux D, Przyborski JM, Coetzer THT, Goldring JPD.

Exp Parasitol. 2017 Aug;179:7-19. doi: 10.1016/j.exppara.2017.05.007. Epub 2017 May 26.

PMID:
28552792
6.

A systematic review of pentacyclic triterpenes and their derivatives as chemotherapeutic agents against tropical parasitic diseases.

Isah MB, Ibrahim MA, Mohammed A, Aliyu AB, Masola B, Coetzer TH.

Parasitology. 2016 Sep;143(10):1219-31. doi: 10.1017/S0031182016000718. Epub 2016 May 31. Review.

PMID:
27240847
7.

The Drosophila retinoblastoma binding protein 6 family member has two isoforms and is potentially involved in embryonic patterning.

Hull R, Oosthuysen B, Cajee UF, Mokgohloa L, Nweke E, Antunes RJ, Coetzer TH, Ntwasa M.

Int J Mol Sci. 2015 May 6;16(5):10242-66. doi: 10.3390/ijms160510242.

8.

Phylogenetic analysis of the polyprotein coding region of an infectious South African bursal disease virus (IBDV) strain.

Vukea PR, Willows-Munro S, Horner RF, Coetzer TH.

Infect Genet Evol. 2014 Jan;21:279-86. doi: 10.1016/j.meegid.2013.11.017. Epub 2013 Dec 1.

PMID:
24291011
9.

Recombinant expression and biochemical characterisation of two alanyl aminopeptidases of Trypanosoma congolense.

Pillay D, Boulangé AF, Coustou V, Baltz T, Coetzer TH.

Exp Parasitol. 2013 Dec;135(4):675-84. doi: 10.1016/j.exppara.2013.10.005. Epub 2013 Oct 28.

PMID:
24177338
10.

The x-ray crystal structure of mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) syndrome.

Yongqing T, Wilmann PG, Reeve SB, Coetzer TH, Smith AI, Whisstock JC, Pike RN, Wijeyewickrema LC.

J Biol Chem. 2013 Aug 2;288(31):22399-407. doi: 10.1074/jbc.M113.483875. Epub 2013 Jun 21. Erratum in: J Biol Chem. 2013 Sep 27;288(39):28307.

11.

Molecular determinants of the substrate specificity of the complement-initiating protease, C1r.

Wijeyewickrema LC, Yongqing T, Tran TP, Thompson PE, Viljoen JE, Coetzer TH, Duncan RC, Kass I, Buckle AM, Pike RN.

J Biol Chem. 2013 May 31;288(22):15571-80. doi: 10.1074/jbc.M113.451757. Epub 2013 Apr 15.

12.

Identification of a catalytic exosite for complement component C4 on the serine protease domain of C1s.

Duncan RC, Mohlin F, Taleski D, Coetzer TH, Huntington JA, Payne RJ, Blom AM, Pike RN, Wijeyewickrema LC.

J Immunol. 2012 Sep 1;189(5):2365-73. doi: 10.4049/jimmunol.1201085. Epub 2012 Aug 1.

13.

Effect of adjuvants on the humoral immune response to congopain in mice and cattle.

Kateregga J, Lubega GW, Lindblad EB, Authié E, Coetzer TH, Boulangé AF.

BMC Vet Res. 2012 May 23;8:63. doi: 10.1186/1746-6148-8-63.

14.

Trypanosoma brucei brucei oligopeptidase B null mutants display increased prolyl oligopeptidase-like activity.

Kangethe RT, Boulangé AF, Coustou V, Baltz T, Coetzer TH.

Mol Biochem Parasitol. 2012 Mar-Apr;182(1-2):7-16. doi: 10.1016/j.molbiopara.2011.11.007. Epub 2011 Nov 22.

PMID:
22123425
15.

Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4.

Duncan RC, Bergström F, Coetzer TH, Blom AM, Wijeyewickrema LC, Pike RN.

Mol Immunol. 2012 Jan;49(4):593-600. doi: 10.1016/j.molimm.2011.10.006. Epub 2011 Nov 8.

PMID:
22071314
16.

Production of congopain, the major cysteine protease of Trypanosoma (Nannomonas) congolense, in Pichia pastoris reveals unexpected dimerisation at physiological pH.

Boulangé AF, Khamadi SA, Pillay D, Coetzer TH, Authié E.

Protein Expr Purif. 2011 Jan;75(1):95-103. doi: 10.1016/j.pep.2010.09.002. Epub 2010 Sep 7.

PMID:
20828616
17.

Expression, purification and characterisation of two variant cysteine peptidases from Trypanosoma congolense with active site substitutions.

Pillay D, Boulangé AF, Coetzer TH.

Protein Expr Purif. 2010 Dec;74(2):264-71. doi: 10.1016/j.pep.2010.06.021. Epub 2010 Jul 4.

PMID:
20609389
18.

Anti-peptide antibodies differentiate between plasmodial lactate dehydrogenases.

Hurdayal R, Achilonu I, Choveaux D, Coetzer TH, Dean Goldring JP.

Peptides. 2010 Apr;31(4):525-32. doi: 10.1016/j.peptides.2010.01.002. Epub 2010 Jan 20.

PMID:
20093160
19.

Modulation of the immunogenicity of the Trypanosoma congolense cysteine protease, congopain, through complexation with alpha(2)-macroglobulin.

Huson LE, Authié E, Boulangé AF, Goldring JP, Coetzer TH.

Vet Res. 2009 Nov-Dec;40(6):52. doi: 10.1051/vetres/2009036. Epub 2009 Jun 24.

20.

A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites.

Beckham SA, Piedrafita D, Phillips CI, Samarawickrema N, Law RH, Smooker PM, Quinsey NS, Irving JA, Greenwood D, Verhelst SH, Bogyo M, Turk B, Coetzer TH, Wijeyewickrema LC, Spithill TW, Pike RN.

Int J Biochem Cell Biol. 2009 Jul;41(7):1601-12. doi: 10.1016/j.biocel.2009.02.003. Epub 2009 Feb 20.

21.

Oligopeptidase B: a processing peptidase involved in pathogenesis.

Coetzer TH, Goldring JP, Huson LE.

Biochimie. 2008 Feb;90(2):336-44. Epub 2007 Nov 1. Review.

PMID:
18029266
22.

Raising antibodies in chickens against primaquine, pyrimethamine, dapsone, tetracycline, and doxycycline.

Goldring JP, Thobakgale C, Hiltunen T, Coetzer TH.

Immunol Invest. 2005;34(1):101-14.

PMID:
15773575
23.

Evidence that serpin architecture intrinsically supports papain-like cysteine protease inhibition: engineering alpha(1)-antitrypsin to inhibit cathepsin proteases.

Irving JA, Pike RN, Dai W, Brömme D, Worrall DM, Silverman GA, Coetzer TH, Dennison C, Bottomley SP, Whisstock JC.

Biochemistry. 2002 Apr 16;41(15):4998-5004.

PMID:
11939796
24.

Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation.

Irving JA, Shushanov SS, Pike RN, Popova EY, Brömme D, Coetzer TH, Bottomley SP, Boulynko IA, Grigoryev SA, Whisstock JC.

J Biol Chem. 2002 Apr 12;277(15):13192-201. Epub 2002 Jan 30.

25.

Trypanosome-derived oligopeptidase B is released into the plasma of infected rodents, where it persists and retains full catalytic activity.

Morty RE, Lonsdale-Eccles JD, Mentele R, Auerswald EA, Coetzer TH.

Infect Immun. 2001 Apr;69(4):2757-61.

26.

Chalcone, acyl hydrazide, and related amides kill cultured Trypanosoma brucei brucei.

Troeberg L, Chen X, Flaherty TM, Morty RE, Cheng M, Hua H, Springer C, McKerrow JH, Kenyon GL, Lonsdale-Eccles JD, Coetzer TH, Cohen FE.

Mol Med. 2000 Aug;6(8):660-9.

27.

Characterisation of the antitrypanosomal activity of peptidyl alpha-aminoalkyl phosphonate diphenyl esters.

Morty RE, Troeberg L, Powers JC, Ono S, Lonsdale-Eccles JD, Coetzer TH.

Biochem Pharmacol. 2000 Nov 15;60(10):1497-504.

PMID:
11020452
28.

Purification and characterisation of a trypsin-like serine oligopeptidase from Trypanosoma congolense.

Morty RE, Authié E, Troeberg L, Lonsdale-Eccles JD, Coetzer TH.

Mol Biochem Parasitol. 1999 Jul 30;102(1):145-55.

PMID:
10477183
29.

Oligopeptidase B from Trypanosoma brucei, a new member of an emerging subgroup of serine oligopeptidases.

Morty RE, Lonsdale-Eccles JD, Morehead J, Caler EV, Mentele R, Auerswald EA, Coetzer TH, Andrews NW, Burleigh BA.

J Biol Chem. 1999 Sep 10;274(37):26149-56.

30.

Cysteine proteinase inhibitors kill cultured bloodstream forms of Trypanosoma brucei brucei.

Troeberg L, Morty RE, Pike RN, Lonsdale-Eccles JD, Palmer JT, McKerrow JH, Coetzer TH.

Exp Parasitol. 1999 Apr;91(4):349-55.

PMID:
10092479
31.

A trypanosome oligopeptidase as a target for the trypanocidal agents pentamidine, diminazene and suramin.

Morty RE, Troeberg L, Pike RN, Jones R, Nickel P, Lonsdale-Eccles JD, Coetzer TH.

FEBS Lett. 1998 Aug 21;433(3):251-6.

32.
33.

Characterization of a multicatalytic proteinase complex (20S proteasome) from Trypanosoma brucei brucei.

Lomo PO, Coetzer TH, Lonsdale-Eccles JD.

Immunopharmacology. 1997 Jun;36(2-3):285-93.

PMID:
9228559
34.

Localisation of acid phosphatase activity on the surface of bloodstream forms of Trypanosoma congolense.

Tosomba OM, Coetzer TH, Lonsdale-Eccles JD.

Exp Parasitol. 1996 Dec;84(3):429-38.

PMID:
8948332
35.

Proteases from Trypanosoma brucei brucei. Purification, characterisation and interactions with host regulatory molecules.

Troeberg L, Pike RN, Morty RE, Berry RK, Coetzer TH, Lonsdale-Eccles JD.

Eur J Biochem. 1996 Jun 15;238(3):728-36.

36.

The amino acid sequences, structure comparisons and inhibition kinetics of sheep cathepsin L and sheep stefin B.

Ritonja A, Coetzer TH, Pike RN, Dennison C.

Comp Biochem Physiol B Biochem Mol Biol. 1996 Jun;114(2):193-8.

PMID:
8759291
37.

Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis.

Pike RN, Potempa J, McGraw W, Coetzer TH, Travis J.

J Bacteriol. 1996 May;178(10):2876-82.

38.

Mature cathepsin L is substantially active in the ionic milieu of the extracellular medium.

Dehrmann FM, Coetzer TH, Pike RN, Dennison C.

Arch Biochem Biophys. 1995 Dec 1;324(1):93-8.

PMID:
7503566
39.

Baboon (Papio ursinus) cathepsin L: purification, characterization and comparison with human and sheep cathepsin L.

Coetzer TH, Dennehy KM, Pike RN, Dennison C.

Comp Biochem Physiol B Biochem Mol Biol. 1995 Nov;112(3):429-39.

PMID:
8529021
40.

NAD (V-factor)-independent and typical Haemophilus paragallinarum infection in commercial chickens: a five year field study.

Horner RF, Bishop GC, Jarvis CJ, Coetzer TH.

Avian Pathol. 1995 Sep;24(3):453-63.

PMID:
18645802
41.

Localization of an immunoinhibitory epitope of the cysteine proteinase, cathepsin L.

Coetzer TH, Pike RN, Dennison C.

Immunol Invest. 1992 Oct;21(6):495-506.

PMID:
1385322
42.
43.

Anti-peptide antibodies to cathepsins B, L and D and type IV collagenase. Specific recognition and inhibition of the enzymes.

Coetzer TH, Elliott E, Fortgens PH, Pike RN, Dennison C.

J Immunol Methods. 1991 Feb 15;136(2):199-210.

PMID:
1847962
44.

An enzyme immunoassay for atractyloside, the nephrotoxin of Callilepis laureola (Impila).

Bye SN, Coetzer TH, Dutton MF.

Toxicon. 1990;28(8):997-1000.

PMID:
2080521

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