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Items: 1 to 50 of 98

1.

New irreversible α-L-iduronidase inhibitors and activity-based probes.

Artola M, Kuo CL, McMahon SA, Oehler V, Hansen T, van der Lienden M, He X, van den Elst H, Florea BI, Kermode AR, Gloster TM, van der Marel GA, Codée JDC, Overkleeft HS, Aerts JMFG.

Chemistry. 2018 Oct 11. doi: 10.1002/chem.201804662. [Epub ahead of print]

PMID:
30307091
2.

Fast and pH-Independent Elimination of trans-Cyclooctene by Using Aminoethyl-Functionalized Tetrazines.

Sarris AJC, Hansen T, de Geus MAR, Maurits E, Doelman W, Overkleeft HS, Codée JDC, Filippov DV, van Kasteren SI.

Chemistry. 2018 Sep 5. doi: 10.1002/chem.201803839. [Epub ahead of print]

PMID:
30184286
3.

Two-step activity-based protein profiling of diacylglycerol lipase.

van Rooden EJ, Kreekel R, Hansen T, Janssen APA, van Esbroeck ACM, den Dulk H, van den Berg RJBHN, Codée JDC, van der Stelt M.

Org Biomol Chem. 2018 Jul 25;16(29):5250-5253. doi: 10.1039/c8ob01499j.

PMID:
30004552
4.

Spiro-epoxyglycosides as Activity-Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase.

Schröder SP, Kallemeijn WW, Debets MF, Hansen T, Sobala LF, Hakki Z, Williams SJ, Beenakker TJM, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS.

Chemistry. 2018 Jul 11;24(39):9983-9992. doi: 10.1002/chem.201801902. Epub 2018 Jun 21.

5.

Formation of Immune Complexes with a Tetanus-Derived B Cell Epitope Boosts Human T Cell Responses to Covalently Linked Peptides in an Ex Vivo Blood Loop System.

Fletcher EAK, van Maren W, Cordfunke R, Dinkelaar J, Codee JDC, van der Marel G, Melief CJM, Ossendorp F, Drijfhout JW, Mangsbo SM.

J Immunol. 2018 Jul 1;201(1):87-97. doi: 10.4049/jimmunol.1700911. Epub 2018 May 11.

PMID:
29752315
6.

Mapping the Relationship between Glycosyl Acceptor Reactivity and Glycosylation Stereoselectivity.

van der Vorm S, van Hengst JMA, Bakker M, Overkleeft HS, van der Marel GA, Codée JDC.

Angew Chem Int Ed Engl. 2018 Jul 2;57(27):8240-8244. doi: 10.1002/anie.201802899. Epub 2018 Apr 26.

7.

Gluco-1 H-imidazole: A New Class of Azole-Type β-Glucosidase Inhibitor.

Schröder SP, Wu L, Artola M, Hansen T, Offen WA, Ferraz MJ, Li KY, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS.

J Am Chem Soc. 2018 Apr 18;140(15):5045-5048. doi: 10.1021/jacs.8b02399. Epub 2018 Apr 4.

8.

Reagent Controlled Stereoselective Synthesis of α-Glucans.

Wang L, Overkleeft HS, van der Marel GA, Codée JDC.

J Am Chem Soc. 2018 Apr 4;140(13):4632-4638. doi: 10.1021/jacs.8b00669. Epub 2018 Mar 23.

9.

Streamlined Synthesis and Evaluation of Teichoic Acid Fragments.

van der Es D, Berni F, Hogendorf WFJ, Meeuwenoord N, Laverde D, van Diepen A, Overkleeft HS, Filippov DV, Hokke CH, Huebner J, van der Marel GA, Codée JDC.

Chemistry. 2018 Mar 15;24(16):4014-4018. doi: 10.1002/chem.201800153. Epub 2018 Feb 19.

10.

Linking T cell epitopes to a common linear B cell epitope: A targeting and adjuvant strategy to improve T cell responses.

Mangsbo SM, Fletcher EAK, van Maren WWC, Redeker A, Cordfunke RA, Dillmann I, Dinkelaar J, Ouchaou K, Codee JDC, van der Marel GA, Hoogerhout P, Melief CJM, Ossendorp F, Drijfhout JW.

Mol Immunol. 2018 Jan;93:115-124. doi: 10.1016/j.molimm.2017.11.004. Epub 2017 Nov 22.

PMID:
29175591
11.

Cyanopivaloyl Ester in the Automated Solid-Phase Synthesis of Oligorhamnans.

Geert Volbeda A, van Mechelen J, Meeuwenoord N, Overkleeft HS, van der Marel GA, Codée JDC.

J Org Chem. 2017 Dec 15;82(24):12992-13002. doi: 10.1021/acs.joc.7b02511. Epub 2017 Dec 1.

12.

Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.

Schröder SP, van de Sande JW, Kallemeijn WW, Kuo CL, Artola M, van Rooden EJ, Jiang J, Beenakker TJM, Florea BI, Offen WA, Davies GJ, Minnaard AJ, Aerts JMFG, Codée JDC, van der Marel GA, Overkleeft HS.

Chem Commun (Camb). 2017 Nov 21;53(93):12528-12531. doi: 10.1039/c7cc07730k.

PMID:
29116266
13.

Synthetic zwitterionic polysaccharides.

Zhang Q, Overkleeft HS, van der Marel GA, Codée JD.

Curr Opin Chem Biol. 2017 Oct;40:95-101. doi: 10.1016/j.cbpa.2017.07.010. Epub 2017 Sep 7. Review.

PMID:
28888143
14.

Chemical synthesis of guanosine diphosphate mannuronic acid (GDP-ManA) and its C-4-O-methyl and C-4-deoxy congeners.

Zhang Q, Howell PL, Overkleeft HS, Filippov DV, van der Marel GA, Codée JDC.

Carbohydr Res. 2017 Oct 10;450:12-18. doi: 10.1016/j.carres.2017.08.005. Epub 2017 Aug 11.

PMID:
28822279
15.

1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor.

Artola M, Wu L, Ferraz MJ, Kuo CL, Raich L, Breen IZ, Offen WA, Codée JDC, van der Marel GA, Rovira C, Aerts JMFG, Davies GJ, Overkleeft HS.

ACS Cent Sci. 2017 Jul 26;3(7):784-793. doi: 10.1021/acscentsci.7b00214. Epub 2017 Jul 13.

16.

Correction to "Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes".

Jiang J, Kuo CL, Wu L, Franke C, Kallemeijn WW, Florea BI, van Meel E, van der Marel GA, Codée JDC, Boot RG, Davies GJ, Overkleeft HS, Aerts JMFG.

ACS Cent Sci. 2017 Jun 28;3(6):673. doi: 10.1021/acscentsci.7b00185. Epub 2017 May 18.

17.

Structural Characterization of Biofunctionalized Gold Nanoparticles by Ultrahigh-Resolution Mass Spectrometry.

Nicolardi S, van der Burgt YEM, Codée JDC, Wuhrer M, Hokke CH, Chiodo F.

ACS Nano. 2017 Aug 22;11(8):8257-8264. doi: 10.1021/acsnano.7b03402. Epub 2017 Jul 12.

18.

Activity-based probes for functional interrogation of retaining β-glucuronidases.

Wu L, Jiang J, Jin Y, Kallemeijn WW, Kuo CL, Artola M, Dai W, van Elk C, van Eijk M, van der Marel GA, Codée JDC, Florea BI, Aerts JMFG, Overkleeft HS, Davies GJ.

Nat Chem Biol. 2017 Aug;13(8):867-873. doi: 10.1038/nchembio.2395. Epub 2017 Jun 5.

19.

The influence of acceptor nucleophilicity on the glycosylation reaction mechanism.

van der Vorm S, Hansen T, Overkleeft HS, van der Marel GA, Codée JDC.

Chem Sci. 2017 Mar 1;8(3):1867-1875. doi: 10.1039/c6sc04638j. Epub 2016 Nov 9.

20.

Synthesis of the Staphylococcus aureus Strain M Capsular Polysaccharide Repeating Unit.

Hagen B, van Dijk JHM, Zhang Q, Overkleeft HS, van der Marel GA, Codée JDC.

Org Lett. 2017 May 19;19(10):2514-2517. doi: 10.1021/acs.orglett.7b00747. Epub 2017 May 9.

21.

Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors.

Beenakker TJM, Wander DPA, Offen WA, Artola M, Raich L, Ferraz MJ, Li KY, Houben JHPM, van Rijssel ER, Hansen T, van der Marel GA, Codée JDC, Aerts JMFG, Rovira C, Davies GJ, Overkleeft HS.

J Am Chem Soc. 2017 May 17;139(19):6534-6537. doi: 10.1021/jacs.7b01773. Epub 2017 May 5.

22.

Stereoselectivity of Conformationally Restricted Glucosazide Donors.

van der Vorm S, Overkleeft HS, van der Marel GA, Codée JDC.

J Org Chem. 2017 May 5;82(9):4793-4811. doi: 10.1021/acs.joc.7b00470. Epub 2017 Apr 25.

23.

Conformational Behaviour of Azasugars Based on Mannuronic Acid.

van Rijssel ER, Janssen APA, Males A, Davies GJ, van der Marel GA, Overkleeft HS, Codée JDC.

Chembiochem. 2017 Jul 4;18(13):1297-1304. doi: 10.1002/cbic.201700080. Epub 2017 Apr 18.

PMID:
28256791
24.

Simultaneous quantitation of sphingoid bases by UPLC-ESI-MS/MS with identical 13C-encoded internal standards.

Mirzaian M, Wisse P, Ferraz MJ, Marques ARA, Gaspar P, Oussoren SV, Kytidou K, Codée JDC, van der Marel G, Overkleeft HS, Aerts JM.

Clin Chim Acta. 2017 Mar;466:178-184. doi: 10.1016/j.cca.2017.01.014. Epub 2017 Jan 13.

PMID:
28089753
25.

Mapping the Reactivity and Selectivity of 2-Azidofucosyl Donors for the Assembly of N-Acetylfucosamine-Containing Bacterial Oligosaccharides.

Hagen B, Ali S, Overkleeft HS, van der Marel GA, Codée JD.

J Org Chem. 2017 Jan 20;82(2):848-868. doi: 10.1021/acs.joc.6b02593. Epub 2017 Jan 10.

26.

Teichoic acids: synthesis and applications.

van der Es D, Hogendorf WF, Overkleeft HS, van der Marel GA, Codée JD.

Chem Soc Rev. 2017 Mar 6;46(5):1464-1482. doi: 10.1039/c6cs00270f. Review.

PMID:
27990523
27.

Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes.

Jiang J, Kuo CL, Wu L, Franke C, Kallemeijn WW, Florea BI, van Meel E, van der Marel GA, Codée JD, Boot RG, Davies GJ, Overkleeft HS, Aerts JM.

ACS Cent Sci. 2016 May 25;2(5):351-8. doi: 10.1021/acscentsci.6b00057. Epub 2016 Apr 26. Erratum in: ACS Cent Sci. 2017 Jun 28;3(6):673.

28.

Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with (13)C-encoded natural S1P as internal standard.

Mirzaian M, Wisse P, Ferraz MJ, Marques ARA, Gabriel TL, van Roomen CPAA, Ottenhoff R, van Eijk M, Codée JDC, van der Marel GA, Overkleeft HS, Aerts JM.

Clin Chim Acta. 2016 Aug 1;459:36-44. doi: 10.1016/j.cca.2016.05.017. Epub 2016 May 21.

PMID:
27221202
29.

Synthesis of E. faecium wall teichoic acid fragments.

van der Es D, Groenia NA, Laverde D, Overkleeft HS, Huebner J, van der Marel GA, Codée JDC.

Bioorg Med Chem. 2016 Sep 1;24(17):3893-3907. doi: 10.1016/j.bmc.2016.03.019. Epub 2016 Mar 9.

PMID:
26993744
30.

Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors.

van den Berg RJ, van Rijssel ER, Ferraz MJ, Houben J, Strijland A, Donker-Koopman WE, Wennekes T, Bonger KM, Ghisaidoobe AB, Hoogendoorn S, van der Marel GA, Codée JD, Overkleeft HS, Aerts JM.

ChemMedChem. 2015 Dec;10(12):2042-62. doi: 10.1002/cmdc.201500407. Epub 2015 Oct 23.

PMID:
26492941
31.

Chemoselective Cleavage of p-Methoxybenzyl and 2-Naphthylmethyl Ethers Using a Catalytic Amount of HCl in Hexafluoro-2-propanol.

Volbeda AG, Kistemaker HA, Overkleeft HS, van der Marel GA, Filippov DV, Codée JD.

J Org Chem. 2015 Sep 4;80(17):8796-806. doi: 10.1021/acs.joc.5b01030. Epub 2015 Aug 14.

PMID:
26230920
32.

Comparing Cyclophellitol N-Alkyl and N-Acyl Cyclophellitol Aziridines as Activity-Based Glycosidase Probes.

Jiang J, Beenakker TJ, Kallemeijn WW, van der Marel GA, van den Elst H, Codée JD, Aerts JM, Overkleeft HS.

Chemistry. 2015 Jul 20;21(30):10861-9. doi: 10.1002/chem.201501313. Epub 2015 Jun 12.

PMID:
26073749
33.

Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy.

Wisse P, de Geus MA, Cross G, van den Nieuwendijk AM, van Rooden EJ, van den Berg RJ, Aerts JM, van der Marel GA, Codée JD, Overkleeft HS.

J Org Chem. 2015 Jul 17;80(14):7258-65. doi: 10.1021/acs.joc.5b00823. Epub 2015 Jun 25.

PMID:
26061009
34.

Lipophilic Muramyl Dipeptide-Antigen Conjugates as Immunostimulating Agents.

Willems MM, Zom GG, Meeuwenoord N, Khan S, Ossendorp F, Overkleeft HS, van der Marel GA, Filippov DV, Codée JD.

ChemMedChem. 2016 Jan 19;11(2):190-8. doi: 10.1002/cmdc.201500196. Epub 2015 Jun 9.

PMID:
26059481
35.

Acceptor reactivity in the total synthesis of alginate fragments containing α-L-guluronic acid and β-D-mannuronic acid.

Zhang Q, van Rijssel ER, Walvoort MT, Overkleeft HS, van der Marel GA, Codée JD.

Angew Chem Int Ed Engl. 2015 Jun 22;54(26):7670-3. doi: 10.1002/anie.201502581. Epub 2015 May 8.

PMID:
25960101
36.

In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 α-l-fucosidases.

Jiang J, Kallemeijn WW, Wright DW, van den Nieuwendijk AMCH, Rohde VC, Folch EC, van den Elst H, Florea BI, Scheij S, Donker-Koopman WE, Verhoek M, Li N, Schürmann M, Mink D, Boot RG, Codée JDC, van der Marel GA, Davies GJ, Aerts JMFG, Overkleeft HS.

Chem Sci. 2015 May 1;6(5):2782-false. doi: 10.1039/c4sc03739a. Epub 2015 Feb 9.

37.

Stereoselectivity in the Lewis acid mediated reduction of ketofuranoses.

van Rijssel ER, van Delft P, van Marle DV, Bijvoets SM, Lodder G, Overkleeft HS, van der Marel GA, Filippov DV, Codée JD.

J Org Chem. 2015 May 1;80(9):4553-65. doi: 10.1021/acs.joc.5b00419. Epub 2015 Apr 13.

PMID:
25826382
38.

A sensitive gel-based method combining distinct cyclophellitol-based probes for the identification of acid/base residues in human retaining β-glucosidases.

Kallemeijn WW, Witte MD, Voorn-Brouwer TM, Walvoort MT, Li KY, Codée JD, van der Marel GA, Boot RG, Overkleeft HS, Aerts JM.

J Biol Chem. 2014 Dec 19;289(51):35351-62. doi: 10.1074/jbc.M114.593376. Epub 2014 Oct 24.

39.

PhoR autokinase activity is controlled by an intermediate in wall teichoic acid metabolism that is sensed by the intracellular PAS domain during the PhoPR-mediated phosphate limitation response of Bacillus subtilis.

Botella E, Devine SK, Hubner S, Salzberg LI, Gale RT, Brown ED, Link H, Sauer U, Codée JD, Noone D, Devine KM.

Mol Microbiol. 2014 Dec;94(6):1242-59. doi: 10.1111/mmi.12833. Epub 2014 Nov 11.

40.

P. aeruginosa SGNH hydrolase-like proteins AlgJ and AlgX have similar topology but separate and distinct roles in alginate acetylation.

Baker P, Ricer T, Moynihan PJ, Kitova EN, Walvoort MT, Little DJ, Whitney JC, Dawson K, Weadge JT, Robinson H, Ohman DE, Codée JD, Klassen JS, Clarke AJ, Howell PL.

PLoS Pathog. 2014 Aug 28;10(8):e1004334. doi: 10.1371/journal.ppat.1004334. eCollection 2014 Aug.

41.

Exploring functional cyclophellitol analogues as human retaining beta-glucosidase inhibitors.

Li KY, Jiang J, Witte MD, Kallemeijn WW, Donker-Koopman WE, Boot RG, Aerts JM, Codée JD, van der Marel GA, Overkleeft HS.

Org Biomol Chem. 2014 Oct 21;12(39):7786-91. doi: 10.1039/c4ob01611d. Epub 2014 Aug 26.

PMID:
25156485
42.

Potent and selective activity-based probes for GH27 human retaining α-galactosidases.

Willems LI, Beenakker TJ, Murray B, Scheij S, Kallemeijn WW, Boot RG, Verhoek M, Donker-Koopman WE, Ferraz MJ, van Rijssel ER, Florea BI, Codée JD, van der Marel GA, Aerts JM, Overkleeft HS.

J Am Chem Soc. 2014 Aug 20;136(33):11622-5. doi: 10.1021/ja507040n. Epub 2014 Aug 11.

PMID:
25105979
43.

Design and synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates.

Duivenvoorden BA, Ghauharali K, Scheij S, Boot RG, Aerts JM, van der Marel GA, Overkleeft HS, Codée JD.

Carbohydr Res. 2014 Nov 18;399:26-37. doi: 10.1016/j.carres.2014.07.007. Epub 2014 Jul 18.

PMID:
25104395
44.

From covalent glycosidase inhibitors to activity-based glycosidase probes.

Willems LI, Jiang J, Li KY, Witte MD, Kallemeijn WW, Beenakker TJ, Schröder SP, Aerts JM, van der Marel GA, Codée JD, Overkleeft HS.

Chemistry. 2014 Aug 25;20(35):10864-72. doi: 10.1002/chem.201404014. Epub 2014 Aug 5.

PMID:
25100671
45.

Furanosyl oxocarbenium ion stability and stereoselectivity.

van Rijssel ER, van Delft P, Lodder G, Overkleeft HS, van der Marel GA, Filippov DV, Codée JD.

Angew Chem Int Ed Engl. 2014 Sep 22;53(39):10381-5. doi: 10.1002/anie.201405477. Epub 2014 Jul 31.

PMID:
25081839
46.

N-tetradecylcarbamyl lipopeptides as novel agonists for Toll-like receptor 2.

Willems MM, Zom GG, Khan S, Meeuwenoord N, Melief CJ, van der Stelt M, Overkleeft HS, Codée JD, van der Marel GA, Ossendorp F, Filippov DV.

J Med Chem. 2014 Aug 14;57(15):6873-8. doi: 10.1021/jm500722p. Epub 2014 Jul 23.

PMID:
25019313
47.

Design, automated synthesis and immunological evaluation of NOD2-ligand-antigen conjugates.

Willems MM, Zom GG, Meeuwenoord N, Ossendorp FA, Overkleeft HS, van der Marel GA, Codée JD, Filippov DV.

Beilstein J Org Chem. 2014 Jun 26;10:1445-53. doi: 10.3762/bjoc.10.148. eCollection 2014.

48.

Activation of glycosyl halides by halogen bonding.

Castelli R, Schindler S, Walter SM, Kniep F, Overkleeft HS, Van der Marel GA, Huber SM, Codée JD.

Chem Asian J. 2014 Aug;9(8):2095-8. doi: 10.1002/asia.201402259. Epub 2014 Jun 24.

PMID:
24962953
49.

Catalytic mechanism and mode of action of the periplasmic alginate epimerase AlgG.

Wolfram F, Kitova EN, Robinson H, Walvoort MT, Codée JD, Klassen JS, Howell PL.

J Biol Chem. 2014 Feb 28;289(9):6006-19. doi: 10.1074/jbc.M113.533158. Epub 2014 Jan 7.

50.

Chair interconversion and reactivity of mannuronic acid esters.

Rönnols J, Walvoort MT, van der Marel GA, Codée JD, Widmalm G.

Org Biomol Chem. 2013 Dec 14;11(46):8127-34. doi: 10.1039/c3ob41747f.

PMID:
24173496

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