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Items: 40

1.

The Energetic Significance of Metallophilic Interactions.

Zheng Q, Borsley S, Nichol GS, Duarte F, Cockroft SL.

Angew Chem Int Ed Engl. 2019 Sep 2;58(36):12617-12623. doi: 10.1002/anie.201904207. Epub 2019 Aug 2. Review.

PMID:
31268614
2.

Synthetically Diversified Protein Nanopores: Resolving Click Reaction Mechanisms.

Haugland MM, Borsley S, Cairns-Gibson DF, Elmi A, Cockroft SL.

ACS Nano. 2019 Apr 23;13(4):4101-4110. doi: 10.1021/acsnano.8b08691. Epub 2019 Mar 18.

PMID:
30864781
3.

Nanopore Detection of Single-Molecule Binding within a Metallosupramolecular Cage.

Borsley S, Cooper JA, Lusby PJ, Cockroft SL.

Chemistry. 2018 Mar 26;24(18):4542-4546. doi: 10.1002/chem.201800760. Epub 2018 Mar 9.

PMID:
29446552
4.

Simultaneous G-Quadruplex DNA Logic.

Bader A, Cockroft SL.

Chemistry. 2018 Apr 3;24(19):4820-4824. doi: 10.1002/chem.201800756. Epub 2018 Mar 7.

PMID:
29446498
5.

An RNA-dependent mechanism for transient expression of bacterial translocation filaments.

Wang D, McAteer SP, Wawszczyk AB, Russell CD, Tahoun A, Elmi A, Cockroft SL, Tollervey D, Granneman S, Tree JJ, Gally DL.

Nucleic Acids Res. 2018 Apr 20;46(7):3366-3381. doi: 10.1093/nar/gky096.

6.

In Situ Synthetic Functionalization of a Transmembrane Protein Nanopore.

Borsley S, Cockroft SL.

ACS Nano. 2018 Jan 23;12(1):786-794. doi: 10.1021/acsnano.7b08105. Epub 2017 Dec 19.

PMID:
29244946
7.

The Role of Terminal Functionality in the Membrane and Antibacterial Activity of Peptaibol-Mimetic Aib Foldamers.

Adam C, Peters AD, Lizio MG, Whitehead GFS, Diemer V, Cooper JA, Cockroft SL, Clayden J, Webb SJ.

Chemistry. 2018 Feb 9;24(9):2249-2256. doi: 10.1002/chem.201705299. Epub 2018 Jan 17.

PMID:
29210477
8.

The Origin of Chalcogen-Bonding Interactions.

Pascoe DJ, Ling KB, Cockroft SL.

J Am Chem Soc. 2017 Oct 25;139(42):15160-15167. doi: 10.1021/jacs.7b08511. Epub 2017 Oct 17.

PMID:
28985065
9.

Discrimination of supramolecular chirality using a protein nanopore.

Cooper JA, Borsley S, Lusby PJ, Cockroft SL.

Chem Sci. 2017 Jul 1;8(7):5005-5009. doi: 10.1039/c7sc01940h. Epub 2017 May 11.

10.

High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast.

Burlacu E, Lackmann F, Aguilar LC, Belikov S, Nues RV, Trahan C, Hector RD, Dominelli-Whiteley N, Cockroft SL, Wieslander L, Oeffinger M, Granneman S.

Nat Commun. 2017 Sep 28;8(1):714. doi: 10.1038/s41467-017-00761-8.

11.

Structural evidence for the covalent modification of FabH by 4,5-dichloro-1,2-dithiol-3-one (HR45).

Ekström AG, Kelly V, Marles-Wright J, Cockroft SL, Campopiano DJ.

Org Biomol Chem. 2017 Aug 2;15(30):6310-6313. doi: 10.1039/c7ob01396e.

12.

Defocused Imaging of UV-Driven Surface-Bound Molecular Motors.

Krajnik B, Chen J, Watson MA, Cockroft SL, Feringa BL, Hofkens J.

J Am Chem Soc. 2017 May 31;139(21):7156-7159. doi: 10.1021/jacs.7b02758. Epub 2017 May 18.

PMID:
28497688
13.

Strong Short-Range Cooperativity in Hydrogen-Bond Chains.

Dominelli-Whiteley N, Brown JJ, Muchowska KB, Mati IK, Adam C, Hubbard TA, Elmi A, Brown AJ, Bell IAW, Cockroft SL.

Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7658-7662. doi: 10.1002/anie.201703757. Epub 2017 Jun 1.

14.

Transmembrane Signalling: Membrane messengers.

Cockroft SL.

Nat Chem. 2017 Apr 21;9(5):406-407. doi: 10.1038/nchem.2775. No abstract available.

PMID:
28430206
15.

The Limit of Intramolecular H-Bonding.

Hubbard TA, Brown AJ, Bell IA, Cockroft SL.

J Am Chem Soc. 2016 Nov 23;138(46):15114-15117. Epub 2016 Nov 9.

PMID:
27933885
16.

Man-made molecular machines: membrane bound.

Watson MA, Cockroft SL.

Chem Soc Rev. 2016 Nov 7;45(22):6118-6129. Review.

PMID:
26932423
17.

Length-Dependent Formation of Transmembrane Pores by 310-Helical α-Aminoisobutyric Acid Foldamers.

Jones JE, Diemer V, Adam C, Raftery J, Ruscoe RE, Sengel JT, Wallace MI, Bader A, Cockroft SL, Clayden J, Webb SJ.

J Am Chem Soc. 2016 Jan 20;138(2):688-95. doi: 10.1021/jacs.5b12057. Epub 2016 Jan 8.

18.

An Autonomously Reciprocating Transmembrane Nanoactuator.

Watson MA, Cockroft SL.

Angew Chem Int Ed Engl. 2016 Jan 22;55(4):1345-9. doi: 10.1002/anie.201508845. Epub 2015 Dec 11.

PMID:
26661295
19.

Can Dispersion Forces Govern Aromatic Stacking in an Organic Solvent?

Yang L, Brazier JB, Hubbard TA, Rogers DM, Cockroft SL.

Angew Chem Int Ed Engl. 2016 Jan 18;55(3):912-6. doi: 10.1002/anie.201508056. Epub 2015 Dec 3.

PMID:
26632979
20.

Quantifying Solvophobic Effects in Nonpolar Cohesive Interactions.

Yang L, Adam C, Cockroft SL.

J Am Chem Soc. 2015 Aug 19;137(32):10084-7. doi: 10.1021/jacs.5b05736. Epub 2015 Aug 5.

PMID:
26159869
21.

DNA modulates solvent isotope effects in a nanopore.

Watson MA, Cockroft SL.

Chem Commun (Camb). 2015 Aug 7;51(61):12243-6. doi: 10.1039/c5cc01563d.

PMID:
26135014
22.

Partitioning solvophobic and dispersion forces in alkyl and perfluoroalkyl cohesion.

Adam C, Yang L, Cockroft SL.

Angew Chem Int Ed Engl. 2015 Jan 19;54(4):1164-7. doi: 10.1002/anie.201408982. Epub 2014 Nov 20.

PMID:
25413159
23.

Effect of solvent polarizability on the assembly and ordering of nanoscale polyhedral oligomeric silsesquioxane films.

Evmenenko G, Cockroft SL, Dutta P.

Langmuir. 2014 Jan 14;30(1):196-202. doi: 10.1021/la4041425. Epub 2013 Dec 30.

PMID:
24350622
24.

How much do van der Waals dispersion forces contribute to molecular recognition in solution?

Yang L, Adam C, Nichol GS, Cockroft SL.

Nat Chem. 2013 Dec;5(12):1006-10. doi: 10.1038/nchem.1779. Epub 2013 Oct 20.

PMID:
24256863
25.

Can non-polar hydrogen atoms accept hydrogen bonds?

Yang L, Hubbard TA, Cockroft SL.

Chem Commun (Camb). 2014 May 25;50(40):5212-4. doi: 10.1039/c3cc46048g. Epub 2013 Oct 22.

PMID:
24145311
26.

Electrostatic modulation of aromatic rings via explicit solvation of substituents.

Muchowska KB, Adam C, Mati IK, Cockroft SL.

J Am Chem Soc. 2013 Jul 10;135(27):9976-9. doi: 10.1021/ja402566w. Epub 2013 Jun 25.

PMID:
23795664
27.

Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures.

Naughton C, Avlonitis N, Corless S, Prendergast JG, Mati IK, Eijk PP, Cockroft SL, Bradley M, Ylstra B, Gilbert N.

Nat Struct Mol Biol. 2013 Mar;20(3):387-95. doi: 10.1038/nsmb.2509. Epub 2013 Feb 17.

28.

Palladium(II)-mediated assembly of biotinylated ion channels.

Wilson CP, Boglio C, Ma L, Cockroft SL, Webb SJ.

Chemistry. 2011 Mar 14;17(12):3465-73. doi: 10.1002/chem.201002031. Epub 2011 Feb 15.

PMID:
21328491
29.

Real-time monitoring of DNA polymerase function and stepwise single-nucleotide DNA strand translocation through a protein nanopore.

Chu J, González-López M, Cockroft SL, Amorin M, Ghadiri MR.

Angew Chem Int Ed Engl. 2010 Dec 27;49(52):10106-9. doi: 10.1002/anie.201005460. No abstract available.

30.

Molecular balances for quantifying non-covalent interactions.

Mati IK, Cockroft SL.

Chem Soc Rev. 2010 Nov;39(11):4195-205. doi: 10.1039/b822665m. Epub 2010 Sep 16.

31.

Biological nanopores for single-molecule biophysics.

Ma L, Cockroft SL.

Chembiochem. 2010 Jan 4;11(1):25-34. doi: 10.1002/cbic.200900526. Review. No abstract available.

PMID:
19938028
32.

Desolvation and substituent effects in edge-to-face aromatic interactions.

Cockroft SL, Hunter CA.

Chem Commun (Camb). 2009 Jul 14;(26):3961-3. doi: 10.1039/b902351h. Epub 2009 May 27.

33.

A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution.

Cockroft SL, Chu J, Amorin M, Ghadiri MR.

J Am Chem Soc. 2008 Jan 23;130(3):818-20. doi: 10.1021/ja077082c. Epub 2008 Jan 1.

34.

Modular multi-level circuits from immobilized DNA-based logic gates.

Frezza BM, Cockroft SL, Ghadiri MR.

J Am Chem Soc. 2007 Dec 5;129(48):14875-9. Epub 2007 Nov 10.

PMID:
17994734
35.

Substituent effects on aromatic stacking interactions.

Cockroft SL, Perkins J, Zonta C, Adams H, Spey SE, Low CM, Vinter JG, Lawson KR, Urch CJ, Hunter CA.

Org Biomol Chem. 2007 Apr 7;5(7):1062-80. Epub 2007 Mar 7.

PMID:
17377660
36.

Chemical double-mutant cycles: dissecting non-covalent interactions.

Cockroft SL, Hunter CA.

Chem Soc Rev. 2007 Feb;36(2):172-88. Epub 2006 Nov 27. Review.

PMID:
17264921
37.

Desolvation tips the balance: solvent effects on aromatic interactions.

Cockroft SL, Hunter CA.

Chem Commun (Camb). 2006 Sep 28;(36):3806-8. Epub 2006 Aug 22.

PMID:
16969464
38.

Electrostatic control of aromatic stacking interactions.

Cockroft SL, Hunter CA, Lawson KR, Perkins J, Urch CJ.

J Am Chem Soc. 2005 Jun 22;127(24):8594-5.

PMID:
15954755
39.

Experimental measurement of noncovalent interactions between halogens and aromatic rings.

Adams H, Cockroft SL, Guardigli C, Hunter CA, Lawson KR, Perkins J, Spey SE, Urch CJ, Ford R.

Chembiochem. 2004 May 3;5(5):657-65.

PMID:
15122638
40.

The influence of nonspecific microsomal binding on apparent intrinsic clearance, and its prediction from physicochemical properties.

Austin RP, Barton P, Cockroft SL, Wenlock MC, Riley RJ.

Drug Metab Dispos. 2002 Dec;30(12):1497-503.

PMID:
12433825

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