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Items: 22


VEGAS as a Platform for Facile Directed Evolution in Mammalian Cells.

English JG, Olsen RHJ, Lansu K, Patel M, White K, Cockrell AS, Singh D, Strachan RT, Wacker D, Roth BL.

Cell. 2019 Jul 4. pii: S0092-8674(19)30622-1. doi: 10.1016/j.cell.2019.05.051. [Epub ahead of print]


The Human Sodium Iodide Symporter as a Reporter Gene for Studying Middle East Respiratory Syndrome Coronavirus Pathogenesis.

Chefer S, Seidel J, Cockrell AS, Yount B, Solomon J, Hagen KR, Liu DX, Huzella LM, Kumar MR, Postnikova E, Bohannon JK, Lackemeyer MG, Cooper K, Endlich-Frazier A, Sharma H, Thomasson D, Bartos C, Sayre PJ, Sims A, Dyall J, Holbrook MR, Jahrling PB, Baric RS, Johnson RF.

mSphere. 2018 Dec 12;3(6). pii: e00540-18. doi: 10.1128/mSphere.00540-18.


Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice.

Cockrell AS, Leist SR, Douglas MG, Baric RS.

Mamm Genome. 2018 Aug;29(7-8):367-383. doi: 10.1007/s00335-018-9760-9. Epub 2018 Jul 24. Review.


A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques.

Cockrell AS, Johnson JC, Moore IN, Liu DX, Bock KW, Douglas MG, Graham RL, Solomon J, Torzewski L, Bartos C, Hart R, Baric RS, Johnson RF.

Sci Rep. 2018 Jul 16;8(1):10727. doi: 10.1038/s41598-018-28900-1.


Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease.

Douglas MG, Kocher JF, Scobey T, Baric RS, Cockrell AS.

Virology. 2018 Apr;517:98-107. doi: 10.1016/j.virol.2017.12.006. Epub 2017 Dec 23.


Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice.

Maurizio PL, Ferris MT, Keele GR, Miller DR, Shaw GD, Whitmore AC, West A, Morrison CR, Noll KE, Plante KS, Cockrell AS, Threadgill DW, Pardo-Manuel de Villena F, Baric RS, Heise MT, Valdar W.

G3 (Bethesda). 2018 Feb 2;8(2):427-445. doi: 10.1534/g3.117.300438.


Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis.

Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH 3rd, Leist SR, Yount BL Jr, Graham RL, McAnarney ET, Stratton KG, Cockrell AS, Debbink K, Sims AC, Waters KM, Baric RS.

mSphere. 2017 Nov 15;2(6). pii: e00346-17. doi: 10.1128/mSphere.00346-17. eCollection 2017 Nov-Dec.


MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis.

Menachery VD, Mitchell HD, Cockrell AS, Gralinski LE, Yount BL Jr, Graham RL, McAnarney ET, Douglas MG, Scobey T, Beall A, Dinnon K 3rd, Kocher JF, Hale AE, Stratton KG, Waters KM, Baric RS.

MBio. 2017 Aug 22;8(4). pii: e00665-17. doi: 10.1128/mBio.00665-17.


Efficient Reverse Genetic Systems for Rapid Genetic Manipulation of Emergent and Preemergent Infectious Coronaviruses.

Cockrell AS, Beall A, Yount B, Baric R.

Methods Mol Biol. 2017;1602:59-81. doi: 10.1007/978-1-4939-6964-7_5.


An effective DNA vaccine platform for Middle East respiratory syndrome coronavirus.

Cockrell AS, Baric RS.

Ann Transl Med. 2016 Dec;4(24):499. doi: 10.21037/atm.2016.11.40. No abstract available.


A mouse model for MERS coronavirus-induced acute respiratory distress syndrome.

Cockrell AS, Yount BL, Scobey T, Jensen K, Douglas M, Beall A, Tang XC, Marasco WA, Heise MT, Baric RS.

Nat Microbiol. 2016 Nov 28;2:16226. doi: 10.1038/nmicrobiol.2016.226.


Glycosylation of mouse DPP4 plays a role in inhibiting Middle East respiratory syndrome coronavirus infection.

Peck KM, Cockrell AS, Yount BL, Scobey T, Baric RS, Heise MT.

J Virol. 2015 Apr;89(8):4696-9. doi: 10.1128/JVI.03445-14. Epub 2015 Feb 4.


Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection.

Cockrell AS, Peck KM, Yount BL, Agnihothram SS, Scobey T, Curnes NR, Baric RS, Heise MT.

J Virol. 2014 May;88(9):5195-9. doi: 10.1128/JVI.03764-13. Epub 2014 Feb 26.


X-linked inhibitor of apoptosis protein-mediated attenuation of apoptosis, using a novel cardiac-enhanced adeno-associated viral vector.

Piacentino V 3rd, Milano CA, Bolanos M, Schroder J, Messina E, Cockrell AS, Jones E, Krol A, Bursac N, Mao L, Devi GR, Samulski RJ, Bowles DE.

Hum Gene Ther. 2012 Jun;23(6):635-46. doi: 10.1089/hum.2011.186. Epub 2012 Mar 13.


The HIV-1 Rev/RRE system is required for HIV-1 5' UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles.

Cockrell AS, van Praag H, Santistevan N, Ma H, Kafri T.

Retrovirology. 2011 Jun 24;8:51. doi: 10.1186/1742-4690-8-51.


Gene delivery by lentivirus vectors.

Cockrell AS, Kafri T.

Mol Biotechnol. 2007 Jul;36(3):184-204. Review.


A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors.

Cockrell AS, Ma H, Fu K, McCown TJ, Kafri T.

Mol Ther. 2006 Aug;14(2):276-84. Epub 2006 Mar 3.


Transactivator and structurally optimized inducible lentiviral vectors.

Haack K, Cockrell AS, Ma H, Israeli D, Ho SN, McCown TJ, Kafri T.

Mol Ther. 2004 Sep;10(3):585-96.


HIV-1 vectors: fulfillment of expectations, further advancements, and still a way to go.

Cockrell AS, Kafri T.

Curr HIV Res. 2003 Oct;1(4):419-39. Review.


Role of nitric oxide in the regulation of acute and chronic inflammation.

Laroux FS, Lefer DJ, Kawachi S, Scalia R, Cockrell AS, Gray L, Van der Heyde H, Hoffman JM, Grisham MB.

Antioxid Redox Signal. 2000 Fall;2(3):391-6. Review.


Leukocyte-endothelial cell interactions in nitric oxide synthase-deficient mice.

Lefer DJ, Jones SP, Girod WG, Baines A, Grisham MB, Cockrell AS, Huang PL, Scalia R.

Am J Physiol. 1999 Jun;276(6):H1943-50. doi: 10.1152/ajpheart.1999.276.6.H1943.


Herpes simplex virus 2 UL45 is a type II membrane protein.

Cockrell AS, Muggeridge MI.

J Virol. 1998 May;72(5):4430-3.

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