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Items: 1 to 50 of 167

1.

Pitpnc1a Regulates Zebrafish Sleep and Wake Behavior through Modulation of Insulin-like Growth Factor Signaling.

Ashlin TG, Blunsom NJ, Ghosh M, Cockcroft S, Rihel J.

Cell Rep. 2018 Aug 7;24(6):1389-1396. doi: 10.1016/j.celrep.2018.07.012.

2.

Phospholipid transport protein function at organelle contact sites.

Cockcroft S, Raghu P.

Curr Opin Cell Biol. 2018 Aug;53:52-60. doi: 10.1016/j.ceb.2018.04.011. Epub 2018 May 30. Review.

3.

Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1.

Blunsom NJ, Gomez-Espinosa E, Ashlin TG, Cockcroft S.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Mar;1863(3):284-298. doi: 10.1016/j.bbalip.2017.12.005. Epub 2017 Dec 16.

4.

Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis.

Zhao L, Thorsheim CL, Suzuki A, Stalker TJ, Min SH, Lian L, Fairn GD, Cockcroft S, Durham A, Krishnaswamy S, Abrams CS.

Nat Commun. 2017 Oct 31;8(1):1216. doi: 10.1038/s41467-017-01181-4.

5.
6.

Ligand and membrane-binding behavior of the phosphatidylinositol transfer proteins PITPα and PITPβ.

Baptist M, Panagabko C, Cockcroft S, Atkinson J.

Biochem Cell Biol. 2016 Dec;94(6):528-533. Epub 2016 Apr 18.

PMID:
27783542
7.

The Drosophila photoreceptor as a model system for studying signalling at membrane contact sites.

Yadav S, Cockcroft S, Raghu P.

Biochem Soc Trans. 2016 Apr 15;44(2):447-51. doi: 10.1042/BST20150256. Review.

PMID:
27068953
8.

RdgBα reciprocally transfers PA and PI at ER-PM contact sites to maintain PI(4,5)P2 homoeostasis during phospholipase C signalling in Drosophila photoreceptors.

Cockcroft S, Garner K, Yadav S, Gomez-Espinoza E, Raghu P.

Biochem Soc Trans. 2016 Feb;44(1):286-92. doi: 10.1042/BST20150228. Review.

PMID:
26862217
9.

RDGBα, a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction.

Yadav S, Garner K, Georgiev P, Li M, Gomez-Espinosa E, Panda A, Mathre S, Okkenhaug H, Cockcroft S, Raghu P.

J Cell Sci. 2015 Sep 1;128(17):3330-44. doi: 10.1242/jcs.173476. Epub 2015 Jul 22.

10.

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport.

Gatta AT, Wong LH, Sere YY, Calderón-Noreña DM, Cockcroft S, Menon AK, Levine TP.

Elife. 2015 May 22;4. doi: 10.7554/eLife.07253.

11.

Fluoxetine elevates allopregnanolone in female rat brain but inhibits a steroid microsomal dehydrogenase rather than activating an aldo-keto reductase.

Fry JP, Li KY, Devall AJ, Cockcroft S, Honour JW, Lovick TA.

Br J Pharmacol. 2014 Dec;171(24):5870-80. doi: 10.1111/bph.12891. Epub 2014 Nov 24.

12.

Phosphatidylinositol binding of Saccharomyces cerevisiae Pdr16p represents an essential feature of this lipid transfer protein to provide protection against azole antifungals.

Holič R, Simová Z, Ashlin T, Pevala V, Poloncová K, Tahotná D, Kutejová E, Cockcroft S, Griač P.

Biochim Biophys Acta. 2014 Oct;1842(10):1483-90. doi: 10.1016/j.bbalip.2014.07.014. Epub 2014 Jul 25.

13.

The Concise Guide to PHARMACOLOGY 2013/14: overview.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M.

Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444.

14.

Identification of a Plasmodium falciparum phospholipid transfer protein.

van Ooij C, Withers-Martinez C, Ringel A, Cockcroft S, Haldar K, Blackman MJ.

J Biol Chem. 2013 Nov 1;288(44):31971-83. doi: 10.1074/jbc.M113.474189. Epub 2013 Sep 16.

15.

Potential role for phosphatidylinositol transfer protein (PITP) family in lipid transfer during phospholipase C signalling.

Cockcroft S, Garner K.

Adv Biol Regul. 2013 Sep;53(3):280-91. doi: 10.1016/j.jbior.2013.07.007. Epub 2013 Jul 21. Review.

PMID:
23916246
16.

The diverse functions of phosphatidylinositol transfer proteins.

Cockcroft S.

Curr Top Microbiol Immunol. 2012;362:185-208. doi: 10.1007/978-94-007-5025-8_9. Review.

PMID:
23086419
17.
18.

Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid.

Garner K, Hunt AN, Koster G, Somerharju P, Groves E, Li M, Raghu P, Holic R, Cockcroft S.

J Biol Chem. 2012 Sep 14;287(38):32263-76. doi: 10.1074/jbc.M112.375840. Epub 2012 Jul 21.

19.

14-3-3 protein and ATRAP bind to the soluble class IIB phosphatidylinositol transfer protein RdgBβ at distinct sites.

Cockcroft S, Garner K.

Biochem Soc Trans. 2012 Apr;40(2):451-6. doi: 10.1042/BST20110770. Review.

PMID:
22435829
21.

Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?

Cockcroft S, Garner K.

Crit Rev Biochem Mol Biol. 2011 Apr;46(2):89-117. doi: 10.3109/10409238.2010.538664. Epub 2011 Jan 31. Review.

PMID:
21275878
22.

Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum.

Carvou N, Holic R, Li M, Futter C, Skippen A, Cockcroft S.

J Cell Sci. 2010 Apr 15;123(Pt 8):1262-73. doi: 10.1242/jcs.061986. Epub 2010 Mar 23.

23.

Reversible bleb formation in mast cells stimulated with antigen is Ca2+/calmodulin-dependent and bleb size is regulated by ARF6.

Yanase Y, Carvou N, Frohman MA, Cockcroft S.

Biochem J. 2009 Dec 14;425(1):179-93. doi: 10.1042/BJ20091122.

PMID:
19845506
24.

How does national culture affect citizens' rights of access to personal health information and informed consent?

Cockcroft S, Sandhu N, Norris A.

Health Informatics J. 2009 Sep;15(3):229-43. doi: 10.1177/1460458209337444.

PMID:
19713397
25.

Special issue on phospholipase D.

Cockcroft S, Frohman M.

Biochim Biophys Acta. 2009 Sep;1791(9):837-8. doi: 10.1016/j.bbalip.2009.08.003. No abstract available.

PMID:
19703663
26.

Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases.

Cockcroft S.

Biochim Biophys Acta. 2009 Sep;1791(9):905-12. doi: 10.1016/j.bbalip.2009.03.007. Epub 2009 Mar 17. Review.

PMID:
19298865
27.

Insulin uptake across the luminal membrane of the rat proximal tubule in vivo and in vitro.

Kolman P, Pica A, Carvou N, Boyde A, Cockcroft S, Loesch A, Pizzey A, Simeoni M, Capasso G, Unwin RJ.

Am J Physiol Renal Physiol. 2009 May;296(5):F1227-37. doi: 10.1152/ajprenal.90351.2008. Epub 2009 Mar 4.

28.

A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum.

Leber W, Skippen A, Fivelman QL, Bowyer PW, Cockcroft S, Baker DA.

Int J Parasitol. 2009 May;39(6):645-53. doi: 10.1016/j.ijpara.2008.11.015. Epub 2009 Jan 10.

PMID:
19171150
29.

Measurement of phosphatidylinositol and phosphatidylcholine binding and transfer activity of the lipid transport protein PITP.

Cockcroft S.

Methods Mol Biol. 2009;462:363-77. doi: 10.1007/978-1-60327-115-8_23.

PMID:
19160681
30.

Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells.

Shadan S, Holic R, Carvou N, Ee P, Li M, Murray-Rust J, Cockcroft S.

Traffic. 2008 Sep;9(10):1743-56. doi: 10.1111/j.1600-0854.2008.00794.x. Epub 2008 Jul 9.

31.

The Role of Phosphatidylinositol Transfer Proteins (PITPs) in Intracellular Signalling.

Wiedemann C, Cockcroft S.

Trends Endocrinol Metab. 1998 Oct 1;9(8):324-8.

PMID:
18406297
32.

Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons.

Cosker KE, Shadan S, van Diepen M, Morgan C, Li M, Allen-Baume V, Hobbs C, Doherty P, Cockcroft S, Eickholt BJ.

J Cell Sci. 2008 Mar 15;121(Pt 6):796-803. doi: 10.1242/jcs.019166. Epub 2008 Feb 19.

33.

Human ITPK1: a reversible inositol phosphate kinase/phosphatase that links receptor-dependent phospholipase C to Ca2+-activated chloride channels.

Saiardi A, Cockcroft S.

Sci Signal. 2008 Jan 29;1(4):pe5. doi: 10.1126/stke.14pe5. Review. Erratum in: Sci Signal. 2008;1(7):er1.

PMID:
18272466
34.

PA binding of phosphatidylinositol 4-phosphate 5-kinase.

Stace C, Manifava M, Delon C, Coadwell J, Cockcroft S, Ktistakis NT.

Adv Enzyme Regul. 2008;48:55-72. doi: 10.1016/j.advenzreg.2007.11.008. Epub 2007 Nov 26. Review. No abstract available.

PMID:
18167315
35.

Compartmentalized signalling in neurons.

Pedarzani P, Cockcroft S, Challiss RA.

J Physiol. 2007 Oct 15;584(2):371-2. doi: 10.1113/jphysiol.2007.144766. No abstract available.

36.

Biochemical and biological functions of class I phosphatidylinositol transfer proteins.

Cockcroft S, Carvou N.

Biochim Biophys Acta. 2007 Jun;1771(6):677-91. Epub 2007 Apr 4. Review.

PMID:
17490911
37.

Trafficking of phosphatidylinositol by phosphatidylinositol transfer proteins.

Cockcroft S.

Biochem Soc Symp. 2007;(74):259-71. Review.

PMID:
17233595
38.

Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases.

Hyvola N, Diao A, McKenzie E, Skippen A, Cockcroft S, Lowe M.

EMBO J. 2006 Aug 23;25(16):3750-61. Epub 2006 Aug 10.

39.

Reconstitution system based on cytosol-depleted cells to study the regulation of phospholipase D.

Fensome-Green A, Cockcroft S.

Methods Mol Biol. 2006;332:299-310.

PMID:
16878701
40.

Bromoenol lactone, an inhibitor of Group V1A calcium-independent phospholipase A2 inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx.

Fensome-Green A, Stannard N, Li M, Bolsover S, Cockcroft S.

Cell Calcium. 2007 Feb;41(2):145-53. Epub 2006 Jul 18.

PMID:
16854462
41.

Signalling through phospholipase C interferes with clathrin-mediated endocytosis.

Carvou N, Norden AG, Unwin RJ, Cockcroft S.

Cell Signal. 2007 Jan;19(1):42-51. Epub 2006 Jun 6.

PMID:
16843639
43.

Measurement of phospholipase C by monitoring inositol phosphates using [3H]inositol-labeling protocols in permeabilized cells.

Skippen A, Swigart P, Cockcroft S.

Methods Mol Biol. 2006;312:183-93. No abstract available.

PMID:
16422198
44.

The latest phospholipase C, PLCeta, is implicated in neuronal function.

Cockcroft S.

Trends Biochem Sci. 2006 Jan;31(1):4-7. Epub 2005 Nov 28. Review.

PMID:
16310357
45.

Measurement of phospholipase C by monitoring inositol phosphates using [³H]inositol-labeling protocols in permeabilized cells.

Skippen A, Swigart P, Cockcroft S.

Methods Mol Biol. 2005;312:183-93. doi: 10.1385/1-59259-949-4:183.

PMID:
21341099
46.

Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha.

Hunt AN, Skippen AJ, Koster G, Postle AD, Cockcroft S.

Biochim Biophys Acta. 2004 Nov 8;1686(1-2):50-60.

PMID:
15522822
47.

Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.

Morgan CP, Skippen A, Segui B, Ball A, Allen-Baume V, Larijani B, Murray-Rust J, McDonald N, Sapkota G, Morrice N, Cockcroft S.

J Biol Chem. 2004 Nov 5;279(45):47159-71. Epub 2004 Aug 18.

48.
50.

Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol.

Tilley SJ, Skippen A, Murray-Rust J, Swigart PM, Stewart A, Morgan CP, Cockcroft S, McDonald NQ.

Structure. 2004 Feb;12(2):317-26. Erratum in: Structure (Camb). 2004 May;12(5):907.

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