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Items: 1 to 50 of 137

1.

The association study of lipid metabolism gene polymorphisms with AMD identifies a protective role for APOE-E2 allele in the wet form in a Northern Spanish population.

Fernández-Vega B, García M, Olivares L, Álvarez L, González-Fernández A, Artime E, Fernández-Vega Cueto A, Cobo T, Coca-Prados M, Vega JA, González-Iglesias H.

Acta Ophthalmol. 2019 Oct 26. doi: 10.1111/aos.14280. [Epub ahead of print]

PMID:
31654486
2.

Identification of myocilin as a blood plasma protein and analysis of its role in leukocyte adhesion to endothelial cell monolayers.

Aroca-Aguilar JD, Fernández-Navarro A, Ontañón J, Coca-Prados M, Escribano J.

PLoS One. 2018 Dec 17;13(12):e0209364. doi: 10.1371/journal.pone.0209364. eCollection 2018.

3.

The Zinc-Metallothionein Redox System Reduces Oxidative Stress in Retinal Pigment Epithelial Cells.

Rodríguez-Menéndez S, García M, Fernández B, Álvarez L, Fernández-Vega-Cueto A, Coca-Prados M, Pereiro R, González-Iglesias H.

Nutrients. 2018 Dec 2;10(12). pii: E1874. doi: 10.3390/nu10121874.

4.

Quantitative study of zinc and metallothioneins in the human retina and RPE cells by mass spectrometry-based methodologies.

Rodríguez-Menéndez S, Fernández B, García M, Álvarez L, Luisa Fernández M, Sanz-Medel A, Coca-Prados M, Pereiro R, González-Iglesias H.

Talanta. 2018 Feb 1;178:222-230. doi: 10.1016/j.talanta.2017.09.024. Epub 2017 Sep 13.

PMID:
29136815
5.

Metallothionein polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration.

García M, Álvarez L, Fernández Á, González-Iglesias H, Escribano J, Fernández-Vega B, Villota E, Fernández-Vega Cueto L, Fernández-Vega Á, Coca-Prados M.

Ophthalmic Genet. 2017 Sep-Oct;38(5):451-458. doi: 10.1080/13816810.2017.1288825. Epub 2017 Mar 1.

PMID:
28635422
6.

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.

Aung T, Ozaki M, Lee MC, Schlötzer-Schrehardt U, Thorleifsson G, Mizoguchi T, Igo RP Jr, Haripriya A, Williams SE, Astakhov YS, Orr AC, Burdon KP, Nakano S, Mori K, Abu-Amero K, Hauser M, Li Z, Prakadeeswari G, Bailey JNC, Cherecheanu AP, Kang JH, Nelson S, Hayashi K, Manabe SI, Kazama S, Zarnowski T, Inoue K, Irkec M, Coca-Prados M, Sugiyama K, Järvelä I, Schlottmann P, Lerner SF, Lamari H, Nilgün Y, Bikbov M, Park KH, Cha SC, Yamashiro K, Zenteno JC, Jonas JB, Kumar RS, Perera SA, Chan ASY, Kobakhidze N, George R, Vijaya L, Do T, Edward DP, de Juan Marcos L, Pakravan M, Moghimi S, Ideta R, Bach-Holm D, Kappelgaard P, Wirostko B, Thomas S, Gaston D, Bedard K, Greer WL, Yang Z, Chen X, Huang L, Sang J, Jia H, Jia L, Qiao C, Zhang H, Liu X, Zhao B, Wang YX, Xu L, Leruez S, Reynier P, Chichua G, Tabagari S, Uebe S, Zenkel M, Berner D, Mossböck G, Weisschuh N, Hoja U, Welge-Luessen UC, Mardin C, Founti P, Chatzikyriakidou A, Pappas T, Anastasopoulos E, Lambropoulos A, Ghosh A, Shetty R, Porporato N, Saravanan V, Venkatesh R, Shivkumar C, Kalpana N, Sarangapani S, Kanavi MR, Beni AN, Yazdani S, Lashay A, Naderifar H, Khatibi N, Fea A, Lavia C, Dallorto L, Rolle T, Frezzotti P, Paoli D, Salvi E, Manunta P, Mori Y, Miyata K, Higashide T, Chihara E, Ishiko S, Yoshida A, Yanagi M, Kiuchi Y, Ohashi T, Sakurai T, Sugimoto T, Chuman H, Aihara M, Inatani M, Miyake M, Gotoh N, Matsuda F, Yoshimura N, Ikeda Y, Ueno M, Sotozono C, Jeoung JW, Sagong M, Park KH, Ahn J, Cruz-Aguilar M, Ezzouhairi SM, Rafei A, Chong YF, Ng XY, Goh SR, Chen Y, Yong VHK, Khan MI, Olawoye OO, Ashaye AO, Ugbede I, Onakoya A, Kizor-Akaraiwe N, Teekhasaenee C, Suwan Y, Supakontanasan W, Okeke S, Uche NJ, Asimadu I, Ayub H, Akhtar F, Kosior-Jarecka E, Lukasik U, Lischinsky I, Castro V, Grossmann RP, Sunaric Megevand G, Roy S, Dervan E, Silke E, Rao A, Sahay P, Fornero P, Cuello O, Sivori D, Zompa T, Mills RA, Souzeau E, Mitchell P, Wang JJ, Hewitt AW, Coote M, Crowston JG, Astakhov SY, Akopov EL, Emelyanov A, Vysochinskaya V, Kazakbaeva G, Fayzrakhmanov R, Al-Obeidan SA, Owaidhah O, Aljasim LA, Chowbay B, Foo JN, Soh RQ, Sim KS, Xie Z, Cheong AWO, Mok SQ, Soo HM, Chen XY, Peh SQ, Heng KK, Husain R, Ho SL, Hillmer AM, Cheng CY, Escudero-Domínguez FA, González-Sarmiento R, Martinon-Torres F, Salas A, Pathanapitoon K, Hansapinyo L, Wanichwecharugruang B, Kitnarong N, Sakuntabhai A, Nguyn HX, Nguyn GTT, Nguyn TV, Zenz W, Binder A, Klobassa DS, Hibberd ML, Davila S, Herms S, Nöthen MM, Moebus S, Rautenbach RM, Ziskind A, Carmichael TR, Ramsay M, Álvarez L, García M, González-Iglesias H, Rodríguez-Calvo PP, Fernández-Vega Cueto L, Oguz Ç, Tamcelik N, Atalay E, Batu B, Aktas D, Kasım B, Wilson MR, Coleman AL, Liu Y, Challa P, Herndon L, Kuchtey RW, Kuchtey J, Curtin K, Chaya CJ, Crandall A, Zangwill LM, Wong TY, Nakano M, Kinoshita S, den Hollander AI, Vesti E, Fingert JH, Lee RK, Sit AJ, Shingleton BJ, Wang N, Cusi D, Qamar R, Kraft P, Pericak-Vance MA, Raychaudhuri S, Heegaard S, Kivelä T, Reis A, Kruse FE, Weinreb RN, Pasquale LR, Haines JL, Thorsteinsdottir U, Jonasson F, Allingham RR, Milea D, Ritch R, Kubota T, Tashiro K, Vithana EN, Micheal S, Topouzis F, Craig JE, Dubina M, Sundaresan P, Stefansson K, Wiggs JL, Pasutto F, Khor CC.

Nat Genet. 2017 Jul;49(7):993-1004. doi: 10.1038/ng.3875. Epub 2017 May 29.

7.

Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development.

Ferre-Fernández JJ, Aroca-Aguilar JD, Medina-Trillo C, Bonet-Fernández JM, Méndez-Hernández CD, Morales-Fernández L, Corton M, Cabañero-Valera MJ, Gut M, Tonda R, Ayuso C, Coca-Prados M, García-Feijoo J, Escribano J.

Sci Rep. 2017 Apr 11;7:46175. doi: 10.1038/srep46175.

8.

LOXL1 gene variants and their association with pseudoexfoliation glaucoma (XFG) in Spanish patients.

Álvarez L, García M, González-Iglesias H, Escribano J, Rodríguez-Calvo PP, Fernández-Vega L, Coca-Prados M.

BMC Med Genet. 2015 Aug 31;16:72. doi: 10.1186/s12881-015-0221-y.

9.

CFH polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration.

García M, Álvarez L, Nogacka AM, González-Iglesias H, Escribano J, Fernández-Vega B, Fernández-Vega Á, Fernández-Vega L, Coca-Prados M.

Acta Ophthalmol. 2015 Dec;93(8):e658-66. doi: 10.1111/aos.12790. Epub 2015 Jul 8.

10.

Sensitive targeted multiple protein quantification based on elemental detection of quantum dots.

Montoro Bustos AR, Garcia-Cortes M, González-Iglesias H, Ruiz Encinar J, Costa-Fernández JM, Coca-Prados M, Sanz-Medel A.

Anal Chim Acta. 2015 Jun 16;879:77-84. doi: 10.1016/j.aca.2015.03.015. Epub 2015 Mar 10.

PMID:
26002480
11.

A renal-like organic anion transport system in the ciliary epithelium of the bovine and human eye.

Lee J, Shahidullah M, Hotchkiss A, Coca-Prados M, Delamere NA, Pelis RM.

Mol Pharmacol. 2015 Apr;87(4):697-705. doi: 10.1124/mol.114.096578. Epub 2015 Feb 6.

12.

Quantitative selenium speciation by HPLC-ICP-MS(IDA) and simultaneous activity measurements in human vitreous humor.

González de Vega R, Fernández-Sánchez ML, González Iglesias H, Coca Prados M, Sanz-Medel A.

Anal Bioanal Chem. 2015 Mar;407(9):2405-13. doi: 10.1007/s00216-014-8241-6. Epub 2014 Oct 26.

PMID:
25344931
13.

The blood-aqueous barrier in health and disease.

Coca-Prados M.

J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S36-8. doi: 10.1097/IJG.0000000000000107. Review.

PMID:
25275903
14.

Characterization of vitamin D production by human ocular barrier cells.

Alsalem JA, Patel D, Susarla R, Coca-Prados M, Bland R, Walker EA, Rauz S, Wallace GR.

Invest Ophthalmol Vis Sci. 2014 Apr 7;55(4):2140-7. doi: 10.1167/iovs.13-13019.

PMID:
24576880
15.

Quantitative bioimaging of trace elements in the human lens by LA-ICP-MS.

Konz I, Fernández B, Fernández ML, Pereiro R, González-Iglesias H, Coca-Prados M, Sanz-Medel A.

Anal Bioanal Chem. 2014 Apr;406(9-10):2343-8. doi: 10.1007/s00216-014-7617-y. Epub 2014 Feb 6.

PMID:
24500754
16.

Metallothioneins (MTs) in the human eye: a perspective article on the zinc-MT redox cycle.

Gonzalez-Iglesias H, Alvarez L, García M, Petrash C, Sanz-Medel A, Coca-Prados M.

Metallomics. 2014 Feb;6(2):201-8. doi: 10.1039/c3mt00298e. Review.

PMID:
24419560
17.

Comparative proteomic study in serum of patients with primary open-angle glaucoma and pseudoexfoliation glaucoma.

González-Iglesias H, Álvarez L, García M, Escribano J, Rodríguez-Calvo PP, Fernández-Vega L, Coca-Prados M.

J Proteomics. 2014 Feb 26;98:65-78. doi: 10.1016/j.jprot.2013.12.006. Epub 2013 Dec 16.

PMID:
24355480
18.

Gold internal standard correction for elemental imaging of soft tissue sections by LA-ICP-MS: element distribution in eye microstructures.

Konz I, Fernández B, Fernández ML, Pereiro R, González H, Alvarez L, Coca-Prados M, Sanz-Medel A.

Anal Bioanal Chem. 2013 Apr;405(10):3091-6. doi: 10.1007/s00216-013-6778-4. Epub 2013 Feb 5.

PMID:
23380953
19.

Bicarbonate-dependent secretion and proteolytic processing of recombinant myocilin.

Aroca-Aguilar JD, Martínez-Redondo F, Martín-Gil A, Pintor J, Coca-Prados M, Escribano J.

PLoS One. 2013;8(1):e54385. doi: 10.1371/journal.pone.0054385. Epub 2013 Jan 16.

20.

The stoichiometric transition from Zn6Cu1-metallothionein to Zn7-metallothionein underlies the up-regulation of metallothionein (MT) expression: quantitative analysis of MT-metal load in eye cells.

Alvarez L, Gonzalez-Iglesias H, Garcia M, Ghosh S, Sanz-Medel A, Coca-Prados M.

J Biol Chem. 2012 Aug 17;287(34):28456-69. doi: 10.1074/jbc.M112.365015. Epub 2012 Jun 21.

21.

WDR36 and P53 gene variants and susceptibility to primary open-angle glaucoma: analysis of gene-gene interactions.

Blanco-Marchite C, Sánchez-Sánchez F, López-Garrido MP, Iñigez-de-Onzoño M, López-Martínez F, López-Sánchez E, Alvarez L, Rodríguez-Calvo PP, Méndez-Hernández C, Fernández-Vega L, García-Sánchez J, Coca-Prados M, García-Feijoo J, Escribano J.

Invest Ophthalmol Vis Sci. 2011 Oct 31;52(11):8467-78. doi: 10.1167/iovs.11-7489.

22.

Interaction of recombinant myocilin with the matricellular protein SPARC: functional implications.

Aroca-Aguilar JD, Sánchez-Sánchez F, Ghosh S, Fernández-Navarro A, Coca-Prados M, Escribano J.

Invest Ophthalmol Vis Sci. 2011 Jan 5;52(1):179-89. doi: 10.1167/iovs.09-4866. Print 2011 Jan.

23.

Functional role of proteolytic processing of recombinant myocilin in self-aggregation.

Aroca-Aguilar JD, Martínez-Redondo F, Sánchez-Sánchez F, Coca-Prados M, Escribano J.

Invest Ophthalmol Vis Sci. 2010 Jan;51(1):72-8. doi: 10.1167/iovs.09-4118. Epub 2009 Aug 20.

24.

Localization of multidrug resistance-associated protein 2 in the nonpigmented ciliary epithelium of the eye.

Pelis RM, Shahidullah M, Ghosh S, Coca-Prados M, Wright SH, Delamere NA.

J Pharmacol Exp Ther. 2009 May;329(2):479-85. doi: 10.1124/jpet.108.149625. Epub 2009 Feb 6.

25.

Heterozygous expression of myocilin glaucoma mutants increases secretion of the mutant forms and reduces extracellular processed myocilin.

Aroca-Aguilar JD, Sánchez-Sánchez F, Martínez-Redondo F, Coca-Prados M, Escribano J.

Mol Vis. 2008;14:2097-108. Epub 2008 Nov 21.

26.

Expression and purification of functional recombinant human pigment epithelium-derived factor (PEDF) secreted by the yeast Pichia pastoris.

Sánchez-Sánchez F, Aroca-Aguilar JD, Segura I, Ramírez-Castillejo C, Riese HH, Coca-Prados M, Escribano J.

J Biotechnol. 2008 Mar 20;134(1-2):193-201. doi: 10.1016/j.jbiotec.2008.01.005. Epub 2008 Jan 17.

PMID:
18282627
27.

Molecular analysis of neurolysin expression in the rat and bovine ciliary body.

Bertazolli-Filho R, Coca-Prados M, Haddad A, Laicine EM.

Curr Eye Res. 2007 Sep;32(9):751-6.

PMID:
17882707
28.

Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease.

Sánchez-Sánchez F, Martínez-Redondo F, Aroca-Aguilar JD, Coca-Prados M, Escribano J.

J Biol Chem. 2007 Sep 21;282(38):27810-24. Epub 2007 Jul 24.

29.

Role of MYOC and OPTN sequence variations in Spanish patients with primary open-angle glaucoma.

Lopez-Martinez F, Lopez-Garrido MP, Sanchez-Sanchez F, Campos-Mollo E, Coca-Prados M, Escribano J.

Mol Vis. 2007 Jun 14;13:862-72.

30.

New perspectives in aqueous humor secretion and in glaucoma: the ciliary body as a multifunctional neuroendocrine gland.

Coca-Prados M, Escribano J.

Prog Retin Eye Res. 2007 May;26(3):239-62. Epub 2007 Jan 17. Review.

PMID:
17321191
31.

Heterozygous CYP1B1 gene mutations in Spanish patients with primary open-angle glaucoma.

López-Garrido MP, Sánchez-Sánchez F, López-Martínez F, Aroca-Aguilar JD, Blanco-Marchite C, Coca-Prados M, Escribano J.

Mol Vis. 2006 Jul 11;12:748-55.

32.

Somatostatin modulates PI3K-Akt, eNOS and NHE activity in the ciliary epithelium.

Ghosh S, Choritz L, Geibel J, Coca-Prados M.

Mol Cell Endocrinol. 2006 Jul 11;253(1-2):63-75. Epub 2006 Jun 9.

PMID:
16764985
33.

Interaction of myocilin with the C-terminal region of hevin.

Li Y, Aroca-Aguilar JD, Ghosh S, Sánchez-Sánchez F, Escribano J, Coca-Prados M.

Biochem Biophys Res Commun. 2006 Jan 20;339(3):797-804. Epub 2005 Nov 22.

PMID:
16316624
34.
35.

Retinoid processing proteins in the ocular ciliary epithelium.

Salvador-Silva M, Ghosh S, Bertazolli-Filho R, Boatright JH, Nickerson JM, Garwin GG, Saari JC, Coca-Prados M.

Mol Vis. 2005 May 18;11:356-65.

36.

Selective upregulation of the A3 adenosine receptor in eyes with pseudoexfoliation syndrome and glaucoma.

Schlötzer-Schrehardt U, Zenkel M, Decking U, Haubs D, Kruse FE, Jünemann A, Coca-Prados M, Naumann GO.

Invest Ophthalmol Vis Sci. 2005 Jun;46(6):2023-34.

PMID:
15914619
37.

Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227.

Aroca-Aguilar JD, Sánchez-Sánchez F, Ghosh S, Coca-Prados M, Escribano J.

J Biol Chem. 2005 Jun 3;280(22):21043-51. Epub 2005 Mar 28.

38.

FOXC1 transcriptional regulatory activity is impaired by PBX1 in a filamin A-mediated manner.

Berry FB, O'Neill MA, Coca-Prados M, Walter MA.

Mol Cell Biol. 2005 Feb;25(4):1415-24.

39.

Hyposmotic activation of ICl,swell in rabbit nonpigmented ciliary epithelial cells involves increased ClC-3 trafficking to the plasma membrane.

Vessey JP, Shi C, Jollimore CA, Stevens KT, Coca-Prados M, Barnes S, Kelly ME.

Biochem Cell Biol. 2004 Dec;82(6):708-18.

PMID:
15674438
40.

Functional and molecular characterization of a volume-activated chloride channel in rabbit corneal epithelial cells.

Al-Nakkash L, Iserovich P, Coca-Prados M, Yang H, Reinach PS.

J Membr Biol. 2004 Sep 1;201(1):41-9.

PMID:
15635811
41.

Identification of target genes regulated by FOXC1 using nickel agarose-based chromatin enrichment.

Tamimi Y, Lines M, Coca-Prados M, Walter MA.

Invest Ophthalmol Vis Sci. 2004 Nov;45(11):3904-13.

PMID:
15505035
42.

The bovine iris-ciliary epithelium expresses components of rod phototransduction.

Ghosh S, Salvador-Silva M, Coca-Prados M.

Neurosci Lett. 2004 Nov 3;370(1):7-12.

PMID:
15489008
43.

Inhibition of NHE-1 Na+/H+ exchanger by natriuretic peptides in ocular nonpigmented ciliary epithelium.

Fidzinski P, Salvador-Silva M, Choritz L, Geibel J, Coca-Prados M.

Am J Physiol Cell Physiol. 2004 Sep;287(3):C655-63. Epub 2004 May 12.

44.

Sex steroid hormone metabolism takes place in human ocular cells.

Coca-Prados M, Ghosh S, Wang Y, Escribano J, Herrala A, Vihko P.

J Steroid Biochem Mol Biol. 2003 Aug;86(2):207-16.

PMID:
14568574
45.

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 lowers intraocular pressure in patients with ocular hypertension.

Rauz S, Cheung CM, Wood PJ, Coca-Prados M, Walker EA, Murray PI, Stewart PM.

QJM. 2003 Jul;96(7):481-90.

PMID:
12881590
46.
47.

Production, purification, and functional analysis of recombinant human and mouse 17beta-hydroxysteroid dehydrogenase type 7.

Törn S, Nokelainen P, Kurkela R, Pulkka A, Menjivar M, Ghosh S, Coca-Prados M, Peltoketo H, Isomaa V, Vihko P.

Biochem Biophys Res Commun. 2003 May 23;305(1):37-45.

PMID:
12732193
48.

Expression of cell surface transmembrane carbonic anhydrase genes CA9 and CA12 in the human eye: overexpression of CA12 (CAXII) in glaucoma.

Liao SY, Ivanov S, Ivanova A, Ghosh S, Cote MA, Keefe K, Coca-Prados M, Stanbridge EJ, Lerman MI.

J Med Genet. 2003 Apr;40(4):257-61.

49.

Serum- and glucocorticoid-regulated kinase isoform-1 and epithelial sodium channel subunits in human ocular ciliary epithelium.

Rauz S, Walker EA, Hughes SV, Coca-Prados M, Hewison M, Murray PI, Stewart PM.

Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1643-51.

PMID:
12657604
50.

CRALBP transcriptional regulation in ciliary epithelial, retinal Müller and retinal pigment epithelial cells.

Kennedy BN, Li C, Ortego J, Coca-Prados M, Sarthy VP, Crabb JW.

Exp Eye Res. 2003 Feb;76(2):257-60.

PMID:
12565814

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