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Items: 36

1.

GlcNAc De-N-Acetylase from the Hyperthermophilic Archaeon Sulfolobus solfataricus.

Iacono R, Strazzulli A, Maurelli L, Curci N, Casillo A, Corsaro MM, Moracci M, Cobucci-Ponzano B.

Appl Environ Microbiol. 2019 Jan 9;85(2). pii: e01879-18. doi: 10.1128/AEM.01879-18. Print 2019 Jan 15.

PMID:
30446550
2.

Conversion of xylan by recyclable spores of Bacillus subtilis displaying thermophilic enzymes.

Mattossovich R, Iacono R, Cangiano G, Cobucci-Ponzano B, Isticato R, Moracci M, Ricca E.

Microb Cell Fact. 2017 Nov 28;16(1):218. doi: 10.1186/s12934-017-0833-3.

3.

N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer of α-Glucosidase Activity for the Treatment of Pompe Disease.

D'Alonzo D, De Fenza M, Porto C, Iacono R, Huebecker M, Cobucci-Ponzano B, Priestman DA, Platt F, Parenti G, Moracci M, Palumbo G, Guaragna A.

J Med Chem. 2017 Dec 14;60(23):9462-9469. doi: 10.1021/acs.jmedchem.7b00646. Epub 2017 Nov 22.

PMID:
29112434
4.

Structure of human lysosomal acid α-glucosidase-a guide for the treatment of Pompe disease.

Roig-Zamboni V, Cobucci-Ponzano B, Iacono R, Ferrara MC, Germany S, Bourne Y, Parenti G, Moracci M, Sulzenbacher G.

Nat Commun. 2017 Oct 24;8(1):1111. doi: 10.1038/s41467-017-01263-3.

5.

Human a-L-fucosidase-1 attenuates the invasive properties of thyroid cancer.

Vecchio G, Parascandolo A, Allocca C, Ugolini C, Basolo F, Moracci M, Strazzulli A, Cobucci-Ponzano B, Laukkanen MO, Castellone MD, Tsuchida N.

Oncotarget. 2017 Apr 18;8(16):27075-27092. doi: 10.18632/oncotarget.15635.

6.

Introducing transgalactosylation activity into a family 42 β-galactosidase.

Strazzulli A, Cobucci-Ponzano B, Carillo S, Bedini E, Corsaro MM, Pocsfalvi G, Withers SG, Rossi M, Moracci M.

Glycobiology. 2017 May 1;27(5):425-437. doi: 10.1093/glycob/cwx013.

PMID:
28158578
7.

High-level expression of thermostable cellulolytic enzymes in tobacco transplastomic plants and their use in hydrolysis of an industrially pretreated Arundo donax L. biomass.

Castiglia D, Sannino L, Marcolongo L, Ionata E, Tamburino R, De Stradis A, Cobucci-Ponzano B, Moracci M, La Cara F, Scotti N.

Biotechnol Biofuels. 2016 Jul 22;9:154. doi: 10.1186/s13068-016-0569-z. eCollection 2016.

8.

Novel thermophilic hemicellulases for the conversion of lignocellulose for second generation biorefineries.

Cobucci-Ponzano B, Strazzulli A, Iacono R, Masturzo G, Giglio R, Rossi M, Moracci M.

Enzyme Microb Technol. 2015 Oct;78:63-73. doi: 10.1016/j.enzmictec.2015.06.014. Epub 2015 Jun 25.

PMID:
26215346
9.

RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code.

Di Giulio M, Moracci M, Cobucci-Ponzano B.

J Theor Biol. 2014 Oct 21;359:1-5. doi: 10.1016/j.jtbi.2014.05.037. Epub 2014 Jun 6.

PMID:
24911781
10.

The identification and molecular characterization of the first archaeal bifunctional exo-β-glucosidase/N-acetyl-β-glucosaminidase demonstrate that family GH116 is made of three functionally distinct subfamilies.

Ferrara MC, Cobucci-Ponzano B, Carpentieri A, Henrissat B, Rossi M, Amoresano A, Moracci M.

Biochim Biophys Acta. 2014 Jan;1840(1):367-77. doi: 10.1016/j.bbagen.2013.09.022. Epub 2013 Sep 21.

PMID:
24060745
11.

Translational recoding in archaea.

Cobucci-Ponzano B, Rossi M, Moracci M.

Extremophiles. 2012 Nov;16(6):793-803. doi: 10.1007/s00792-012-0482-8. Epub 2012 Sep 27. Review.

PMID:
23015064
12.

Pharmacological enhancement of α-glucosidase by the allosteric chaperone N-acetylcysteine.

Porto C, Ferrara MC, Meli M, Acampora E, Avolio V, Rosa M, Cobucci-Ponzano B, Colombo G, Moracci M, Andria G, Parenti G.

Mol Ther. 2012 Dec;20(12):2201-11. doi: 10.1038/mt.2012.152. Epub 2012 Sep 18.

13.

Thermophilic glycosynthases for oligosaccharides synthesis.

Cobucci-Ponzano B, Perugino G, Strazzulli A, Rossi M, Moracci M.

Methods Enzymol. 2012;510:273-300. doi: 10.1016/B978-0-12-415931-0.00015-X.

PMID:
22608732
14.

Glycosynthases as tools for the production of glycan analogs of natural products.

Cobucci-Ponzano B, Moracci M.

Nat Prod Rep. 2012 Jun;29(6):697-709. doi: 10.1039/c2np20032e. Epub 2012 Apr 16. Review.

PMID:
22504390
15.

A novel alpha-D-galactosynthase from Thermotoga maritima converts beta-D-galactopyranosyl azide to alpha-galacto-oligosaccharides.

Cobucci-Ponzano B, Zorzetti C, Strazzulli A, Carillo S, Bedini E, Corsaro MM, Comfort DA, Kelly RM, Rossi M, Moracci M.

Glycobiology. 2011 Apr;21(4):448-56. doi: 10.1093/glycob/cwq177. Epub 2010 Nov 17.

PMID:
21084405
16.

Engineering the stability and the activity of a glycoside hydrolase.

Cobucci-Ponzano B, Perugino G, Rossi M, Moracci M.

Protein Eng Des Sel. 2011 Jan;24(1-2):21-6. doi: 10.1093/protein/gzq085. Epub 2010 Oct 27. Review.

PMID:
20980336
17.

The molecular characterization of a novel GH38 α-mannosidase from the crenarchaeon Sulfolobus solfataricus revealed its ability in de-mannosylating glycoproteins.

Cobucci-Ponzano B, Conte F, Strazzulli A, Capasso C, Fiume I, Pocsfalvi G, Rossi M, Moracci M.

Biochimie. 2010 Dec;92(12):1895-907. doi: 10.1016/j.biochi.2010.07.016. Epub 2010 Aug 7.

PMID:
20696204
18.

A new archaeal beta-glycosidase from Sulfolobus solfataricus: seeding a novel retaining beta-glycan-specific glycoside hydrolase family along with the human non-lysosomal glucosylceramidase GBA2.

Cobucci-Ponzano B, Aurilia V, Riccio G, Henrissat B, Coutinho PM, Strazzulli A, Padula A, Corsaro MM, Pieretti G, Pocsfalvi G, Fiume I, Cannio R, Rossi M, Moracci M.

J Biol Chem. 2010 Jul 2;285(27):20691-703. doi: 10.1074/jbc.M109.086470. Epub 2010 Apr 28.

19.

Functional characterization and high-throughput proteomic analysis of interrupted genes in the archaeon Sulfolobus solfataricus.

Cobucci-Ponzano B, Guzzini L, Benelli D, Londei P, Perrodou E, Lecompte O, Tran D, Sun J, Wei J, Mathur EJ, Rossi M, Moracci M.

J Proteome Res. 2010 May 7;9(5):2496-507. doi: 10.1021/pr901166q.

PMID:
20192274
20.

beta-Glycosyl azides as substrates for alpha-glycosynthases: preparation of efficient alpha-L-fucosynthases.

Cobucci-Ponzano B, Conte F, Bedini E, Corsaro MM, Parrilli M, Sulzenbacher G, Lipski A, Dal Piaz F, Lepore L, Rossi M, Moracci M.

Chem Biol. 2009 Oct 30;16(10):1097-108. doi: 10.1016/j.chembiol.2009.09.013.

21.

The alpha-L-fucosidase from Sulfolobus solfataricus.

Cobucci-Ponzano B, Conte F, Rossi M, Moracci M.

Extremophiles. 2008 Jan;12(1):61-8. Epub 2007 Aug 9. Review.

PMID:
17687508
22.

A comparative infrared spectroscopic study of glycoside hydrolases from extremophilic archaea revealed different molecular mechanisms of adaptation to high temperatures.

Ausili A, Cobucci-Ponzano B, Di Lauro B, D'Avino R, Perugino G, Bertoli E, Scirè A, Rossi M, Tanfani F, Moracci M.

Proteins. 2007 Jun 1;67(4):991-1001.

PMID:
17357157
23.

Interrupted genes in extremophilic archaea: mechanisms of gene expression in early organisms.

Cobucci-Ponzano B, Rossi M, Moracci M.

Orig Life Evol Biosph. 2006 Dec;36(5-6):487-92. Review.

PMID:
17120127
24.

The gene of an archaeal alpha-L-fucosidase is expressed by translational frameshifting.

Cobucci-Ponzano B, Conte F, Benelli D, Londei P, Flagiello A, Monti M, Pucci P, Rossi M, Moracci M.

Nucleic Acids Res. 2006;34(15):4258-68. Epub 2006 Aug 18.

25.

Structural basis of the destabilization produced by an amino-terminal tag in the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus.

Ausili A, Cobucci-Ponzano B, Di Lauro B, D'Avino R, Scirè A, Rossi M, Tanfani F, Moracci M.

Biochimie. 2006 Jul;88(7):807-17. Epub 2006 Feb 9.

PMID:
16494988
26.

Probing the catalytically essential residues of the alpha-L-fucosidase from the hyperthermophilic archaeon Sulfolobus solfataricus.

Cobucci-Ponzano B, Mazzone M, Rossi M, Moracci M.

Biochemistry. 2005 Apr 26;44(16):6331-42.

PMID:
15835922
27.

Recoding in archaea.

Cobucci-Ponzano B, Rossi M, Moracci M.

Mol Microbiol. 2005 Jan;55(2):339-48. Review.

29.

Structural characterization of the nonameric assembly of an Archaeal alpha-L-fucosidase by synchrotron small angle X-ray scattering.

Rosano C, Zuccotti S, Cobucci-Ponzano B, Mazzone M, Rossi M, Moracci M, Petoukhov MV, Svergun DI, Bolognesi M.

Biochem Biophys Res Commun. 2004 Jul 16;320(1):176-82.

PMID:
15207718
30.

Identification of the catalytic nucleophile of the family 29 alpha-L-fucosidase from Sulfolobus solfataricus via chemical rescue of an inactive mutant.

Cobucci-Ponzano B, Trincone A, Giordano A, Rossi M, Moracci M.

Biochemistry. 2003 Aug 19;42(32):9525-31.

PMID:
12911294
31.

Identification of an archaeal alpha-L-fucosidase encoded by an interrupted gene. Production of a functional enzyme by mutations mimicking programmed -1 frameshifting.

Cobucci-Ponzano B, Trincone A, Giordano A, Rossi M, Moracci M.

J Biol Chem. 2003 Apr 25;278(17):14622-31. Epub 2003 Feb 4.

32.
33.

Enzymatic synthesis and hydrolysis of xylogluco-oligosaccharides using the first archaeal alpha-xylosidase from Sulfolobus solfataricus.

Trincone A, Cobucci-Ponzano B, Di Lauro B, Rossi M, Mitsuishi Y, Moracci M.

Extremophiles. 2001 Aug;5(4):277-82.

PMID:
11523897
34.

Enzymatic synthesis of oligosaccharides by two glycosyl hydrolases of Sulfolobus solfataricus.

Moracci M, Trincone A, Cobucci-Ponzano B, Perugino G, Ciaramella M, Rossi M.

Extremophiles. 2001 Jun;5(3):145-52. Review.

PMID:
11453457
35.

Activity and stability of hyperthermophilic enzymes: a comparative study on two archaeal beta-glycosidases.

Pouwels J, Moracci M, Cobucci-Ponzano B, Perugino G, van der Oost J, Kaper T, Lebbink JH, de Vos WM, Ciaramella M, Rossi M.

Extremophiles. 2000 Jun;4(3):157-64.

PMID:
10879560
36.

Identification and molecular characterization of the first alpha -xylosidase from an archaeon.

Moracci M, Cobucci Ponzano B, Trincone A, Fusco S, De Rosa M, van Der Oost J, Sensen CW, Charlebois RL, Rossi M.

J Biol Chem. 2000 Jul 21;275(29):22082-9.

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