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Items: 1 to 50 of 69

1.

Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis.

Krenzlin H, Behera P, Lorenz V, Passaro C, Zdioruk M, Nowicki MO, Grauwet K, Zhang H, Skubal M, Ito H, Zane R, Gutknecht M, Griessl MB, Ricklefs F, Ding L, Peled S, Rooj A, James CD, Cobbs CS, Cook CH, Chiocca EA, Lawler SE.

J Clin Invest. 2019 Mar 11;130:1671-1683. doi: 10.1172/JCI123375. eCollection 2019 Mar 11.

2.
3.

Epigenetic profiling for the molecular classification of metastatic brain tumors.

Orozco JIJ, Knijnenburg TA, Manughian-Peter AO, Salomon MP, Barkhoudarian G, Jalas JR, Wilmott JS, Hothi P, Wang X, Takasumi Y, Buckland ME, Thompson JF, Long GV, Cobbs CS, Shmulevich I, Kelly DF, Scolyer RA, Hoon DSB, Marzese DM.

Nat Commun. 2018 Nov 6;9(1):4627. doi: 10.1038/s41467-018-06715-y.

4.

Brain metastasis DNA methylomes, a novel resource for the identification of biological and clinical features.

Salomon MP, Orozco JIJ, Wilmott JS, Hothi P, Manughian-Peter AO, Cobbs CS, Scolyer RA, Hoon DSB, Marzese DM.

Sci Data. 2018 Nov 6;5:180245. doi: 10.1038/sdata.2018.245.

5.

Fatal Balamuthia mandrillaris brain infection associated with improper nasal lavage.

Piper KJ, Foster H, Susanto D, Maree CL, Thornton SD, Cobbs CS.

Int J Infect Dis. 2018 Dec;77:18-22. doi: 10.1016/j.ijid.2018.09.013. Epub 2018 Sep 20.

6.

Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

Liau LM, Ashkan K, Tran DD, Campian JL, Trusheim JE, Cobbs CS, Heth JA, Salacz M, Taylor S, D'Andre SD, Iwamoto FM, Dropcho EJ, Moshel YA, Walter KA, Pillainayagam CP, Aiken R, Chaudhary R, Goldlust SA, Bota DA, Duic P, Grewal J, Elinzano H, Toms SA, Lillehei KO, Mikkelsen T, Walbert T, Abram SR, Brenner AJ, Brem S, Ewend MG, Khagi S, Portnow J, Kim LJ, Loudon WG, Thompson RC, Avigan DE, Fink KL, Geoffroy FJ, Lindhorst S, Lutzky J, Sloan AE, Schackert G, Krex D, Meisel HJ, Wu J, Davis RP, Duma C, Etame AB, Mathieu D, Kesari S, Piccioni D, Westphal M, Baskin DS, New PZ, Lacroix M, May SA, Pluard TJ, Tse V, Green RM, Villano JL, Pearlman M, Petrecca K, Schulder M, Taylor LP, Maida AE, Prins RM, Cloughesy TF, Mulholland P, Bosch ML.

J Transl Med. 2018 Jun 29;16(1):179. doi: 10.1186/s12967-018-1552-1.

7.

First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.

Liau LM, Ashkan K, Tran DD, Campian JL, Trusheim JE, Cobbs CS, Heth JA, Salacz M, Taylor S, D'Andre SD, Iwamoto FM, Dropcho EJ, Moshel YA, Walter KA, Pillainayagam CP, Aiken R, Chaudhary R, Goldlust SA, Bota DA, Duic P, Grewal J, Elinzano H, Toms SA, Lillehei KO, Mikkelsen T, Walbert T, Abram SR, Brenner AJ, Brem S, Ewend MG, Khagi S, Portnow J, Kim LJ, Loudon WG, Thompson RC, Avigan DE, Fink KL, Geoffroy FJ, Lindhorst S, Lutzky J, Sloan AE, Schackert G, Krex D, Meisel HJ, Wu J, Davis RP, Duma C, Etame AB, Mathieu D, Kesari S, Piccioni D, Westphal M, Baskin DS, New PZ, Lacroix M, May SA, Pluard TJ, Tse V, Green RM, Villano JL, Pearlman M, Petrecca K, Schulder M, Taylor LP, Maida AE, Prins RM, Cloughesy TF, Mulholland P, Bosch ML.

J Transl Med. 2018 May 29;16(1):142. doi: 10.1186/s12967-018-1507-6. Erratum in: J Transl Med. 2018 Jun 29;16(1):179.

8.

Preoperative relative cerebral blood volume analysis in gliomas predicts survival and mitigates risk of biopsy sampling error.

McCullough BJ, Ader V, Aguedan B, Feng X, Susanto D, Benkers TL, Henson JW, Mayberg M, Cobbs CS, Gwinn RP, Monteith SJ, Newell DW, Delashaw J Jr, Fouke SJ, Rostad S, Keogh BP.

J Neurooncol. 2018 Jan;136(1):181-188. doi: 10.1007/s11060-017-2642-2. Epub 2017 Nov 2.

PMID:
29098571
9.

Human cytomegalovirus-mediated immunomodulation: Effects on glioblastoma progression.

Foster H, Ulasov IV, Cobbs CS.

Biochim Biophys Acta Rev Cancer. 2017 Aug;1868(1):273-276. doi: 10.1016/j.bbcan.2017.05.006. Epub 2017 May 26. Review.

PMID:
28554666
10.

A Cell-Surface Membrane Protein Signature for Glioblastoma.

Ghosh D, Funk CC, Caballero J, Shah N, Rouleau K, Earls JC, Soroceanu L, Foltz G, Cobbs CS, Price ND, Hood L.

Cell Syst. 2017 May 24;4(5):516-529.e7. doi: 10.1016/j.cels.2017.03.004. Epub 2017 Mar 29.

11.

Cytomegalovirus as an oncomodulatory agent in the progression of glioma.

Joseph GP, McDermott R, Baryshnikova MA, Cobbs CS, Ulasov IV.

Cancer Lett. 2017 Jan 1;384:79-85. doi: 10.1016/j.canlet.2016.10.022. Epub 2016 Oct 21. Review.

PMID:
27777041
12.

CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy.

Ulasov IV, Kaverina NV, Ghosh D, Baryshnikova MA, Kadagidze ZG, Karseladze AI, Baryshnikov AY, Cobbs CS.

Oncotarget. 2017 Apr 18;8(16):25989-25999. doi: 10.18632/oncotarget.11175.

13.

TGFβ-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme.

Ghosh D, Ulasov IV, Chen L, Harkins LE, Wallenborg K, Hothi P, Rostad S, Hood L, Cobbs CS.

Stem Cells. 2016 Sep;34(9):2276-89. doi: 10.1002/stem.2411. Epub 2016 Jul 4.

14.

Cytomegalovirus Immediate-Early Proteins Promote Stemness Properties in Glioblastoma.

Soroceanu L, Matlaf L, Khan S, Akhavan A, Singer E, Bezrookove V, Decker S, Ghanny S, Hadaczek P, Bengtsson H, Ohlfest J, Luciani-Torres MG, Harkins L, Perry A, Guo H, Soteropoulos P, Cobbs CS.

Cancer Res. 2015 Aug 1;75(15):3065-76. doi: 10.1158/0008-5472.CAN-14-3307.

15.

Tamoxifen improves cytopathic effect of oncolytic adenovirus in primary glioblastoma cells mediated through autophagy.

Ulasov IV, Shah N, Kaverina NV, Lee H, Lin B, Lieber A, Kadagidze ZG, Yoon JG, Schroeder B, Hothi P, Ghosh D, Baryshnikov AY, Cobbs CS.

Oncotarget. 2015 Feb 28;6(6):3977-87.

16.

Methods for the detection of cytomegalovirus in glioblastoma cells and tissues.

Cobbs CS, Matlaf L, Harkins LE.

Methods Mol Biol. 2014;1119:165-96. doi: 10.1007/978-1-62703-788-4_11.

PMID:
24639224
17.

Does valganciclovir have a role in glioblastoma therapy?

Cobbs CS.

Neuro Oncol. 2014 Mar;16(3):330-1. doi: 10.1093/neuonc/nou009. No abstract available.

18.

Cidofovir: a novel antitumor agent for glioblastoma.

Hadaczek P, Ozawa T, Soroceanu L, Yoshida Y, Matlaf L, Singer E, Fiallos E, James CD, Cobbs CS.

Clin Cancer Res. 2013 Dec 1;19(23):6473-83. doi: 10.1158/1078-0432.CCR-13-1121. Epub 2013 Oct 29.

19.

Cytomegalovirus and brain tumor: epidemiology, biology and therapeutic aspects.

Cobbs CS.

Curr Opin Oncol. 2013 Nov;25(6):682-8. doi: 10.1097/CCO.0000000000000005. Review.

PMID:
24097102
20.

Cytomegalovirus pp71 protein is expressed in human glioblastoma and promotes pro-angiogenic signaling by activation of stem cell factor.

Matlaf LA, Harkins LE, Bezrookove V, Cobbs CS, Soroceanu L.

PLoS One. 2013 Jul 5;8(7):e68176. doi: 10.1371/journal.pone.0068176. Print 2013.

21.

Consensus on the role of human cytomegalovirus in glioblastoma.

Dziurzynski K, Chang SM, Heimberger AB, Kalejta RF, McGregor Dallas SR, Smit M, Soroceanu L, Cobbs CS; HCMV and Gliomas Symposium.

Neuro Oncol. 2012 Mar;14(3):246-55. doi: 10.1093/neuonc/nor227. Epub 2012 Feb 8.

22.

Evolving evidence implicates cytomegalovirus as a promoter of malignant glioma pathogenesis.

Cobbs CS.

Herpesviridae. 2011 Oct 26;2(1):10. doi: 10.1186/2042-4280-2-10.

23.

Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype.

Soroceanu L, Matlaf L, Bezrookove V, Harkins L, Martinez R, Greene M, Soteropoulos P, Cobbs CS.

Cancer Res. 2011 Nov 1;71(21):6643-53. doi: 10.1158/0008-5472.CAN-11-0744. Epub 2011 Sep 7.

24.

Is HCMV a tumor promoter?

Soroceanu L, Cobbs CS.

Virus Res. 2011 May;157(2):193-203. doi: 10.1016/j.virusres.2010.10.026. Epub 2010 Oct 29. Review.

25.

Fibrous dysplasia.

Char DH, Barakos JA, Cobbs CS, Shiel MJ.

Orbit. 2010 Aug;29(4):216-8. doi: 10.3109/01676831003713991.

PMID:
20812841
26.

Detection of human cytomegalovirus in normal and neoplastic breast epithelium.

Harkins LE, Matlaf LA, Soroceanu L, Klemm K, Britt WJ, Wang W, Bland KI, Cobbs CS.

Herpesviridae. 2010 Dec 23;1(1):8. doi: 10.1186/2042-4280-1-8.

27.

The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.

Gaspar LE, Mehta MP, Patchell RA, Burri SH, Robinson PD, Morris RE, Ammirati M, Andrews DW, Asher AL, Cobbs CS, Kondziolka D, Linskey ME, Loeffler JS, McDermott M, Mikkelsen T, Olson JJ, Paleologos NA, Ryken TC, Kalkanis SN.

J Neurooncol. 2010 Jan;96(1):17-32. doi: 10.1007/s11060-009-0060-9. Epub 2009 Dec 4. Review.

28.

The role of surgical resection in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.

Kalkanis SN, Kondziolka D, Gaspar LE, Burri SH, Asher AL, Cobbs CS, Ammirati M, Robinson PD, Andrews DW, Loeffler JS, McDermott M, Mehta MP, Mikkelsen T, Olson JJ, Paleologos NA, Patchell RA, Ryken TC, Linskey ME.

J Neurooncol. 2010 Jan;96(1):33-43. doi: 10.1007/s11060-009-0061-8. Epub 2009 Dec 4. Review.

29.

The role of chemotherapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.

Mehta MP, Paleologos NA, Mikkelsen T, Robinson PD, Ammirati M, Andrews DW, Asher AL, Burri SH, Cobbs CS, Gaspar LE, Kondziolka D, Linskey ME, Loeffler JS, McDermott M, Olson JJ, Patchell RA, Ryken TC, Kalkanis SN.

J Neurooncol. 2010 Jan;96(1):71-83. doi: 10.1007/s11060-009-0062-7. Epub 2009 Dec 4. Review.

30.

The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.

Linskey ME, Andrews DW, Asher AL, Burri SH, Kondziolka D, Robinson PD, Ammirati M, Cobbs CS, Gaspar LE, Loeffler JS, McDermott M, Mehta MP, Mikkelsen T, Olson JJ, Paleologos NA, Patchell RA, Ryken TC, Kalkanis SN.

J Neurooncol. 2010 Jan;96(1):45-68. doi: 10.1007/s11060-009-0073-4. Epub 2009 Dec 4. Review. Erratum in: J Neurooncol. 2010 Jan;96(1):69-70.

31.

The role of retreatment in the management of recurrent/progressive brain metastases: a systematic review and evidence-based clinical practice guideline.

Ammirati M, Cobbs CS, Linskey ME, Paleologos NA, Ryken TC, Burri SH, Asher AL, Loeffler JS, Robinson PD, Andrews DW, Gaspar LE, Kondziolka D, McDermott M, Mehta MP, Mikkelsen T, Olson JJ, Patchell RA, Kalkanis SN.

J Neurooncol. 2010 Jan;96(1):85-96. doi: 10.1007/s11060-009-0055-6. Epub 2009 Dec 3. Review.

32.

The role of prophylactic anticonvulsants in the management of brain metastases: a systematic review and evidence-based clinical practice guideline.

Mikkelsen T, Paleologos NA, Robinson PD, Ammirati M, Andrews DW, Asher AL, Burri SH, Cobbs CS, Gaspar LE, Kondziolka D, Linskey ME, Loeffler JS, McDermott M, Mehta MP, Olson JJ, Patchell RA, Ryken TC, Kalkanis SN.

J Neurooncol. 2010 Jan;96(1):97-102. doi: 10.1007/s11060-009-0056-5. Epub 2009 Dec 3. Review.

33.

The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline.

Ryken TC, McDermott M, Robinson PD, Ammirati M, Andrews DW, Asher AL, Burri SH, Cobbs CS, Gaspar LE, Kondziolka D, Linskey ME, Loeffler JS, Mehta MP, Mikkelsen T, Olson JJ, Paleologos NA, Patchell RA, Kalkanis SN.

J Neurooncol. 2010 Jan;96(1):103-14. doi: 10.1007/s11060-009-0057-4. Epub 2009 Dec 3. Review.

34.

The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics.

Olson JJ, Paleologos NA, Gaspar LE, Robinson PD, Morris RE, Ammirati M, Andrews DW, Asher AL, Burri SH, Cobbs CS, Kondziolka D, Linskey ME, Loeffler JS, McDermott M, Mehta MP, Mikkelsen T, Patchell RA, Ryken TC, Kalkanis SN.

J Neurooncol. 2010 Jan;96(1):115-42. doi: 10.1007/s11060-009-0058-3. Epub 2009 Dec 3.

35.

Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection.

Soroceanu L, Akhavan A, Cobbs CS.

Nature. 2008 Sep 18;455(7211):391-5. doi: 10.1038/nature07209. Epub 2008 Aug 13.

PMID:
18701889
36.

Modulation of oncogenic phenotype in human glioma cells by cytomegalovirus IE1-mediated mitogenicity.

Cobbs CS, Soroceanu L, Denham S, Zhang W, Kraus MH.

Cancer Res. 2008 Feb 1;68(3):724-30. doi: 10.1158/0008-5472.CAN-07-2291.

37.

Human cytomegalovirus induces cellular tyrosine kinase signaling and promotes glioma cell invasiveness.

Cobbs CS, Soroceanu L, Denham S, Zhang W, Britt WJ, Pieper R, Kraus MH.

J Neurooncol. 2007 Dec;85(3):271-80. Epub 2007 Jun 23.

PMID:
17589804
38.

RE: "Lack of association of herpesviruses with brain tumors".

Scheurer ME, El-Zein R, Bondy ML, Harkins L, Cobbs CS.

J Neurovirol. 2007;13(1):85; author reply 86-7. No abstract available.

PMID:
17454453
39.

Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiforme.

Tang J, Shao W, Dorak MT, Li Y, Miike R, Lobashevsky E, Wiencke JK, Wrensch M, Kaslow RA, Cobbs CS.

Cancer Epidemiol Biomarkers Prev. 2005 Aug;14(8):2040-4.

40.

Molecular typing of human leukocyte antigen and related polymorphisms following whole genome amplification.

Shao W, Tang J, Dorak MT, Song W, Lobashevsky E, Cobbs CS, Wrensch MR, Kaslow RA.

Tissue Antigens. 2004 Sep;64(3):286-92.

PMID:
15304010
41.

Surgical treatment of multiple skull abscesses associated with coccidioidomycosis.

Baddley JW, Cobbs CS, Pappas PG.

Mycoses. 2004 Feb;47(1-2):69-71.

PMID:
14998403
42.

Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells.

Cobbs CS, Whisenhunt TR, Wesemann DR, Harkins LE, Van Meir EG, Samanta M.

Cancer Res. 2003 Dec 15;63(24):8670-3.

43.

High prevalence of human cytomegalovirus in prostatic intraepithelial neoplasia and prostatic carcinoma.

Samanta M, Harkins L, Klemm K, Britt WJ, Cobbs CS.

J Urol. 2003 Sep;170(3):998-1002.

PMID:
12913758
44.

Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer.

Harkins L, Volk AL, Samanta M, Mikolaenko I, Britt WJ, Bland KI, Cobbs CS.

Lancet. 2002 Nov 16;360(9345):1557-63.

PMID:
12443594
45.

Human cytomegalovirus infection and expression in human malignant glioma.

Cobbs CS, Harkins L, Samanta M, Gillespie GY, Bharara S, King PH, Nabors LB, Cobbs CG, Britt WJ.

Cancer Res. 2002 Jun 15;62(12):3347-50.

46.

Second messengers regulate RGS2 expression which is targeted to the nucleus.

Zmijewski JW, Song L, Harkins L, Cobbs CS, Jope RS.

Biochim Biophys Acta. 2001 Dec 19;1541(3):201-11.

47.

Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: possible functional consequences.

Cobbs CS, Samanta M, Harkins LE, Gillespie GY, Merrick BA, MacMillan-Crow LA.

Arch Biochem Biophys. 2001 Oct 15;394(2):167-72.

PMID:
11594730
48.

Oxidative stress and heat shock stimulate RGS2 expression in 1321N1 astrocytoma cells.

Zmijewski JW, Song L, Harkins L, Cobbs CS, Jope RS.

Arch Biochem Biophys. 2001 Aug 15;392(2):192-6.

PMID:
11488592
49.

Intrasellar cavernous hemangioma. Case report.

Cobbs CS, Wilson CB.

J Neurosurg. 2001 Mar;94(3):520-2.

PMID:
11235960
50.

p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo.

Wang D, Grammer JR, Cobbs CS, Stewart JE Jr, Liu Z, Rhoden R, Hecker TP, Ding Q, Gladson CL.

J Cell Sci. 2000 Dec;113 Pt 23:4221-30.

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