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Items: 1 to 50 of 51

1.

Gastrointestinal Manifestations in Common Variable Immunodeficiency (CVID) are Associated with An Altered Immunophenotype Including B- and T-cell Dysregulation.

Barmettler S, Ong MS, Farmer JR, Yang N, Cobbold M, Walter JE, Long A, Camargo CA Jr.

J Allergy Clin Immunol Pract. 2019 Nov 5. pii: S2213-2198(19)30915-8. doi: 10.1016/j.jaip.2019.10.024. [Epub ahead of print] No abstract available.

PMID:
31704440
2.

Dual Programmed Death Receptor-1 and Vascular Endothelial Growth Factor Receptor-2 Blockade Promotes Vascular Normalization and Enhances Antitumor Immune Responses in Hepatocellular Carcinoma.

Shigeta K, Datta M, Hato T, Kitahara S, Chen IX, Matsui A, Kikuchi H, Mamessier E, Aoki S, Ramjiawan RR, Ochiai H, Bardeesy N, Huang P, Cobbold M, Zhu AX, Jain RK, Duda DG.

Hepatology. 2019 Aug 5. doi: 10.1002/hep.30889. [Epub ahead of print]

PMID:
31378984
3.

Aberrant X chromosome skewing and acquired clonal hematopoiesis in adult-onset common variable immunodeficiency.

Wong GK, Barmettler S, Heather JM, Millar D, Penny SA, Huissoon A, Richter A, Cobbold M.

JCI Insight. 2019 Jul 25;4(14). pii: 127614. doi: 10.1172/jci.insight.127614. eCollection 2019 Jul 25.

4.

Differential Association Between Circulating Lymphocyte Populations With Outcome After Radiation Therapy in Subtypes of Liver Cancer.

Grassberger C, Hong TS, Hato T, Yeap BY, Wo JY, Tracy M, Bortfeld T, Wolfgang JA, Eyler CE, Goyal L, Clark JW, Crane CH, Koay EJ, Cobbold M, DeLaney TF, Jain RK, Zhu AX, Duda DG.

Int J Radiat Oncol Biol Phys. 2018 Aug 1;101(5):1222-1225. doi: 10.1016/j.ijrobp.2018.04.026. Epub 2018 Apr 17.

5.

Can smart nanomedicine deliver effective targeted cytotoxic treatments to hepatocellular carcinomas while reducing the liver damage?

Aoki S, Cobbold M, Zhu AX, Duda DG.

Hepatology. 2018 Mar;67(3):826-828. doi: 10.1002/hep.29617. Epub 2018 Jan 30. No abstract available.

6.

The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.

Mohammed F, Stones DH, Zarling AL, Willcox CR, Shabanowitz J, Cummings KL, Hunt DF, Cobbold M, Engelhard VH, Willcox BE.

Oncotarget. 2017 Apr 8;8(33):54160-54172. doi: 10.18632/oncotarget.16952. eCollection 2017 Aug 15.

7.

Immune dysregulation in immunodeficiency disorders: The role of T-cell receptor sequencing.

Wong GK, Heather JM, Barmettler S, Cobbold M.

J Autoimmun. 2017 Jun;80:1-9. doi: 10.1016/j.jaut.2017.04.002. Epub 2017 Apr 8. Review.

PMID:
28400082
8.

Identification of Glycopeptides as Posttranslationally Modified Neoantigens in Leukemia.

Malaker SA, Penny SA, Steadman LG, Myers PT, Loke JC, Raghavan M, Bai DL, Shabanowitz J, Hunt DF, Cobbold M.

Cancer Immunol Res. 2017 May;5(5):376-384. doi: 10.1158/2326-6066.CIR-16-0280. Epub 2017 Mar 17.

9.

Development of a rapid and quantitative lateral flow assay for the simultaneous measurement of serum κ and λ immunoglobulin free light chains (FLC): inception of a new near-patient FLC screening tool.

Campbell JP, Heaney JL, Shemar M, Baldwin D, Griffin AE, Oldridge E, Goodall M, Afzal Z, Plant T, Cobbold M, Jefferis R, Jacobs JF, Hand C, Drayson MT.

Clin Chem Lab Med. 2017 Mar 1;55(3):424-434. doi: 10.1515/cclm-2016-0194.

PMID:
27505089
10.

Accelerated Loss of TCR Repertoire Diversity in Common Variable Immunodeficiency.

Wong GK, Millar D, Penny S, Heather JM, Mistry P, Buettner N, Bryon J, Huissoon AP, Cobbold M.

J Immunol. 2016 Sep 1;197(5):1642-9. doi: 10.4049/jimmunol.1600526. Epub 2016 Aug 1.

11.

Inhibition of Histone Deacetylase 6 Reveals a Potent Immunosuppressant Effect in Models of Transplantation.

Ellis JD, Neil DA, Inston NG, Jenkinson E, Drayson MT, Hampson P, Shuttleworth SJ, Ready AR, Cobbold M.

Transplantation. 2016 Aug;100(8):1667-74. doi: 10.1097/TP.0000000000001208.

PMID:
27222932
12.

Hand-assisted Laparoscopic Donor Nephrectomy and Cytokine Changes.

Field M, Guy A, Ready AR, Cobbold M, Inston N.

Transplant Proc. 2015 Nov;47(9):2690-3. doi: 10.1016/j.transproceed.2015.10.001.

PMID:
26680073
13.

Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets.

Hitchcock JR, Cook CN, Bobat S, Ross EA, Flores-Langarica A, Lowe KL, Khan M, Dominguez-Medina CC, Lax S, Carvalho-Gaspar M, Hubscher S, Rainger GE, Cobbold M, Buckley CD, Mitchell TJ, Mitchell A, Jones ND, Van Rooijen N, Kirchhofer D, Henderson IR, Adams DH, Watson SP, Cunningham AF.

J Clin Invest. 2015 Dec;125(12):4429-46. doi: 10.1172/JCI79070. Epub 2015 Nov 16.

14.

Accounting for filter bandwidth improves the quantitative accuracy of bioluminescence tomography.

Taylor SL, Mason SK, Glinton SL, Cobbold M, Dehghani H.

J Biomed Opt. 2015 Sep;20(9):096001. doi: 10.1117/1.JBO.20.9.096001.

15.

Complementary IMAC enrichment methods for HLA-associated phosphopeptide identification by mass spectrometry.

Abelin JG, Trantham PD, Penny SA, Patterson AM, Ward ST, Hildebrand WH, Cobbold M, Bai DL, Shabanowitz J, Hunt DF.

Nat Protoc. 2015 Sep;10(9):1308-18. doi: 10.1038/nprot.2015.086. Epub 2015 Aug 6.

16.

Stage I mycosis fungoides: frequent association with a favourable prognosis but disease progression and disease-specific mortality may occur.

Wernham AG, Shah F, Amel-Kashipaz R, Cobbold M, Scarisbrick J.

Br J Dermatol. 2015 Nov;173(5):1295-7. doi: 10.1111/bjd.13939. Epub 2015 Aug 31. No abstract available.

PMID:
26053896
17.

Metabolomic perfusate analysis during kidney machine perfusion: the pig provides an appropriate model for human studies.

Nath J, Guy A, Smith TB, Cobbold M, Inston NG, Hodson J, Tennant DA, Ludwig C, Ready AR.

PLoS One. 2014 Dec 12;9(12):e114818. doi: 10.1371/journal.pone.0114818. eCollection 2014.

18.

Metabolomic analysis of perfusate during hypothermic machine perfusion of human cadaveric kidneys.

Guy AJ, Nath J, Cobbold M, Ludwig C, Tennant DA, Inston NG, Ready AR.

Transplantation. 2015 Apr;99(4):754-9. doi: 10.1097/TP.0000000000000398.

PMID:
25222017
19.

Tracking genomic cancer evolution for precision medicine: the lung TRACERx study.

Jamal-Hanjani M, Hackshaw A, Ngai Y, Shaw J, Dive C, Quezada S, Middleton G, de Bruin E, Le Quesne J, Shafi S, Falzon M, Horswell S, Blackhall F, Khan I, Janes S, Nicolson M, Lawrence D, Forster M, Fennell D, Lee SM, Lester J, Kerr K, Muller S, Iles N, Smith S, Murugaesu N, Mitter R, Salm M, Stuart A, Matthews N, Adams H, Ahmad T, Attanoos R, Bennett J, Birkbak NJ, Booton R, Brady G, Buchan K, Capitano A, Chetty M, Cobbold M, Crosbie P, Davies H, Denison A, Djearman M, Goldman J, Haswell T, Joseph L, Kornaszewska M, Krebs M, Langman G, MacKenzie M, Millar J, Morgan B, Naidu B, Nonaka D, Peggs K, Pritchard C, Remmen H, Rowan A, Shah R, Smith E, Summers Y, Taylor M, Veeriah S, Waller D, Wilcox B, Wilcox M, Woolhouse I, McGranahan N, Swanton C.

PLoS Biol. 2014 Jul 8;12(7):e1001906. doi: 10.1371/journal.pbio.1001906. eCollection 2014 Jul.

20.

Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function.

Ross EA, Flores-Langarica A, Bobat S, Coughlan RE, Marshall JL, Hitchcock JR, Cook CN, Carvalho-Gaspar MM, Mitchell AM, Clarke M, Garcia P, Cobbold M, Mitchell TJ, Henderson IR, Jones ND, Anderson G, Buckley CD, Cunningham AF.

Eur J Immunol. 2014 Aug;44(8):2318-30. doi: 10.1002/eji.201344350. Epub 2014 Jun 11.

21.

Urinary biomarkers of acute kidney injury in deceased organ donors--kidney injury molecule-1 as an adjunct to predicting outcome.

Field M, Dronavalli V, Mistry P, Drayson M, Ready A, Cobbold M, Inston N.

Clin Transplant. 2014 Jul;28(7):808-15. doi: 10.1111/ctr.12383. Epub 2014 Jun 3.

PMID:
24801162
22.

The use of NGAL and IP-10 in the prediction of early acute rejection in highly sensitized patients following HLA-incompatible renal transplantation.

Field M, Lowe D, Cobbold M, Higgins R, Briggs D, Inston N, Ready AR.

Transpl Int. 2014 Apr;27(4):362-70. doi: 10.1111/tri.12266. Epub 2014 Feb 11.

23.

MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia.

Cobbold M, De La Peña H, Norris A, Polefrone JM, Qian J, English AM, Cummings KL, Penny S, Turner JE, Cottine J, Abelin JG, Malaker SA, Zarling AL, Huang HW, Goodyear O, Freeman SD, Shabanowitz J, Pratt G, Craddock C, Williams ME, Hunt DF, Engelhard VH.

Sci Transl Med. 2013 Sep 18;5(203):203ra125. doi: 10.1126/scitranslmed.3006061.

24.

HLA-peptide multimer selection of adenovirus-specific T cells for adoptive T-cell therapy.

Chakupurakal G, Onion D, Bonney S, Cobbold M, Mautner V, Moss P.

J Immunother. 2013 Oct;36(8):423-31. doi: 10.1097/CJI.0b013e3182a8029e.

PMID:
23994889
25.

Development of a highly-sensitive multi-plex assay using monoclonal antibodies for the simultaneous measurement of kappa and lambda immunoglobulin free light chains in serum and urine.

Campbell JP, Cobbold M, Wang Y, Goodall M, Bonney SL, Chamba A, Birtwistle J, Plant T, Afzal Z, Jefferis R, Drayson MT.

J Immunol Methods. 2013 May 31;391(1-2):1-13. doi: 10.1016/j.jim.2013.01.014. Epub 2013 Feb 4.

26.

Purification of antibodies to O antigen of Salmonella Typhimurium from human serum by affinity chromatography.

O'Shaughnessy CM, Micoli F, Gavini M, Goodall M, Cobbold M, Saul A, Maclennan CA.

J Immunol Methods. 2013 Jan 31;387(1-2):199-210. doi: 10.1016/j.jim.2012.10.015. Epub 2012 Nov 8.

27.

Measurement of antibodies to pneumococcal, meningococcal and haemophilus polysaccharides, and tetanus and diphtheria toxoids using a 19-plexed assay.

Whitelegg AM, Birtwistle J, Richter A, Campbell JP, Turner JE, Ahmed TM, Giles LJ, Fellows M, Plant T, Ferraro AJ, Cobbold M, Drayson MT, MacLennan CA.

J Immunol Methods. 2012 Mar 30;377(1-2):37-46. doi: 10.1016/j.jim.2012.01.007. Epub 2012 Jan 24.

PMID:
22293629
28.

Persistent viral infection in humans can drive high frequency low-affinity T-cell expansions.

Khan N, Cobbold M, Cummerson J, Moss PA.

Immunology. 2010 Dec;131(4):537-48. doi: 10.1111/j.1365-2567.2010.03326.x. Epub 2010 Aug 16.

29.

Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults.

MacLennan CA, Gilchrist JJ, Gordon MA, Cunningham AF, Cobbold M, Goodall M, Kingsley RA, van Oosterhout JJ, Msefula CL, Mandala WL, Leyton DL, Marshall JL, Gondwe EN, Bobat S, López-Macías C, Doffinger R, Henderson IR, Zijlstra EE, Dougan G, Drayson MT, MacLennan IC, Molyneux ME.

Science. 2010 Apr 23;328(5977):508-12. doi: 10.1126/science.1180346.

30.

Adenovirus vector-specific T cells demonstrate a unique memory phenotype with high proliferative potential and coexpression of CCR5 and integrin alpha4beta7.

Chakupurakal G, Onion D, Cobbold M, Mautner V, Moss PA.

AIDS. 2010 Jan 16;24(2):205-10. doi: 10.1097/QAD.0b013e328333addf.

PMID:
19864932
31.

Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition.

Nicholls S, Piper KP, Mohammed F, Dafforn TR, Tenzer S, Salim M, Mahendra P, Craddock C, van Endert P, Schild H, Cobbold M, Engelhard VH, Moss PA, Willcox BE.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3889-94. doi: 10.1073/pnas.0900411106. Epub 2009 Feb 20.

32.

Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self.

Mohammed F, Cobbold M, Zarling AL, Salim M, Barrett-Wilt GA, Shabanowitz J, Hunt DF, Engelhard VH, Willcox BE.

Nat Immunol. 2008 Nov;9(11):1236-43. doi: 10.1038/ni.1660. Epub 2008 Oct 5.

33.

Synthesis and ex vivo profiling of chemically modified cytomegalovirus CMVpp65 epitopes.

Jones MA, Notta JK, Cobbold M, Palendira M, Hislop AD, Wilkie J, Snaith JS.

J Pept Sci. 2008 Mar;14(3):313-20.

PMID:
17929331
34.

Power output and muscle myosin heavy chain composition in young and elderly men.

Pearson SJ, Cobbold M, Orrell RW, Harridge SD.

Med Sci Sports Exerc. 2006 Sep;38(9):1601-7.

PMID:
16960521
35.

Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation.

Amrolia PJ, Muccioli-Casadei G, Huls H, Adams S, Durett A, Gee A, Yvon E, Weiss H, Cobbold M, Gaspar HB, Rooney C, Kuehnle I, Ghetie V, Schindler J, Krance R, Heslop HE, Veys P, Vitetta E, Brenner MK.

Blood. 2006 Sep 15;108(6):1797-808. Epub 2006 Jun 1.

36.

In treatment-naïve and antiretroviral-treated subjects with HIV, reduced plasma adiponectin is associated with a reduced fractional clearance rate of VLDL, IDL and LDL apolipoprotein B-100.

Das S, Shahmanesh M, Stolinski M, Shojaee-Moradie F, Jefferson W, Jackson NC, Cobbold M, Nightingale P, Umpleby AM.

Diabetologia. 2006 Mar;49(3):538-42. Epub 2006 Jan 24.

PMID:
16432707
37.

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers.

Cobbold M, Khan N, Pourgheysari B, Tauro S, McDonald D, Osman H, Assenmacher M, Billingham L, Steward C, Crawley C, Olavarria E, Goldman J, Chakraverty R, Mahendra P, Craddock C, Moss PA.

J Exp Med. 2005 Aug 1;202(3):379-86.

38.

Selection of CMV-specific CD8+ and CD4+ T cells by mini-EBV-transformed B cell lines.

Wiesner M, Zentz C, Hammer MH, Cobbold M, Kern F, Kolb HJ, Hammerschmidt W, Zeidler R, Moosmann A.

Eur J Immunol. 2005 Jul;35(7):2110-21.

40.

Effects of resistance training on myosin function studied by the in vitro motility assay in young and older men.

Canepari M, Rossi R, Pellegrino MA, Orrell RW, Cobbold M, Harridge S, Bottinelli R.

J Appl Physiol (1985). 2005 Jun;98(6):2390-5. Epub 2005 Jan 27.

41.

Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection.

Khan N, Hislop A, Gudgeon N, Cobbold M, Khanna R, Nayak L, Rickinson AB, Moss PA.

J Immunol. 2004 Dec 15;173(12):7481-9.

42.

Power output of the lower limb during variable inertial loading: a comparison between methods using single and repeated contractions.

Pearson SJ, Cobbold M, Harridge SD.

Eur J Appl Physiol. 2004 Jun;92(1-2):176-81. Epub 2004 Mar 26.

PMID:
15045501
43.

The cellular immunotherapy of viral infection.

Moss PA, Cobbold M, Craddock C.

Transfus Med. 2003 Dec;13(6):405-15. Review.

PMID:
14651746
44.

Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise.

Hameed M, Orrell RW, Cobbold M, Goldspink G, Harridge SD.

J Physiol. 2003 Feb 15;547(Pt 1):247-54. Epub 2002 Dec 20.

45.

B cells immortalized by a mini-Epstein-Barr virus encoding a foreign antigen efficiently reactivate specific cytotoxic T cells.

Moosmann A, Khan N, Cobbold M, Zentz C, Delecluse HJ, Hollweck G, Hislop AD, Blake NW, Croom-Carter D, Wollenberg B, Moss PA, Zeidler R, Rickinson AB, Hammerschmidt W.

Blood. 2002 Sep 1;100(5):1755-64.

PMID:
12176897
46.

Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.

Khan N, Shariff N, Cobbold M, Bruton R, Ainsworth JA, Sinclair AJ, Nayak L, Moss PA.

J Immunol. 2002 Aug 15;169(4):1984-92.

47.

Muscle function in elite master weightlifters.

Pearson SJ, Young A, Macaluso A, Devito G, Nimmo MA, Cobbold M, Harridge SD.

Med Sci Sports Exerc. 2002 Jul;34(7):1199-206.

PMID:
12131263
48.
49.

Survival after bone-marrow transplantation.

Cwynarski K, Craddock C, Cobbold M, Apperley J, Goldman J.

Lancet. 2002 Mar 9;359(9309):887-8. No abstract available.

PMID:
11897306
50.

Purification of cytomegalovirus-specific CD8 T cells from peripheral blood using HLA-peptide tetramers.

Keenan RD, Ainsworth J, Khan N, Bruton R, Cobbold M, Assenmacher M, Milligan DW, Moss PA.

Br J Haematol. 2001 Nov;115(2):428-34.

PMID:
11703346

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