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Prolongation of atrio-ventricular node conduction in a rabbit model of ischaemic cardiomyopathy: Role of fibrosis and connexin remodelling.

Nisbet AM, Camelliti P, Walker NL, Burton FL, Cobbe SM, Kohl P, Smith GL.

J Mol Cell Cardiol. 2016 May;94:54-64. doi: 10.1016/j.yjmcc.2016.03.011. Epub 2016 Mar 25.


Long-term impact on healthcare resource utilization of statin treatment, and its cost effectiveness in the primary prevention of cardiovascular disease: a record linkage study.

McConnachie A, Walker A, Robertson M, Marchbank L, Peacock J, Packard CJ, Cobbe SM, Ford I.

Eur Heart J. 2014 Feb;35(5):290-8. doi: 10.1093/eurheartj/eht232. Epub 2013 Jul 9.


Spectral microvolt T-wave alternans testing has no prognostic value in patients recently hospitalized with decompensated heart failure.

Jackson CE, Myles RC, Tsorlalis IK, Dalzell JR, Rocchiccioli JP, Rodgers JR, Spooner RJ, Greenlaw N, Ford I, Gardner RS, Cobbe SM, Petrie MC, McMurray JJ.

Eur J Heart Fail. 2013 Nov;15(11):1253-61. doi: 10.1093/eurjhf/hft085. Epub 2013 May 22.


Amplitude Changes during Ventricular Fibrillation: A Mechanistic Insight.

Caldwell JC, Burton FL, Cobbe SM, Smith GL.

Front Physiol. 2012 May 23;3:147. doi: 10.3389/fphys.2012.00147. eCollection 2012.


Microvolt T-wave alternans testing has no role at present in guiding therapy for patients at high risk of ventricular arrhythmias.

Jackson CE, Myles RC, Cobbe SM, Petrie MC, McMurray JJ.

J Am Coll Cardiol. 2012 Feb 28;59(9):856. doi: 10.1016/j.jacc.2011.10.897. No abstract available.


Profile of microvolt T-wave alternans testing in 1003 patients hospitalized with heart failure.

Jackson CE, Myles RC, Tsorlalis IK, Dalzell JR, Spooner RJ, Rodgers JR, Bezlyak V, Greenlaw N, Ford I, Cobbe SM, Petrie MC, McMurray JJ.

Eur J Heart Fail. 2012 Apr;14(4):377-86. doi: 10.1093/eurjhf/hfs010. Epub 2012 Feb 14.


The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes.

Ford I, Mooijaart SP, Lloyd S, Murray HM, Westendorp RG, de Craen AJ, Packard CJ, Buckley B, Barlow C, Preiss D, Cobbe SM, Stott DJ, Sattar N.

Int J Epidemiol. 2011 Dec;40(6):1530-8. doi: 10.1093/ije/dyr172. Epub 2011 Nov 17.


Isoprenaline increases the slopes of restitution trajectory in the conscious rabbit with ischemic heart failure.

Kimotsuki T, Niwa N, Hicks MN, Dunne M, Cobbe SM, Watanabe MA.

J Biol Phys. 2010 Jun;36(3):299-315. doi: 10.1007/s10867-009-9185-5. Epub 2010 Jan 15.


Slowing of Electrical Activity in Ventricular Fibrillation is Not Associated with Increased Defibrillation Energies in the Isolated Rabbit Heart.

Caldwell JC, Burton FL, Cobbe SM, Smith GL.

Front Physiol. 2011 Apr 6;2:11. doi: 10.3389/fphys.2011.00011. eCollection 2011.


Alternans of action potential duration and amplitude in rabbits with left ventricular dysfunction following myocardial infarction.

Myles RC, Burton FL, Cobbe SM, Smith GL.

J Mol Cell Cardiol. 2011 Mar;50(3):510-21. doi: 10.1016/j.yjmcc.2010.11.019. Epub 2010 Dec 9.


Microvolt T-wave alternans in end-stage renal disease patients--associations with uremic cardiomyopathy.

Patel RK, Mark PB, Halliday C, Steedman T, Dargie HJ, Cobbe SM, Jardine AG.

Clin J Am Soc Nephrol. 2011 Mar;6(3):519-27. doi: 10.2215/CJN.06370710. Epub 2010 Nov 18.


Effect of activation sequence on transmural patterns of repolarization and action potential duration in rabbit ventricular myocardium.

Myles RC, Bernus O, Burton FL, Cobbe SM, Smith GL.

Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1812-22. doi: 10.1152/ajpheart.00518.2010. Epub 2010 Oct 1.


Scottish survey of public place defibrillators.

Ashimi AO, Cobbe SM, Pell JP.

Scott Med J. 2010 Aug;55(3):8-10.


I-123 MIBG cardiac uptake measurements: limitations of collimator choice and scatter correction in the clinical context.

Fletcher AM, Motherwell DW, Small AD, McCurrach GM, Goodfield NE, Petrie MC, Martin W, Cobbe SM.

Nucl Med Commun. 2010 Jul;31(7):629-36. doi: 10.1097/MNM.0b013e3283375639.


Low serum cortisol predicts early death after acute myocardial infarction.

Reynolds RM, Walker BR, Haw S, Newby DE, Mackay DF, Cobbe SM, Pell AC, Fischbacher C, Pringle S, Murdoch D, Dunn F, Oldroyd K, Macintyre P, O'Rourke B, Pell JP.

Crit Care Med. 2010 Mar;38(3):973-5. doi: 10.1097/CCM.0b013e3181cdf6de.


Red cell distribution width has incremental prognostic value to B-type natriuretic peptide in acute heart failure.

Jackson CE, Dalzell JR, Bezlyak V, Tsorlalis IK, Myles RC, Spooner R, Ford I, Petrie MC, Cobbe SM, McMurray JJ.

Eur J Heart Fail. 2009 Dec;11(12):1152-4. doi: 10.1093/eurjhf/hfp157. No abstract available.


Paroxysmal bidirectional ventricular tachycardia with tachycardiomyopathy in a pregnant woman.

Walker NL, Cobbe SM, McGavigan AD.

Acta Cardiol. 2009 Jun;64(3):419-22.


Atrial fibrillation and heart failure in cardiology practice: reciprocal impact and combined management from the perspective of atrial fibrillation: results of the Euro Heart Survey on atrial fibrillation.

Nieuwlaat R, Eurlings LW, Cleland JG, Cobbe SM, Vardas PE, Capucci A, López-Sendòn JL, Meeder JG, Pinto YM, Crijns HJ.

J Am Coll Cardiol. 2009 May 5;53(18):1690-8. doi: 10.1016/j.jacc.2009.01.055.


Rosuvastatin and cardiovascular events in patients undergoing hemodialysis.

Fellström BC, Jardine AG, Schmieder RE, Holdaas H, Bannister K, Beutler J, Chae DW, Chevaile A, Cobbe SM, Grönhagen-Riska C, De Lima JJ, Lins R, Mayer G, McMahon AW, Parving HH, Remuzzi G, Samuelsson O, Sonkodi S, Sci D, Süleymanlar G, Tsakiris D, Tesar V, Todorov V, Wiecek A, Wüthrich RP, Gottlow M, Johnsson E, Zannad F; AURORA Study Group.

N Engl J Med. 2009 Apr 2;360(14):1395-407. doi: 10.1056/NEJMoa0810177. Epub 2009 Mar 30. Erratum in: N Engl J Med. 2010 Apr 15;362(15):1450.


Adipocytokines and risk of stroke in older people: a nested case-control study.

Stott DJ, Welsh P, Rumley A, Robertson M, Ford I, Sattar N, Westendorp RG, Jukema JW, Cobbe SM, Lowe GD.

Int J Epidemiol. 2009 Feb;38(1):253-61. doi: 10.1093/ije/dyn215. Epub 2008 Oct 24.


Validity of self-reported smoking status: Comparison of patients admitted to hospital with acute coronary syndrome and the general population.

Pell JP, Haw SJ, Cobbe SM, Newby DE, Pell AC, Oldroyd KG, Murdoch DL, Pringle SD, Dunn FG, Macintyre PD, Gilbert TJ, Fischbacher CM, Borland W.

Nicotine Tob Res. 2008 May;10(5):861-6. doi: 10.1080/14622200802023858.


The link between repolarisation alternans and ventricular arrhythmia: does the cellular phenomenon extend to the clinical problem?

Myles RC, Burton FL, Cobbe SM, Smith GL.

J Mol Cell Cardiol. 2008 Jul;45(1):1-10. doi: 10.1016/j.yjmcc.2008.03.024. Epub 2008 Apr 9. Review.


Prognosis, disease progression, and treatment of atrial fibrillation patients during 1 year: follow-up of the Euro Heart Survey on atrial fibrillation.

Nieuwlaat R, Prins MH, Le Heuzey JY, Vardas PE, Aliot E, Santini M, Cobbe SM, Widdershoven JW, Baur LH, Lévy S, Crijns HJ.

Eur Heart J. 2008 May;29(9):1181-9. doi: 10.1093/eurheartj/ehn139. Epub 2008 Apr 7.


Paced ventricular electrogram fractionation predicts sudden cardiac death in hypertrophic cardiomyopathy.

Saumarez RC, Pytkowski M, Sterlinski M, Bourke JP, Clague JR, Cobbe SM, Connelly DT, Griffith MJ, McKeown PP, McLeod K, Morgan JM, Sadoul N, Chojnowska L, Huang CL, Grace AA.

Eur Heart J. 2008 Jul;29(13):1653-61. doi: 10.1093/eurheartj/ehn111. Epub 2008 Apr 2.


Is microvolt T-wave alternans the answer to risk stratification in heart failure?

Myles RC, Jackson CE, Tsorlalis I, Petrie MC, McMurray JJ, Cobbe SM.

Circulation. 2007 Dec 18;116(25):2984-91. Review. No abstract available.


Association between apolipoprotein E4 and cognitive decline in elderly adults.

Packard CJ, Westendorp RG, Stott DJ, Caslake MJ, Murray HM, Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Jolles J, Perry IJ, Sweeney BJ, Twomey C; Prospective Study of Pravastatin in the Elderly at Risk Group.

J Am Geriatr Soc. 2007 Nov;55(11):1777-85.


Long-term follow-up of the West of Scotland Coronary Prevention Study.

Ford I, Murray H, Packard CJ, Shepherd J, Macfarlane PW, Cobbe SM; West of Scotland Coronary Prevention Study Group.

N Engl J Med. 2007 Oct 11;357(15):1477-86.


Reproducibility and repeatability of peripheral microvascular assessment using iontophoresis in conjunction with laser Doppler imaging.

Jadhav S, Sattar N, Petrie JR, Cobbe SM, Ferrell WR.

J Cardiovasc Pharmacol. 2007 Sep;50(3):343-9.


The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases.

Emerging Risk Factors Collaboration, Danesh J, Erqou S, Walker M, Thompson SG, Tipping R, Ford C, Pressel S, Walldius G, Jungner I, Folsom AR, Chambless LE, Knuiman M, Whincup PH, Wannamethee SG, Morris RW, Willeit J, Kiechl S, Santer P, Mayr A, Wald N, Ebrahim S, Lawlor DA, Yarnell JW, Gallacher J, Casiglia E, Tikhonoff V, Nietert PJ, Sutherland SE, Bachman DL, Keil JE, Cushman M, Psaty BM, Tracy RP, Tybjaerg-Hansen A, Nordestgaard BG, Frikke-Schmidt R, Giampaoli S, Palmieri L, Panico S, Vanuzzo D, Pilotto L, Simons L, McCallum J, Friedlander Y, Fowkes FG, Lee AJ, Smith FB, Taylor J, Guralnik J, Phillips C, Wallace R, Blazer D, Khaw KT, Jansson JH, Donfrancesco C, Salomaa V, Harald K, Jousilahti P, Vartiainen E, Woodward M, D'Agostino RB, Wolf PA, Vasan RS, Pencina MJ, Bladbjerg EM, Jorgensen T, Moller L, Jespersen J, Dankner R, Chetrit A, Lubin F, Rosengren A, Wilhelmsen L, Lappas G, Eriksson H, Bjorkelund C, Cremer P, Nagel D, Tilvis R, Strandberg T, Rodriguez B, Bouter LM, Heine RJ, Dekker JM, Nijpels G, Stehouwer CD, Rimm E, Pai J, Sato S, Iso H, Kitamura A, Noda H, Goldbourt U, Salomaa V, Salonen JT, Nyyssönen K, Tuomainen TP, Deeg D, Poppelaars JL, Meade T, Cooper J, Hedblad B, Berglund G, Engstrom G, Döring A, Koenig W, Meisinger C, Mraz W, Kuller L, Selmer R, Tverdal A, Nystad W, Gillum R, Mussolino M, Hankinson S, Manson J, De Stavola B, Knottenbelt C, Cooper JA, Bauer KA, Rosenberg RD, Sato S, Naito Y, Holme I, Nakagawa H, Miura H, Ducimetiere P, Jouven X, Crespo C, Garcia-Palmieri M, Amouyel P, Arveiler D, Evans A, Ferrieres J, Schulte H, Assmann G, Shepherd J, Packard C, Sattar N, Cantin B, Lamarche B, Després JP, Dagenais GR, Barrett-Connor E, Wingard D, Bettencourt R, Gudnason V, Aspelund T, Sigurdsson G, Thorsson B, Trevisan M, Witteman J, Kardys I, Breteler M, Hofman A, Tunstall-Pedoe H, Tavendale R, Lowe GD, Ben-Shlomo Y, Howard BV, Zhang Y, Best L, Umans J, Onat A, Meade TW, Njolstad I, Mathiesen E, Lochen ML, Wilsgaard T, Gaziano JM, Stampfer M, Ridker P, Ulmer H, Diem G, Concin H, Rodeghiero F, Tosetto A, Brunner E, Shipley M, Buring J, Cobbe SM, Ford I, Robertson M, He Y, Ibanez AM, Feskens EJ, Kromhout D, Collins R, Di Angelantonio E, Kaptoge S, Lewington S, Orfei L, Pennells L, Perry P, Ray K, Sarwar N, Scherman M, Thompson A, Watson S, Wensley F, White IR, Wood AM.

Eur J Epidemiol. 2007;22(12):839-69. Epub 2007 Sep 18.


Heterogeneity of ventricular fibrillation dominant frequency during global ischemia in isolated rabbit hearts.

Caldwell J, Burton FL, Smith GL, Cobbe SM.

J Cardiovasc Electrophysiol. 2007 Aug;18(8):854-61. Epub 2007 Jun 6.


Mapping of epicardial activation in a rabbit model of chronic myocardial infarction:.

Walker NL, Burton FL, Kettlewell S, Smith GL, Cobbe SM.

J Cardiovasc Electrophysiol. 2007 Aug;18(8):862-8. Epub 2007 May 30.


The introduction of a chest pain nurse and fast-track troponin service reduces the length of stay of patients presenting with chest pain.

Motherwell DW, Rogers J, Kellagher M, Craig D, O'Reilly DS, Cobbe SM.

Scott Med J. 2007 May;52(2):6-9.


Prediction of cognitive dysfunction after resuscitation from out-of-hospital cardiac arrest using serum neuron-specific enolase and protein S-100.

Grubb NR, Simpson C, Sherwood RA, Abraha HD, Cobbe SM, O'Carroll RE, Deary I, Fox KA.

Heart. 2007 Oct;93(10):1268-73. Epub 2007 May 13.


Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER study.

Trompet S, Pons D, DE Craen AJ, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Cobbe SM, Bollen EL, Buckley BM, Ford I, Hyland M, Gaw A, Macfarlane PW, Packard CJ, Norrie J, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG, Jukema JW.

Ann N Y Acad Sci. 2007 Apr;1100:189-98.


C-reactive protein and prediction of coronary heart disease and global vascular events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).

Sattar N, Murray HM, McConnachie A, Blauw GJ, Bollen EL, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Murphy MB, Packard CJ, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG, Shepherd J; PROSPER Study Group.

Circulation. 2007 Feb 27;115(8):981-9. Epub 2007 Feb 5.


Cost-effectiveness of automated external defibrillators in public places: con.

Pell JP, Walker A, Cobbe SM.

Curr Opin Cardiol. 2007 Jan;22(1):5-10. Review.


Abnormal haemoglobin levels in acute coronary syndromes.

Bindra K, Berry C, Rogers J, Stewart N, Watts M, Christie J, Cobbe SM, Eteiba H.

QJM. 2006 Dec;99(12):851-62.


How does thrombolysis increase defibrillation success?

Caldwell JC, Smith GL, Cobbe SM.

Med Hypotheses. 2007;68(5):1183-4. Epub 2006 Nov 22. No abstract available.


123I- Metaiodobenzylguanidine in chronic heart failure: Is there a clinical use?

Motherwell DW, Petrie MC, Martin W, Cobbe SM.

Nucl Med Commun. 2006 Dec;27(12):927-31. No abstract available.


Effects of metformin on microvascular function and exercise tolerance in women with angina and normal coronary arteries: a randomized, double-blind, placebo-controlled study.

Jadhav S, Ferrell W, Greer IA, Petrie JR, Cobbe SM, Sattar N.

J Am Coll Cardiol. 2006 Sep 5;48(5):956-63. Epub 2006 Aug 17.


Microvascular function, metabolic syndrome, and novel risk factor status in women with cardiac syndrome X.

Jadhav ST, Ferrell WR, Petrie JR, Scherbakova O, Greer IA, Cobbe SM, Sattar N.

Am J Cardiol. 2006 Jun 15;97(12):1727-31. Epub 2006 Apr 21.


Reductase inhibitor monotherapy for cholesterol reduction lowered the incidence of stroke.

Cobbe SM.

Evid Based Cardiovasc Med. 1998 Mar;2(1):20. No abstract available.


Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER).

Packard CJ, Ford I, Robertson M, Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG; PROSPER Study Group.

Circulation. 2005 Nov 15;112(20):3058-65. Epub 2005 Nov 7.


Post-discharge survival following pre-hospital cardiopulmonary arrest due to cardiac aetiology: temporal trends and impact of changes in clinical management.

Pell JP, Corstorphine M, McConnachie A, Walker NL, Caldwell JC, Marsden AK, Grubb NR, Cobbe SM.

Eur Heart J. 2006 Feb;27(4):406-12. Epub 2005 Oct 17.


Junctional rhythm--a suitable surrogate endpoint in catheter ablation of atrioventricular nodal reentry tachycardia?

McGavigan AD, Rae AP, Cobbe SM, Rankin AC.

Pacing Clin Electrophysiol. 2005 Oct;28(10):1052-4.


Effect of pravastatin on rate of kidney function loss in people with or at risk for coronary disease.

Tonelli M, Isles C, Craven T, Tonkin A, Pfeffer MA, Shepherd J, Sacks FM, Furberg C, Cobbe SM, Simes J, West M, Packard C, Curhan GC.

Circulation. 2005 Jul 12;112(2):171-8. Epub 2005 Jul 5.


A randomized comparison of the effects of aspirin and clopidogrel on thrombotic risk factors and C-reactive protein following myocardial infarction: the CADET trial.

Woodward M, Lowe GD, Francis LM, Rumley A, Cobbe SM; CADET Study Investigators.

J Thromb Haemost. 2004 Nov;2(11):1934-40.


Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. 1995.

Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, MacFarlane PW, McKillop JH, Packard CJ; West of Scotland Coronary Prevention Study Group.

Atheroscler Suppl. 2004 Oct;5(3):91-7. No abstract available.


Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently of classical risk factors, metabolic syndrome, and C-reactive protein in the west of Scotland coronary prevention study.

Sattar N, Scherbakova O, Ford I, O'Reilly DS, Stanley A, Forrest E, Macfarlane PW, Packard CJ, Cobbe SM, Shepherd J; west of Scotland coronary prevention study.

Diabetes. 2004 Nov;53(11):2855-60.

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